Tuning the equilibrium ion affinity and selectivity of the EF-hand calcium binding motif: Substitutions at the gateway position

Biochemistry

Volumn 35, Issue 21, 1996, Pages 6697-6705

  Drake, Steven K ^a   Lee, Keith L ^a   Falke, Joseph J ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CALCIUM BINDING; CALCIUM CELL LEVEL; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; ELECTROSTATIC PRECIPITATION; EQUILIBRIUM CONSTANT; ION TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING;

BINDING SITES; CALCIUM; CALCIUM-BINDING PROTEINS; CARRIER PROTEINS; COMPUTER GRAPHICS; ESCHERICHIA COLI; GALACTOSE; GENETIC ENGINEERING; KINETICS; METALS; MODELS, MOLECULAR; MONOSACCHARIDE TRANSPORT PROTEINS; MUTAGENESIS, SITE-DIRECTED; PERIPLASMIC BINDING PROTEINS; POINT MUTATION; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; REPRODUCIBILITY OF RESULTS; THERMODYNAMICS;

ESCHERICHIA COLI;

EID: 0029954447     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi952430l     Document Type: Article

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