메뉴 건너뛰기




Volumn 168, Issue MAY SUPPL. 29, 1996, Pages 23-31

Pre-clinical pharmacology of atypical antipsychotic drugs: A selective review

Author keywords

[No Author keywords available]

Indexed keywords

AMPEROZIDE; CHLORPROMAZINE; CLOZAPINE; DOPAMINE; FLUPERLAPINE; HALOPERIDOL; LOXAPINE; NEUROLEPTIC AGENT; RISPERIDONE; SEROTONIN RECEPTOR; THIORIDAZINE;

EID: 0029954801     PISSN: 00071250     EISSN: None     Source Type: Journal    
DOI: 10.1192/s0007125000298280     Document Type: Review
Times cited : (69)

References (91)
  • 2
    • 0023036497 scopus 로고
    • Evidence for different states of the dopamine D1 receptor: Clozapine and fluperlapine may preferentially label an adenylate cyclase-coupled state of the D1 receptor
    • ANDERSEN, P. H. & BRAESTRUP, C. (1986) Evidence for different states of the dopamine D1 receptor: clozapine and fluperlapine may preferentially label an adenylate cyclase-coupled state of the D1 receptor. Journal of Neurochemistry, 47, 1822-1831.
    • (1986) Journal of Neurochemistry , vol.47 , pp. 1822-1831
    • Andersen, P.H.1    Braestrup, C.2
  • 4
    • 0025948534 scopus 로고
    • Comparison of the effects of various typical and atypical antipsychotic drugs on the suppressant action of 2-methyl-serotonin on medial prefrontal cortical cells in the rat
    • ASHBY, C. R., JR, MINABE, Y., EDWARDS, I., et al (1991) Comparison of the effects of various typical and atypical antipsychotic drugs on the suppressant action of 2-methyl-serotonin on medial prefrontal cortical cells in the rat. Synapse, 8, 155-161.
    • (1991) Synapse , vol.8 , pp. 155-161
    • Ashby Jr., C.R.1    Minabe, Y.2    Edwards, I.3
  • 5
    • 0018647518 scopus 로고
    • Effect of drugs influencing central serotonergic mechanisms or haloperidol-induced catalepsy
    • BALSARA, J. J., JAELHAV, J. H. & CHANDORKAR, A. G. (1979) Effect of drugs influencing central serotonergic mechanisms or haloperidol-induced catalepsy. Psychopharmacology, 22, 67-69.
    • (1979) Psychopharmacology , vol.22 , pp. 67-69
    • Balsara, J.J.1    Jaelhav, J.H.2    Chandorkar, A.G.3
  • 8
    • 0013638032 scopus 로고
    • Clinical overview of risperidone
    • (ed. H. Y. Meltzer), New York: Raven Press
    • BORISON, R. L., DIAMOND, B. I., PATHIRAJA, A. P., et al (1992) Clinical overview of risperidone. In Novel Antipsychotic Drugs (ed. H. Y. Meltzer), pp. 233-239. New York: Raven Press,
    • (1992) Novel Antipsychotic Drugs , pp. 233-239
    • Borison, R.L.1    Diamond, B.I.2    Pathiraja, A.P.3
  • 9
    • 0026062880 scopus 로고
    • Midbrain dopamine system electrophysiological functioning: A review and hypothesis
    • BUNNEY, B. S., CHIODO, L. A. & GRACE, A. A. (1991) Midbrain dopamine system electrophysiological functioning: a review and hypothesis. Synapse, 9, 79-94.
    • (1991) Synapse , vol.9 , pp. 79-94
    • Bunney, B.S.1    Chiodo, L.A.2    Grace, A.A.3
  • 11
    • 0020576408 scopus 로고
    • Typical and atypical neuroleptics: Differential effects of chronic administration on the activity of A9 and A10 midbrain dopaminergic neurons
    • CHIODO, L. A. & BUNNEY, B. S. (1983) Typical and atypical neuroleptics: differential effects of chronic administration on the activity of A9 and A10 midbrain dopaminergic neurons. Journal of Neuroscience, 3, 1607-1619.
