-
4
-
-
0023116834
-
Prevalence of Alzheimer's disease in a retirement community
-
Pfeffer RI, Afifi AA, Chance JM. Prevalence of Alzheimer's disease in a retirement community. Am J Epidemiol. 1987; 125:420-36.
-
(1987)
Am J Epidemiol.
, vol.125
, pp. 420-436
-
-
Pfeffer, R.I.1
Afifi, A.A.2
Chance, J.M.3
-
5
-
-
0024317904
-
Prevalence of Alzheimer's disease in a community population of older persons
-
Evans DA, Funkenstein HH, Albert MS et al. Prevalence of Alzheimer's disease in a community population of older persons. JAMA. 1989; 262:2551-6.
-
(1989)
JAMA
, vol.262
, pp. 2551-2556
-
-
Evans, D.A.1
Funkenstein, H.H.2
Albert, M.S.3
-
7
-
-
0028365785
-
The natural history of Alzheimer's disease: Description of cohort and accuracy of diagnosis
-
Becker JT, Boller F, Lopez OL et al. The natural history of Alzheimer's disease: description of cohort and accuracy of diagnosis. Arch Neurol. 1994; 51:585-94.
-
(1994)
Arch Neurol.
, vol.51
, pp. 585-594
-
-
Becker, J.T.1
Boller, F.2
Lopez, O.L.3
-
8
-
-
0028239996
-
Neuropsychology and Alzheimer's disease
-
Koss E. Neuropsychology and Alzheimer's disease. Clin Geriatr Med. 1994; 10:299-313.
-
(1994)
Clin Geriatr Med.
, vol.10
, pp. 299-313
-
-
Koss, E.1
-
9
-
-
0026469523
-
Detection in life of confirmed Alzheimer's disease using a simple measurement of medial temporal lobe atrophy by computerized tomography
-
Jobst KA, Smith AD, Szatmari M et al. Detection in life of confirmed Alzheimer's disease using a simple measurement of medial temporal lobe atrophy by computerized tomography. Lancet. 1992; 340:1179-83.
-
(1992)
Lancet
, vol.340
, pp. 1179-1183
-
-
Jobst, K.A.1
Smith, A.D.2
Szatmari, M.3
-
10
-
-
0028269935
-
Rapidly progressing atrophy of medial temporal lobe in Alzheimer's disease
-
Jobst KA, Smith AD, Szatmari M et al. Rapidly progressing atrophy of medial temporal lobe in Alzheimer's disease. Lancet. 1994; 343:829-30.
-
(1994)
Lancet
, vol.343
, pp. 829-830
-
-
Jobst, K.A.1
Smith, A.D.2
Szatmari, M.3
-
11
-
-
0021271971
-
Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of the Department of Health and Human Services Task Force on Alzheimer's Disease
-
McKhann G, Drachman D, Holstein M et al. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of the Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984; 34:939-44.
-
(1984)
Neurology
, vol.34
, pp. 939-944
-
-
McKhann, G.1
Drachman, D.2
Holstein, M.3
-
12
-
-
0016823810
-
Mini-Mental State: A practical method for grading the cognitive state of patients for clinicians
-
Folstein M, Folstein S, McHugh PR et al. Mini-Mental State: a practical method for grading the cognitive state of patients for clinicians. J Psychiatr Res. 1975; 12:189-98.
-
(1975)
J Psychiatr Res.
, vol.12
, pp. 189-198
-
-
Folstein, M.1
Folstein, S.2
McHugh, P.R.3
-
13
-
-
0026023082
-
Detection of abnormal memory declines in mild cases of Alzheimer's disease using CERAD neuropsychological measures
-
Welsh K, Butters N, Hughes J et al. Detection of abnormal memory declines in mild cases of Alzheimer's disease using CERAD neuropsychological measures. Arch Neurol. 1991; 48:278-81.
-
(1991)
Arch Neurol.
, vol.48
, pp. 278-281
-
-
Welsh, K.1
Butters, N.2
Hughes, J.3
-
14
-
-
0025105238
-
Immunoelectron microscopic localization of amyloid-β protein in the diffuse plaques of Alzheimer-type dementia
-
Yamaguchi H, Nakazato Y, Hirai S et al. Immunoelectron microscopic localization of amyloid-β protein in the diffuse plaques of Alzheimer-type dementia. Brain Res. 1990; 508:320-4.
-
(1990)
Brain Res.
, vol.508
, pp. 320-324
-
-
Yamaguchi, H.1
Nakazato, Y.2
Hirai, S.3
-
15
-
-
0027410176
-
βA4 deposits are constant in the brain of the oldest old: An immunocytochemical study of 20 French centenarians
-
Delaère P, He Y, Fayet G et al. βA4 deposits are constant in the brain of the oldest old: an immunocytochemical study of 20 French centenarians. Neurobiol Aging. 1993; 14:191-4.
-
(1993)
Neurobiol Aging
, vol.14
, pp. 191-194
-
-
Delaère, P.1
He, Y.2
Fayet, G.3
-
16
-
-
0021207461
-
Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein
-
Glenner GG, Wong CW. Alzheimer's disease and Down's syndrome: sharing of a unique cerebrovascular amyloid fibril protein. Biochem Biophys Res Commun. 1984; 122:1131-5.
-
(1984)
Biochem Biophys Res Commun.
, vol.122
, pp. 1131-1135
-
-
Glenner, G.G.1
Wong, C.W.2
-
17
-
-
0026567936
-
Amyloidogenesis in Alzheimer's disease: Some possible therapeutic opportunities
-
Gandy S, Greengard P. Amyloidogenesis in Alzheimer's disease: some possible therapeutic opportunities. Trends Pharmacol Sci. 1992; 13:108-13.
-
(1992)
Trends Pharmacol Sci.
