Differences in the anti-basement membrane zone antibodies in ocular and pseudo-ocular cicatricial pemphigoid

Current Eye Research

Volumn 15, Issue 5, 1996, Pages 521-532

  Bhol, Kailash ^a   Mohimen, Aloke ^a   Neumann, Ron ^b   Yunis, Juan ^b   Foster, Stephen ^b   Yunis, Edmond J ^b   Ahmed, A Razzaque ^a,c  

^a HARVARD SCHOOL OF DENTAL MEDICINE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c CENTER FOR BLOOD RESEARCH   (United States)

Author keywords

Anti basement membrane zone antibody; Autoantigen; Cicatricial pemphigoid; Human; Immunoblot technique; MHC class II genes; Pseudo or drug related ocular cicatricial pemphigoid

Indexed keywords

ANTIBODY; ANTIGLAUCOMA AGENT; AUTOANTIGEN; AZATHIOPRINE; CARBACHOL; COMPLEMENT; DAPSONE; DIPIVEFRINE; EYE DROPS; IMMUNOGLOBULIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TIMOLOL MALEATE;

ADULT; AGED; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; BASEMENT MEMBRANE; CELL LYSATE; CLINICAL ARTICLE; CONJUNCTIVA; CONTROLLED STUDY; DERMIS; DOT HYBRIDIZATION; EPIDERMIS; EPIDERMOLYSIS BULLOSA ACQUISITA; ESOPHAGUS; ETIOLOGY; FEMALE; GENE FREQUENCY; GLAUCOMA; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; MONKEY; MUCOUS MEMBRANE PEMPHIGOID; PEMPHIGUS VULGARIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PSEUDO OCULAR CICATRICIAL PEMPHIGOID; SCAR FORMATION; SKIN; SQUAMOUS EPITHELIUM; STAINING;

EID: 0029949361     PISSN: 02713683     EISSN: None     Source Type: Journal    
DOI: 10.3109/02713689609000763     Document Type: Article

References (29)