    • (1983) Journal of Neuroscience , vol.3 , pp. 1607-1619
    • Chiodo, L.A.1    Bunney, B.S.2
  • 12
    • 0021934560 scopus 로고
    • Possible mechanisms by which repeated clozapine administration differentially affects the activity of two subpopulations of midbrain dopamine neurons
    • _ & _ (1985) Possible mechanisms by which repeated clozapine administration differentially affects the activity of two subpopulations of midbrain dopamine neurons. Journal of Neuroscience, 5, 2525-2544.
    • (1985) Journal of Neuroscience , vol.5 , pp. 2525-2544
  • 13
    • 0027475985 scopus 로고
    • A Canadian multicenter placebo-controlled study of fixed doses of risperidone and haloperidol in the treatment of chronic schizophrenic patients
    • CHOUINARD, G., JONES, B., REMINGTON, G., et al (1993) A Canadian multicenter placebo-controlled study of fixed doses of risperidone and haloperidol in the treatment of chronic schizophrenic patients. Journal of Clinical Psychopharmacology, 13, 25-40.
    • (1993) Journal of Clinical Psychopharmacology , vol.13 , pp. 25-40
    • Chouinard, G.1    Jones, B.2    Remington, G.3
  • 15
    • 0018143206 scopus 로고
    • Neuroleptic interactions with the serotonergic-dopaminergic mechanisms in the nucleus accumbens
    • COSTALL, B. & NAYLOR, R. J. (1973) Neuroleptic interactions with the serotonergic-dopaminergic mechanisms in the nucleus accumbens. Journal of Pharmacy and Pharmacology, 30, 257-259.
    • (1973) Journal of Pharmacy and Pharmacology , vol.30 , pp. 257-259
    • Costall, B.1    Naylor, R.J.2
  • 16
    • 0017255979 scopus 로고
    • Dopamine receptor binding predicts clinical and pharmacological potencies of anti-schizophrenic drugs
    • CREESE, I., BURT, D. R. & SNYDER, S. H. (1976) Dopamine receptor binding predicts clinical and pharmacological potencies of anti-schizophrenic drugs. Science, 192, 481-483.
    • (1976) Science , vol.192 , pp. 481-483
    • Creese, I.1    Burt, D.R.2    Snyder, S.H.3
  • 17
    • 0027233552 scopus 로고
    • Behavioural effects of the putative D-3 dopamine receptor agonist 7-OH-DPAT in relation to other "D-2-like" agonists
    • DALY, S. A. & WADDINGTON, J. L. (1993) Behavioural effects of the putative D-3 dopamine receptor agonist 7-OH-DPAT in relation to other "D-2-like" agonists. Neuropharmacology, 32, 509-510.
    • (1993) Neuropharmacology , vol.32 , pp. 509-510
    • Daly, S.A.1    Waddington, J.L.2
  • 18
    • 0027490544 scopus 로고
    • 2/1C antagonist, and negative symptoms in schizophrenia: A placebo-controlled double-blind trial
    • 2/1C antagonist, and negative symptoms in schizophrenia: a placebo-controlled double-blind trial. British Journal of Psychiatry, 163, 451-454.
    • (1993) British Journal of Psychiatry , vol.163 , pp. 451-454
    • Duinkerke, S.J.1    Botter, P.A.2    Jansen, A.A.3
  • 19
    • 0026718710 scopus 로고
    • 2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine: Relation to extrapyramidal side effects
    • 2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine: relation to extrapyramidal side effects. Archives of General Psychiatry, 49, 538-544.
    • (1992) Archives of General Psychiatry , vol.49 , pp. 538-544
    • Farde, L.1    Nordstrom, A.L.2    Wiesel, F.A.3
  • 20
    • 0025094689 scopus 로고
    • Pilot clinical investigation of risperidone in the treatment of psychotic patients
    • GELDERS, Y. G., HEYLEN, S. L., VANDEN-BUSSCHE, G., et al (1990) Pilot clinical investigation of risperidone in the treatment of psychotic patients. Pharmacopsychiatry, 23, 205-211.
