메뉴 건너뛰기




Volumn 56, Issue 11, 1996, Pages 2626-2632

Resistance of a variant ras-transformed cell line to phenotypic reversion by farnesyl transferase inhibitors

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; LAMIN B; N [2 [2 (2 AMINO 3 MERCAPTOPROPYLAMINO) 3 METHYLPENTYLOXY] 3 PHENYLPROPIONYL]METHIONINE SULFONE METHYL ESTER; PROTEIN FARNESYLTRANSFERASE; RAS PROTEIN;

EID: 0029952467     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (44)

References (24)
  • 1
    • 0003132267 scopus 로고
    • ras gene mutations and human cancer
    • J. Cossman (ed.). Amsterdam: Elsevier Science Publishers, B.V.
    • Bos, J. L. ras gene mutations and human cancer. In: J. Cossman (ed.). Molecular Genetics in Cancer Diagnosis, pp. 273-287. Amsterdam: Elsevier Science Publishers, B.V. 1990.
    • (1990) Molecular Genetics in Cancer Diagnosis , pp. 273-287
    • Bos, J.L.1
  • 2
    • 0027239613 scopus 로고
    • Regulators and effectors of Ras
    • Lowy, D., and Willumsen, B. Regulators and effectors of Ras. Annu. Rev Biochem , 62: 851-891, 1993.
    • (1993) Annu. Rev Biochem , vol.62 , pp. 851-891
    • Lowy, D.1    Willumsen, B.2
  • 3
    • 0027521847 scopus 로고
    • Pathways of Ras function: Connections to the actin cytoskeleton
    • Prendergast, G. C., and Gibbs, J. B. Pathways of Ras function: connections to the actin cytoskeleton. Adv Cancer Res , 62: 19-63, 1993
    • (1993) Adv Cancer Res , vol.62 , pp. 19-63
    • Prendergast, G.C.1    Gibbs, J.B.2
  • 4
    • 0027175360 scopus 로고
    • Prevention of orthotopic human lung cancer growth by intratracheal instillation of a retroviral antisense K-ras construct
    • Georges, R N , Mukhopadhyay, T., Zhang, Y., Yen, N., and Roth, J. A. Prevention of orthotopic human lung cancer growth by intratracheal instillation of a retroviral antisense K-ras construct. Cancer Res. 53 1743-6, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 1743-1746
    • Georges, R.N.1    Mukhopadhyay, T.2    Zhang, Y.3    Yen, N.4    Roth, J.A.5
  • 5
    • 0027905014 scopus 로고
    • Altered growth of human colon cancer cell lines disrupted at activated Ki-Ras
    • Washington DC
    • Shirasawa, S , Furuse, M., Yokoyama, N., and Sasazuki, T. Altered growth of human colon cancer cell lines disrupted at activated Ki-Ras. Science (Washington DC), 260: 85-88, 1993.
    • (1993) Science , vol.260 , pp. 85-88
    • Shirasawa, S.1    Furuse, M.2    Yokoyama, N.3    Sasazuki, T.4
  • 6
    • 0012915993 scopus 로고
    • Lipid modifications of proteins in the Ras superfamily
    • L Birnbaumer and B. Dickey (eds.). New York: Springer-Verlag
    • Gibbs, J. B. Lipid modifications of proteins in the Ras superfamily. In: L Birnbaumer and B. Dickey (eds.). GTPases in Biology, pp. 335-344. New York: Springer-Verlag, 1993
    • (1993) GTPases in Biology , pp. 335-344
    • Gibbs, J.B.1
  • 7
    • 0026895892 scopus 로고
    • Protein prenylation: Key to Ras function and cancer intervention?
    • Khosravi-Far, R , Cox, A D., Kato, K , and Der, C. Protein prenylation: key to Ras function and cancer intervention? Cell Growth & Differ., 3: 461-469, 1992.
    • (1992) Cell Growth & Differ. , vol.3 , pp. 461-469
    • Khosravi-Far, R.1    Cox, A.D.2    Kato, K.3    Der, C.4
  • 8
    • 0026747866 scopus 로고
    • Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity
    • Kato, K., Cox, A D., Hisaka, M. M., Graham, S. M., Buss, J. E , and Der, C J. Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity Proc Natl. Acad. Sci. USA. 89: 6403-6407, 1992.
    • (1992) Proc Natl. Acad. Sci. USA , vol.89 , pp. 6403-6407
    • Kato, K.1    Cox, A.D.2    Hisaka, M.M.3    Graham, S.M.4    Buss, J.E.5    Der, C.J.6
  • 9
    • 0027320616 scopus 로고
    • Peptidomimetic inhibitors of Ras farnesylation and function in whole cells
    • Garcia, A. M , Rowell, C., Ackermann, K., Kowalczyk, J. J , and Lewis, M. D. Peptidomimetic inhibitors of Ras farnesylation and function in whole cells. J Biol. Chem., 268: 18415-18418, 1993.
    • (1993) J Biol. Chem. , vol.268 , pp. 18415-18418
    • Garcia, A.M.1    Rowell, C.2    Ackermann, K.3    Kowalczyk, J.J.4    Lewis, M.D.5
