Does total parenteral nutrition-induced intestinal mucosal atrophy occur in humans and can it be affected by enteral supplements?

Current Opinion in Gastroenterology

Volumn 12, Issue 2, 1996, Pages 169-173

  Alpers, David H ^a   Stenson, William F ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMINE; SALICYLATE SODIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ATROPHY; DIET SUPPLEMENTATION; ENTERIC FEEDING; HUMAN; INTESTINE FUNCTION; INTESTINE MUCOSA; MALNUTRITION; NONHUMAN; NUTRITIONAL SUPPORT; PARENTERAL NUTRITION; SHORT SURVEY; STARVATION;

EID: 0029948195     PISSN: 02671379     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001574-199603000-00011     Document Type: Short Survey

References (59)

1. Dowling RH: Cellular and molecular basis of intestinal and pancreatic adaptation. Scand J Gastroenterol Suppl 1992, 193:64-67.
2. Alpers DH: Protein synthesis in intestinal mucosa: the effect of route of administration of precursor amino acids. J Clin Invest 1972, 51:2621-2630.
3. Sitren HS, Bryant M, Ellis LM: Species differences in TPN-induced intestinal villus atrophy. JPEN J Parenter Enteral Nutr 1992, 16(suppl):30S.
4. Bark T, Svenberg T, Theodorsson E, Uribe A, Wennberg A: Glutamine supplementation does not prevent small bowel mucosal atrophy after total parenteral nutrition in the rat. Clin Nutr 1994, 13:79-84.
5. Chu KU, Evers BM, Ishizuka J, Townsend CM Jr, Thompson JC: Role of bombesin on gut mucosal growth. Ann Surg 1995, 222:94-100.
6. Goodlad RA, Plumb JA, Wright NA: Epithelial cell proliferation and intestinal absorptive function during starvation and refeeding in the rat. Clin Sci (Colch) 1988:74301-74306.
7. Buts J-P, Vijverman V, Barudi C, de Keyser N, Maldague P, Dive C: Refeeding after starvation in the rat: comparative effect of lipids, proteins and carbohydrates on jejunal and ileal mucosal adaptation. Eur J Clin Invest 1990, 20:441-452.
8. Heird WC, Tsang HL, MacMillan R, Kaplan R, Rosensweig M: Comparative effects of total parenteral nutrition, oral feedings, and starvation on rat small intestine. Pediatr Res 1974, 8:107.
9. Gupta PD, Waheed AA: Effect of starvation on glucose transport and membrane fluidity in rat intestinal epithelial cells. FEBS Lett 1992, 300:263-267.
10. Maxton DG, Cynk EU, Jenkins AP, Thompson RPH: Effect of dietary fat on the small intestinal mucosa. Gut 1989, 30:1252-1255.
11. Koruda MJ, Rolandelli RH, Bliss DZ, Hastings J, Rombeau JL, Settle RG: Parenteral nutrition supplementation with short chain fatty acids: effect on the small bowel mucosa in normal rats. Am J Clin Nutr 1990, 51:658-669.
12. Payne-James JJ, Grimble GK: The present status of glutamine. Curr Opin Gastroenterol 1995, 11:161-167.
13. O'Dwyer ST, Smith RJ, Hwang TL, Wilmore DW: Maintenance of small bowel mucosa with glutamine enriched parenteral nutrition. JPEN J Parenter Enteral Nutr 1989, 13:579-585.
14. Okuma T, Kaneko H, Chen K, Ogawa N, Torigoe Y, Miyauchi Y, Tosaka M: Total parenteral nutrition supplemented with L-alanyl-L-glutamine and gut structure and protein metabolism in septic rats. Nutrition 1994, 10:241-245.
15. Spaeth G, Gottwald T, Specian RD, Mainous MR, Berg RD, Deitch EA: Secretory immunoglobulin A, intestinal mucin, and mucosal permeability in nutritionally induced bacterial translocation in rats. Ann Surg 1994, 220:798-808.
16. Brunser O, Reid A, Monckeberg F, Maccioni A, Contreras I: Jejunal mucosa in infant malnutrition. Am J Clin Nutr 1968, 21:976-981.
17. Martins Campos JV, Neto UF, Patricio FRS, Wehva J, Carvallo AA, Shiner M: Jejunal mucosa in marasmic children: clinical, pathological and fine structural evaluation on the effect of protein-energy undernutrition and environmental contamination. Am J Clin Nutr 1979, 32:1575-1591.
18. Winick M, ed: Hunger Diseases: Studies by the Jewish Physicians in the Warsaw Ghetto, vol 7. New York: John Wiley & Son; 1979.