    • (1990) Pharmacopsychiatry , vol.23 , pp. 205-211
    • Gelders, Y.G.1    Heylen, S.L.2    Vanden-Bussche, G.3
  • 21
    • 0025869319 scopus 로고
    • An open trial of buspirone added to neuroleptics in schizophrenic patients
    • GOFF, D. C., MIDHA, K. K., BROTMAN, A. W., et al (1991) An open trial of buspirone added to neuroleptics in schizophrenic patients. Journal of Clinical Psychopharmacology, 11, 193-197.
    • (1991) Journal of Clinical Psychopharmacology , vol.11 , pp. 193-197
    • Goff, D.C.1    Midha, K.K.2    Brotman, A.W.3
  • 22
    • 0024318577 scopus 로고
    • Effects of ICI 169,369, a selective serotonin antagonist in electrophysiological tests predictive of antipsychotic activity
    • GOLDSTEIN, J. M., LITWIN, L. C., SUTTON, E. B., et al (1989) Effects of ICI 169,369, a selective serotonin antagonist in electrophysiological tests predictive of antipsychotic activity. Journal of Pharmacology and Experimental Therapeutics, 249, 673-680.
    • (1989) Journal of Pharmacology and Experimental Therapeutics , vol.249 , pp. 673-680
    • Goldstein, J.M.1    Litwin, L.C.2    Sutton, E.B.3
  • 23
    • 0027201688 scopus 로고
    • Seroquel: Electrophysiological profile of a potential atypical antipsychotic
    • _, _, _, et al (1993) Seroquel: electrophysiological profile of a potential atypical antipsychotic. Psychopharmacology, 112, 293-298.
    • (1993) Psychopharmacology , vol.112 , pp. 293-298
  • 25
    • 0025242104 scopus 로고
    • The effect of serotonergic agents on haloperidol-induced catalepsy
    • HICKS, P. B. (1990) The effect of serotonergic agents on haloperidol-induced catalepsy. Life Sciences, 47, 1609-1615.
    • (1990) Life Sciences , vol.47 , pp. 1609-1615
    • Hicks, P.B.1
  • 27
    • 0026029710 scopus 로고
    • Differential effects of repeated treatment with haloperidol and clozapine on dopamine release and metabolism in the striatum and the nucleus accumbens
    • ICHIKAWA, J. & MELTZER, H. Y. (1991) Differential effects of repeated treatment with haloperidol and clozapine on dopamine release and metabolism in the striatum and the nucleus accumbens. Journal of Pharmacology and Experimental Therapeutics, 256, 348-357.
    • (1991) Journal of Pharmacology and Experimental Therapeutics , vol.256 , pp. 348-357
    • Ichikawa, J.1    Meltzer, H.Y.2
  • 28
    • 0024828856 scopus 로고
    • The effect of clozapine and fluperlapine on the in vivo release and metabolism of dopamine in the striatum and in the frontal cortex of freely-moving rats
    • IMPERATO, A. & ANGELUCCI, L. (1989) The effect of clozapine and fluperlapine on the in vivo release and metabolism of dopamine in the striatum and in the frontal cortex of freely-moving rats. Psychopharmacology Bulletin, 25, 383-389.
    • (1989) Psychopharmacology Bulletin , vol.25 , pp. 383-389
    • Imperato, A.1    Angelucci, L.2
  • 29
    • 0027254316 scopus 로고
    • Haloperidol and clozapine treatment and their effect on m-chlorophenylpiperazine-mediated responses in schizophrenia: Implications for the mechanism of action of clozapine
    • KAHN, R. S., SIEVER, L., DAVIDSON, M., et al (1993) Haloperidol and clozapine treatment and their effect on m-chlorophenylpiperazine-mediated responses in schizophrenia: implications for the mechanism of action of clozapine. Psychopharmacology, 112 (suppl.), S90-S94.
    • (1993) Psychopharmacology , vol.112 , Issue.SUPPL.