  • 15
    • 0028892646 scopus 로고
    • Evidence that farnesyl transferase inhibitors suppress Ras transformation by interfering with Rho activity
    • Lebowitz, P. F., Davide, J. P., and Prendergast, G. C Evidence that farnesyl transferase inhibitors suppress Ras transformation by interfering with Rho activity Mol. Cell. Biol., 15, 6613-6622, 1995.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6613-6622
    • Lebowitz, P.F.1    Davide, J.P.2    Prendergast, G.C.3
  • 16
    • 0028318136 scopus 로고
    • Farnesyltransferase inhibition causes morphological reversion of ras-transformed cells by a complex mechanism that involves regulation of the actin cytoskeleton
    • Prendergast, G. C., Davide, J. P., deSolms, S. J., Giuliani, E., Graham, S , Gibbs, J. B., Oliff, A., and Kohl, N. E. Farnesyltransferase inhibition causes morphological reversion of ras-transformed cells by a complex mechanism that involves regulation of the actin cytoskeleton. Mol. Cell. Biol., 14: 4193-4202, 1994.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 4193-4202
    • Prendergast, G.C.1    Davide, J.P.2    DeSolms, S.J.3    Giuliani, E.4    Graham, S.5    Gibbs, J.B.6    Oliff, A.7    Kohl, N.E.8
  • 18
    • 0028835253 scopus 로고
    • A peptidomimetic inhibitor of farnesyl.protein transferase blocks the anchorage- dependent and -independent growth of human lumor cell lines
    • Sepp-Lorenzino, L., Ma, Z., Rands, E., Kohl, N. E., Gibbs, J. B., Oliff, A., and Rosen, N A peptidomimetic inhibitor of farnesyl.protein transferase blocks the anchorage- dependent and -independent growth of human lumor cell lines Cancer Res., 55: 5302-5309, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 5302-5309
    • Sepp-Lorenzino, L.1    Ma, Z.2    Rands, E.3    Kohl, N.E.4    Gibbs, J.B.5    Oliff, A.6    Rosen, N.7
  • 19
    • 0024399048 scopus 로고
    • Human lamin B contains a farnesylated cysteine residue
    • Farnsworth, C. C , Wolda, S. L., Gelb, M. H., and Glomset, J. A. Human lamin B contains a farnesylated cysteine residue J. Biol. Chem., 264, 20422-20429, 1989.
    • (1989) J. Biol. Chem. , vol.264 , pp. 20422-20429
    • Farnsworth, C.C.1    Wolda, S.L.2    Gelb, M.H.3    Glomset, J.A.4
  • 20
    • 0027218689 scopus 로고
    • Biochemistry of multidrug-resistance mediated by the multidrug transporter
    • Gottesman, M. M., and Pastan, I. Biochemistry of multidrug-resistance mediated by the multidrug transporter Annu. Rev. Biochem , 62: 385-427, 1993.
    • (1993) Annu. Rev. Biochem , vol.62 , pp. 385-427
    • Gottesman, M.M.1    Pastan, I.2
  • 21
    • 0026659959 scopus 로고
    • Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras function
    • Cox, A. D.. Hisaka, M. M., Buss, J E., and Der, C. J Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras function. Mol. Cell Biol., 12: 2606-2615, 1992
    • (1992) Mol. Cell Biol. , vol.12 , pp. 2606-2615
    • Cox, A.D.1    Hisaka, M.M.2    Buss, J.E.3    Der, C.J.4
  • 23
    • 0022472990 scopus 로고
    • Requirement for c-ras proteins during viral oncogene transformation
    • Smith, M. R., DeGudicibus, S. J., and Stacey, D. W. Requirement for c-ras proteins during viral oncogene transformation. Nature (Lond.), 320: 540-543, 1986.
    • (1986) Nature (Lond.) , vol.320 , pp. 540-543
    • Smith, M.R.1    DeGudicibus, S.J.2    Stacey, D.W.3
  • 24
    • 0020408261 scopus 로고
    • Characterization of the phosphorylation sites and the surrounding amino acid sequences of the p21 transforming proteins coded for by the Harvey and Kirsten strains of murine sarcoma viruses
    • Shih, T. Y., Stokes, P. E., Smythers, G. W., Dhar, R., and Oroszlan, S. Characterization of the phosphorylation sites and the surrounding amino acid sequences of the p21 transforming proteins coded for by the Harvey and Kirsten strains of murine sarcoma viruses. J. Biol. Chem., 257 11767-11773, 1982.
    • (1982) J. Biol. Chem. , vol.257 , pp. 11767-11773
    • Shih, T.Y.1    Stokes, P.E.2    Smythers, G.W.3    Dhar, R.4    Oroszlan, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.