Application of immunocytochemistry for detection of proliferating cell populations during tooth development

Anatomical Record

Volumn 245, Issue 2, 1996, Pages 162-173

  Casasco, Andrea ^a  

^a UNIVERSITY OF PAVIA   (Italy)

Author keywords

Cell cycle; Cell differentiation; Cell proliferation; Flow cytometry; Immunocytochemistry; Odontogenesis; Tooth germ

Indexed keywords

BROXURIDINE; CYCLINE; GROWTH FACTOR; MONOCLONAL ANTIBODY;

CELL CYCLE PHASE; CELL DIFFERENTIATION; CELL GROWTH; CELL KINETICS; CELL POPULATION; CELL PROLIFERATION; DENTIN; ENAMEL; GENE EXPRESSION; HUMAN; IMMUNOCYTOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; REVIEW; TOOTH DEVELOPMENT;

ANIMALS; ANIMALS, NEWBORN; BIOLOGICAL MARKERS; CELL CYCLE; CELL DIFFERENTIATION; CELL DIVISION; IMMUNOHISTOCHEMISTRY; MATURATION-PROMOTING FACTOR; ODONTOGENESIS; PROLIFERATING CELL NUCLEAR ANTIGEN; RATS; TOOTH;

EID: 0029951596     PISSN: 0003276X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0185(199606)245:2<162::AID-AR5>3.0.CO;2-Z     Document Type: Review

References (139)

1. Ansari, B., R. Dover, C.P. Gillmore, and P.A. Hall 1993 Expression of the nuclear membrane protein statin in cycling cell. J. Pathol., 169:391-396.
2. Black, A., J.W. Freeman, G. Zhou, and H. Busch 1987 Novel cell cycle-related nuclear proteins found in rat and human cells with monoclonal antibodies. Cancer Res., 47:3266-3272.
3. Bravo, R., and H. Macdonald-Bravo 1985 Changes in the nuclear distribution of cyclin (PCNA) but not its synthesis depend on DNA replication. EMBO J., 4:655-661.
4. Bravo, R., and H. Macdonald-Bravo 1987 Existence of two populations of cyclin-proliferating cell nuclear antigen during the cell cycle: association with DNA replication sites. J. Cell Biol., 1051549-1554.
5. Bronckers, A.L.J.J., S. Gay, R.D. Finkelman, and W.T. Butler 1987 Immunolocalization of Gla proteins (osteocalcin) in rat tooth germs: comparison between indirect immunofluorescence, peroxidase-antiperoxidase, avidin-biotin-peroxidase complex, and avidin-biotin-gold complex with silver enhancement. J. Histochem. Cytochem., 35:825-830.
6. Cardoso, M.C., H. Leonhardt, and B. Nadal-Ginard 1993 Reversal of terminal differentiation and control of DNA replication: Cyclin A and Cdk2 specifically localize at subnuclear sites of DNA replication. Cell, 74:979-992.
7. Casasco, A., A. Calligaro, E. Casasco, C. Marchetti, P. Poggi, and M. Casasco 1988 An immunocytochemical method for studying embryo cytokinetics. Bas. Appl. Histochem., 32:293-296.
8. Casasco, A., A. Calligaro, C. Marchetti, P. Poggi, S. Brugnatelli, M. Danova, and R. Fiocca 1989a Immunocytochemical detection of proliferating cells in the rat tooth germ by monoclonal antibodies against 5-bromo-2′-deoxyuridine. Archs. Oral Biol., 34:65-69.
9. Casasco, A., A. Calligaro, C. Marchetti, P. Poggi, M. Casasco, and P. Menghini 1989b Etude immunocytochimique du développement de la cavité buccale du rat. Bull. Group. Int. Rech. Sc. Stomat. Odont., 32:13-17.