, vol.13
, pp. 108-113
-
-
Gandy, S.1
Greengard, P.2
-
18
-
-
0025899041
-
Amyloid deposition as the central event in the aetiology of Alzheimer's disease
-
Hardy J, Allsop D. Amyloid deposition as the central event in the aetiology of Alzheimer's disease. Trends Pharmacol Sci. 1991; 12:383-8.
-
(1991)
Trends Pharmacol Sci.
, vol.12
, pp. 383-388
-
-
Hardy, J.1
Allsop, D.2
-
20
-
-
0028985574
-
Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein
-
Games D, Adams D, Alessandrini R et al. Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein. Nature. 1995; 373:523-7.
-
(1995)
Nature
, vol.373
, pp. 523-527
-
-
Games, D.1
Adams, D.2
Alessandrini, R.3
-
21
-
-
0027526419
-
Release of excess amyloid β protein from a mutant amyloid β protein precursor
-
Cai X-D, Golde TE, Younkin SG. Release of excess amyloid β protein from a mutant amyloid β protein precursor. Science. 1993; 259:514-6.
-
(1993)
Science
, vol.259
, pp. 514-516
-
-
Cai, X.-D.1
Golde, T.E.2
Younkin, S.G.3
-
22
-
-
0025733411
-
Aggregation-related toxicity of synthetic β-amyloid protein in hippocampal cultures
-
Pike CJ, Walencewicz AJ, Glabe CG et al. Aggregation-related toxicity of synthetic β-amyloid protein in hippocampal cultures. Eur J Pharmacol. 1991; 207:367-8.
-
(1991)
Eur J Pharmacol.
, vol.207
, pp. 367-368
-
-
Pike, C.J.1
Walencewicz, A.J.2
Glabe, C.G.3
-
23
-
-
0027257708
-
Apoptosis is induced by β-amyloid in cultured central nervous system neurons
-
Loo DT, Copani A, Pike CJ et al. Apoptosis is induced by β-amyloid in cultured central nervous system neurons. Proc Natl Acad Sci U S A. 1993; 90:7951-5.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 7951-7955
-
-
Loo, D.T.1
Copani, A.2
Pike, C.J.3
-
24
-
-
0026570528
-
β-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity
-
Mattson MP, Cheng B, Davis D et al. β-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J Neurosci. 1992; 12:376-89.
-
(1992)
J Neurosci.
, vol.12
, pp. 376-389
-
-
Mattson, M.P.1
Cheng, B.2
Davis, D.3
-
25
-
-
0025987048
-
Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment
-
Terry RD, Masliah E, Salmon DP et al. Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment. Ann Neurol. 1991; 30:572-80.
-
(1991)
Ann Neurol.
, vol.30
, pp. 572-580
-
-
Terry, R.D.1
Masliah, E.2
Salmon, D.P.3
-
26
-
-
0028172886
-
β-Amyloid neurotoxicity requires fibril formation and is inhibited by Congo red
-
Lorenzo A, Yankner BA. β-Amyloid neurotoxicity requires fibril formation and is inhibited by Congo red. Proc Natl Acad Sci U S A. 1994; 91:12243-7.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 12243-12247
-
-
Lorenzo, A.1
Yankner, B.A.2
-
27
-
-
0028972701
-
Image-analysis of β-amyloid load in Alzheimer's disease and relation to dementia severity
-
Cummings BJ, Cotman CW. Image-analysis of β-amyloid load in Alzheimer's disease and relation to dementia severity. Lancet. 1995; 346:1524-8.
-
(1995)
Lancet
, vol.346
, pp. 1524-1528
-
-
Cummings, B.J.1
Cotman, C.W.2
-
28
-
-
0026101636
-
Aggregation and secondary structure of synthetic amyloid βA4 peptides of Alzheimer's disease
-
Hilbich C, Kisters-Woike B, Reed J et al. Aggregation and secondary structure of synthetic amyloid βA4 peptides of Alzheimer's disease. J Mol Biol. 1991; 218:149-63.
-
(1991)
J Mol Biol.
, vol.218
, pp. 149-163
-
-
Hilbich, C.1
Kisters-Woike, B.2
Reed, J.3
-
30
-
-
0028176153
-
Role of the β-amyloid precursor protein in Alzheimer's disease
-
Ashall F, Goate AM. Role of the β-amyloid precursor protein in Alzheimer's disease. Trends Biochem. 1994; 19:42-5.
-
(1994)
Trends Biochem.
, vol.19
, pp. 42-45
-
-
Ashall, F.1
Goate, A.M.2
-
31
-
-
0027367764
-
Physiological production of the β-amyloid protein and the mechanism of Alzheimer's disease
-
Selkoe DJ. Physiological production of the β-amyloid protein and the mechanism of Alzheimer's disease. Trends Neurosci. 1993; 16:403-8.
-
(1993)
Trends Neurosci.
, vol.16
, pp. 403-408
-
-
Selkoe, D.J.1
-
32
-
-
0025295039
-
Cleavage of amyloid-β peptide during constitutive processing of its precursor
-
Esch FS, Keim PS, Beattie EC et al. Cleavage of amyloid-β peptide during constitutive processing of its precursor. Science. 1990; 248:1122-4.
-
(1990)
Science
, vol.248
, pp. 1122-1124
-
-
Esch, F.S.1
Keim, P.S.2
Beattie, E.C.3
-
33
-
-
0029108154
-
Specificity of the Alzheimer's amyloid precursor protein α-secretase
-
Hooper NM, Turner AJ. Specificity of the Alzheimer's amyloid precursor protein α-secretase. Trends Biochem. 1995; 20:15-6.
-
(1995)
Trends Biochem.