    • Kahn, R.S.1    Siever, L.2    Davidson, M.3
  • 30
    • 0023812652 scopus 로고
    • Clozapine for the treatment-resistant schizophrenic: A double-blind comparison with chlorpromazine
    • KANE, J., HONIGFELD, G., SINGER, J., et al (1988) Clozapine for the treatment-resistant schizophrenic: a double-blind comparison with chlorpromazine. Archives of General Psychiatry, 45, 789-796.
    • (1988) Archives of General Psychiatry , vol.45 , pp. 789-796
    • Kane, J.1    Honigfeld, G.2    Singer, J.3
  • 32
    • 0024425468 scopus 로고
    • Leponex-associated granulocytopenia: A review of the situation
    • KRUPP, P. & BARNES, P. (1989) Leponex-associated granulocytopenia: a review of the situation. Psychopharmacology, 99 (suppl.), S118-S121.
    • (1989) Psychopharmacology , vol.99 , Issue.SUPPL.
    • Krupp, P.1    Barnes, P.2
  • 34
    • 0021218659 scopus 로고
    • 2) receptor numbers in the rat brain
    • 2) receptor numbers in the rat brain. Psychiatry Research, 12, 277-285.
    • (1984) Psychiatry Research , vol.12 , pp. 277-285
    • Lee, T.1    Tang, S.W.2
  • 38
  • 40
    • 0016134807 scopus 로고
    • Dopamine and the pharmacology of schizophrenia: The state of the evidence
    • MATTHYSSHE, S. (1974) Dopamine and the pharmacology of schizophrenia: the state of the evidence. Journal of Psychiatry Research, 11, 107-113.
    • (1974) Journal of Psychiatry Research , vol.11 , pp. 107-113
    • Matthysshe, S.1
  • 41
    • 0028332094 scopus 로고
    • Survey on the pharmacodynamics of the new antipsychotic risperidone
    • MEGENS, A. A. H. P., AWOUTERS, F. H. L., SCHOTTE, A., et al (1994) Survey on the pharmacodynamics of the new antipsychotic risperidone. Psychopharmacology, 114, 9-23.
    • (1994) Psychopharmacology , vol.114 , pp. 9-23
    • Megens, A.A.H.P.1    Awouters, F.H.L.2    Schotte, A.3
  • 42
    • 0011747973 scopus 로고
    • Clozapine: Clinical advantages and biological mechanisms
    • (eds S. C. Schulz & C. A. Tamminga), New York: Oxford University Press
    • MELTZER, H. Y. (1988) Clozapine: clinical advantages and biological mechanisms. In Schizophrenia: A Scientific Focus (eds S. C. Schulz & C. A. Tamminga), pp. 302-309. New York: Oxford University Press.
    • (1988) Schizophrenia: A Scientific Focus , pp. 302-309
    • Meltzer, H.Y.1
  • 43
    • 0343390079 scopus 로고
    • Clozapine: Mechanism of action in relation to its clinical advantages
    • (eds A. Kales, G. N. Stefanos & J. A. Talbott), Heidelberg: Springer-Verlag
    • _ (1990) Clozapine: mechanism of action in relation to its clinical advantages. In Recent Advances in Schizophrenia (eds A. Kales, G. N. Stefanos & J. A. Talbott), pp. 237-246. Heidelberg: Springer-Verlag.
    • (1990) Recent Advances in Schizophrenia , pp. 237-246
  • 44
    • 0003374467 scopus 로고
    • Dopaminergic and serotonergic mechanisms in the action of clozapine
    • (eds S. C. Schulz & C. A. Tamminga), New York: Raven Press
    • _ (1991a) Dopaminergic and serotonergic mechanisms in the action of clozapine. In Advances in Neuropsychiatry and Psychopharmacology. Vol. 1: Schizophrenia Research (eds S. C. Schulz & C. A. Tamminga), pp. 333-340. New York: Raven Press.