10. Casasco, A., A. Calligaro, and M. Casasco 1992 Proliferative and functional stages of rat ameloblast differentiation as revealed by combined immunocytochemistry against enamel matrix proteins and bromodeoxyuridine. Cell Tissue Res., 270:415-423.
11. Casasco, A., M. Giordano, M. Danova, M. Casasco, A. Icaro Cornaglia, and A. Calligaro (1993) PC10 monoclonal antibody to proliferating cell nuclear antigen as probe for cycling cell detection in developing tissues. Histochemistry, 99:191-199.
12. Casasco, A., M. Casasco, A. Icaro Cornaglia, M. Danova, M. Giordano, and A. Calligaro (1994a) Tissue fixation for immunohistochemical detection of proliferating cell nuclear antigen with PC10 monoclonal antibody. Biotech. Histochem., 69:112-117.
13. Casasco, A., E. Maserati, M. Giordano, M. Casasco, M. Ciuffreda, S. Sander, M. Danova, S. Scappaticci, A. Calligaro, D.R. Springall, and J.M. Polak 1994b Stimulation of DNA synthesis by endothelin-1 in primary cultures of human dental pulp. Archs. Oral Biol., 39:245-249.
14. Casasco, A., M. Casasco, A. Icaro Cornaglia, G. Mazzini, R. De Renzis, and S. Tateo 1995 Detection of bromo-deoxyuridine- and proliferating cell nuclear antigen-immunoreactivities in tooth germ. Connect. Tissue Res. 32:63-70.
15. Celis, J.E., R. Bravo, P.M. Larsen, and S.J. Fey 1984 Cyclin: A nuclear protein whose level correlates directly with the proliferative state of normal as well as transformed cells. Leukemia Res., 8:143-157.
16. Celis, J.E., and A. Celis 1985 Cell cycle-dependent variations in the distribution of the nuclear protein cyclin proliferating cell nuclear antigen in cultured cells: Subdivision of S phase. Proc. Natl. Acad. Sci. USA, 82:3262-3266.
17. Chiba, M., K. Nakagawa, and T. Mimura 1967 DNA synthesis and cell division cycle at the base of the maxillary incisor tooth of the young rat. Archs. Oral Biol., 12:865-876.
18. Cho, M.I., and R.R. Garant 1988 Ultrastructural evidence of direct cell migration during initial cementoblast differentiation in root formation. J. Periodont. Res., 12:268-276.
19. Christensen, L.R., K. Mollgard, I. Kjaer, M. Stagaard Janas, 1993 Immunocytochemical demonstration of nerve growth factor receptor (NGF-R) in developing human fetal teeth. Anat. Embryol., 188:247-255.
20. Clevenger, C.V., and A.L. Epstein 1984 Identification of a nuclear protein component of interchromatin granules using a monoclonal antibody and immunogold electron microscopy. Exp. Cell Res., 151:194-207.
21. Clevenger, C.V., A.L. Epstein, and K.D. Bauer 1987a Quantitative analysis of a nuclear antigen in interphase and mitotic cells. Cytometry, 8:280-286.
22. Clevenger, C.V., A.L. Epstein, and K.D. Bauer 1987b Modulation of the nuclear antigen p105 as a function of cell-cycle progression. J. Cell. Physiol., 130:336-343.
23. Coltrera, M.D., and A.M. Gown 1991 PCNA/cyclin expression and BrdU uptake define different subpopulations in different cell lines. J. Histochem, Cytochem., 39:23-30.
24. Cotton, W.R. 1964 Demonstration of odontoblast precursor cell by tritiated thymidine. J. Dent. Res., 43:810.
25. 3-thymidine. Ann. N.Y. Acad. Sci., 77:803-820.
26. Danova, M., G. Wilson, G. Ucci, G. Mazzini, P. Giordano, M. Giordano, and A. Riccardi 1986 Comparison between bromodeoxyuridine and iododeoxyuridine for cytokinetic studies: a flow cytofluorimetric analysis. Bas. Appl. Histochem., 30:63.
