GYP enzymes catalyze the formation of a terminal olefin from 2-ethylhexanoic acid in rat and human liver

Human and Experimental Toxicology

Volumn 15, Issue 5, 1996, Pages 435-442

  Pennanen, S ^a   Kojo, A ^b   Pasanen, M ^b   Liesivuori, J ^c   Juvonen, R O ^b   Komulainen, H ^a,b  

^a NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

^c FINNISH INSTITUTE OF OCCUPATIONAL HEALTH   (Finland)

Author keywords

2 ethylhexanoic acid; Cytochrome p450; Human liver; Man; Metabolism; Microsomes

Indexed keywords

2 ETHYLHEXANOL; ADIPIC ACID DERIVATIVE; ALKENE; ANTIBODY; CYTOCHROME P450; CYTOCHROME P450 REDUCTASE; METYRAPONE; PHENOBARBITAL; PROADIFEN; QUINIDINE; TROLEANDOMYCIN;

ANIMAL CELL; ARTICLE; CATALYSIS; GAS CHROMATOGRAPHY; LIVER MICROSOME; MALE; MASS SPECTROMETRY; METABOLISM; NONHUMAN; OCCUPATIONAL EXPOSURE; PRIORITY JOURNAL; RAT; URINE;

AGED; ANIMALS; ANTIBODIES, MONOCLONAL; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HEXANOIC ACIDS; HUMANS; ISOENZYMES; MALE; METHYLATION; METYRAPONE; MICE; MICROSOMES, LIVER; MIDDLE AGED; NADPH-FERRIHEMOPROTEIN REDUCTASE; OCCUPATIONAL EXPOSURE; PROADIFEN; QUINIDINE; RATS; RATS, WISTAR; TROLEANDOMYCIN;

ANIMALIA;

EID: 0029953241     PISSN: 09603271     EISSN: None     Source Type: Journal    
DOI: 10.1177/096032719601500512     Document Type: Article

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