Acamprosate and alcohol: II. Effects on alcohol withdrawal in the rat

European Journal of Pharmacology

Volumn 305, Issue 1-3, 1996, Pages 45-50

  Spanagel, Rainer ^a   Putzke, Jörg ^a   Stefferl, Andreas ^a   Schöbitz, Bernd ^a   Zieglgänsberger, Walter ^a  

^a MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

Author keywords

acamprosate; alcohol; radiotelemetry; rat; withdrawal

Indexed keywords

ACAMPROSATE; ALCOHOL;

ALCOHOL BLOOD LEVEL; ALCOHOL CONSUMPTION; ALCOHOL WITHDRAWAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY TEMPERATURE; CONTROLLED STUDY; FLUID INTAKE; FOOD INTAKE; HYPERACTIVITY; HYPERTHERMIA; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MOTOR ACTIVITY; NONHUMAN; PRIORITY JOURNAL; RAT; TELEMETRY;

EID: 0029948813     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(96)00175-6     Document Type: Article

References (19)

1. Feuerlein, W., 1980, Alcohol withdrawal syndrom, in: Psychopharmacology of Alcohol, ed. M. Sandler (Raven Press, New York) p. 215.
2. Gallaher, E.J. and D.A. Egner, 1987, Rebound hyperthermia follows ethanol-induced hypothermia in rats, Psychopharmacology 91, 34.
3. Gallaher, E.J., D.A. Egner and J.R. Sven, 1985, Automated remote temperature measurement in small animals using a telemetry/microcomputer interface, Comp. Biol. Med. 15, 103.
4. Gewiss, M., C. Heidebreder, L. Opsomer, Ph. Durbin and Ph. DEWitte, 1991, Acamprosate and diazepam differentially modulate alcohol-induced behavioural and cortical alterations in rats following chronic inhalation of ethanol vapour, Alcohol Alcoholism 26, 129.
5. Heyne, A., G. Slodkowska and J. Wolffgramm, 1991, Physical dependence on ethanol vs. rebound phenomena in an animal model of alcoholism, Naunyn-Schmied. Arch. Pharmacol. 344, R70.
6. Hunter, B.E., J.N. Riley and D.W. Walker, 1972, Ethanol dependence in the rat: a parametric analysis, Pharmacol. Biochem. Behav. 3, 619.
7. Ladewig, D., T. Knecht, P. Leher and A. Fendl, 1993, Acamprosat - ein Stabilisierungsfaktor in der Langzeitentwöhnung von Alkoholabhängigen, Ther. Umschau 50, 182.
8. Le Magnen, J., G. Tran and J. Durlach, 1987, Lack of effects of Ca-acetyl-homotaurinate on chronic and acute toxicities of ethanol in rats, Alcohol 4, 103.
9. Lhuintre, J.-P., N.D. Moore, C. Saligaut, F. Boismare, M. Daoust, P. Chretien, G. Tran and B. Hillemand, 1985, Ability of calcium bis acetyl homotaurine, a GABA agonist, to prevent relapse in weaned alcoholics, Lancet i, 1014.
10. Lhuintre, J.-P., N.D. Moore, G. Tran, L. Steru, S. Langrenon, M. Daoust, Ph. Parot, Ph. Ladure, C. Libert, F. Boismare and B. Hillemand, 1990, Acamprosate appears to decrease alcohol intake in weaned alcoholics, Alcohol Alcoholism 25, 613.
11. Liljequist, S., S. Ahlenius and J. Engel, 1977, The effect of chronic ethanol treatment on behaviour and central monoamines in the rat, Naunyn-Schmied. Arch. Pharmacol. 300, 205.
12. Majchrowicz, E., 1975, Induction of physical dependence upon ethanol and the associated behavioral changes in rats, Psychopharmacologia 43, 245.
13. Mello, N.K., 1973, A review of methods to induce alcohol addiction in animals, Pharmacol. Biochem. Behav. 1, 89.
14. Moore, N.D. and C. Libert, 1991, Acamprosate, citalopram, and alcoholism, Lancet 337, 1228.
15. Pohorecky, L.A. and P. Roberts, 1991, Development of tolerance to and physical dependence on ethanol: daily versus repeated cycles treatment with ethanol, Alcohol Clin. Exp. Res. 15, 824.
16. Putzke, J., R. Spanagel, T.R. Tölle and W. Zieglgänsberger, 1995, Acamprosate differentially alters PTZ- and PTZ plus ethanol withdrawal-induced c-fos expression in the rat brain, Alcohol Alcoholism 30, 550.
17. Sass, H., M. Soyka, K. Mann and W. Zieglgänsberger, 1996, Relapse prevention by acamprosate: results from a placebo controlled study in alcohol dependence, Arch. Gen. Psychiatry (in press).
18. Spanagel, R., S.M. Hölter, K. Allingham and W. Zieglgänsberger, 1995, Acamprosate and reinstatement behaviour in the alcohol-dependent rat, Alcohol Alcoholism 30, 551.
19. Waller, M.B., W.J. McBride, L. Lumeng and T.K. Li, 1982, Induction of dependence on ethanol by free-choice drinking in alkohol-preferring rats, Pharmacol. Biochem. Behav. 16, 501.