27. Danova, M., A. Riccardi, S. Brugnatelli, R. Fiocca, M. Girino, L. Villani, P. Giordano, P. Dionigi, M. Giordano, M. Buttini, G. Ucci, and G. Mazzini 1988a In vivo bromodeoxyuridine incorporation in human gastric cancer: A study on formalin-fixed and paraffin-embedded sections. Histochem. J., 20:125-130.
28. Danova, M., A. Riccardi, P. Gaetani, G.D. Wilson, G. Mazzini, S. Brugnatelli, R. Buttini, Butti, G. Ucci P. Paoletti, and E. Ascari 1988b Cell kinetics of human brain tumors: In vivo study with bromodeoxyuridine and flow cytometry. Eur. J. Cancer Clin. Oncol., 24: 873-880.
29. Dean, P.N., F. Dolbeare, H. Gratzner, G.C. Rice, and J.W. Gray 1984 Cell-cycle analysis using a monoclonal antibody to BrdUrd. Cell Tissue Kinet, 17:427-436.
30. Decker, J.D. 1963 A light and electron microscope study of the rat molar enamel organ. Archs. Oral Biol., 8:301-310.
31. deFazio, A., J.A. Leary, D.W. Hedley, and M.H.N. Tattersall 1987 Immunohistochemical detection of proliferating cells in vivo. J. Histochem. Cytochem., 35:571-577.
32. Dolbeare, F., H. Gratzner, M.G. Pallavicini, and J. Gray (1983) Flow cytometric measurement of total DNA content and incorporated bromodeoxyuridine. Proc. Natl. Acad. Sci. USA, 80:5573-5577.
33. D'Souza, R.N., A.L.J.J. Bronckers R.-P. Happonen, D.W. Doga, M.C. Farach-Carson, and W.T. Butler 1992 Developmental expression of a 53 kd dentin sialoprotein in rat tooth organs. J. Histochem. Cytochem., 40:359-366.
34. 3H thymidine into damaged pulp of rat incisor. J. Dent. Res., 49:783-786.
35. Fitzgerald, M., D.J. Chiego Jr., and D.R. Heys 1990 Autoradiographic analysis of odontoblast replacement following pulp exposure in primate teeth. Archs. Oral Biol., 35:707-715.
36. Gallant, P., and E.A. Nigg 1992 Cyclin B2 undergoes cell cycle-dependent nuclear translocation and, when expressed as a non-destructible mutant, causes mitotic arrest in HeLa cells. J. Cell Biol., 117:213-224.
37. Gerdes, J., U. Schwab, H. Lemke, and H. Stein 1983 Production of a monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation. Int. J. Cancer, 31:13-20.
38. Gerdes, J., H. Lemke, H. Baisch, H.H. Wacker, U. Schwab, and H. Stein 1984 Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. J. Immunol., 133:1710-1715.
39. Gerdes, J. 1985 An immunohistological method for estimating cell growth fractions in rapid histopathological diagnosis during surgery. Am. J. Cancer, 35:169-171.
40. Gonchoroff, N.J., J.A. Katzmann, R.M. Currie, E.L. Evans, D.W. Houck, B.C. Kline, P.R. Greipp, and M.R. Loken 1986 S-phase detection with an antibody to bromodeoxyuridine. Role of DNase pretreatment. J. Immunol. Methods, 93:97-101.
41. Gorter de Vries, I., E. Quartier, A. Van Steirteghem, P. Boute, D. Coomans, and E. Wisse 1986 Characterization and immunocytochemical localization of dentine phosphoprotein in rat and bovine teeth. Archs. Oral Biol., 31:57-66.
42. Gorter de Vries, I., and E. Wisse 1989 Ultrastructural localization of dentine phosphoprotein in rat tooth germs by immunogold staining. Histochemistry, 91:69-75.
43. Gratzner, H. 1982 Monoclonal antibody to 5-bromo- and 5-iododeoxyuridine: A new reagent for detection of DNA replication. Science, 218:474-475.
