Aberrant vascularity and von Willebrand factor distribution in inflamed synovial membrane

Journal of Rheumatology

Volumn 23, Issue 11, 1996, Pages 1880-1886

  Čeponis, Arnoldas ^a   Konttinen, Yrjö T ^a   MacKevičius, Zygmundas ^b   Solovieva, Svetlana A ^c   Hukkanen, Mika ^d   Tamulaitiene, Marija ^b   Matulis, Alfonsas ^b   Santavirta, Seppo ^e  

^a UNIVERSITY OF HELSINKI   (Finland)

^b Inst of Exp and Clinical Medicine

^c ORTON Research Institute   (Finland)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

^e HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

Arthritis; Endothelial cells; Immunohistochemistry; Synovial membrane vasuclature; von Willebrand factor; Weibel palade bodies

Indexed keywords

VON WILLEBRAND FACTOR;

ADOLESCENT; ADULT; ARTHRITIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; PRIORITY JOURNAL; SYNOVITIS; SYNOVIUM; VASCULARIZATION;

ADOLESCENT; ADULT; ARTHRITIS; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOHISTOCHEMISTRY; KNEE JOINT; MALE; MIDDLE AGED; NEOVASCULARIZATION, PATHOLOGIC; SYNOVIAL MEMBRANE; SYNOVITIS; VON WILLEBRAND FACTOR;