, vol.20
, pp. 15-16
-
-
Hooper, N.M.1
Turner, A.J.2
-
34
-
-
0026735070
-
Targeting of cell-surface β-amyloid precursor protein to lysosomes: Alternative processing into amyloid-bearing fragments
-
Haass C, Koo EH, Mellon A et al. Targeting of cell-surface β-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments. Nature. 1992; 357: 500-2.
-
(1992)
Nature
, vol.357
, pp. 500-502
-
-
Haass, C.1
Koo, E.H.2
Mellon, A.3
-
35
-
-
0026589836
-
Chloroquine inhibits intracellular degradation but not secretion of Alzheimer β/A4 amyloid precursor protein
-
Caporaso G, Gandy SE, Buxbaum JD et al. Chloroquine inhibits intracellular degradation but not secretion of Alzheimer β/A4 amyloid precursor protein. Proc Natl Acad Sci U S A. 1992; 89:2252-6.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 2252-2256
-
-
Caporaso, G.1
Gandy, S.E.2
Buxbaum, J.D.3
-
36
-
-
0027459686
-
Secretion of β-amyloid precursor protein cleaved at the amino terminus of the β-amyloid peptide
-
Seubert P, Oltersdorf T, Lee MG et al. Secretion of β-amyloid precursor protein cleaved at the amino terminus of the β-amyloid peptide. Nature. 1993; 361:260-3.
-
(1993)
Nature
, vol.361
, pp. 260-263
-
-
Seubert, P.1
Oltersdorf, T.2
Lee, M.G.3
-
37
-
-
0026646605
-
Isolation and quantification of soluble Alzheimer's β-peptide from biological fluids
-
Seubert P, Vigo-Pelfrey C, Esch F et al. Isolation and quantification of soluble Alzheimer's β-peptide from biological fluids. Nature. 1992; 359:325-7.
-
(1992)
Nature
, vol.359
, pp. 325-327
-
-
Seubert, P.1
Vigo-Pelfrey, C.2
Esch, F.3
-
38
-
-
0027435535
-
Protein phosphorylation inhibits production of Alzheimer amyloidβ/A4 peptide
-
Buxbaum JD, Koo EH, Greengard P. Protein phosphorylation inhibits production of Alzheimer amyloidβ/A4 peptide. Proc Natl Acad Sci U S A. 1993; 90:9195-8.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 9195-9198
-
-
Buxbaum, J.D.1
Koo, E.H.2
Greengard, P.3
-
39
-
-
0026448114
-
Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer β/A4 amyloid precursor protein
-
Buxbaum JD, Oishi M, Chen HI et al. Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer β/A4 amyloid precursor protein. Proc Natl Acad Sci U S A. 1992; 89:10075-8.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 10075-10078
-
-
Buxbaum, J.D.1
Oishi, M.2
Chen, H.I.3
-
40
-
-
0026476297
-
Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors
-
Nitsch RM, Slack BE, Wurtman RJ et al. Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors. Science. 1992; 258:304-7.
-
(1992)
Science
, vol.258
, pp. 304-307
-
-
Nitsch, R.M.1
Slack, B.E.2
Wurtman, R.J.3
-
41
-
-
0028207004
-
Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner
-
Buxbaum JD, Ruefli AA, Parker CA et al. Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner. Proc Natl Acad Sci US A. 1994; 91:4489-93.
-
(1994)
Proc Natl Acad Sci US A
, vol.91
, pp. 4489-4493
-
-
Buxbaum, J.D.1
Ruefli, A.A.2
Parker, C.A.3
-
42
-
-
0028342424
-
Estrogen regulates metabolism of Alzheimer amyloid β precursor protein
-
Jaffe AB, Toran-Allerand CD, Greengard P et al. Estrogen regulates metabolism of Alzheimer amyloid β precursor protein. J Biol Chem. 1994; 269:13065-8.
-
(1994)
J Biol Chem.
, vol.269
, pp. 13065-13068
-
-
Jaffe, A.B.1
Toran-Allerand, C.D.2
Greengard, P.3
-
43
-
-
0029004341
-
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
-
Sherrington R, Rogaev EI, Liang Y et al. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature. 1995; 375:754-60.
-
(1995)
Nature
, vol.375
, pp. 754-760
-
-
Sherrington, R.1
Rogaev, E.I.2
Liang, Y.3
-
44
-
-
0029087026
-
Candidate gene for the chromosome 1 familial Alzheimer's disease locus
-
Levy-Lahad E, Wasco W, Poorkaj P et al. Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science. 1995; 269:973-7.
-
(1995)
Science
, vol.269
, pp. 973-977
-
-
Levy-Lahad, E.1
Wasco, W.2
Poorkaj, P.3
-
45
-
-
0028985061
-
β-Amyloid peptide produced in vitro is degraded by proteinases released by cultured cells
-
Naidu A, Quon D, Cordell B. β-Amyloid peptide produced in vitro is degraded by proteinases released by cultured cells. J Biol Chem. 1995; 270:1369-74.
-
(1995)
J Biol Chem.
, vol.270
, pp. 1369-1374
-
-
Naidu, A.1
Quon, D.2
Cordell, B.3
-
46
-
-
0027420369
-
Tau protein and the neurofibrillary pathology of Alzheimer's disease
-
Goedert M. Tau protein and the neurofibrillary pathology of Alzheimer's disease. Trends Neurosci. 1993; 16:460-5.
-
(1993)
Trends Neurosci.
, vol.16
, pp. 460-465
-
-
Goedert, M.1
-
47
-
-
0027407246
-
The molecular and cellular biology of tau
-
Koski KS. The molecular and cellular biology of tau. Brain Pathol. 1993; 3:39-43.
-
(1993)
Brain Pathol.