44. Hoshino, T., T. Nagashima, J. Murovic, E.M. Levin, V.A. Levin, and S.M. Rupp 1985 Cell kinetic studies of in situ human brain tumors with bromodeoxyuridine. Cytometry, 6:627-632.
45. 32 as demonstrated by autoradiographs. Exp. Cell Res., 2:178-187.
46. Howard, A., and S.R. Pelc 1953 Synthesis of deoxyribonucleic acid in normal and irradiated cells and its relation to chromosome breakage. Heredity, 6(suppl):261-273.
47. Hughes, W.L., V.P. Bond, G. Brecher, E.P. Cronkite, R.B. Painter, H. Quastler, and F.G. Sherman 1958 Cellular proliferation in the mouse as revealed by autoradiography with tritiated thymidine. Proc. Natl. Acad. Sci. USA, 44:476-483.
48. Hunt, A.M., and K.J. Paynter 1963 The role of cells of the stratum intermedium in the development of the guinea pig molar: A study of cell differentiation and migration using tritiated thymidine. Archs. Oral Biol., 8:65-78.
49. 3TDR). J. Dent. Res., 44:42-53.
50. Hwang, W.S.S., E.P. Cronkite, and E.A. Tonna 1966 Cell proliferation kinetics of the internal enamel epithelium of mouse incisors. J. Dent. Res., 45:350-358.
51. Kallenbach, E. 1971 Electron microscopy of the differentiating rat incisor ameloblast. J. Ultrastruct. Res., 35:508-531.
52. Kollar, E. 1983 Epithelial-mesenchymal interaction in the mammalian integument: tooth germ as a model for instructive induction. In: Epithelial-Meaenchymal Intercations in Development. R.G Sawer, J.F. Fallon, eds. Praeger, New York, pp. 27-50.
53. Kurki, P., M. Vanderlaan, F. Dolbeare, J. Gray, and E.M. Tan 1986 Expression of proliferating cell nuclear antigen (PCNA)/cyclin during the cell cycle. Exp. Cell Res., 166:209-219.
54. Kurki, P., K. Ogata, and E.M. Tan 1988 Monoclonal antibodies to proliferating cell nuclear antigen (PCNA)/cyclin as probes for proliferating cells by immunofluorescence microscopy and flow cytometry. J. Immunol. Methods, 109:49-59.
55. Landberg, G., and G. Roos 1991 Antibodies to proliferating cell nuclear antigen as S-phase probes in flow cytometric cell cycle analysis. Cancer Res., 51:4570-4574.
56. 3 as a tool for the investigation of the renewal of cell populations. Lab. Invest., 8:296-308.
57. Leblond, C.P., and H. Cheng 1976 Identification of stem cells in the small intestine of the mouse. In: Stem Cells of Renewing Cell Populations. A.B. Cairne, P.K. Lala, D.G. Osmond, eds. Academic Press, New York, pp. 7-31.
58. Leblond, C.P. 1981 The life history of cells in renewing systems. Am. J. Anat., 712:187-204.
59. Lipkin, M. 1971 The proliferative cycle of mammalian cells. In: The Cell Cycle and Cancer. R. Baserga, ed. Marcel Dekker, New York, pp. 6-26.
60. Lumsden, A.G.S. 1979 Pattern formation in the molar dentition of the mouse. J. Biol. Buccale, 7:77-103.
61. Lumsden, A.G.S. 1988 Spatial organization of the epithelium and the role of neural crest cells in the initiation of the mammalian tooth germ. Development, 103(suppl), 155-169.
62. McCormick, D., and P.A. Hall 1992 The complexities of proliferating cell nuclear antigen. Histopathology, 21:591-594.
63. McCormick, D., H. Chong, C. Datta, and P.A. Hall 1993 Detection of the Ki-67 antigen in fixed and wax-embedded sections with the monoclonal antibody MIB1. Histopathology, 22:355-360.
