Intestinal permeability in exocrine pancreatic insufficiency due to cystic fibrosis or chronic pancreatitis

Pediatric Research

Volumn 39, Issue 6, 1996, Pages 985-991

  Van Elburg, Ruurd M ^a,c   Uil, Jan J ^b   Van Aalderen, Wim M C ^a   Mulder, Chris J J ^b   Heymans, Hugo S A ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b RIJNSTATE HOSPITAL   (Netherlands)

^c Sophia Hospital   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

KREON; LACTULOSE; MANNITOL; PANCREAS ENZYME; PANCRELIPASE; PANZYTRAT; SUCROSE; SUGAR; TRIACYLGLYCEROL LIPASE;

ADOLESCENT; ADULT; ARTICLE; CARBOHYDRATE ABSORPTION; CHILD; CHRONIC PANCREATITIS; CONTROLLED STUDY; CYSTIC FIBROSIS; DIGESTIVE SYSTEM FUNCTION DISORDER; DRUG CAPSULE; HUMAN; INFANT; INTESTINE CRYPT; INTESTINE MUCOSA PERMEABILITY; INTESTINE VILLUS; MAJOR CLINICAL STUDY; NUTRITIONAL STATUS; ORAL DRUG ADMINISTRATION; OSMOLARITY; PANCREAS EXOCRINE INSUFFICIENCY; PRIORITY JOURNAL; SUPPLEMENTATION; TIGHT JUNCTION;

EID: 0029951660     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/00006450-199606000-00010     Document Type: Article

References (36)

