Host genetics and infectious disease

Parasitology

Volumn 112, Issue SUPPL., 1996, Pages

  Weatherall, D J ^a  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

Haemoglobinopathy; Host genetics; Malaria; Red cell polymorphism; Thalassaemia

Indexed keywords

CONFERENCE PAPER; ERYTHROCYTE; GENETIC POLYMORPHISM; GENETICS; HEMOGLOBINOPATHY; HOST PARASITE INTERACTION; HUMAN; MALARIA; NONHUMAN; PRIORITY JOURNAL; THALASSEMIA;

ANIMALS; ERYTHROCYTES; GENETIC PREDISPOSITION TO DISEASE; HEMOGLOBINOPATHIES; HUMANS; MALARIA; POLYMORPHISM, GENETIC; SELECTION (GENETICS);

EID: 0029948593     PISSN: 00311820     EISSN: None     Source Type: Journal    
DOI: 10.1017/s0031182000076630     Document Type: Article

References (30)

1. BENNETT, S. T., LUCASSEN, A. M., GOUGH, S. C. L., POWELL, E. E., UNDLIEN, D. E., PRITCHARD, L. E., MERRIMAN, M. E., KAWAGUCHI, Y., DRONSFIELD, M., PICIOT, F., NERUP, J., BOUZEKRI, N., CAMBON-THOMSEN, A., RONNINGEN, K. S., BARNETT, A. H., BAIN, S. C. & TODD, J. A. (1995). Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus. Nature Genetics 9, 284-92.
2. DAVIES, J. L., KAWAGUCHI, Y., BENNETT, S. T., COPEMAN, J. D., CORDELL, H. J., PRITCHARD, L. E., REED, P. W., GOUGH, S. C. L., JENKINS, S. C., PALMER, S. M., BALFOUR, K. W., ROWE, B., FARRALL, M., BARNETT, A. H., BAIN, S. C. & TODD, A. J. (1994). A genome-wide search for human type 1 diabetes susceptibility gene. Nature 371, 130-6.
3. FLINT, J., HARDING, R. M., BOYCE, A. J. & CLEGG, J. B. (1993). The population genetics of the haemoglobinopathies. Clinics in Haematology 6, 215-62.
4. FRIEDMAN, M. J., ROTH, E. F., NAGEL, R. L. & TRAEGER, W. (1979). Plasmodium falciparum; physiological interactions with the human sickle cell. Experimental Parasitology 47, 73-80.
5. GARROD, A. E. (1931). The Inborn Factors in Disease. An Essay. Oxford: Oxford University Press.
6. HALDANE, J. B. S. (1948). The rate of mutation of human genes. Proceedings of the Eighth International Congress of Genetics and Heredity. Hereditas 35, (Suppl.) 267-73.
7. HILL, A. V. S., ALLSOPP, C. E. M., KWIATKOWSKI, D., ANSTEY, N. M., TWUMASI, P., ROWE, P. A., BENNETT, S., BREWSTER, D., MCMICHAEL, A. J. & GREENWOOD, B. M. (1991). Common west African HLA antigens are associated with protection from severe malaria. Nature 352, 595-600.
8. HILL, A. V. S., ELVIN, J., WILLIS, A., AIDOO, M., ALLSOPP, C. E. M., GOTCH, F. M., GAO, X. M., TAKIGUCHI, M., GREENWOOD, B. M., TOWNSEND, A. R. M., MCMICHAEL, A. J. & WHITTLE, H. C. (1992). Molecular analysis of the association of HLA-B53 and resistance to severe malaria. Nature 360, 434-9.
9. JAROLIM, P., PALEK, J., AMATO, D., HASSAN, K., SAPAK, P., NURSE, G. T., RUBIN, H. L., ZHAI, S., SAHR, K. E. & LIU, S. C. (1991). Deletion in erythrocyte band 3 gene in malaria-resistant Southeast Asian ovalocytosis. Proceedings of the National Academy of Sciences USA 88, 11022-6.
10. KWIATKOWSKI, D., HILL, A. V. S., SAMBOU, I., TWUMASI, P., CASTRACANE, J., MANOGUE, K. R., CERAMI, A., BREWSTER, D. R. & GREENWOOD, B. M. (1990). TNF concentration in fatal cerebral, non-fatal cerebral, and uncomplicated Plasmodium falciparum malaria. Lancet 336, 1201-4.
11. KWIATKOWSKI, D. (1995). Malarial toxins and the regulation of parasite density. Parasitology Today 11, 206-12.
12. LUZZATTO, L., NWACHUKU, P. S. & REDDY, S. (1970). Increased sickling of parasitised erythrocytes is the mechanisms of resistance against malaria in the sickle cell trait. Lancet i, 319-21.