    • (1991) Advances in Neuropsychiatry and Psychopharmacology. Vol. 1: Schizophrenia Research , vol.1 , pp. 333-340
  • 45
    • 0026091799 scopus 로고
    • The mechanism of action of novel antipsychotic drugs
    • _ (1991b) The mechanism of action of novel antipsychotic drugs. Schizophrenia Bulletin, 17, 263-287.
    • (1991) Schizophrenia Bulletin , vol.17 , pp. 263-287
  • 46
    • 0026796022 scopus 로고
    • Treatment of the neuroleptic-nonresponsive schizophrenic patient
    • _ (1992) Treatment of the neuroleptic-nonresponsive schizophrenic patient. Schizophrenia Bulletin, 18, 515-542.
    • (1992) Schizophrenia Bulletin , vol.18 , pp. 515-542
  • 47
    • 0001484404 scopus 로고
    • The concept of atypical antipsychotics
    • (eds J. A. den Boer, H. G. M. Westenberg & H. M. van Pragg), Chichester: Wiley
    • _ (1995) The concept of atypical antipsychotics. In Advances in the Neurobiology of Schizophrenia (eds J. A. den Boer, H. G. M. Westenberg & H. M. van Pragg), pp. 265-273. Chichester: Wiley.
    • (1995) Advances in the Neurobiology of Schizophrenia , pp. 265-273
  • 49
    • 0026357347 scopus 로고
    • Effects of antipsychotic drugs on serotonin receptors
    • _ & NASH, J. F. (1991) Effects of antipsychotic drugs on serotonin receptors. Pharmacology Reviews, 43, 587-604.
    • (1991) Pharmacology Reviews , vol.43 , pp. 587-604
    • Nash, J.F.1
  • 51
    • 0027208863 scopus 로고
    • The cimetidine-induced increase in prolactin secretion in schizophrenia: Effect of clozapine
    • _, MAES, M. & LEE, M. A. (1993) The cimetidine-induced increase in prolactin secretion in schizophrenia: effect of clozapine. Psychopharmacology, 112 (suppl.), S95-S104.
    • (1993) Psychopharmacology , vol.112 , Issue.SUPPL.
    • Maes, M.1    Lee, M.A.2
  • 52
    • 0028273759 scopus 로고
    • Effect of scopolamine on the efflux of dopamine and its metabolites following clozapine, haloperidol or thioridazine
    • _, CHAI, B. L., THOMPSON, P. A., et al (1994) Effect of scopolamine on the efflux of dopamine and its metabolites following clozapine, haloperidol or thioridazine. Journal of Pharmacology and Experimental Therapeutics, 268, 1452-1461.
    • (1994) Journal of Pharmacology and Experimental Therapeutics , vol.268 , pp. 1452-1461
    • Chai, B.L.1    Thompson, P.A.2
  • 53
    • 0002926873 scopus 로고
    • The mechanism of action of atypical antipsychotic drugs: An update
    • (eds S. J. Watson & H. Akil), New York: Raven Press
    • _, YAMAMOTO, B. K., LOWY, M. T., et al (1995) The mechanism of action of atypical antipsychotic drugs: an update. In Biology of Schizophrenia and Affective Disease- ARNMD Series (eds S. J. Watson & H. Akil), pp. 451-492. New York: Raven Press.
    • (1995) Biology of Schizophrenia and Affective Disease- ARNMD Series , pp. 451-492
    • Yamamoto, B.K.1    Lowy, M.T.2
  • 54
    • 0027218797 scopus 로고
    • Seroquel: Behavioral effects in conventional and novel tests for atypical antipsychotic drug
    • MIGLER, B. M., WARAWA, E. J. & MALIK, J. B. (1993) Seroquel: Behavioral effects in conventional and novel tests for atypical antipsychotic drug. Psychopharmacology, 112, 299-307.
    • (1993) Psychopharmacology , vol.112 , pp. 299-307
    • Migler, B.M.1    Warawa, E.J.2    Malik, J.B.3
  • 56
    • 0025239750 scopus 로고
    • Acute effects of typical and atypical antipsychotic drugs on the release of dopamine from prefrontal cortex, nucleus accumbens, and striatum of the rat: An in vivo microdialysis study
    • MOGHADDAM, B. & BUNNEY, B. S. (1990) Acute effects of typical and atypical antipsychotic drugs on the release of dopamine from prefrontal cortex, nucleus accumbens, and striatum of the rat: an in vivo microdialysis study. Journal of Neurochemistry, 54, 1775-1760.
