Natural history and risk factors for thrombosis in 360 patients with antiphospholipid antibodies: A four-year prospective study from the Italian registry

American Journal of Medicine

Volumn 100, Issue 5, 1996, Pages 530-536

  Finazzi, Guido ^a   Brancaccio, Vincenzo ^b   Moia, Marco ^c   Ciavarella, Nicola ^d   Mazzucconi, M Gabriella ^e   Schinco, PierCarla ^f   Ruggeri, Marco ^g   Pogliani, Enrico M ^h   Gamba, Gabriella ⁱ   Rossi, Edoardo ^j   Baudo, Francesco ^k   Manotti, Cesare ^l   D'Angelo, Armando ^m   Palareti, Gualtiero ⁿ   De Stefano, Valerio ^o   Berrettini, Mauro ^p   Barbui, Tiziano ^a  

^a OSPEDALI RIUNITI   (Italy)

^b CARDARELLI HOSPITAL   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

^d UNIVERSITY OF BARI   (Italy)

^e SAPIENZA UNIVERSITY OF ROME   (Italy)

^f UNIVERSITY OF TURIN   (Italy)

^g SAN BORTOLO HOSPITAL   (Italy)

^h SAN GERARDO HOSPITAL   (Italy)

ⁱ UNIVERSITY OF PAVIA   (Italy)

^j UNIVERSITY OF MILAN   (Italy)

^k OSPEDALE NIGUARDA CA GRANDA   (Italy)

^l Ospedale Regionale   (Italy)

^m SAN RAFFAELE HOSPITAL   (Italy)

ⁿ UNIVERSITY OF BOLOGNA   (Italy)

^o CATHOLIC UNIVERSITY   (Italy)

^p UNIVERSITY OF PERUGIA   (Italy)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOLIPIN ANTIBODY; IMMUNOGLOBULIN G; LUPUS ANTICOAGULANT; PHOSPHOLIPID ANTIBODY;

ADOLESCENT; ADULT; AGED; ANTIBODY TITER; ARTICLE; BLOOD VESSEL OCCLUSION; CAUSE OF DEATH; CHILD; COHORT ANALYSIS; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; NONHODGKIN LYMPHOMA; PREGNANCY COMPLICATION; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK FACTOR; SPONTANEOUS ABORTION; THROMBOSIS;

EID: 0029953246     PISSN: 00029343     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9343(96)00060-5     Document Type: Article

References (38)