, vol.3
, pp. 39-43
-
-
Koski, K.S.1
-
48
-
-
0027217679
-
The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development
-
Goedert M, Jakes R, Crowther RA et al. The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development. Proc Natl Acad Sci U S A. 1993; 90:5066-70.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 5066-5070
-
-
Goedert, M.1
Jakes, R.2
Crowther, R.A.3
-
49
-
-
0028179001
-
Secreted β-amyloid precursor protein stimulates mitogen-activated protein kinase and enhances tau phosphorylation
-
Greenberg SM, Koo EH, Selkoe DJ et al. Secreted β-amyloid precursor protein stimulates mitogen-activated protein kinase and enhances tau phosphorylation. Proc Natl Acad Sci U S A. 1994; 91:7104-8.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 7104-7108
-
-
Greenberg, S.M.1
Koo, E.H.2
Selkoe, D.J.3
-
50
-
-
0027945346
-
Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau
-
Matsuo ES, Shin R-W, Billingsley ML et al. Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau. Neuron. 1994; 13:989-1002.
-
(1994)
Neuron.
, vol.13
, pp. 989-1002
-
-
Matsuo, E.S.1
Shin, R.-W.2
Billingsley, M.L.3
-
51
-
-
0024299370
-
Cholesterol transport protein with expanding role in cell biology
-
Mahley RW. Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science. 1988; 240:622-9.
-
(1988)
Science
, vol.240
, pp. 622-629
-
-
Mahley, R.W.1
Apolipoprotein, E.2
-
52
-
-
0025971426
-
Apolipoprotein e immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease
-
Nambia Y, Tomonaga M, Kawasaki H et al. Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease. Brain Res. 1991; 541:163-6.
-
(1991)
Brain Res.
, vol.541
, pp. 163-166
-
-
Nambia, Y.1
Tomonaga, M.2
Kawasaki, H.3
-
53
-
-
0027407565
-
Apolipo-protein E: High-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
-
Strittmatter WJ, Saunders AM, Schmechel D et al. Apolipo-protein E: high-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci U S A. 1993; 90:1977-81.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 1977-1981
-
-
Strittmatter, W.J.1
Saunders, A.M.2
Schmechel, D.3
-
54
-
-
0025735884
-
Linkage studies in familial Alzheimer disease: Evidence for chromosome 19 linkage
-
Pericak-Vance MA, Bebout JL, Gaskell PC Jr et al. Linkage studies in familial Alzheimer disease: evidence for chromosome 19 linkage. Am J Hum Genet. 1991; 48:1034-50.
-
(1991)
Am J Hum Genet.
, vol.48
, pp. 1034-1050
-
-
Pericak-Vance, M.A.1
Bebout, J.L.2
Gaskell Jr., P.C.3
-
55
-
-
0026718601
-
The role of apolipoprotein E genetic variants in lipoprotein disorders
-
Rall SC, Mahley RW. The role of apolipoprotein E genetic variants in lipoprotein disorders. J Intern Med. 1992; 231:653-9.
-
(1992)
J Intern Med.
, vol.231
, pp. 653-659
-
-
Rall, S.C.1
Mahley, R.W.2
-
56
-
-
0027282035
-
Apolipoprotein E polymorphism and Alzheimer's disease
-
Poirer J, Davignon J, Bouthillier D et al. Apolipoprotein E polymorphism and Alzheimer's disease. Lancet. 1993; 342:697-9.
-
(1993)
Lancet
, vol.342
, pp. 697-699
-
-
Poirer, J.1
Davignon, J.2
Bouthillier, D.3
-
57
-
-
0027203749
-
Apolipoprotein e geno-type and Alzheimer's disease
-
Letter
-
Noguchi S, Murakami K, Yamada N. Apolipoprotein E geno-type and Alzheimer's disease. Lancet. 1993; 342:737. Letter.
-
(1993)
Lancet
, vol.342
, pp. 737
-
-
Noguchi, S.1
Murakami, K.2
Yamada, N.3
-
58
-
-
0027919960
-
Apolipoprotein e geno-type and Alzheimer's disease
-
Letter
-
Payami H, Kaye J, Heston LL et al. Apolipoprotein E geno-type and Alzheimer's disease. Lancet. 1993; 342:738. Letter.
-
(1993)
Lancet
, vol.342
, pp. 738
-
-
Payami, H.1
Kaye, J.2
Heston, L.L.3
-
59
-
-
0028841027
-
Apolipoprotein E, dementia, and cortical deposition of β-amyloid protein
-
Polvikoski T, Sulkava R, Haltia M et al. Apolipoprotein E, dementia, and cortical deposition of β-amyloid protein. N Engl J Med. 1995; 333:1242-7.
-
(1995)
N Engl J Med.
, vol.333
, pp. 1242-1247
-
-
Polvikoski, T.1
Sulkava, R.2
Haltia, M.3
-
60
-
-
0027194791
-
Gene dose of apolipoprotein e type 4 allele and the risk of Alzheimer's disease in late onset families
-
Corder EH, Saunders AM, Strittmatter WJ et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science. 1993; 261:921-3.
-
(1993)
Science
, vol.261
, pp. 921-923
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmatter, W.J.3
-
61
-
-
0028051339
-
Senile dementia of the Lewy body type has an apolipoprotein E/ε4 allele frequency intermediate between controls and Alzheimer's disease
-
Hardy J, Crook R, Prihar G et al. Senile dementia of the Lewy body type has an apolipoprotein E/ε4 allele frequency intermediate between controls and Alzheimer's disease. Neurosci Lett. 1994; 182:1-2.
-
(1994)
Neurosci Lett.
, vol.182
, pp. 1-2
-
-
Hardy, J.1
Crook, R.2
Prihar, G.3
-
62
-
-
0028316441
-
ApoE genotype and Down's syndrome
-
Hardy J, Crook R, Perry R et al. ApoE genotype and Down's syndrome. Lancet. 1994; 343:979-80.