    • (1990) Journal of Neurochemistry , vol.54 , pp. 1775-11760
    • Moghaddam, B.1    Bunney, B.S.2
  • 58
    • 0027481384 scopus 로고
    • Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs
    • MONSMA, F. J., JR, SHEN, Y., WARD, R. R., et al (1993) Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs. Molecular Pharmacology, 43, 320-327.
    • (1993) Molecular Pharmacology , vol.43 , pp. 320-327
    • Monsma Jr., F.J.1    Shen, Y.2    Ward, R.R.3
  • 59
    • 0025695028 scopus 로고
    • Ketanserin pretreatment attenuates NDMA-induced dopamine release in the striatum as measured by in vivo microdialysis
    • NASH, J. F. (1990) Ketanserin pretreatment attenuates NDMA-induced dopamine release in the striatum as measured by in vivo microdialysis. Life Sciences, 47, 2402-2408
    • (1990) Life Sciences , vol.47 , pp. 2402-2408
    • Nash, J.F.1
  • 61
    • 0025167982 scopus 로고
    • Chronic treatment with clozapine or haloperidol differentially regulates dopamine and serontonin receptor in rat brain
    • O'DELL, S., LA HOSTE, G. J., WIDWARK, C. B., et al (1990) Chronic treatment with clozapine or haloperidol differentially regulates dopamine and serontonin receptor in rat brain. Synapse, 6, 146-153.
    • (1990) Synapse , vol.6 , pp. 146-153
    • O'Dell, S.1    La Hoste, G.J.2    Widwark, C.B.3
  • 62
    • 0027165890 scopus 로고
    • Effect of clozapine and fluphenazine treatment on responses to m-chlorophenylpiperazine infusions in schizophrenia
    • OWENS, R. R., JR, GUTIERREZ-ESTEINOU, R., HSAIO, J., et al (1993) Effect of clozapine and fluphenazine treatment on responses to m-chlorophenylpiperazine infusions in schizophrenia. Archives of General Psychiatry, 50, 636-644.
    • (1993) Archives of General Psychiatry , vol.50 , pp. 636-644
    • Owens Jr., R.R.1    Gutierrez-Esteinou, R.2    Hsaio, J.3
  • 63
    • 1842286609 scopus 로고
    • The effects of clozapine on dopamine, 5-HT and glutamate release in the rat medial prefrontal cortex
    • PEHEK, E. A., YAMAMOTO, B. K. & MELTZER, H. Y. (1991) The effects of clozapine on dopamine, 5-HT and glutamate release in the rat medial prefrontal cortex. Schizophrenia Research, 4, 324.
    • (1991) Schizophrenia Research , vol.4 , pp. 324
    • Pehek, E.A.1    Yamamoto, B.K.2    Meltzer, H.Y.3
  • 64
    • 0025869230 scopus 로고
    • Clozapine attenuates n-methyl-D-aspartate receptor complex-mediated responses in vivo: Tentative evidence for a functional modulation by a noradrenergic mechanism
    • RAO, T. S., CONTRERAS, P. C., CLER, J. A., et al (1991) Clozapine attenuates n-methyl-D-aspartate receptor complex-mediated responses in vivo: tentative evidence for a functional modulation by a noradrenergic mechanism. Neuropharmacology, 30, 557-565.
    • (1991) Neuropharmacology , vol.30 , pp. 557-565
    • Rao, T.S.1    Contreras, P.C.2    Cler, J.A.3
  • 69
    • 0027248858 scopus 로고
    • Seroquel: Biochemical profile of a potential atypical antipsychotic
    • SALLER, C. F. & SALAMA, A. I. (1993) Seroquel: biochemical profile of a potential atypical antipsychotic. Psychopharmacology, 112, 285-292.