19. Guedon C, Schmitz J, Lerebours E, Metayer J, Audran E, Hernat J, Colin R: Decreased brush border hydrolase activities without gross morphologic changes in human intestinal mucosa after prolonged total parenteral nutrition of adults. Gastroenterology 1986, 90:373-378.
20. Adibi SA, Allen ER: Impaired jejunal absorption rates of essential amino acids induced by either dietary, caloric or protein deprivation in man. Gastroenterology 1970, 59:404-413.
21. Rossi TM, Lee PC, Young C, Tjota A: Small intestinal mucosa changes, including epithelial cell proliferative activity, of children receiving total parenteral nutrition (TPN). Dig Dis Sci 1993, 38:1608-1613.
22. Pironi L, Paganelli GM, Miglioli M, Biasco G, Santucci R, Ruggeri E, Difebo G, Barbara L: Morphologic and cytoproliferative patterns of duodenal mucosa in two patients after long-term total parenteral nutrition: changes with oral refeeding and relation to intestinal resection. JPEN J Parenter Enteral Nutr 1994, 18:351-354.
23. Buchman AL, Moukarzei AA, Bhuta S, Belle M, Ament ME, Eckhert CD, Hollander D, Gombein J, Kopple JD, Vijayaroghavan SR: Parenteral nutrition is associated with intestinal morphologic and functional changes in humans. J Parenter Enteral Nutr 1995, 19:453-460.
24. Stehle P, Zander J, Mertes N, Puchstein CH, Lewin P, Furst P: Effect of parenteral glutamine peptide supplements on muscle glutamine loss and nitrogen balance after major surgery. Lancet 1989, 1:231-233.
25. Hammarqvist F, Wemerman J, Ali R, von der Dechan A, Vinmars E: Addition of glutamine to total parenteral nutrition after elective abdominal surgery spares free glutamine in muscle, counteracts the fall in muscle protein synthesis, and improves nitrogen balance. Ann Surg 1989, 209:455-461.
26. MacBurney M, Young LS, Ziegler TR, Wilmore DW: A cost-evaluation of glutamine-supplemented parenteral nutrition in adult bone marrow transplant patients. J Am Diet Assoc 1994, 94:1263-1266.
27. O'Riordain MG, Fearon KCH, Ross JA, Rogers P, Falconer JS, Bartolo DC, Gorden OJ, Carter DC: Glutamine-supplemented total parenteral nutrition enhances T-lymphocyte response in surgical patients undergoing colorectal resection. Ann Surg 1994, 220:212-221.
28. van Zaanen HCT, van der Lelie H, Timmer JG, Furst P, Sauerewein HP: Parenteral glutamine dipeptide supplementation does not ameliorate chemotherapy-induced toxicity. Cancer 1994, 74:2879-2884.
29. Hornsby-Lewis L, Shike M, Brown P, Klarg M, Pearlstone D, Breman MF: L-glutamine supplementation in home total parenteral nutrition patients: stability, safety, and effects on intestinal absorption. JPEN J Parenter Enteral Nutr 1994, 18:268-273.
30. van der Hulst RRWJ, van Kreel BK, von Meyenfeldt MF, Brunmer RJ, Arends JW, Deutz NE, Soeters PB: Glutamine and the preservation of gut integrity. Lancet 1993, 341:1363-1365.
31. Tremel H, Kienle B, Weilemann LS, Stehle P, Furst P: Glutamine dipeptide-supplemented parenteral nutrition maintains intestinal function in the critically ill. Gastroenterology 1994, 107:1595-1601.
32. Wischmeyer P, Pemberton JH, Phillips SF: Chronic pouchitis after ileal pouch-anal anastomosis: responses to butyrate and glutamine suppositories in a pilot study. May Clin Proc 1993, 68:978-981.
33. Jebb SA, Osborne RJ, Maughan TS, Mohideen N, Mack P, Mort D, Shelley MD, Elia P: 5-Fluorouracil and folinic acid-induced mucositis: no effect of oral glutamine supplementation. Br J Cancer 1994, 70:734-735.
34. Petersson B, von der Decken A, Vinnars E, Wemerman J: Long-term effets of postoperative total parenteral nutrition supplemented with glycylglutamine on subjective fatigue and muscle protein synthesis. Br J Surg 1994, 81:1520-1523.
35. Lipman TO: Bacterial translocation and enteral nutrition in humans: an outsider looks in. JPEN J Parenter Enteral Nutr 1995, 19:156-165.
36. Spaeth G, Specian RD, Berg RD, Deitch EA: Bulk prevents bacterial translocation induced by the oral administration of total parenteral nutrition solution. JPEN J Parenter Enteral Nutr 1990, 14:442-447.