-
(1994)
Lancet
, vol.343
, pp. 979-980
-
-
Hardy, J.1
Crook, R.2
Perry, R.3
-
64
-
-
0028172930
-
Apolipoprotein E in animal models of CNS injury and in Alzheimer's disease
-
Poirer J. Apolipoprotein E in animal models of CNS injury and in Alzheimer's disease. Trends Neurosci. 1994; 17:525-30.
-
(1994)
Trends Neurosci.
, vol.17
, pp. 525-530
-
-
Poirer, J.1
-
65
-
-
12044254746
-
Binding of human apolipoprotein e to synthetic amyloid β peptide: Isoform-specific effects and implications for late-onset Alzheimer disease
-
Strittmatter WJ, Weisgraber KH, Huang DY et al. Binding of human apolipoprotein E to synthetic amyloid β peptide: isoform-specific effects and implications for late-onset Alzheimer disease. Proc Natl Acad Sci U S A. 1993; 90:8098-102.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 8098-8102
-
-
Strittmatter, W.J.1
Weisgraber, K.H.2
Huang, D.Y.3
-
66
-
-
0027365822
-
Increased amyloid β peptide deposition in cerebral cortex as a consequence of apolipoprotein e genotype in late-onset Alzheimer's disease
-
Schmechel DE, Saunders AM, Strittmatter WJ et al. Increased amyloid β peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer's disease. Proc Natl Acad Sci U S A. 1993; 90:9649-53.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 9649-9653
-
-
Schmechel, D.E.1
Saunders, A.M.2
Strittmatter, W.J.3
-
67
-
-
0028035306
-
Isoform-specific interactions of apolipoprotein e with microtubule-associated protein tau: Implications for Alzheimer's disease
-
Strittmatter WJ, Saunders AM, Goedert M et al. Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer's disease. Proc Natl Acad Sci U S A. 1994; 91:11183-6.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 11183-11186
-
-
Strittmatter, W.J.1
Saunders, A.M.2
Goedert, M.3
-
68
-
-
0028033804
-
Isoform-specific interactions of apolipoprotein e with the microtubule-associated protein MAP2c: Implications for Alzheimer's disease
-
Huang DY, Goedert M, Jakes R et al. Isoform-specific interactions of apolipoprotein E with the microtubule-associated protein MAP2c: implications for Alzheimer's disease. Neurosci Lett. 1994; 182:55-8.
-
(1994)
Neurosci Lett.
, vol.182
, pp. 55-58
-
-
Huang, D.Y.1
Goedert, M.2
Jakes, R.3
-
69
-
-
0028018114
-
Apolipoprotein E is present in hippocampal neurons without neurofibrillary tangles in Alzheimer's disease and in age-matched controls
-
Han S-H, Hulette C, Saunders AM et al. Apolipoprotein E is present in hippocampal neurons without neurofibrillary tangles in Alzheimer's disease and in age-matched controls. Exp Neurol. 1994; 128:13-26.
-
(1994)
Exp Neurol.
, vol.128
, pp. 13-26
-
-
Han, S.-H.1
Hulette, C.2
Saunders, A.M.3
-
70
-
-
0028269666
-
Hypothesis: Microtuble instability and paired helical filament formation in the Alzheimer disease are related to apolipoprotein E genotype
-
Strittmatter WJ, Weisgraber KH, Goedert M et al. Hypothesis: microtuble instability and paired helical filament formation in the Alzheimer disease are related to apolipoprotein E genotype. Exp Neurol. 1994; 125:163-71.
-
(1994)
Exp Neurol.
, vol.125
, pp. 163-171
-
-
Strittmatter, W.J.1
Weisgraber, K.H.2
Goedert, M.3
-
71
-
-
0028232662
-
Differential effects of apolipoprotein E3 and E4 on neuronal growth in vitro
-
Nathan BP, Bellosta S, Sanan DA et al. Differential effects of apolipoprotein E3 and E4 on neuronal growth in vitro. Science. 1994; 264:850-2.
-
(1994)
Science
, vol.264
, pp. 850-852
-
-
Nathan, B.P.1
Bellosta, S.2
Sanan, D.A.3
-
72
-
-
0028889485
-
Statement on the use of apolipoprotein e testing for Alzheimer's disease
-
Farrer LA, Brin MF, Elsas L et al. Statement on the use of apolipoprotein E testing for Alzheimer's disease. JAMA. 1995; 274:1627-9.
-
(1995)
JAMA
, vol.274
, pp. 1627-1629
-
-
Farrer, L.A.1
Brin, M.F.2
Elsas, L.3
-
73
-
-
0028950856
-
Apolipoprotein E type 4 allele and cerebral glucose metabolism in relatives at risk for familial Alzheimer disease
-
Small GW, Mazziotta JC, Collins MT et al. Apolipoprotein E type 4 allele and cerebral glucose metabolism in relatives at risk for familial Alzheimer disease. JAMA. 1995; 273:942-7.
-
(1995)
JAMA
, vol.273
, pp. 942-947
-
-
Small, G.W.1
Mazziotta, J.C.2
Collins, M.T.3
-
76
-
-
0026486230
-
Increased cognitive sensitivity to scopolamine with age and a perspective on the scopolamine model
-
Molchan SE, Martinez RA, Hill JL et al. Increased cognitive sensitivity to scopolamine with age and a perspective on the scopolamine model. Brain Res Rev. 1992; 17:215-26.
-
(1992)
Brain Res Rev.
, vol.17
, pp. 215-226
-
-
Molchan, S.E.1
Martinez, R.A.2
Hill, J.L.3
-
78
-
-
0027938026
-
A potential noninvasive neurobiological test for Alzheimer's disease
-
Scinto LFM, Daffner KR, Dressier D et al. A potential noninvasive neurobiological test for Alzheimer's disease. Science. 1994; 266:1051-4.