EID: 0029952937     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Wagner DD: Cell biology of von Willebrand factor. Annu Rev Celt Biol 1990;6:217-46.
2. Gordon JL, Pottinger BE, Woo P, Rosenbaum J, Black CM: Plasma von Willebrand factor in connective tissue disease. Ann Rheum Dis 1986;45-491-6.
3. Woolf AD, Wakerley G, Wallington TB, Scott DGI, Dieppe PA: Factor VIII related antigen in the assessment of vasculitis. Ann Rheum Dis 1987;46:441-7.
4. Blann AD, Hopkins J, Winkles J, Wainwright AC: Plasma and serum von Willebrand factor antigen concentrations in connective tissue disorders. Ann Clin Biochem 1992;29:67-71.
5. Levick JR: Hypoxia and acidosis in chronic inflammatory arthritis; relation to vascular supply and dynamic effusion pressure. J Rheumatol 1990;17:579-82.
6. Stevens CR, Blake DR, Merry P, Revell PA, Levick JR: A comparative study by morphometry of the microvasculature in normal and rheumatoid synovium. Arthritis Rheum 1991;34:1508-13.
7. Stevens CR, Williams RB, Farrell AJ, Blake DR: Hypoxia and inflammatory synovitis: Observations and speculation. Ann Rheum Dis 1991;50:124-32.
8. FitzGerald O, Soden M, Yanni G, Robinson R, Bresnihan B: Morphometric analysis of blood vessels in synovial membranes obtained from clinically affected and unaffected knee joints of patients with rheumatoid arthritis. Ann Rheum Dis 1991;50:792-6.
9. Yanni G, Whelan A, Feighery C, FitzGerald O, Bresnihan B: Morphometric analysis of synovial membrane blood vessels in rheumatoid arthritis: Associations with the immunohistologic features, synovial fluid cytokine levels and the clinical course. J Rheumatol 1993;20:634-8.
10. James MJ, Cleland LG, Rofe AM, Leslie A: Intraarticular pressure and the relationship between synovial perfusion and metabolic demand. J Rheumatol 1990;17:521-7.
11. Wilkinson LS, Edwards JCW: Microvascular distribution in normal human synovium. J Anat 1989;167:129-36.
12. Pearson JD: Markers of endothelial perturbation and damage. Br J Rheumatol 1993;32:651-2.
13. Bolosiu HD, Rus V, Parasca I, Dutu AI, Malide D: Von Willebrand factor in synovial fluid. Clin Exp Rheumatol 1991;9:395-8.
14. Blake DR, Merry P, Unsworth J, et al: Hypoxic-reperfusion injury in the inflamed human joint. Lancet 1989;1:289-93.
15. Farrell AJ, Williams RB, Stevens CR, Lawrie AS, Cox NL, Blake DR: Exercise induced release of von Willebrand factor: Evidence for hypoxic reperfusion microvascular injury in rheumatoid arthritis. Ann Rheum Dis 1992;51:1117-22.
16. Patel KD, Zimmerman GA, Prescott SM, McEver RP, McIntyre TM: Oxygen radicals induce human endothelial cells to express GMP-140 and bind neutrophils. J Cell Biol 1991;112:749-59.
17. Stevens CR, Allen RE, Sahinoglu T, Blake DR: Mechanisms of increased factor VIII related antigen release in ischaemia related to observations in rheumatoid arthritis (abstr). Br J Rheumatol 1990;(suppl 1)29:12.
18. Arnett FC, Edworthy SM, Bloch DA, et al: The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24.
19. Mayadas T, Wagner DD, Simpson PJ: von Willebrand factor biosynthesis and partitioning between constitutive and regulated pathways of secretion after thrombin stimulation. Blood 1989;73:706-11.
20. Rand JH, Patel ND, Schwartz E, Zhou S-L, Potter BJ: 150-kD von Willebrand factor binding protein extracted from human vascular subendothelium is type VI collagen. J Clin Invest 1991;88:253-9.
21. Sporn LA, Marder VJ, Wagner DD: von Willebrand factor released from Weibel-Palade bodies binds more avidly to extracellular matrix than that secreted constitutively. Blood 1957;69:1531-4.
22. Hattori R, Hamilton KK, McEver RP, Sims PJ: Complement proteins C5b-9 induce secretion of high molecular weight multimers of endothelial von Willebrand factor and translocation of granule membrane protein GMP-140 to the cell surface. J Biol Chem 1989;264:9053-60.
23. 2+ associated with von Willebrand factor release in human endothelial cells exposed to histamine. J Clin Invest 1987;79:600-8.
24. Konttinen YT, Reitamo S, Ranki A, Häyry P, Kankaanpää U, Wegelius O: Characterization of the immunocompetent cells of rheumatoid synovium from tissue sections and eluates. Arthritis Rheum 1981:24:71-9.
25. Konttinen YT, Bergroth V, Nordström D, et al: Cellular immunohistopathology of acute, subacute and chronic synovitis in rheumatoid arthritis. Ann Rheum Dis 1985;44:549-55.
26. Konttinen YT, Grönblad M, Bergroth V, Santavirta S, Antti-Poika I: Presence of platelet glycoproteins Ib and IIb-IIIa in inflammatory and noninflammatory synovium. J Rheumatol 1989;16:578-84.
27. Lorant DE, Patel KD, McIntyre TM, McEver RP, Prescott SM, Zimmerman GA: Coexpression of GMP-140 and PAF by endothelium stimulated by histamine or thrombin: A juxtacrine system for adhesion and activation of neutrophils. J Cell Biol 1991;115:223-34.
28. Winrow VR, Winyard PG, Morris CJ, Blake DR: Free radicals in inflammation: Second messengers and mediators of tissue destruction. Br Med Bull 1993;49:506-22.
29. Singh D, Nazhat NB, Fairburn K, Sahinoglu T, Blake DR, Jones P: Electron spin resonance spectroscopic demonstration of the generation of reactive oxygen species by diseased human synovial tissue following ex vivo hypoxia-reoxygenation. Ann Rheum Dis 1995;54:94-9.
30. Konttinen YT, Nordström D, Bergroth V, Leirisalo-Repo M, Skrifvars B: Cell-mediated immune response in the diseased joints in patients with reactive arthritis. Scand J Immunol 1986;23:685-91.
31. Saxne T, Glennås A, Kvien TK, Melby K, Heinegård D: Release of cartilage macromolecules into the synovial fluid in patients with acute and prolonged phase of reactive arthritis. Arthritis Rheum 1993;36:20-5.
32. Espinoza LR, Vasey FB, Espinoza CG, Bocanegra TS, Germain BF: Vascular changes in psoriatic synovium. A light and electron microscopic study. Arthritis Rheum 1982;25:677-84.
33. Veale D, Yanni G, Rogers S, Barnes L, Bresnihan B, FitzGerald O: Reduced synovial membrane macrophage numbers, ELAM-1 expression, and lining layer hyperplasia in psoriatic arthritis as compared with rheumatoid arthritis. Arthritis Rheum 1993;36:893-900.