Synthesis of aryl 2-benzofuranyl and aryl 2-indolyl carbinols of high enantiomeric purity via palladium-catalyzed heteroannulation of chiral arylpropargylic alcohols

Tetrahedron Asymmetry

Volumn 7, Issue 5, 1996, Pages 1263-1266

  Botta, Maurizio ^a   Summa, Vincenzo ^a   Corelli, Federico ^a   Di Pietro, Giovanna ^b   Lombardi, Paolo ^b  

^a UNIVERSITY OF SIENA   (Italy)

^b Menarini Ricerche SpA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BENZOFURAN DERIVATIVE; INDOLE DERIVATIVE;

ARTICLE; DRUG PURITY; DRUG SYNTHESIS; ENANTIOMER; PRIORITY JOURNAL; REACTION ANALYSIS;

EID: 0029952317     PISSN: 09574166     EISSN: None     Source Type: Journal    
DOI: 10.1016/0957-4166(96)00138-3     Document Type: Article

References (18)

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16. Not optimized yields refer to isolated and purified materials. All the new compounds gave satisfactory microanalyses and showed spectroscopic data in accordance with the assigned structures.
17. For the preparation of these enantiomerically pure propargylic alcohols, see the preceding paper in this issue.
18. Attempts to prepare compounds 1 by enantiospecific reduction of the corresponding ketones were unsuccessful.