-
(1994)
Science
, vol.266
, pp. 1051-1054
-
-
Scinto, L.F.M.1
Daffner, K.R.2
Dressier, D.3
-
79
-
-
0028921289
-
Detecting Alzheimer disease
-
Letter
-
Marx JL, Kumar SR, Thach AB et al. Detecting Alzheimer disease. Science. 1995; 267:1577. Letter.
-
(1995)
Science
, vol.267
, pp. 1577
-
-
Marx, J.L.1
Kumar, S.R.2
Thach, A.B.3
-
80
-
-
0026756286
-
A double-blind, placebo-controlled multicenter study of tacrine for Alzheimer's disease
-
Davis KL, Thal LJ, Gamzu ER et al. A double-blind, placebo-controlled multicenter study of tacrine for Alzheimer's disease. N Engl J Med. 1992; 327:1253-9.
-
(1992)
N Engl J Med.
, vol.327
, pp. 1253-1259
-
-
Davis, K.L.1
Thal, L.J.2
Gamzu, E.R.3
-
81
-
-
0028270519
-
A 30-week randomized controlled trial of high-dose tacrine in patients with Alzheimer's disease
-
Knapp MJ, Knopman DS, Solomon PR et al. A 30-week randomized controlled trial of high-dose tacrine in patients with Alzheimer's disease. JAMA. 1994; 271:985-91.
-
(1994)
JAMA
, vol.271
, pp. 985-991
-
-
Knapp, M.J.1
Knopman, D.S.2
Solomon, P.R.3
-
82
-
-
0029143531
-
Effectiveness and safety of velnacrine for the treatment of Alzheimer's disease
-
Antuono PG. Effectiveness and safety of velnacrine for the treatment of Alzheimer's disease. Arch Intern Med. 1995; 155:1766-72.
-
(1995)
Arch Intern Med.
, vol.155
, pp. 1766-1772
-
-
Antuono, P.G.1
-
83
-
-
0029151920
-
Caregiver time use. An outcome measure in clinical trial research on Alzheimer's disease
-
Clipp EC, Moore MJ. Caregiver time use. An outcome measure in clinical trial research on Alzheimer's disease. Clin Pharmacol Ther. 1995; 58:228-36.
-
(1995)
Clin Pharmacol Ther.
, vol.58
, pp. 228-236
-
-
Clipp, E.C.1
Moore, M.J.2
-
84
-
-
0029101130
-
Clinical pharmacokinetics of drugs for Alzheimer's disease
-
Parnetti L. Clinical pharmacokinetics of drugs for Alzheimer's disease. Clin Pharmacokinet. 1995; 29:110-29.
-
(1995)
Clin Pharmacokinet.
, vol.29
, pp. 110-129
-
-
Parnetti, L.1
-
85
-
-
0023049733
-
Anticholinesterase activity of a new carbamate, heptylphysostigmine, in view of its use in patients with Alzheimer-type dementia
-
Brufani M, Marta M, Pomponi M. Anticholinesterase activity of a new carbamate, heptylphysostigmine, in view of its use in patients with Alzheimer-type dementia. Eur J Biochem. 1986; 157:115-20.
-
(1986)
Eur J Biochem.
, vol.157
, pp. 115-120
-
-
Brufani, M.1
Marta, M.2
Pomponi, M.3
-
86
-
-
0028924664
-
Differential regulation of molecular subtypes of muscarinic receptors in Alzheimer's disease
-
Flynn DD, Ferrari-DiLeo G, Mash DC et al. Differential regulation of molecular subtypes of muscarinic receptors in Alzheimer's disease. J Neurochem. 1995; 64:1888-91.
-
(1995)
J Neurochem.
, vol.64
, pp. 1888-1891
-
-
Flynn, D.D.1
Ferrari-DiLeo, G.2
Mash, D.C.3
-
87
-
-
0000658715
-
Neurotransmission: The autonomic and somatic motor nervous systems
-
Hardiman JG, Limbird LE, Molinoff PB et al., eds. New York: McGraw-Hill
-
Lefkowitz RJ, Hoffman BB, Taylor P. Neurotransmission: the autonomic and somatic motor nervous systems. In: Goodman and Gilman's the pharmacological basis of therapeutics. 9th ed. Hardiman JG, Limbird LE, Molinoff PB et al., eds. New York: McGraw-Hill; 1996:117-9.
-
(1996)
Goodman and Gilman's the Pharmacological Basis of Therapeutics. 9th Ed.
, pp. 117-119
-
-
Lefkowitz, R.J.1
Hoffman, B.B.2
Taylor, P.3
-
88
-
-
0027399410
-
Relationship between cigarette smoking and Alzheimer's disease in a population-based case-control study
-
Brenner DE, Kukull WA, van Belle G et al. Relationship between cigarette smoking and Alzheimer's disease in a population-based case-control study. Neurology. 1993; 43:293-300.
-
(1993)
Neurology
, vol.43
, pp. 293-300
-
-
Brenner, D.E.1
Kukull, W.A.2
Van Belle, G.3
-
89
-
-
0028080315
-
Risk factors for Alzheimer's disease in Canada
-
The Canadian Study of Health and Aging. Risk factors for Alzheimer's disease in Canada. Neurology. 1994; 44:2073-80.
-
(1994)
Neurology
, vol.44
, pp. 2073-2080
-
-
-
90
-
-
0027337861
-
Smoking and Alzheimer's disease: Protective effect or differential survival bias?
-
Letter
-
Riggs JE. Smoking and Alzheimer's disease: protective effect or differential survival bias? Lancet. 1993; 342:793-4. Letter.
-
(1993)
Lancet
, vol.342
, pp. 793-794
-
-
Riggs, J.E.1
-
91
-
-
0027426440
-
Smoking and neurodegenerative diseases
-
Letter
-
Hardy J, Roberts GW. Smoking and neurodegenerative diseases. Lancet. 1993; 342:1238. Letter.