1. Harris EN, Gharavi AE, Boey ML, et al. Anticardiolipin antibodies: detection by radioimmunoassay and association with thrombosis in systemic lupus erythematosus. Lancef. 1983;ii:1211-1214.
2. Galli M, Comfurius P, Massen C, et al. Anticardiolipin antibodies (ACA) directed not to cardiolipin but to a plasma protein cofactor. Lancet. 1990;335:1544-1547.
3. McNeil HP, Simpson RJ, Chesterman CN, Krilis SA. Antiphospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: b2-glycoprotein I (Apolipoprotein H). Proc Natl Acad Sci USA. 1990;87:4120-4124.
4. Bevers EM, Galli M, Barbui T, et al. Lupus anticoagulant IgG's (LA) are not directed to phospholipids only, but to a complex of lipid-bound human prothrombin. Thromb Haemostas. 1991;66:629-632.
5. Arvieux J, Roussel B, Jacob MC, Colomb MG. Measurement of anti-phospholipid antibodies by ELISA using b2-glycoprotein I as an antigen. J Immunol Meth. 1991;143:223-229.
6. Loizou S, McCrea JD, Rudge AC, et al. Measurement of anticardiolipin antibodies by an enzyme-linked immunosorbent assay: standardization and quantitation of results. Clin Exp Immunol. 1986;62:739-744.
7. Triplett DA. Assays for detection of antiphospholipid antibodies. Lupus. 1994;3:281-287.
8. Love PE, Santoro SA. Antiphospholipid antibodies: anticardiolipin and the lupus anticoagulant in the systemic lupus erythematosus (SLE) and in non-SLE disorders. Ann Intern Med, 1990;112:682-698.
9. Vila P, Hernandez MC, Lopez-Fernandez MF, Battle J. Prevalence, follow-up and clinical significance of the anticardiolipin antibodies in normal subjects. Thromb Haemostas. 1994;72:209-213.
10. Hughes GRV. The antiphospholipid syndrome: ten years on. Lancet. 1993;342:341-344.
11. Long AA, Ginsberg JS, Brill-Edwards, et al. The relationship of antiphospholipid antibodies to thromboembolic disease in systemic lupus erythematosus: a cross-sectional study. Thromb Haemostas. 1991;66:520-524.
12. Ginsberg JS, Brill-Edwards P, Johnston M, et al. Relationship of antiphospholipid antibodies to pregnancy loss in patients with systemic lupus erythematosus: a cross-sectional study. Blood. 1992;80:975-980.
13. Barbui T, Finazzi G. Clinical trials on antiphospholipid syndrome: what is being done and what is needed? Lupus. 1994;3:303-307.
14. Petri M, Hochberg M, Hellmann D, et al. The Hopkins lupus cohort: a longitudinal study of predictors of thrombosis. Lupus. 1994;3:361 (Abstr.).
15. Ginsburg KS, Liang MH, Newcomer L, et al. Anticardiolipin antibodies and the risk for ischemic stroke and venous thrombosis. Ann Intern Med. 1992;117:997-1002.
16. Vianna JL, Khamashta MA, Ordi-Ros J, et al. Comparison of the primary and secondary antiphospholipid syndrome: a European multicenter study of 114 patients. Am J Med. 1994;96:3-9.
17. Levine SR, Brey RL, Joseph CLM, Havstad S. Risk of recurrent thrombotic events in patients with focal cerebral ischemia and antiphospholipid antibodies. Stroke. 1992;23 (Suppl 1):129-132.
18. Italian Registry of Antiphospholipid Antibodies. Thrombosis and thrombocytopenia in antiphospholipid syndrome (idiopathic and secondary to SLE). Haematologica. 1993;78:313-318.
19. Exner T, Rickard KA, Kronenberg H. A sensitive test demonstrating lupus anticoagulant and its behavioural patterns. Br J Haematol. 1978;40:143-151.
20. Thiagarajan P, Pengo V, Shapiro SS. The use of the dilute Russell viper venom time for the diagnosis of lupus anticoagulant. Blood. 1986;68:869-874.
21. Schleider MA, Nachman RL, Jaffe EA, Coleman M. A clinical study of the lupus anticoagulant. Blood. 1976;48:499-509.
22. Triplett DA, Brandt JT, Kaczor D, Schaeffer J. Laboratory diagnosis of lupus inhibition: a comparison of the tissue thromboplastin inhibition procedure with a new platelet neutralization procedure. Am J Clin Pathol. 1983;79:678-682.
23. Green D, Hougie C, Kazmier, et al. Report of the working party on acquired inhibitors of coagulation: studies of the "lupus" anticoagulant. Thromb Haemostas. 1983;49:144-146.
24. Exner T, Triplett DA, Taberner D, Machin SJ. Guidelines for testing and revised criteria for lupus anticoagulants. SSC Subcommittee for the standardization of lupus anticoagulants. Thromb Haemostas. 1991;65:320-322.
25. Harris EN, Gharavi AE, Patel SP, Hughes GRV. Evaluation of the anti-cardiolipin antibody test: report of an international workshop held 4 April 1986. Clin Exp Immunol. 1987;68:215-222.
26. Tan EN, Cohen AS, Fries JF, et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthrit Rheum. 1982;25:1271-1277.
27. Ramsey-Goldman R, Kulzer JE, Kuller LH, et al. Pregnancy outcome and anti-cardiolipin antibody in women with systemic lupus erythematosus. Am J Epidemiol. 1993;138:1057-1069.
28. Nencini P, Baruffi MC, Abbate R, et al. Lupus anticoagulant and anticardiolipin antibodies in young adults with cerebral ischemia. Stroke. 1992;23:189-193.
29. Sletnes KE, Smith P, Abelnoor M, et al. Antiphospholipid antibodies after myocardial infarction and their relation to mortality, reinfarction and non-haemorrhagic stroke. Lancet. 1992;339:451-453.
30. Muir KW, Squire IB, Alwan W, Lees KR. Anticardiolipin antibodies in an unselected stroke population. Lancet. 1994;344:452-456.
31. Khamashta MA, Cuadrado MJ, Mujic F, et al. The management of thrombosis in the antiphospholipid syndrome. NEJM. 1995;332:993-997.
32. Galli M, Finazzi G, Severs EM, Barbui T. Kaolin clotting time and dilute Russell's viper venom time distinguish between prothrombin-dependendent and b2-glycoprotein 1-dependent antiphospholipid antibodies. Blood. 1995;86:617-623.
33. Derksen RHWM, de Groot PG, Kater L, Nieuwenhuis HK. Patients with antiphospholipid antibodies and venous thrombosis should receive long term anticoagulant treatment. Ann Rheum Dis. 1993;52:689-692.
34. Rosove MH, Brewer PMC. Antiphospholipid thrombosis: clinical course after the first thrombotic event in 70 patients. Ann Intern Med. 1992;117:303-308.
35. Nasr S, Larson D, Parke A. Long term oral anticoagulants are not necessary to prevent recurrent thrombotic episodes in all patients with phospholipid antibodies. Lupus. 1994;3:361 (Abstr.).
36. Jude B, Goudemand J, Dolle I, et al. Lupus anticoagulant: a clinical study of 100 cases. Clin Lab Haematol. 1988;10:41-51.
37. Schved JF, Dupuy-Fons C, Biron C, et al. A prospective epidemiological study on the occurrence of antiphospholipid antibody; the Montpellier antiphospholipid (MAP) study. Haemostasis. 1994;24:175-182.
38. Stasi R, Stipa E, Masi M, et al. Antiphospnolipd antibodies: prevalence, clinical significance and correlation to cytokine levels in acute myeloid leukemia and non-Hodgkin's lymphoma. Thromb Haemostas. 1993;70:568-572.