Correlation between human cytomegalovirus quantitative p72 antigenemia and viremia

Clinical and Diagnostic Virology

Volumn 7, Issue 1, 1996, Pages 63-67

  Reina, Jordi ^a   Blanco, Isabel ^a   Munar, Maria ^a  

^a UNIVERSITAT DE LES ILLES BALEARS   (Spain)

Author keywords

Antigenemia; Human cytomegalovirus; p72 antigen; pp65 antigen; Quantitative shell vial culture

Indexed keywords

MONOCLONAL ANTIBODY; VIRUS ANTIGEN;

ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; HUMAN; PRIORITY JOURNAL; VIRUS CULTURE; VIRUS PARTICLE; VIRUS REPLICATION;

ANTIBODIES, MONOCLONAL; ANTIBODIES, VIRAL; ANTIGENS, VIRAL; CELL LINE; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; HUMANS; IMMEDIATE-EARLY PROTEINS; PHOSPHOPROTEINS; PROSPECTIVE STUDIES; VIRAL MATRIX PROTEINS; VIREMIA;

CYTOMEGALOVIRUS; HUMAN HERPESVIRUS 5;

EID: 0029951199     PISSN: 09280197     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-0197(96)00249-8     Document Type: Article

References (13)

1. Boeckh, M., Bowden R.A., Goodrich. J.M., Pettinger, M. and Meyers, J.D. (1992) Cytomegalovirus antigen detection in peripheral blood leukocytes after allogeneic marrow transplantation. Blood 80, 1358-1364.
2. Buller, R.S., Bailey, T.C., Ettinger, N.A., Keener, M., Langlois, T., Miller, J.P. and Storch, G.A. (1992) Use of a modified shell vial technique to quantitate cytomegalovirus viremia in a population of solid-organ transplant recipients. J. Clin. Microbiol. 30. 2620-2624.
3. Erice, A., Holm, M.A., Gill, P.C., Henry S., Dirksen, C.L., Dunn, D.L., Hillam, R.P. and Balfour, Jr., H.H., (1992) Cytomegalovirus (CMV) antigenemia assay is more sensitive than shell vial cultures for rapid detection of CMV in polymorphonuclear blood leukocytes. J. Clin. Microbiol. 30, 2822-2825.
4. Gerna, G., Revello, M.G., Percivalle, E., Zavattoni, M., Parea, M. and Battaglia, M. (1990) Quantification of human cytomegalovirus viremia by using monoclonal antibodies to different viral proteins. J. Clin. Microbiol. 28, 2681-2688.
5. Gerna, G., Zipeto, D., Percivalle, E., Parea. M., Revello, M.G., Maccario, R., Peri, G. and Milanesi, G. (1992a) Human cytomegalovirus infection of the major leukocyte subpopulations and evidence for initial viral replication in polymorphonuclear leukocytes from viremic patients. J. Infect. Dis. 166, 1236-1244.
6. Gerna, G., Revello, M.G., Percivalle, E. and Morini, F. (1992b) Comparison of different immunostaining techniques and monoclonal antibodies to the lower matrix phosphoprotein (pp65) for optimal quantitation of human cytomegalovirus antigenemia. J. Clin. Microbiol. 30, 1232-1237.
7. Gerna. G., Percivalle, E., Revello, M.G. and Morini, F. (1993) Correlation of quantitative human cytomegalovirus pp65-, p72-and p150-antigenemia, viremia, and circulating endothelial giant cells with clinical symptoms and antiviral treatment in immunocompromised patients. Clin. Diagn. Virol. 1, 47-59.
8. Jacobson, M.A. and Mills, J. (1988) Serious cytomegalovirus disease in the acquired immunodeficiency syndrome (AIDS). Clinical finding, diagnosis, and treatment. Ann. Intern. Med. 108. 585-594.
9. Landry, M.L. and Ferguson, D. (1993) Comparison of quantitative cytomegalovirus antigenemia assay with culture methods and correlation with clinical disease. J. Clin. Microbiol. 31, 2851-2856.
10. Rubin, R.H. (1988) Infection in the renal and liver transplant patient. In: R.H. Rubin and L.S. Young (Eds.), Clinical Approach to Infection in the Compromised Host, 2nd edn., Plenum, New York, pp. 557-621.
11. Storch, G.A., Buller, R.S., Bailey, T.C., Ettinger, N.A., Langlois, T., Gaudreault-Keener, M. and Welby, P.L. (1994) Comparison of PCR and pp65 antigenemia assay with quantitative shell vial culture for detection of cytomegalovirus in blood leukocytes from solid-organ transplant recipients. J. Clin. Microbiol. 32, 997-1003.
12. van der Bij, W., Schirm, J., Torensma, R., van Son, W.J., Tegzess, A.M. and The, T.H. (1988a) Comparison between viremia and antigenemia for detection of cytomegalovirus in blood. J. Clin. Microbiol. 26, 2531-2535.
13. van der Bij, W., Torensma, R., van Son, W.J., Anema, J., Schrim, J., Tegzess, A.M. and The, T.H. (1988b) Rapid immunodiagnosis of active cytomegalovirus infection by monoclonal antibody staining of blood leukocytes. J. Med. Virol. 25, 179-188.