-
(1993)
Lancet
, vol.342
, pp. 1238
-
-
Hardy, J.1
Roberts, G.W.2
-
92
-
-
0027426440
-
Smoking and neurodegenerative diseases
-
Letter
-
Larrick JW, Wright SC. Smoking and neurodegenerative diseases. Lancet. 1993; 342:1238. Letter.
-
(1993)
Lancet
, vol.342
, pp. 1238
-
-
Larrick, J.W.1
Wright, S.C.2
-
93
-
-
0027953659
-
Smoking associated protection from Alzheimer's and Parkinson's disease
-
Letter
-
Morens DM, Grandinetti A, Reed D et al. Smoking associated protection from Alzheimer's and Parkinson's disease. Lancet. 1994; 343:356-7. Letter.
-
(1994)
Lancet
, vol.343
, pp. 356-357
-
-
Morens, D.M.1
Grandinetti, A.2
Reed, D.3
-
94
-
-
0028986481
-
Apolipoprotein e genotype and association between smoking and early onset Alzheimer's disease
-
Van Duijn CM, Havekes LM, Van Broeckhoven C et al. Apolipoprotein E genotype and association between smoking and early onset Alzheimer's disease. BMJ. 1995; 310:627-31.
-
(1995)
BMJ
, vol.310
, pp. 627-631
-
-
Van Duijn, C.M.1
Havekes, L.M.2
Van Broeckhoven, C.3
-
95
-
-
0002567031
-
New approach to drug therapy in Alzheimer's dementia
-
Maelicke A, Albuquerque EX. New approach to drug therapy in Alzheimer's dementia. Drug Discov Today. 1996; 1:53-9.
-
(1996)
Drug Discov Today
, vol.1
, pp. 53-59
-
-
Maelicke, A.1
Albuquerque, E.X.2
-
96
-
-
0026502543
-
Choline metabolism as a basis for the selective vulnerability of cholinergic neurons
-
Wurtman RJ. Choline metabolism as a basis for the selective vulnerability of cholinergic neurons. Trends Neurosci. 1992; 15:117-22.
-
(1992)
Trends Neurosci.
, vol.15
, pp. 117-122
-
-
Wurtman, R.J.1
-
97
-
-
0023204461
-
+ depolarization on choline kinase and choline acetyltransferase activities in superior cervical sympathetic ganglia excised from rats
-
+ depolarization on choline kinase and choline acetyltransferase activities in superior cervical sympathetic ganglia excised from rats. J Neurochem. 1987; 48:1448-53.
-
(1987)
J Neurochem.
, vol.48
, pp. 1448-1453
-
-
Ando, M.1
Iwata, M.2
Takahama, K.3
-
98
-
-
0024598955
-
Choline increases acetylcholine release and protects against the stimulation-induced decrease in phosphatide levels within membranes of the rat corpus striatum
-
Ulus IH, Wurtman RJ, Mauron C et al. Choline increases acetylcholine release and protects against the stimulation-induced decrease in phosphatide levels within membranes of the rat corpus striatum. Brain Res. 1989; 484:217-27.
-
(1989)
Brain Res.
, vol.484
, pp. 217-227
-
-
Ulus, I.H.1
Wurtman, R.J.2
Mauron, C.3
-
99
-
-
0026510312
-
The nerve growth factor receptor: A multicomponent system that mediates the actions of the neurotrophin family of proteins
-
Barker PA, Murphy RA. The nerve growth factor receptor: a multicomponent system that mediates the actions of the neurotrophin family of proteins. Mol Cell Biochem. 1992; 110:1-15.
-
(1992)
Mol Cell Biochem.
, vol.110
, pp. 1-15
-
-
Barker, P.A.1
Murphy, R.A.2
-
100
-
-
0027966170
-
Disruption of NGF binding to the low affinity neurotrophin receptor p75 LNTR reduces NGF binding to trkA on PC12 cells
-
Barker PA, Shooter EM. Disruption of NGF binding to the low affinity neurotrophin receptor p75 LNTR reduces NGF binding to trkA on PC12 cells. Neuron. 1994; 13:203-15.
-
(1994)
Neuron.
, vol.13
, pp. 203-215
-
-
Barker, P.A.1
Shooter, E.M.2
-
101
-
-
0026766860
-
The nerve growth factor family of receptors
-
Meakin SO, Shooter EM. The nerve growth factor family of receptors. Trends Neurosci. 1992; 15:323-31.
-
(1992)
Trends Neurosci.
, vol.15
, pp. 323-331
-
-
Meakin, S.O.1
Shooter, E.M.2
-
103
-
-
0026334402
-
NGF and bFGF protect rat hippocampal and human cortical neurons against hypoglycemic damage by stabilizing calcium homeostasis
-
Cheng B, Mattson MP. NGF and bFGF protect rat hippocampal and human cortical neurons against hypoglycemic damage by stabilizing calcium homeostasis. Neuron. 1991; 7: 1031-41.
-
(1991)
Neuron.
, vol.7
, pp. 1031-1041
-
-
Cheng, B.1
Mattson, M.P.2
-
104
-
-
0028327218
-
NT-3 and BDNF protect CNS neurons against metabolic/excitotoxic insults
-
Cheng B, Mattson MP. NT-3 and BDNF protect CNS neurons against metabolic/excitotoxic insults. Brain Res. 1994; 640: 56-67.
-
(1994)
Brain Res.
, vol.640
, pp. 56-67
-
-
Cheng, B.1
Mattson, M.P.2
-
105
-
-
0028019154
-
Role of neurotrophins in cholinergic-neurone function in the adult and aged CNS
-
Rylett RJ, Williams LR. Role of neurotrophins in cholinergic-neurone function in the adult and aged CNS. Trends Neurosci. 1994; 17:486-9.
