Endoplasmic reticulum localization of Sec12p is achieved by two mechanisms: Rer1p-dependent retrieval that requires the transmembrane domain and Rer1p-independent retention that involves the cytoplasmic domain

Journal of Cell Biology

Volumn 134, Issue 2, 1996, Pages 279-293

  Sato, Miyuki ^a   Sato, Ken ^a   Nakano, Akihiko ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MANNOSE; MEMBRANE PROTEIN;

ARTICLE; CELL MEMBRANE TRANSPORT; CYTOPLASM; ENDOPLASMIC RETICULUM; GOLGI COMPLEX; MEMBRANE VESICLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN TRANSPORT; SACCHAROMYCES CEREVISIAE; YEAST;

AMINO ACID SEQUENCE; BASE SEQUENCE; BINDING SITES; CLONING, MOLECULAR; CYTOPLASM; DIPEPTIDYL PEPTIDASES; DNA, FUNGAL; ENDOPLASMIC RETICULUM; FUNGAL PROTEINS; MANNOSE; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN SORTING SIGNALS; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 0029953563     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.134.2.279     Document Type: Article

References (50)

1. Balch, W.E., J.M. McCaffery, H. Plutner, and M.G. Farquhar. 1994. Vesicular stomatitis virus glycoprotein is sorted and concentrated during export from the endoplasmic reticulum. Cell. 76:841-852.
2. Barlowe, C., and R. Schekman. 1993. SEC12 encodes a guanine nucleotide exchange factor essential for transport vesicle budding from the ER. Nature (Lond.). 365:347-349.
3. Barlowe, C., L. Orci, M.H. Yeung, S. Hamamoto, N. Salama, M.F. Rexach, M. Ravazzola, M. Amherdt, and R. Schekman. 1994. COPII: a membrane coat formed by Sec proteins that drive vesicles budding from the endoplasmic reticulum Cell. 77:895-907.
4. Boehm, J., H.D. Ulrich, R. Ossig, and H.D. Schmitt. 1994. Kex2-dependent invertase secretion as a tool to study the targeting of transmembrane proteins which are involved in ER→Golgi transport in yeast. EMBO (Eur. Mol. Biol. Organ.) J. 13:3696-3710.
5. Bretscher, M.S., and S. Munro. 1993. Cholesterol and the Golgi apparatus. Science. (Wash. DC). 261:1280-1281.
6. Bullock, W.O., J.M. Fernandez, and J.M. Short. 1987. XL1-blue: a high efficiency plasmid transforming recA Escherichia coli strain with beta-galactosidase selection. Biotechniques. 5:376.
7. Cosson, P., and F. Letourneur. 1994. Coatomer interaction with dilysine endoplasmic reticulum retention motifs. Science (Wash. DC). 263:1629-1631.
8. Dean, N., and H.R.B. Pelham. 1990. Recycling of proteins from the Golgi compartment to the ER in yeast. J. Cell Biol. 111:369-377.
9. d'Enfert, C., C. Barlowe, S. Nishikawa, A. Nakano, and R. Schekman. 1991. Structural and functional dissection of a membrane glycoprotein required for vesicle budding from the endoplasmic reticulum. Mol. Cell. Biol. 11: 5727-5734.
10. Gaynor, E.C., S. te Heesen, T.R. Graham, M. Aebi, and S.D. Emr. 1994. Signal-mediated retrieval of a membrane protein from the Golgi to the ER in yeast. J. Cell Biol. 127:653-665.
11. Gimeno, R.E., P. Espenshade, and C. Kaiser. 1995. SED4 encodes a yeast endoplasmic reticulum protein that binds Sec16p and participates in vesicle formation. J. Cell Biol. 131:325-338.
12. Graham, T.R., and V.A. Krasnov. 1995. Sorting of α1,3-mannosyltransferase is mediated by a lumenal domain interaction, and a transmembrane domain signal that can confer clathrin-dependent Golgi localization to a secreted protein. Mol. Biol. Cell. 6:809-824.
13. Graham, T.R., M. Seeger, G.S. Payne, V.L. MacKay, and S.D. Emr. 1994. Clathrin-dependent localization of α1,3-mannosyltransferase to the Golgi complex of Saccharomyces cerevisiae. J. Cell Biol. 127:667-678.
