Acute overdose of zolpidem (Stilnox®);AKUTE UBERDOSIERUNGEN MIT ZOLPIDEM (STILNOX®)

Schweizerische Medizinische Wochenschrift

Volumn 126, Issue 18, 1996, Pages 750-756

  Wyss, P A ^a,b   Radovanovic, D ^a   Meier Abt, P J ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b Schweizerisches Toxikologisches Informationszentrum   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

FLUMAZENIL; MIDAZOLAM; MIDAZOLAM MALEATE; TRIAZOLAM; ZOLPIDEM; ZOLPIDEM TARTRATE;

ARTICLE; COMA; HUMAN; INTOXICATION; MAJOR CLINICAL STUDY; SOMNOLENCE;

ADOLESCENT; ADULT; AGED; ANTIDOTES; COMA; FEMALE; FLUMAZENIL; HUMANS; HYPNOTICS AND SEDATIVES; MALE; MIDAZOLAM; MIDDLE AGED; OVERDOSE; PYRIDINES; RETROSPECTIVE STUDIES; TRIAZOLAM;

EID: 0029948016     PISSN: 00367672     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Langtry HD, Benfield P: Zolpidem: A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential. Drugs 1990; 40: 291-313.
2. Salva P, Costa J: Clinical pharmacokinetics and pharmacodynamics of zolpidem: Therapeutic implications. Clin Pharmacokinet 1995; 29: 142-153.
3. Garnier R, Guerault E, Muzard D, Azoyan P, Chaumetriffaud AE et al.: Acute zolpidem poisoning - analysis of 344 cases. Clin Toxicol 1994; 32: 391-404.
4. Karch FE, Lasagna L: Adverse reactions: a critical review. JAMA 1975; 234: 1236-1241.
5. Caravati EM, Bossart PJ: Demographic and electrocardiographic factors associated with severe tricyclic antidepressant toxicity. Clin Toxicol 1991; 29: 31-43.
6. Méram D, Descotes J: Intoxication aiguë par le zolpidem. Rev Med Interne 1989; 10: 466-467.
7. Bianchetti G, Dubruc C, Thiercelin JF, Bercoff E, Bouchet JL et al.: Clinical pharmacokinetics of zolpidem in various physiological and pathological conditions. In: Sauvanet JP, Langer SZ, Morselli PL (Hrsg): Imidazopyridines in sleep disorders: a novel experimental and therapeutic approach. New York: Raven Press, 1988: 155-163.
8. Iruela LM, Ibanes-Rojo V, Baca E: Zolpidem-induced macropsia in an anorexic woman. Lancet 1993; 342: 443-444.
9. Hoehns JD, Perry PJ: Zolpidem: A nonbenzodiazepine hypnotic for treatment of insomnia. Clin Pharm 1993; 12: 814-828.
10. Crome P, Ali C: Clinical features and management of self-poisoning with newer antidepressants. Med Toxicol 1986; 1: 411-420.
11. Marshall A, Moore K: Pulmonary disease after amitriptyline overdosage. Br Med J 1973; 289: 716-717.
12. Tracqui A, Kintz P, Mangin P: A Fatality Involving Two Unusual Compounds - Zolpidem and Acepromazine. Am J Forensic Med Pathol 1993; 14: 309-312.
13. Desager JP, Hulhoven R, Harvengt C, Hermann P, Guillet P: Possible interactions between zolpidem, a new sleep inducer, and chlorpromazine, a phenothiazine neuroleptic. Psychopharmacology 1988; 96: 63-66.
14. Patat A, Naef M, Van Gessel E, Forster A, Dubruc C, Rosenzweig P: Flumazenil antagonizes the central effects of zolpidem, an imidazopyridine hypnotic. Clin Pharmacol Ther 1994; 56: 430-436.
15. Martens F, Koppel C, Ibe K, Wagemann A, Tenczer J: Clinical experience with the benzodiazepine antagonist flumazenil in suspected benzodiazepine or ethanol poisoning. Clin Toxicol 1990; 28: 341-356.
16. Weinberg AD, Pals JK, Marinelli FC, Thibault GE: Oxazepam overdose associated with ethanol ingestion: Treatment with a benzodiazepine antagonist. Am J Crit Care 1994; 3: 464-466.
17. Meier PJ, Wyss PA, Radovanovic DI: Differential acute overdose toxicity of various benzodiazepine derivatives. Vet Hum Toxicol 1993; 35: 88.