Synthesis and antibacterial activities of novel C(7)-catechol-substituted cephalosporins (II)

Journal of Antibiotics

Volumn 49, Issue 5, 1996, Pages 499-501

  Kim, Yong Zu ^a   Lim, Jong Chan ^a   Yeo, Jae Hong ^a   Bang, Chan Sik ^a   Kim, Sam Sik ^a   Lee, Tae Hee ^a   Oh, Seong Ho ^a   Moon, Young Choon ^a   Lee, Chang Seok ^a  

^a LG Chemical Ltd   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CATECHOL DERIVATIVE; CEFTAZIDIME; CEPHALOSPORIN DERIVATIVE;

ANIMAL EXPERIMENT; ANTIBACTERIAL ACTIVITY; AREA UNDER THE CURVE; ARTICLE; DRUG HALF LIFE; DRUG SYNTHESIS; INTRAVENOUS DRUG ADMINISTRATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0029949956     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.49.499     Document Type: Article

References (11)

1. KIM, Y.-Z.; J.-C. LIM, J.-H. YEO, C.-S. BANG, S.-S. KIM, T. H. LEE, S. H. OH, Y.-C. MOON & C.-S. LEE: Synthesis and biological activities of novel C(7)-catechol-substituted cephalosporins (I). J. Antibiotics 49: 496-498, 1996
2. KAMIYA, T.; T. NAITO, Y. KAI, Y, KOMATSU, M. SASHO, N. SATO, T. NAKAMURA, S. NEGI, Y. MACHIDA & H. YAMAUCHI: Synthesis and structure-activity relationships of fluoromethoxy-imino containing cephems; E1077, a novel parenteral cephem. Program and Abstracts of the 30th Intersci. Conf. on Antimicrob. Agents Chemother., No. 447, p. 160, Atlanta, Oct. 21∼24, 1990
3. OKITA, T.; K. IMAE, T. HASEGAWA, S. IIMURA, S. MASUYOSHI, H. KAMACHI & H. KAMEI: Synthesis and antibacterial activity of cephalosporins having a catechol in the C3 side chain. J. Antibiotics 46: 833-839, 1993
4. MURAKAMI, K.; M. OHASHI, A. MATSUNAGA, I. YAMAMOTO, A. TOMIGUCHI & H. NOHIRA: Optical resolution by preferential crystallization of 2-(3,4-carbonyl dioxyphenyl)-2-(phthalimidooxy)acetic acid. Bull. Chem. Soc. Jpn. 65: 3288-3293, 1992
5. WATANABE, N. A.; T. NAGASU, K. KATSU & K. KITOH: E-0702, a new cephalosporin, is incorporated into E. coli cells via the tonB dependent iron transport mechanism. Antimicrob. Agents Chemother. 31, 497-504, 1987
6. JONES, R. N. & M. E. ERWIN: In vitro evaluation of Ro 09-1227, a novel catechol-substituted cephalosporin. Antimicrob. Agents Chemother. 36: 233-238, 1992
7. MOCHIZUKI, H.; H. YAMADA, Y. OIKAWA, K. MURAKAMI, J. ISHIGURO, H. KOSUZUME, N. ARIZAWA & E. MOCHIDA: Bactericidal activity of M14659 enhanced in low-iron environments. Antimicrob. Agents Chemother. 32: 1648-1654, 1988
8. NAKAGAWA, S.; M. SANADA, K. MATSUDA, T. HASHIZUME, Y. ASAHI, R. USHIJIMA, N. OHTAKE & N. TANAKA: In vitro and in vivo antibacterial activities of BO-1341, a new antipseudomonal cephalosporin. Antimicrob. Agents Chemother. 33: 1423-1427, 1989
9. ARNOULD, J. C.; A. BERTRANDIE, T. G. C. BIRD, D. BOUCHEROT, F. JUNG, J. J. LOHMANN, A. OLIVER, J. P. BAILEY, W. BELL & G. M. DAVIES: Synthesis and structure-activity relationship of cephalosporins with C-3′ catechol-containing residues. J. Med. Chem. 35: 2631-2642, 1992
10. SILLEY, P.; J. W. GRIFFITHS, D. MONSEY & A. M. HARRIS: Mode of action of GR69153, a novel catechol-substituted cephalosporin, and its interaction with the tonB dependent iron transport system. Antimicrob. Agents Chemother. 34: 1806-1808, 1990
11. NEILANDS, J. B.: Microbial envelope proteins related to iron. Annu. Rev. Microbiol. 36: 285-309, 1982