64. Malamud, D. 1971 Differentiation and the cell cycle. In: The Cell Cycle and Cancer. R. Baserga, ed. Marcel Dekker, New York, pp. 132-141.
65. Marcote, M.J., M. Pagano, and G. Draetta 1992 cdc2 protein kinase: structure-function relationships. In: Regulation of the Eukaryotic Cell Cycle. J. Marsch, ed. John Wiley & Sons, Chichester, pp. 30-41.
66. Mazzotti, G., R. Rizzoli, A. Galanzi, S. Papa, M. Vitale, M. Falconi, L.M. Neri, N. Zini, and N.M. Maraldi 1990 High-resolution detection of newly synthesized DNA by anti-bromodeoxyuridine antibodies identified specific chromatin domains. J. Histochem. Cytochem., 38:13-22.
67. 3 into male rats and mice. Am. J. Anat., 106:247-285.
68. Morris, S.M. 1991 The genetic toxicology of 5-bromodeoxyuridine in mammalian cells. Mutat. Res., 258:161-188.
69. Morstyn, G., S.M. Hsu, T. Kinsella, H. Gratzner, A. Russo, and J.B. Mitchell 1983 Bromodeoxyuridine in tumors and chromosomes detected with a monoclonal antibody. J. Clin. Invest., 72:1844-1850.
70. Morstyn, G., K. Pyke, J. Gardner, R. Ashcroft, A. deFazio, and P. Bhathal, 1986 Immunoshistochemical identification of proliferating cells in organ culture using bromodeoxyuridine and a monoclonal antibody. J. Histochem. Cytochem., 34:697-701.
71. Murray, A.W. 1987 Cyclins in meiosis and mitosis. Nature, 326:542-543.
72. Nanci, A., M. Bendayan, and H.C. Slavkin 1985 Enamel protein biosynthesis and secretion in mouse incisor secretory ameloblasts as revealed by high-resolution immunocytochemistry. J. Histochem. Cytochem., 33:1153-1160.
73. Nanci, A., H.C. Slavkin, and C.E. Smith 1987 Application of high-resolution immunocytochemistry to the study of the secretory, resorptive, and degradative functions of ameloblasts. Adv. Dent. Res., 1:148-161.
74. cdc2 protein kinase activity by phosphorylation and cyclin binding. In: Regulation of the Eukaryotic Cell Cycle. J. Marsch, ed. John Wiley & Sons, Chichester, pp. 72-84.
75. Norel, R., and Z. Agur 1991 A model for the adjustment of the mitotic clock by cyclin and MPF levels. Science, 251:1076-1078.
76. Nso, M., B. Senger, and J.V. Ruch 1975 Scoring mitotic activity in longitudinal sections of mouse embryonic incisors: significant differences exist for labial and lingual inner dental epithelia. J. Craniofac. Genet. Dev. Biol., 12:159-166.
77. Ogata, K., P, Kurki, J.E. Celis, R.M. Nakamura, and E.M. Tan 1987 Monoclonal antibodies to a nuclear protein (PCNA/cyclin) associated with DNA replication. Exp. Cell Res., 168:475-486.
78. Olson, E.N. 1992 Interplay between proliferation and differentiation within the myogenic lineage. Dev. Biol., 154:261-272.
79. Osman, A., and J.V. Ruch 1975 Répartition topographique des mitoses dans les territoires odontogenèses de la machoire inférieure de l'embryon de souris. J. Biol. Buccale, 3:117-132.
80. ère molaire inférieures de l'embryon de souris. J. Biol. Buccale, 4:331-348.
81. Osman, A., and J.V. Ruch 1978 Contribution à l'étude des paramètres du cycle cellulaire au cours de l'odontogenèse chez la souris. J. Biol. Buccale, 6:43-54.
