Molecular genetic analysis of volatile-anesthetic action

Molecular and Cellular Biology

Volumn 16, Issue 7, 1996, Pages 3446-3453

  Keil, Ralph L ^a   Wolfe, Darren ^a   Reiner, Thomas ^a   Peterson, Christopher J ^a,b   Riley, Jody L ^a  

^a PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

^b Dermatology Associates of Lancaster   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENFLURANE; GENE PRODUCT; HALOTHANE; INHALATION ANESTHETIC AGENT; ISOFLURANE; METHOXYFLURANE; PHOSPHOLIPASE A2; SEVOFLURANE;

ARTICLE; DRUG POTENCY; GENE; GROWTH INHIBITION; LIPOPHILICITY; MINIMUM INHIBITORY CONCENTRATION; MINIMUM LUNG ALVEOLUS CONCENTRATION; MOLECULAR CLONING; MOLECULAR GENETICS; MUTANT; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION;

EID: 0029950663     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.7.3446     Document Type: Article

References (39)

1. Altschul, S. F., W. Gish, W. Miller, E. W. Myers, and D. J. Lipman. 1990. Basic local alignment search tool. J. Mol. Biol. 215:403-410.
2. Bendo, A. A., I. S. Kass, J. Hartung, and J. E. Cottrell. 1992. Neurophysiology and neuroanesthesia, p. 871-918. In P. G. Barash, B. F. Cullen, and R. K. Stoelting (ed.), Clinical anesthesia, 2nd ed. Lippincott, Philadelphia.
3. Bhat, P. J., D. Oh, and J. E. Hopper. 1990. Analysis of the GAL3 signal transduction pathway activating GAL4 protein-dependent transcription in Saccharomyces cerevisiae. Genetics 125:281-291.
4. Boeke, J. D., F. LaCroute, and G. R. Fink. 1984. A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance. Mol. Gen. Genet. 197:345-346.
5. Bolivar, F., R. L. Rodriguez, P. J. Greene, M. C. Betlach, H. L. Heyneker, H. W. Boyer, J. H. Crosa, and S. Falkow. 1977. Construction and characterization of new cloning vehicles. II. A multipurpose cloning system. Gene 2:95-113.
6. 2-activating protein. Proc. Natl. Acad. Sci. USA 88:5418-5422.
7. Dastre, A. 1890, Les anesthésiques: physiologie et applications chirurgicales. G. Masson, Paris.
8. Dujon, B., et al. 1994. Complete DNA sequence of yeast chromosome XI. Nature (London) 369:371-377.
9. Gietz, R. D., and A. Sugino. 1988. New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. Gene 74:527-534.
10. Guyer, M. S. 1983. Uses of the transposon γδ in the analysis of cloned genes. Methods Enzymol. 101:362-369.
11. 10a.Jones, S. Personal communication.
12. Koblin, D. D. 1990. Mechanisms of action, p. 51-83. In R. D. Miller (ed.), Anesthesia, 3rd ed. Churchill Livingstone, New York.
13. Krishnan, K. S., and H. A. Nash. 1990. A genetic study of the anesthetic response: mutants of Drosophila melanogaster altered in sensitivity to halothane. Proc. Natl. Acad. Sci. USA 87:8632-8636.
14. Kunz, J., and M. N. Hall. 1993. Cyclosporin A, FK506 and rapamycin: more than just immunosuppression. Trends Biochem. Sci. 18:334-338.
15. Larach, D. R., H. G. Schuler, T. M. Skeehan, and C. J. Peterson. 1990. Direct effects of myocardial depressant drugs on coronary vascular tone: anesthetic vasodilation by lialothane and isoflurane. J. Pharmacol. Exp. Ther. 254:58-64.
16. Lin, Y.-H., and R. L. Keil. 1991. Mutations affecting RNA polymerase I-stimulated exchange and rDNA recombination in yeast. Genetics 127:31-38.
17. Lipnick, R. L. 1986. Charles Ernest Overton: narcosis studies and a contribution to general pharmacology. Trends Pharmacol. Sci. 7:161-164.