13. LUZZI, G. A., MERRY, A. H., NEWBOLD, C. I., MARSH, K., PASVOL, G. & WEATHERALL, D. J. (1991). Surface antigen expression on Plasmodium falciparum-infected erythrocytes is modified in αand β thalassaemia. Journal of Experimental Medicine 173, 785.
14. MCGUIRE, W., HILL, A. V. S., ALLSOPP. C. E. M., GREENWOOD, B. M. & KWIATKOWSKI, D. (1994). Variation in the TNH-α promoter region associated with susceptibility to cerebral malaria. Nature 371, 508-11.
15. MILLER, L. H. (1994). Impact of malaria on genetic polymorphism and genetic diseases in Africans and African Americans. Proceedings of the National Academy of Sciences USA 91, 2415-19.
16. MOURANT, A. E., KOPEC, A. C. & DOMANIEWSKA-SOBEZAK, K. (1978). Blood Groups and Disease. Oxford: Oxford University Press.
17. MURPHY, P. M. (1993). Molecular mimicry and the generation of host defense protein diversity. Cell 72, 823-6.
18. NEEL, J. V. (1962). A 'thrifty' genotype rendered detrimental by progress? American Journal of Human Genetics 14, 353-61.
19. O'BRIEN, S. J. (1991). Ghetto legacy. Molecular Evolution 1, 209-11.
20. PASVOL, G. & WEATHERALL, D. J. (1978). A mechanism for the protective effect of haemoglobin S against P. falciparum malaria. Nature 274, 701-3.
21. PASVOL, G. & WILSON, R. J. M. (1982). The interaction of malarial parasites with red blood cells. British Medical Bulletin 38, 133-10.
22. RUWENDE, C., KHOO, S. C., SNOW, R. W., YATES, S. N. R., KWIATKOWSKI, D., GUPTA, S., WARN, P., ALLSOPP, C. E. M., GILBERT, S. C., PESCHU, N., NEWBOLD, C. I., GREENWOOD, B. M., MARSH, K. & HILL, A. V. S. (1995). Natural selection of hemi- and heterozygotes for G6PD deficiency in Africa by resistance to severe malaria. Nature 376, 246-9.
23. THURSZ, M., KWIATKOWSKI, D., ALLSOPP, C. E. M., GREENWOOD, B. M., THOMAS, H. C. & HILL, A. V. S. (1995). Association between an MHC class II allele and clearance of hepatitis virus in the Gambia. New England Journal of Medicine 332, 1065-9.
24. VAXILLAIRE, M., BOCCIO, V., PHILIPPI, A., VIGOUROUX, C., TERWILLIGER, J., PASSA, P., BECKMAN, J. S., VELHO, G., LATHROP, G. M. & FROUGEL, P. (1995). A gene for early-onset non-insulin dependent diabetes mellitus (Maturity Onset Diabetes of the Young) maps to chromosome 12q. Nature Genetics 9, 418-23.
25. WEATHERALL, D. J., BELL, J. I., CLEGG, J. B., FLINT, J., HIGGS, D. R., HILL, A. V. S., PASVOL, G. & THEIN, S. L. (1988). Genetic factors as determinants of infectious disease transmission in human communities. Philosophical Transactions of the Royal Society of London B 321, 327-48.
26. WEATHERALL, D. J. & CLEGG, J. B. (1981). The Thalassaemia Syndromes (3rd ed.). Oxford: Blackwell Scientific Publications.
27. WEISS, K. M., FERRELL, R. E. & HARRIS, C. L. (1984). A New World syndrome of metabolic diseases with a genetic and evolutionary basis. Yearbook of Physical Anthropology 27, 153-78.
28. + thalassaemia to severe malaria: implications for the time depth of malarial selection. Proceedings of the British Society of Parasitology 5th Malaria Meeting. 13-14.
29. ZHANG, Y., PROENCA, R., MAFFEI, M., BARONE, M., LEOPOLD, L. & FRIEDMAN, J. M. (1994). Positional cloning of the mouse obese gene and its human homologue. Nature 372, 425-32.
30. ZIMMET, P., DOWSE, G., FINCH, C., SERJEANTSON, S. & KING, H. (1990). The epidemiology and natural history of NIDDM; lessons from the South Pacific. Diabetes and Metabolic Reviews 6, 91-124.