82. Patt, H., and H. Quastler 1963 Radiation effects on cell renewal and related systems. Physiol. Rev., 43:357-396.
83. Pellicciari, C., M. Danova, M. Giordano, A.M. Fuhrman-Conti, G. Mazzini, E. Wang, E. Ronchetti, A. Riccardi, and M.G. Manfredi-Romanini 1991 Expression of cell cycle related proteins-proliferating cell nuclear antigen (PCNA) and statin-during adaptation and de-adaptation of EUE cells to a hypertonic medium. Cell Prolif., 24:469-479.
84. Pfeffer, U., and G. Vidali 1991 A novel protein related to cell cycle-dependent alterations of chromatin structures. Exp. Cell Res., 193:411-419.
85. Pfeffer, U., A. Di Vinci, G. Vidali, and W. Giaretti 1991 Cell cycle dependent alterations of chromatin structure in situ as revealed by the accessibility of the nuclear protein AF-2 to monoclonal antibodies. J. Cell. Physiol., 149:567-574.
86. Philipova, R., N. Zhelev, I. Todorov, and A. Hadjiolov 1987 Monoclonal antibody against a nuclear matrix antigen in proliferating human cells. Biol. Cell, 60:1-8.
87. Pines, J., and T. Hunter 1992 Cycling A and Bl in the human cell cycle. In: Regulation of the Eukaryotic Cell Cycle. J. Marsch, ed. John Wiley & Sons, Chichester, pp. 187-196.
88. Pinzon, R.D., P.D. Toto, and J. O'Malley 1966 Kinetics of rat molar pulp cells at various ages. J. Dent. Res., 45:934-939.
89. Potten, C.S. 1974 The epidermal proliferative unit: the possible role of the central basal cell. Cell Tissue Kinet., 1:77-88.
90. Potten, C.S., and M. Loeffler 1990 Stem cells: Attributes, cycles, spirals, pitfalls and uncertainties lessons for and from the crypt. Development, 110:1001-1020.
91. Prelich, G., C.K. Tan, M. Kostura, M.B. Mathews, and A.G. So (1987) Functional identity of proliferating cell nuclear antigen and a DNA polymerase δ auxiliary protein. Nature, 326:517-520.
92. Ranima, M., T.-G-. Tasy, M. Andujar, and A. Veis 1988 Localization of phosphoprotein in rat incisor dentin using immunocytochemical techniques. J. Histochem. Cytochem., 36:153-157.
93. Reith, E.J. 1970 The stages of amelogenesis as observed in molar teeth of young rats. J. Ultrastruct. Res., 30:111-151.
94. Robins, M.W. 1967 The proliferation of pulp cells in rat incisors. Archs. Oral Biol., 12:487-501.
95. Ruch, J. V. 1985a Odontoblast differentiation and the formation of the odontoblast layer. J. Dent. Res., 64:489-498.
96. Ruch, J.V. 1985b Epithelial-mesenchymal interactions in formation of mineralized tissues. In The Chemistry and Biology of Mineralized Tissues. N.T. Butler, ed. Ebsco Media, Birmingham, AL, 54-61.
97. Ruch, J.V. 1990 Patterned distribution of differentiating dental cells: Facts and hypotheses. J. Biol. Buccale, 18:91-98.
98. Ruderman, J., J. Westendorf, F. Luca, D. Beach, G. Draetta, and K. Swenson 1990 Cyclins and control of the cell cycle in early embryos. Dev. Biol., 37-45.
99. Sampson, S.A., H. Kreipe, C.E. Gillet, M.A. Chaudary, A. Khan, K. Wicks, R. Parwaresch, and D.M. Barnes 1992 KiS1-A novel monoclonal antibody which recognizes proliferating cells: Evaluation of its relationship to prognosis in mammary carcinoma. J. Pathol., 168:179-185.