    • (1993) Psychopharmacology , vol.112 , pp. 285-292
    • Saller, C.F.1    Salama, A.I.2
  • 71
    • 85088548479 scopus 로고
    • 2 antagonists stereoselectively prevent the neurotoxicity of 3,4-methylenedioxymethamphetamine
    • 2 antagonists stereoselectively prevent the neurotoxicity of 3,4-methylenedioxymethamphetamine. European Journal of Pharmacology, 223, 65-74.
    • (1991) European Journal of Pharmacology , vol.223 , pp. 65-74
    • Taylor, V.L.1    Abbate, G.M.2
  • 72
    • 0026613672 scopus 로고
    • 2 receptors exert a state dependent regulation of dopaminergic function: Studies with MDL 100,907 and the amphetamine analogue, 3,4-methylenedioxymethamphetamine
    • 2 receptors exert a state dependent regulation of dopaminergic function: studies with MDL 100,907 and the amphetamine analogue, 3,4-methylenedioxymethamphetamine. European Journal of Pharmacology, 223, 65-74.
    • (1992) European Journal of Pharmacology , vol.223 , pp. 65-74
    • Fadayel, G.1    Sullivan, C.K.2
  • 73
    • 0024441791 scopus 로고
    • Receptor occupancy by ritanserin and risperidone measured using ex vivo radiography
    • SCHOTTE, AS., DE BRUYCKERE, K., JANSSEN, P. F., et al (1989) Receptor occupancy by ritanserin and risperidone measured using ex vivo radiography. Brain Research, 500, 295-301.
    • (1989) Brain Research , vol.500 , pp. 295-301
    • Schotte, A.S.1    De Bruyckere, K.2    Janssen, P.F.3
  • 74
    • 0016592484 scopus 로고
    • Antipsychotic drugs: Direct correlation between clinical potency and presynaptic action on dopamine neurons
    • SEEMAN, P. & LEE, T. (1975) Antipsychotic drugs: direct correlation between clinical potency and presynaptic action on dopamine neurons. Science, 188, 1217-1219.
    • (1975) Science , vol.188 , pp. 1217-1219
    • Seeman, P.1    Lee, T.2
  • 75
    • 0027282204 scopus 로고
    • Molecular cloning and expression of a 5-hydroxytryptamine serotonin receptor subtype
    • SHEN, Y., MONSMA, F. J., JR, METCALF, M. A., et al (1993) Molecular cloning and expression of a 5-hydroxytryptamine serotonin receptor subtype. Journal of Biology and Chemistry, 268, 18200-18204.
    • (1993) Journal of Biology and Chemistry , vol.268 , pp. 18200-18204
    • Shen, Y.1    Monsma Jr., F.J.2    Metcalf, M.A.3
  • 76
    • 0025050445 scopus 로고
    • Sertindole, a new neuroleptic with extreme selectivity on AlO versus A9 dopamine neurons in the rat
    • SKARSFELDT, T. & PERREGARD, J. (1990) Sertindole, a new neuroleptic with extreme selectivity on AlO versus A9 dopamine neurons in the rat. European Journal of Pharmacology, 182, 613-614.
    • (1990) European Journal of Pharmacology , vol.182 , pp. 613-614
    • Skarsfeldt, T.1    Perregard, J.2
  • 78
    • 0027340586 scopus 로고
    • 2 receptor antagonist MDL 100907 as a putative atypical antipsychotic: Behavioral, electrophysiological and neurochemical studies
    • 2 receptor antagonist MDL 100907 as a putative atypical antipsychotic: behavioral, electrophysiological and neurochemical studies. Journal of Pharmacology and Experimental Therapeutics, 266, 684-691.
    • (1993) Journal of Pharmacology and Experimental Therapeutics , vol.266 , pp. 684-691
    • Kehne, J.H.1    Fadayel, G.M.2
  • 79
    • 0027887319 scopus 로고
    • Characterization of typical and atypical antipsychotic drugs based on in vivo occupancy serotonin-2 and dopamine-2 receptors
    • STOCKMEIER, C. A., DICARLO, J. J., ZHANG, Y., et al (1993) Characterization of typical and atypical antipsychotic drugs based on in vivo occupancy serotonin-2 and dopamine-2 receptors. Journal of Pharmacology and Experimental Therapeutics, 266, 1374-1384.
