Sodium polystyrene sulfonate treatment for lithium toxicity: Effects on serum potassium concentrations

Academic Emergency Medicine

Volumn 3, Issue 4, 1996, Pages 333-337

  Linakis, J G ^a   Hull, K M ^a   Lacouture, P G ^a   Lockhart, G R ^a   Lewander, W J ^a   Maher, T J ^a  

^a RHODE ISLAND HOSPITAL   (United States)

Author keywords

cation exchange resins; lithium; mice; poisoning; potassium; toxicology

Indexed keywords

LITHIUM; POLYSTYRENESULFONATE SODIUM;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG EFFICACY; DRUG OVERDOSE; HYPOKALEMIA; MALE; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; POTASSIUM BLOOD LEVEL; PRIORITY JOURNAL;

EID: 0029953978     PISSN: 10696563     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1553-2712.1996.tb03446.x     Document Type: Article

References (18)

1. 1 Simard M, Gumbiner B, Lee A, Lewis H, Norman D. Lithium carbonate intoxication: a case report and review of the literature. Arch Intern Med. 1989 ; 149: 36–46.
2. 2 Favin FD, Oderda GM, Klein–Schwartz W, Rose SR. In vitro study of lithium carbonate adsorption by activated charcoal. J Toxicol Clin Toxicol. 1988 ; 26: 443–50.
3. 3 Smith SW, Ling LJ, Halstenson CE. Whole–bowel irrigation as a treatment for acute lithium overdose. Ann Emerg Med. 1991 ; 20: 536–9.
4. 4 Gehrke J, Gehrke CW. In vitro binding of lithium ion using a clinical cation exchange resin (Kayexalate) [abstract]. Ann Emerg Med. 1986 ; 15: 651.
5. 5 Welch DW, Driscoll JL, Lewander WJ, Johnson PN. In vitro lithium binding with sodium polystyrene sulfonate [abstract]. Vet Hum Toxicol. 1987 ; 29: 472.
6. 6 Linakis JG, Lacouture PG, Eisenberg MS, et al. Administration of activated charcoal or sodium polystyrene sulfonate (Kayexalate) as gastric decontamination for lithium intoxication: an animal model. Pharmacol. Toxicol. 1989 ; 65: 387–9.
7. 7 Linakis JG, Eisenberg MS, Lacouture PG, et al. Multiple dose sodium polystyrene sulfonate in lithium intoxication: an animal model. Pharmacol. Toxicol. 1992 ; 70: 38–40.
8. 8 Linakis J, Hull K, Lee C, Maher T, Lewander W, Lacouture P. Effect of delayed treatment with sodium polystyrene sulfonate on serum lithium concentrations in mice. Acad Emerg Med. 1995 ; 2: 681–5.
9. 9 Linakis JG, Hull KM, Lacouture PG, Lewander WJ, Maher T. Multiple dose sodium polystyrene sulfonate (SPS) enhances the elimination of intravenously administered lithium [abstract]. Pharmacologist. 1990 ; 32: 149.
10. 10 Roberge RJ, Martin TG, Schneider SM. Use of sodium polystyrene sulfonate in a lithium overdose. Ann Emerg Med. 1993 ; 22: 1911–5.
11. 11 Gilman AG, Goodman LS, Rail TW, Murad F (eds). The Pharmacological Basis of Therapeutics. New York: Macmillan Publishing, 1985, p 429.
12. 12 Jefferson JW. Potassium supplementation in lithium patients: a timely intervention or premature speculation J Clin Psychiatry. 1992 ; 53: 370–2.
13. 13 Klaassen CD, Amdur MO, Doull J (eds). Casarett and Doull's Toxicology. The Basic Science of Poisons, 3rd edition. New York: Macmillan Publishing, 1986, p 621.
14. 14 Everett RM, Steadman, DH Jr. Clinical biochemistry. In: Foster H, Small J, Fox J (eds). The Mouse in Biomedical Research. Volume 3: Normative Biology, Immunology and Husbandry. Boston: Academic Press, 1983, p 41.
15. 15 Winchester JF. Lithium. In: Haddad L, Winchester J (eds). Clinical Management of Poisoning and Drug Overdose. Second edition. Philadelphia: W. B. Saunders, 1990, pp 656–65.
16. 16 Shannon MW, Eisen TF, Linakis JG, Woolf AD. Clinical features of acute versus chronic lithium intoxication [abstract]. Vet Hum Toxicol. 1989 ; 31: 370.
17. 17 Belanger DR, Tierne MG, Dickinson G. Effect of sodium polystyrene sulfonate on lithium availability. Ann Emerg Med. 1992 ; 21: 1312–5.
18. 18 Tomaszewski C, Musso C, Pearson JR, Kulig K, Marx A. Lithium absorption prevented by sodium polystyrene sulfonate in volunteers. Ann Emerg Med. 1992 ; 21: 1308–11.