100. Schutte, B., M.M.J. Reynders, F.T. Bosman, and G.H. Blijham 1987 Studies with anti-bromodeoxyuridine antibodies: II. Stimulaneous immunocytochemical detection of antigen expression and DNA synthesis by in vivo labeling of mouse intestinal mucosa. J. Histochem. Cytochem., 35:371-374.
101. 1 cyclin. Cell, 73:1059-1065.
102. Shibui, S., T. Hoshino, M. Vanderlaan, and J.W. Gray 1989 Double labeling with iodo- and bromodeoxyuridine for cell kinetics studies. J. Histochem. Cytochem., 37:1007-1011.
103. Slavkin, H.C., W. Mino, and P. Bringas 1976 The biosynthesis and secretion of precursor enamel protein by ameloblasts as visualized by autoradiography after tryptophan administration. Anat. Rec., 185:289-312.
104. Slavkin, H.C. 1978 The nature and nurture of epithelial-mesenchymal interactions during tooth morphogenesis. J. Biol. Buccale, 6:189-203.
105. Slavkin, H.C. 1988 Gene regulation in the development of oral tissues. J. Dent. Res., 67:1142-1149.
106. Slavkin, H.C. 1990 Molecular determinants of tooth development. Crit. Rev. Oral Biol. Med., 1:1-16.
107. 3H-thymidine. Anat. Rec., 183:523-562.
108. 3H-thymidine: The concept of a continuously differentiating cross-sectional segment. Am. J. Anat., 145:225-260.
109. Smith, C.E., and H. Warshawsky 1976b Quantitative analysis of cell turnover in the enamel organ of the rat incisor: Evidence for ameloblast death immediately after enamel matrix secretion. Anat. Rec., 187:63-98.
110. 3H-thymidine. Am. J. Anat., 158:321-343.
111. Snead, M.L., W. Luo, E.C. Lau, and H.C. Slavkin 1988 Spatial- and temporal-restricted pattern for amelogenin gene expression during mouse molar tooth organogenesis. Development, 104:77-85.
112. Sobczak-Thepot, J., F. Harper, Y. Florentin, F. Zindy, C. Brechot, and E. Puvion 1993 Localization of cyclin A at the sites of cellular DNA replication. Exp. Cell Res., 206:43-48.
113. Stallard, R.E., M.A. Diab, and H.A. Zander 1966 Kinetics of deoxyribonucleic acid synthesis within the inner enamel epithelium. J. Dent. Res., 45:315-322.
114. Starkey, W.E. 1963 The migration and renewal of tritium labelled cells in the developing enamel organ of rabbits. Br. Dent. J., 115:143-153.
115. Sveen, O.B., and R.R. Hawes 1968 Differentiation of new odontoblasts and dentine bridge formation in rat molar teeth after tooth grinding. Archs. Oral Biol., 13:1399-1412.
116. Tan, C.K., C. Castillo, A.G. So, and K.M. Downey 1986 An auxiliary protein for DNA polymerase δ from fetal calf thymus. J. Biol. Chem., 261:12310-12316.
117. Taylor, J.H., P.S. Woods, and W.L. Hughes 1957 The organization and duplication of chromosomes as revealed by autoradiographic studies using tritium-labeled thymidine. Proc. Natl. Acad. Sci. USA, 43:122-128.
118. Thesleff, I., and K. Hurmerinta 1981 Tissue interactions in tooth development. Differentiation, 18:75-88.
119. Thesleff, I, A.M. Partanen, and S. Vainio 1991a Epithelial-mesenchymal interactions in tooth morphogenesis: The roles of extracellular matrix, growth factors, and cell surface receptors. J. Craniofac. Genet. Dev. Biol., 11:229-237.
120. Thesleff, I., A. Vaahtokari, and S. Vainio 1991b Molecular changes during determination and differentiation of the dental mesenchymal cell lineage. J. Biol. Buccale, 18:179-188.
121. Todorov, I., R. Philipova, N. Zhelev, A. Hadjiolov 1988 Changes in a nuclear matrix antigen during the cell cycle: Interphase and mitotic cells. Biol. Cell, 62:105-110.