    • (1993) Journal of Pharmacology and Experimental Therapeutics , vol.266 , pp. 1374-1384
    • Stockmeier, C.A.1    Dicarlo, J.J.2    Zhang, Y.3
  • 81
    • 0024478415 scopus 로고
    • 2 receptor antagonist, activates midbrain dopamine neurons by blocking serotonergic inhibition
    • 2 receptor antagonist, activates midbrain dopamine neurons by blocking serotonergic inhibition. Psychopharmacology, 98, 45-50.
    • (1989) Psychopharmacology , vol.98 , pp. 45-50
    • Ugedo, L.1    Grenhoff, J.2    Svensson, T.H.3
  • 82
    • 0026427253 scopus 로고
    • 4 receptor with high affinity for the antipsychotic clozapine
    • 4 receptor with high affinity for the antipsychotic clozapine. Nature, 350, 610-614.
    • (1991) Nature , vol.350 , pp. 610-614
    • Van Tol, H.H.1    Bunzow, J.R.2    Guan, H.-E.3
  • 84
    • 0027466856 scopus 로고
    • Potency mismatch for behavioral and biochemical effects by dopamine receptor antagonist: Implications for the mechanism of action of clozapine
    • WADENBERG, M. L., AHLEWNIUS, S. & SVENSSON, T. H. (1993) Potency mismatch for behavioral and biochemical effects by dopamine receptor antagonist: implications for the mechanism of action of clozapine. Psychopharmacology, 110, 273-279.
    • (1993) Psychopharmacology , vol.110 , pp. 273-279
    • Wadenberg, M.L.1    Ahlewnius, S.2    Svensson, T.H.3
  • 87
    • 0020694390 scopus 로고
    • Comparison of the effects of chronic haloperidol treatment on A9 and A10 dopamine neurons in the rat
    • WHITE, F. J. & WANG, R. Y. (1983) Comparison of the effects of chronic haloperidol treatment on A9 and A10 dopamine neurons in the rat. Life Sciences, 32, 983-993.
    • (1983) Life Sciences , vol.32 , pp. 983-993
    • White, F.J.1    Wang, R.Y.2
  • 88
    • 0028358082 scopus 로고
    • An open clinical and biochemical study of ritanserin in acute patients with schizophrenia
    • WIESEL, F. A,. NORDSTRÖM, A.-L., FARDE, L., et al (1994) An open clinical and biochemical study of ritanserin in acute patients with schizophrenia. Psychopharmacology, 114, 31-38.
    • (1994) Psychopharmacology , vol.114 , pp. 31-38
    • Wiesel, F.A.1    Nordström, A.-L.2    Farde, L.3
  • 89
    • 0026495282 scopus 로고
    • Serotonergic drugs do not substitute for clozapine in clozapine-trained rats in a two-lever drug discrimination procedure
    • WILEY, J. L. & PORTER, J. H. (1992) Serotonergic drugs do not substitute for clozapine in clozapine-trained rats in a two-lever drug discrimination procedure. Pharmacology, Biochemistry and Behavior, 43, 961-965.
    • (1992) Pharmacology, Biochemistry and Behavior , vol.43 , pp. 961-965
    • Wiley, J.L.1    Porter, J.H.2
  • 91
    • 8944248522 scopus 로고
    • Effect of chronic antipsychotic treatment of extracellular dopamine and glutamate concentrations in the rat striatum
    • YAMAMOTO, B. K. & COOPERMAN, M. A. (1992) Effect of chronic antipsychotic treatment of extracellular dopamine and glutamate concentrations in the rat striatum. Society of Neuroscience Abstracts, 18, 379.
    • (1992) Society of Neuroscience Abstracts , vol.18 , pp. 379
    • Yamamoto, B.K.1    Cooperman, M.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.