37. Frankel W, Zhang W, Singh A, Bain A, Satchithanandam S, Klurfeld D, Rombeau J: Fiber: effect on bacterial translocation and intestinal mucin content. World J Surg 1995, 19:144-149.
38. Kueppers PM, Miller TA, Chen C-YK, Smith GS, Rodriguez LF, Moody FG: Effect of total parenteral nutrition plus morphine on bacterial translocation in rats. Ann Surg 1993, 217:286-292.
39. Illig KA, Ryan CK, Hardy D, Rhodes J, Locke W, Sax HC: Total parenteral nutrition-induced changes in gut mucosal function: atrophy alone is not the issue. Surgery 1992, 112:631-637.
40. Pappenheimer JR: On the coupling of membrane digestion with intestinal absorption of sugars and amino acids. Am J Physiol 1993, 265:G409-G417.
41. Brooks SG, May J, Sedman P, Tring I, Johnstone D, Mitchell CJ, Macfie J: Translocation of enteric bacteria in humans. Br J Surg 1993, 80:901-902.
42. Reed LL, Martin M, Manglano R, Newson B, Kocka F, Barrett J: Bacterial translocation following abdominal trauma in humans. Circ Shock 1994, 42:1-6.
43. Brathwaite CEM, Ross SE, Nagele R, Mure AJ, O'Malley KF, Garcia-Perez FA: Bacterial translocation occurs in humans after traumatic injury: evidence using immunofluorescence. J Trauma 1993, 34:586-589.
44. Deitch EA: Simple intestinal obstruction causes bacterial translocation in man. Arch Surg 1989, 124:699-701.
45. Sedman PC, Macfie J, Sagar P, Mitchell CJ, May J, Mancey-Jones B, Johnstone D: The prevalence of gut translocation in humans. Gastroenterology 1994, 107:643-649.
46. Elia M, Goren A, Behrens R, Barker RW, Neale G: Effect of total starvation and very low calorie diets on intestinal permeability in man. Clin Sci 1987, 73:205-210.
47. Hadfield RJ, Sinclair DG, Houldsworth PE, Evans TW: Effects of enteral and parenteral nutrition on gut mucosal permeability in the critically ill. Am J Respir Crit Care Med 1995, 152:1545-1548.
48. Rapp RP, Young B, Twyman D, Brevins BA, Haack D, Tibbs PA, Bean JR: The favorable effect of early parenteral feeding on survival in head-injury patients. J Neurosurg 1983, 58:906-912.
49. Young B, Ott L, Twyman D, Norton J, Rapp R, Tibbs P, Haack D, Brevins B, Dempsey R: The effect of nutrition support on outcome from severe head injury. J Neurosurg 1987, 67:668-676.
50. Moore FA, Moore EE, Jones TN, McCroskey BL, Peterson VM: TEN versus TPN following major abdominal trauma: reduced septic morbidity. J Trauma 1989, 29:916-922.
51. Moore EE, Jones TN: Benefits of immediate jejunostomy feeding after major abdominal trauma: a prospective, randomized study. J Trauma 1986, 26:874-881.
52. Muggia-Sullam M, Bower RH, Murphy RF, Jaffe SN, Fischer JE: Postoperative enteral vs parenteral nutrition: a matched prospective study. Am J Surg 1985, 149:106-112.
53. Moore FA, Feliciano DV, Adrassy RJ, McArdle AA, Berth RV, Morgenstein-Wagner TB, Kellum JM Jr, Welling RE, Moore EE: Early enteral feeding, compared with parenteral, reduces postoperative septic complications: the results of a meta-analysis. Ann Surg 1992, 216:172-183.
54. Heyland DK, Cook DJ, Guyatt GH: Enteral nutrition in the critically ill patient: a critical review of the evidence. Intensive Care Med 1993, 19:435-442.
55. Kudsk KA, Croce MA, Fabian TC, Menard G, Tolley EA, Poret A, Kuhl MR, Brown RO: Enteral versus parenteral feeding. Ann Surg 1992, 215:503-513.
56. Greene HC, McCabe DR, Merenstein GB: Protracted diarrhea and malnutrition in infancy: changes in intestinal morphology and disaccharidase activity during treatment with total intravenous nutrition or oral elemental diets. J Pediatr 1975, 87:695-704.
57. Aynsley-Green A, Lucas A, Lawson GR: Gut hormones and regulatory peptides in relation to enteral feeding, gastroenteritis and necrotizing enterocolitis in infancy. J Pediatr 1990, 117:524-532.
58. Lucas A, Aynsley-Green A, Bloom SR: Gut hormones and the first meals. Clin Sci 1981, 60:349-353.
59. Byrne TA, Persinger RL, Young LS, Ziegler TR, Wilmore DW: A new treatment for patients with short-bowel syndrome: growth hormone, glutamine, and a modified diet. Ann Surg 1995, 222:243-255.