-
(1994)
Trends Neurosci.
, vol.17
, pp. 486-489
-
-
Rylett, R.J.1
Williams, L.R.2
-
107
-
-
0000259231
-
Long term potentiation in the hippocampus: Mechanisms of initiation and modulation by neurotransmitter
-
Collinridge GL. Long term potentiation in the hippocampus: mechanisms of initiation and modulation by neurotransmitter. Trends Pharmacol Sci. 1985; 6:407-11.
-
(1985)
Trends Pharmacol Sci.
, vol.6
, pp. 407-411
-
-
Collinridge, G.L.1
-
108
-
-
0027269660
-
Cortical pyramidal neurone loss may cause glutamatergic hypoactivity and cognitive impairment in Alzheimer's disease: Investigative and therapeutic perspectives
-
Francis PT, Sims NR, Procter AW et al. Cortical pyramidal neurone loss may cause glutamatergic hypoactivity and cognitive impairment in Alzheimer's disease: investigative and therapeutic perspectives. J Neurochem. 1993; 60:1589-604.
-
(1993)
J Neurochem.
, vol.60
, pp. 1589-1604
-
-
Francis, P.T.1
Sims, N.R.2
Procter, A.W.3
-
110
-
-
0027496238
-
A radical hypothesis for neurodegeneration
-
Olanow CW. A radical hypothesis for neurodegeneration. Trends Neurosci. 1993; 16:439-44.
-
(1993)
Trends Neurosci.
, vol.16
, pp. 439-444
-
-
Olanow, C.W.1
-
112
-
-
0028957882
-
Amyloid peptides are toxic via a common oxidative mechanism
-
Schubert D, Behl C, Lesley R et al. Amyloid peptides are toxic via a common oxidative mechanism. Proc Natl Acad Sci U S A. 1995; 92:1989-93.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 1989-1993
-
-
Schubert, D.1
Behl, C.2
Lesley, R.3
-
113
-
-
0029935396
-
The amyloid precursor protein of Alzheimer's disease in the reduction of copper(II) to copper(I)
-
Multhaup G, Schlicksupp A, Hesse L et al. The amyloid precursor protein of Alzheimer's disease in the reduction of copper(II) to copper(I). Science. 1996; 271:1406-9.
-
(1996)
Science
, vol.271
, pp. 1406-1409
-
-
Multhaup, G.1
Schlicksupp, A.2
Hesse, L.3
-
114
-
-
0028270158
-
Brain injury in a dish: A model for reactive gliosis
-
McMillan MK, Thai L, Hong J-S et al. Brain injury in a dish: a model for reactive gliosis. Trends Neurosci. 1994; 17:138-42.
-
(1994)
Trends Neurosci.
, vol.17
, pp. 138-142
-
-
McMillan, M.K.1
Thai, L.2
Hong, J.-S.3
-
115
-
-
0028953529
-
Activation of microglial cells by β-amyloid and interferon-γ
-
Meda L, Cassatella MA, Szendrei GI et al. Activation of microglial cells by β-amyloid and interferon-γ. Nature. 1995; 374:647-50.
-
(1995)
Nature
, vol.374
, pp. 647-650
-
-
Meda, L.1
Cassatella, M.A.2
Szendrei, G.I.3
-
117
-
-
0027235888
-
New Alzheimer's therapy suggested
-
News
-
Schnabel J. New Alzheimer's therapy suggested. Science. 1993; 260:1719-20. News.
-
(1993)
Science
, vol.260
, pp. 1719-1720
-
-
Schnabel, J.1
-
118
-
-
0028085516
-
Estrogen deficiency and risk of Alzheimer's disease in women
-
Paganini-Hill A, Henderson VW. Estrogen deficiency and risk of Alzheimer's disease in women. Am J Epidemiol. 1994; 140:256-61.
-
(1994)
Am J Epidemiol.
, vol.140
, pp. 256-261
-
-
Paganini-Hill, A.1
Henderson, V.W.2
-
119
-
-
0028086440
-
Estrogen replacement therapy in older women
-
Henderson VW, Paganini-Hill A. Estrogen replacement therapy in older women. Arch Neurol. 1994; 51:896-900.
-
(1994)
Arch Neurol.
, vol.51
, pp. 896-900
-
-
Henderson, V.W.1
Paganini-Hill, A.2
-
120
-
-
0028000280
-
The solubilization of model Alzheimer tangles: Reversing the β-pleated sheet conformation induced by aluminum with silicates
-
Fasman GD, Moore CD. The solubilization of model Alzheimer tangles: reversing the β-pleated sheet conformation induced by aluminum with silicates. Proc Natl Acad Sci U S A. 1994; 91:11232-5.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 11232-11235
-
-
Fasman, G.D.1
Moore, C.D.2
-
121
-
-
0027980901
-
Rapid induction of Alzheimer Aβ amyloid formation by zinc
-
Bush AI, Pettingell WH, Multhaup G et al. Rapid induction of Alzheimer Aβ amyloid formation by zinc. Science. 1994; 265:1464-7.
-
(1994)
Science
, vol.265
, pp. 1464-1467
-
-
Bush, A.I.1
Pettingell, W.H.2
Multhaup, G.3
-
122
-
-
0025726462
-
Intramuscular desferrioxamine in patients with Alzheimer's disease
-
Crapper-McLachlan DR, Dalton AJ, Kruck TP et al. Intramuscular desferrioxamine in patients with Alzheimer's disease. Lancet. 1991; 337:1304-8.
-
(1991)
Lancet
, vol.337
, pp. 1304-1308
-
-
Crapper-McLachlan, D.R.1
Dalton, A.J.2
Kruck, T.P.3
|