1. Hirst, J., Werblin, T. and Novae, M. (1982) Drug-induced cicatrizing conjunctivitis simulating pemphigoid . Cornea, 1, 121-128.
2. Fiore, P. N., Jacobs, I. H. and Goldberg, D. B. (1987) Drug-induced pemphigoid. Arch. Oplithalm. 105, 1660-1663.
3. Gallagher, J. R. (1959) Ocular pemphigoid. Am. J. Ophthalmol. 48, 355-359.
4. Furey, N., West, C., Andrews, T. and Paul, P. D. (1975) Immunofluorescent studies of ocular cicatricial pemphigoid. Am. J. Ophthalmol. 80, 825-828.
5. Herron, B. E. (1975) Immunologic aspects of cicatricial pemphigoid. Am. J. Ophthalmol. 79, 271-274.
6. Mondino, B. J., Ross, A. N., Rabin, B. S. and Brown, S. I. (1977) Autoimmune phenomena in ocular cicatricial pemphigoid. Am. J. Ophthalmol. 83, 443-446.
7. Waltham, S. R. and Yarian, D. (1974) Circulating antibodies in ocular pemphigoid. Am. J. Ophthalmol. 77, 891-893.
8. Tagami, H. and Imamura, S. (1974) Benign mucous membrane pemphigoid demonstration of circulating and tissue bound membrane antibodies. Arch. Dermatol. 109, 711-713.
9. Patten, J. T., Cavanagh, H. D. and Allansmith, M. R. (1976) Induced ocular pseudo-pemphigoid. Am. J. Ophthalmol. 82, 272-276.
10. Lass, J. H., Thoft, R. A. and Dohlman, C. H. (1983) Idoxuridine-induced conjunctival cicatrization. Arch. Ophthalmol. 101, 747-750.
11. Norn, M. S. (1977) Pemphigoid related to epinephrine treatment. Am. J. Ophthalmol. 83, 138-143.
12. Rahi, A. H. S., Chapman, C. M., Garner, A. and Wright, P. (1976) Pathology of practolol-induced ocular toxicity. Br. J. Ophthalmol. 60, 312-323.
13. Pouliquen, Y., Patey, A., and Foster, C. S. (1986) Drug-induced cicatricial pemphigoid affecting the conjunctiva. Ophthalmol. 93, 775-783.
14. Mondino, B. J. and Brown, S. L. (1981) Ocular cicatricial pemphigoid. Ophthalmol. 88, 95-100.
15. Mondino, B. J., Brown, S. L. and Rabin, B. S. (1978) Autoimmune phenomena of the external eye. Ophthalmol. 85, 801-817.
16. Mondino, B. J. and Brown, S. I. (1983) Immunosuppressive therapy in ocular cicatricial pemphigoid. Am. J. Ophthalmol. 96, 453-459.
17. Bernard, P., Prost, C., Lecerf, L., Intrator, P., Comemale, C., Bedane, J. C., Roujeau, J., Revuj, J., Bonnetblance, M., and Dubrertret, L. (1990) Studies of cicatricial pemphigoid autoantibodies using direct immunoelectron microscopy and immunoblot analysis. J. Invest. Dermatol. 94, 630-635.
18. Bernard, P., Prost, C., Aucourtrurier, P., Dupepraire, N., Denis, F. and Bonnetblance, J. M. (1991) The subclass distribution of IgG autoantibodies in cicatricial pemphigoid and epidermolysis bullosa acquisita. J. Invest. Dermatol. 97, 259-263.
19. Chan, L. S., Hammerberg, C. and Cooper, K. D. (1990) Cicatricial pemphigoid. Arch. Dermatol. 126, 1466-1468.
20. Ahmed, A. R., Foster, C. S., Zaltas, M., Notani, G., Awdeh, Z., Alper, C. A., Yunis, E. J. (1991) Association of DQw7 (DQB1*0301) with ocular cicatricial pemphigoid. Proc. Natl. Acad. Sci. USA, 88, 11579-11582.
21. Ahmed, A. R. and Workman, S. (1983) Pemphigus-like antibodies. Arch. Dermatol. 119, 17-21.
22. Labib, R. S., Anhalt, G. J., Patel, H. P., Mutasim, D. F., and Diaz, L. (1986) Molecular heterogenicity of the bullous pemphigoid antigens as detected by immunoblotting. J. Immunol. 136, 1231-1235.
23. Woodley, D., Sander, D. and Tolley, M. J. (1983) Localization of basement membrane components after dermalepidermal junction separation. J. Invest. Dermatol. 81, 149-153.
24. Woodley, E., Briggaman, R. A. and O'Keefe, E. J. (1984) Identification of the skin basement-membrane autoantigen in epidermolysis bullosa acquisita. N. Eng. J. Med. 310, 1007-1013.
25. Porath, J. and Axen, R. (1976) Immobilization of enzymes to agar, agarose and Sephadex supports. In Methods in Enzymology. P. 19-45. Academic Press, New York USA.
26. Laemmli, U. K. (1970) Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature, 277, 680-685.
27. Towbin, H., Staehlin, T. and Gordon, J. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets. Procedures and some applications. Proc. Natl. Acad. Sci. USA, 76, 4350-4354.
28. Kelly, S. E. and Wajnarowska, F. (1988) The use of chemically split tissue in detection of circulating anti-basement membrane zone antibodies in bullous pemphigoid and cicatricial pemphigoid. Brit. J. Dermatol. 118, 31-40.
29. Sarret, Y., Hall, R., Cobo, L. M. and Thivolet, J. (1991) Salt-split human skin substrate for the immunofluorescence screening of serum from patients with cicatricial pemphigoid and a new method of immunoprecipitation with IgA antibodies. J. Am. Acad. Dermatol. 24, 952-958.