Theoretical relationship between the post-administration time and plasma or urinary concentration of a metabolite and the unchanged drug. Administration of caffeine to horses

Biological and Pharmaceutical Bulletin

Volumn 19, Issue 10, 1996, Pages 1341-1346

  Aramaki, Sugako ^a   Ishidaka, Osamu ^a   Suzuki, Etsuko ^a   Momose, Atsushi ^a   Umemura, Koshiro ^b  

^a LABORATORY OF RACING CHEMISTRY   (Japan)

^b TOHO UNIVERSITY   (Japan)

Author keywords

administration time; caffeine; doping; horse; metabolite ratio; pharmacokinetics

Indexed keywords

CAFFEINE; DRUG METABOLITE; ILLICIT DRUG; THEOBROMINE; THEOPHYLLINE; XANTHINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOAVAILABILITY; CONTROLLED STUDY; DOPING; DOSE TIME EFFECT RELATION; DRUG BLOOD LEVEL; DRUG HALF LIFE; HORSE; INTRAMUSCULAR DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; METABOLIC REGULATION; NONHUMAN; ORAL DRUG ADMINISTRATION; URINARY EXCRETION;

EID: 0029951671     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.19.1341     Document Type: Article

References (4)

1. Aramaki S., Suzuki E., Ishidaka O., Momose A., Umemura K., Chem. Pharm. Bull., 39, 2999-3002 (1991).
2. Kamei K., Matsuda M., Momose A., Chem. Pharm. Bull., 23, 683-685 (1975).
3. Nishigaki R., Umemura K., Okui K., Hayashi T., Yamamoto T., Sakurai Y., Yakugaku Zasshi, 106, 906-915 (1986).
4. Nishigaki R., Umemura K., Okui K., Hayashi T., Yamamoto T., Sakurai Y., Yakugaku Zasshi. 106, 916-923 (1986).