14. Hardwick, K.G., J.C. Boothroyd, A.D. Rudner, and H.R.B. Pelham. 1992. Genes that allow yeast cells to grow in the absence of the HDEL receptor. EMBO (Eur. Mol. Biol. Organ.) J. 11:4187-4195.
15. Hsu, V.W., L.C. Yuan, J.G. Nuchtern, J. Lippincott-Schwartz, G.J. Hammerling, and R.D. Klausner. 1991. A recycling pathway between the endoplasmic reticulum and the Golgi apparatus for retention of unassembled MHC class I molecule. Nature (Lond.). 352:441-444.
16. Itin, C., R. Schindler, and H.P. Hauri. 1995. Targeting of protein ERGIG-53 to the ER/ERGIC/cis-Golgi recycling pathway. J. Cell Biol. 131:57-67.
17. Jackson, M.R., T. Nillson, and P.A. Peterson. 1990. Identification of a consensus motif for retention of transmembrane proteins in the endoplasmic reticulum. EMBO (Eur. Mol. Biol. Organ.) J. 9:3153-3162.
18. Jackson, M.R., T. Nillson, and P.A. Peterson. 1993. Retrieval of transmembrane proteins to the endoplasmic reticulum. J. Cell Biol. 121:317-333.
19. Keszenman-Pereyra, D., and K. Hieda. 1988. A colony procedure for transformation of Saccharomyces cerevisiae. Curr. Genet. 13:21-23.
20. Letourneur, F., E.C. Gaynor, S. Hennecke, C. Démollière, R. Duden, S.D. Emr, H. Riezman, and P. Cosson. 1994. Coatomer is essential for retrieval of dilysine-tagged proteins to the endoplasmic reticulum. Cell. 79:1199-1207.
21. Lewis, M.J., and H.R.B. Pelham. 1990. A human homologue of the yeast HDEL receptor. Nature (Lond.). 348:162-163.
22. Lewis, M.J., and H.R.B. Pelham. 1992. Ligand induced redistribution of a human KDEL receptor from the Golgi complex to the endoplasmic reticulum. Cell. 68:353-364.
23. Lodish, H.F. 1988. Transport of secretory and membrane glycoproteins from the rough endoplasmic reticulum to the Golgi. A rate-limiting step in protein maturation and secretion. J. Biol. Chem. 263:2107-2110.
24. Mizuno, M., and S.J. Singer. 1993. A soluble secretory protein is first concentrated in the endoplasmic reticulum before transfer to the Golgi apparatus. Proc. Natl. Acad. Sci. USA. 90:5732-5736.
25. Munro, S., and H.R.B. Pelham. 1987. A C-terminal signal prevents secretion of luminal ER proteins. Cell. 48:899-907.
26. Munro, S. 1995. An investigation of the role of transmembrane domains in Golgi protein retention. EMBO (Eur. Mol. Biol. Organ.) J. 14:4695-4704.
27. Nakano, A., and M. Muramatsu. 1989. A novel GTP-binding protein, SAR1, is involved in transport from the endoplasmic reticulum to the Golgi apparatus. J. Cell Biol. 109:2677-2691.
28. Nakano, A., D. Brada, and R. Schekman. 1988. A membrane glycoprotein, Sec12p, required for protein transport from the endoplasmic reticulum to the Golgi apparatus in yeast. J. Cell Biol. 107:851-863.
29. Nakayama, K., T. Nagasu, Y. Shimma, J. Kuromitsu, and Y. Jigami. 1992. OCHI encodes a novel membrane bound mannosyltransferase: outer chain elongation of asparagine-linked oligosaccharides. EMBO (Eur. Mol. Biol. Organ.) J. 11:2511-2519.
30. Nilsson, T., M.H. Hoe, P. Slusarewicz, C. Rabouille, R. Watson, F. Hunte, G. Watzele, E.G. Berger, and G. Warren. 1993. Kin recognition between medial Golgi enzymes in HeLa cells. EMBO (Eur. Mol. Biol. Organ.) J. 13:562-574.
31. Nishikawa, S., and A. Nakano. 1991. The GTP-binding Sar1 protein is localized to the early compartment of the yeast secretory pathway. Biochim. Biophys. Acta. 103:135-143.
32. Nishikawa, S., and A. Nakano. 1993. Identification of a gene required for membrane protein retention in the early secretory pathway. Proc. Natl. Acad. Sci. USA. 90:8179-8183.