18. Lipnick, R. L. 1989. Hans Horst Meyer and the lipoid theory of narcosis. Trends Pharmacol. Sci. 10:265-269.
19. Mead, D. A., E. Szczesna-Skorupa, and B. Kemper. 1986. Single-stranded DNA 'blue' T7 promoter plasmids: a versatile tandem promoter system for cloning and protein engineering. Protein Eng. 1:67-74.
20. Morgan, P. G., M. M. Sedensky, P. M. Meneely, and H. F. Cascorbi. 1988. The effect of two genes on anesthetic response in the nematode Caenorhabditis elegans. Anesthesiology 69:246-251.
21. Neer, E. J., C. J. Schmidt, R. Nambudripad, and T. F. Smith. 1994. The ancient regulatory-protein family of WD-repeat proteins. Nature (London) 371:297-300.
22. Overton, C. E. 1901. Studies of narcosis. Gustav Fischer, Jena, Germany. [English translation, 1991. R. F. Lipnick (ed.). Chapman and Hall, London.]
23. 2 activating protein and the G protein β-subunits: a new concept of effector protein activation in signal transduction? Trends Biochem. Sci. 18:292-293.
24. Pringle, J. R., R. A. Preston, A. E. M. Adams, T. Stearns, D. G. Drubin, B. K. Haarer, and E. W. Jones. 1989. Fluorescence microscopy methods for yeast. Methods Cell Biol. 31:357-435.
25. Riles, L., J. E. Dutchik, A. Baktha, B. K. McCauley, E. C. Thayer, M. P. Leckie, V. V. Braden, J. E. Depke, and M. V. Olson. 1993. Physical maps of the six smallest chromosomes of Saccharomyces cerevisiae at a resolution of 2.6 kilobase pairs. Genetics 134:81-150.
26. Rose, M. D., P. Novick, J. H. Thomas, D. Botstein, and G. R. Fink. 1987. A Saccharomyces cerevisiae genomic plasmid hank based on a centromere-containing shuttle vector. Gene 60:237-243.
27. Rose, M. D., F. Winston, and P. Hieter. 1990. Methods in yeast genetics: a laboratory course manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
28. Rusy, B. F., and H. Komai. 1987. Anesthetic depression of myocardial contractility: a review of possible mechanisms. Anesthesiology 67:745-766.
29. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
30. Sedensky, M. M., H. F. Cascorbi, J. Meinwald, P. Radford, and P. G. Morgan. 1994. Genetic differences affecting the potency of stereoisomers of halothane. Proc. Natl. Acad. Sci. USA 91:10054-10058.
31. Sedensky, M. M., and P. M. Meneely. 1987. Genetic analysis of halothane sensitivity in Caenorhabditis elegans. Science 236:952-954.
32. Stevens, W. C., and H. G. G. Kingston. 1992. Inhalation anesthesia, p. 439-465. In P. G. Barash, B. F. Cullen, and R. K. Stoelting (ed.), Clinical anesthesia, 2nd ed. Lippincott, Philadelphia.
33. Stoelting, R. K., and S. F. Dierdorf. 1993. Ischemic heart disease, p. 1-20. In R. K. Stoelting and S. F. Dierdorf (ed.), Anesthesia and co-existing disease, 3rd ed. Churchill Livingstone, New York.
34. 32a.Tevethia, M. J., and S. S. Tevethia. Unpublished data.
35. Thompson, D. L., D. Kalderon, A. E. Smith, and M. J. Tevethia. 1990. Dissociation of Rb-binding and anchorage-independent growth from immortalization and tumorigenicity using SV40 mutants producing N-terminally truncated large T antigens. Virology 178:15-34.
36. 2-activating protein. Yeast 10:663-679.
37. van der Voorn, L., and H. L. Ploegh. 1992. The WD-40 repeat. FEBS Lett. 307:131-134.
38. 2-activating protein. Gene 161:237-241.
39. Zehfus, B. R., A. D. McWilliams, Y.-H. Lin, M. F. Hoekstra, and R. L. Keil. 1990. Genetic control of RNA polymerase I-stimulated recombination in yeast. Genetics 126:41-52.