122. Toschi, L., and R. Bravo 1988 Changes in cyclin/proliferating cell nuclear antigen distribution during DNA repair synthesis. J. Cell Biol., 107:1623-1628.
123. Vaahtokari, A., S. Vainio, and I. Thesleff 1991 Associations between transforming growth factor β1 RNA expression and epithelial-mesenchymal interactions during tooth morphogenesis. Development, 113:985-994.
124. Vainio, S., M. Jaikanen, A. Vaahtokari, C. Sahlberg, M. Mali, M. Bernfield, and I. Thesleff 1991 Expression of syndecan gene is induced early, is transient, and correlates with changes in mesenchymal cell proliferation during tooth organogenesis. Dev. Biol., 147:322-333.
125. Vainio, S., and I. Thesleff 1992a Sequential induction of syndecan, tenascin and cell proliferation associated with mesenchymal cell condensation during early tooth development. Differentiation, 50:97-105.
126. Vainio, S., and I. Thesleff 1992b Coordinated induction of cell proliferation and syndecan expression in dental mesenchyme by epithelium: evidence for diffusible signals. Dev. Dynam., 194:105-117.
127. 14-labelled adenine and thymidine. Exp. Cell Res., 14:510-531.
128. Wang, E., and J. Krueger 1985 Application of a unique monoclonal antibody as a marker for nonproliferating subpopulations of cells of some tissue. J. Histochem. Cytochem., 33:587-594.
129. Wang, E., and G. Tomaszewski 1991 Granular presence of terminin is the marker to distinguish between the senescent and quiescent states. J. Cell. Physiol., 147:514-522.
130. Warshawsky, H., and C.E. Smith 1974 Morphological classification of rat incisor ameloblasts. Anat. Rec., 179:423-446.
131. Waseem, N.H., and D.P. Lane 1990 Monoclonal antibody analysis of the proliferating cell nuclear antigen (PCNA): Structural conservation and the detection of the nucleolar form. J. Cell Sci., 96: 121-129.
132. Weinstock, M., and C.P. Leblond 1973 Radioautographic visualization of the deposition of a phosphoprotein at the mineralization front in the dentin of the rat incisor. J. Cell Biol., 838-845.
133. Wilson, G.D., N.J. McNally, E. Dunphy, H. Karcher, and R. Pfranger 1985 The labelling index of human and mouse tumours assessed by bromodeoxyuridine staining in vitro and in vivo and flow cytometry. Cytometry, 6:641-647.
134. Yamamura, T. 1985 Differentiation of pulpal cells and inductive influences of various matrices with reference to pulpal wound healing. J. Dent, Res., 64:530-540.
135. Yanagida, M., N. Kinoshita, E.M. Stone, and H. Yamano 1992 Protein phosphatases and cell division cycle control. In: Regulation of the Eukaryotic Cell Cycle. J. Marsch, ed. John Wiley & Sons, Chichester, pp. 130-140.
136. Young, W.G., C.Z. Zhang, H. Li, P.E. Lobie, and M.J. Waters 1993 A bromodeoxyuridine immunocytochemical and morphometric study of the influence of growth hormone on cell proliferation in odontogenic mesenchyme of the Lewis Dwarf rat. Archs. Oral Biol., 38:207-214.
137. Zajicek, G., and M. Bar-Lev 1971a Kinetics of the inner enamel epithelium in the adult rat incisor: I. Experimental results. Cell Tissue Kinet., 4:155-162.
138. Zajicek, G., and M. Bar-Lev 1971b Kinetics of the inner enamel epithelium in the adult rat incisor: II. Computer Model. Cell Tissue Kinet., 4:163-170.
139. Zajicek, G., Y. Michaeli, and M.M. Weinreb 1972 Kinetics of the inner enamel epithelium in the adult rat incisor during accelerated eruption. Cell Tissue Kinet., 5:35-39.