33. Nishikawa, S., N. Umemoto, Y. Ohsumi, A. Nakano, and Y. Anraku. 1990. Biogenesis of vacuolar membrane glycoproteins of yeast Saccharomyces cerevisiae. J. Biol. Chem. 265:7440-7448.
34. Nishikawa, S., A. Hirata, and A. Nakano. 1994. Inhibition of endoplasmic reticulum (ER)-to-Golgi transport induces relocalization of binding protein (BiP) within the ER to form the BiP bodies. Mol. Biol. Cell. 5:1129-1143.
35. Oka, T., and A. Nakano. 1994. Inhibition of GTP hydrolysis by Sarlp causes accumulation of vesicles that are a functional intermediate of the ER-to-Golgi transport in yeast. J. Cell Biol. 124:425-434.
36. Pelham, H.R.B. 1988. Evidence that luminal ER proteins are sorted from secreted proteins in a post-ER compartment. EMBO (Eur. Mol. Biol. Organ.) J. 7:913-918.
37. Pelham, H.R.B., K.G. Hardwick, and M.J. Lewis. 1988. Sorting of soluble ER proteins in yeast. EMBO (Eur. Mol. Biol. Organ.) J. 7:1757-1762.
38. Qadota, H., I. Ishii, A. Fujiyama, Y. Ohya, and Y. Anraku. 1992. RHO gene products, putative small GTP-binding proteins, are important for activation of the CALI/CDC43 gene product, a protein geranylgeranyltransferase in Saccharomyces cerevisiae. Yeast. 8:735-741.
39. Rexach, M.F., and R. Schekman. 1991. Distinct biochemical requirements for the budding, targeting, and fusion of ER-derived transport vesicles. J. Cell Biol. 114:219-229.
40. Roberts, C.J., G. Pohling, J.H. Royhman, and T.H. Stevens. 1989. Structure, biosynthesis, and localization of dipeptidyl aminopeptidase B, an integral membrane glycoprotein of the yeast vacuole. J. Cell Biol. 108:1363-1373.
41. Roberts, C.J., F.N. Stevens, and T.H. Stevens. 1992. Membrane protein sorting in the yeast secretory pathway: evidence that the vacuole may be the default compartment. J. Cell Biol. 119:69-83.
42. Sambrook, J., E.F. Fritsch, and T. Maniatis. 1989. Molecular Cloning, A Laboratory Manual, 2nd Ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
43. Sato, K., S. Nishikawa, and A. Nakano. 1995. Membrane protein retrieval from the Golgi apparatus to the endoplasmic reticulum (ER): characterization of the RERI gene products as a component involved in ER localization of Sec12p. Mol. Biol. Cell. 6:1459-1477.
44. 2-terminal double-arginine motif maintains type II membrane proteins in the endoplasmic reticulum. EMBO (Eur. Mol. Biol. Organ.) J. 13:1696-1705.
45. Semenza, J.C., K.G. Hardwick, N. Dean, and H.R.B. Pelham. 1990. ERD2, a yeast gene required for the receptor-mediated retrieval of luminal ER proteins from the secretory pathway. Cell. 61:1349-1357.
46. Sweet, D.J., and H.R.B. Pelham. 1992. The Saccharomyces cerevisiae SEC20 gene encodes a membrane glycoprotein which is sorted by the HDEL retrieval system. EMBO (Eur. Mol. Biol. Organ.) J. 11:423-432.
47. Swift, A.M., and C.E. Machamer. 1991. A Golgi retention signal in a membrane-spanning domain of coronavirus E1 protein. J. Cell Biol. 115:19-30.
48. 2-terminal transmembrane domains of cytochrome P450 contain independent signals for retention in the endoplasmic reticulum. J. Biol. Chem. 270:24327-24333.
49. Weisz, O.A., A.M. Swift, and C.E. Machamer. 1993. Oligomerization of a membrane protein correlates with its retention in the Golgi complex. J. Cell Biol. 122:1185-1196.
50. Yoshikawa, A., and K. Isono. 1990. Chromosome III of Saccharomyces cerevisiae: an ordered clone bank, a detailed restriction map and analysis of transcripts suggest the presence of 160 genes. Yeast. 6:383-401.