1. Travis S, Menzies IS 1992 Intestinal permeability: functional assessment and signficance. Clin Sci 82:471-488
2. Van Elburg RM, Uil JJ, Mulder CJJ, Heymans HSA 1993 Intestinal permeability in patients with coeliac disease and relatives of patients with coeliac disease. Gut 34:354-357
3. Van Elburg RM, Uil JJ, De Monchy JGR, Heymans HSA 1992 Intestinal permeability in pediatric gastroenterology. Scand J Gastroenterol 27(suppl 194):19-24
4. Menzies IS 1974 Absorption of intact oligosaccharides in health and disease. Biochem Soc Trans 2:1042-1047
5. Menzies IS 1983 Transmucosal passage of inert molecules in health and disease. In: Skadhauge E, Heintze K (eds) Intestinal Absorption and Secretion. Falk Symposium 36. MTP Press, Lancaster, pp 527-543
6. Wheeler PG, Menzies IS, Creamer B 1978 Effect of hyperosmolar stimuli and coeliac disease on the permeability of the human gastrointestinal tract. Clin Sci Mol Med 54:495-501
7. Heymans HSA 1989 Gastrointestinal dysfunction and its effect on nutrition in CF. Acta Paediatr Scand Suppl 363:74-79
8. 51Cr]EDTA in children with cystic fibrosis. J Pediatr Gastroenterol Nutr 5:384-387
9. Leclercq-Foucart J, Forget PP, Van Cutsem JL 1987 Lactulose-rhamnose intestinal permeability in children with cystic fibrosis. J Pediatr Gastroenterol Nutr 6:66-70
10. Dalzell AM, Freestone NS, Billington D, Heaf DP 1990 Small intestinal permeability and orocaecal transit time in cystic fibrosis. Arch Dis Child 65:585-588
11. Murphy MS, Sheldon W, Brunetto A, Pearson ADJ, Laker MF, Eastham EJ, Nelson R 1989 Active and passive sugar absorption in pancreatic insufficiency. J Pediatr Gastroenterol Nutr 8:189-194
12. Mack DR, Flick JA, Durie PR, Rosenstein BJ, Ellis LE, Perman JA 1992 Correlation of intestinal lactulose permeability with exocrine pancreatic dysfunction. J Pediatr 120:696-701
13. Schaad U, Kraemer R, Gaze G, Hadorn B 1978 One-hour blood xylose in cystic fibrosis. Arch Dis Child 53:756-757
14. di Sant'Agnese PA, Darling RC, Perera GA 1953 Sweat electrolyte disturbances associated with childhood pancreatic disease. Am J Med 15:777-784
15. Schmerling DH, Forrer JCW, Prader A 1970 Fecal fat and nitrogen in healthy children and in children with malabsorption or maldigestion. Pediatrics 46:690-695
16. Van Elburg RM, Uil JJ, Kokke FTM, Mulder AM, van de Broek WGM, Mulder CJJ, Heymans HSA 1995 Repeatability of the sugar absorption test, using lactulose and mannitol, for measuring intestinal permeability for sugars. J Pediatr Gastroenterol Nutr 20:184-188
17. Jansen G, Muskiet FAJ, Schierbeek H, Berger R, Van der Slik W 1986 Capilary gas chromatographic profiling of urinary, plasma derivates, preceded by a simple and rapid prepurification method. Clin Chim Acta 157:277-294
18. Cox KL, Isenberg JN, Ament ME 1982 Gastric acid hypersecretion in cystic fibrosis. J Pediatr Gastroenterol Nutr 1:559-565
19. Senelas-Balas F, Bastie MJ, Balas D, Escourrou J, Bommelaer G, Bertrand C, Arany Y, Ribet A 1982 Histological variations of the duodenal mucosa in chronic human pancreatitis. Dig Dis Sci 27:917-922
20. Eggermont E, De Boeck K 1991 Small intestinal abnormalities in cystic fibrosis patients. Eur J Pediatr 150:824-828
21. Oppenheimer EH, Esterly JR 1975 Pathology of cystic fibrosis. Review of the literature and comparison with 146 autopsies cases. Perspect Pediatr Pathol 2:241-278
22. Gosden CM, Gosden JR 1984 Fetal abnormalities in cystic fibrosis suggest a deficiency in proteolysis of cholecystokinin. Lancet 2:541-546
23. Lunn PG, Northrop-Clewes CA, Downes RM 1991 Intestinal permeability, mucosal injury, and growth faltering in Gambian infants. Lancet 338:907-910
24. Heyman M, Boudraa G, Sarrut S, Giraud M, Evans L, Touhami M, Desjeux JF 1984 Macromolecular transport in jejunal mucosa of children with severe malnutrition: a quantitative study. J Pediatr Gastroenterol Nutr 3:357-363
25. Sinaasappel M 1992 Relationship between intestinal function and chloride secretion in patients with cystic fibrosis. Neth J Med 41:110-4
26. Layer P, Rippel K, von der Ohe M, Groger G, Holtmann G, Goebell H 1993 Altered fed and interdigestive intestinal motility in severe pancreatic insufficiency. Gastroenterology 104:A539
27. Bali A, Stableforth DE, Asquith P 1983 Prolonged small-intestinal transit time in cystic fibrosis. BMJ 287:1011-1012
28. 51Cr-EDTA and orocaecal transit time in cystic fibrosis. J Pediatr Gastroenterol Nutr 14:204-207
29. Brunetto AL, Pearson ADJ, Gibson R, Bateman DN, Rashid MU, Laker MF 1990 The effect of pharmacological modification of gastric emptying and mouth-to-caecum transit time on the absorption of sugar probe marker molecules of intestinal permeability in normal man. Eur J Clin Invest 20:279-284
30. Baxter P, Goldhill J, Hardcastle J, Hardcastle PT, Taylor CJ 1990 Enhanced intestinal glucose and alanine transport in cystic fibrosis. Gut 31:817-820
31. Pappenheimer JR, Volpp K 1992 Transmucosal impedance of small intestine: correlation with transport of sugars and amino acids. Am J Physiol 263:C480-C493
32. Bijlsma PB, Peeters RA, Groot JA, Dekker PR, Taminiau JAJM, Meer R van der 1995 Differential in vivo and in vitro intestinal permeability to lactulose and mannitol in animals and man: a hypothesis. Gastroenterology 108:687-696
33. Gryboski JD, Thayer WR, Gabrielson IW, Spiro HM 1963 Disacchariduria in gastrointestinal disease. Gastroenterology 45:633-637
34. Hollander D 1992 The intestinal permeability barrier. A hypothesis as to its regulation and involvement in Crohn's disease. Scand J Gastroenterol 27:721-726
35. Fasano A, Budillon G, Guandalini S, Cuomo R, Parrilli G, Cangiotti AM, Morroni M, Rubino A 1990 Bile acids reversible effects on small intestinal permeability. An in vitro study in the rabbit. Dig Dis Sci 35:801-8
36. Roy CC, Weber AM, Lepage G, Smith L, Levy E 1988 Digestive and absorptive phase anomalies associated with exocrine pancreatic insufficiency of cystic fibrosis. J Pediatr Gastroenterol Nutr 7(suppl):S1-S7