Detection of poly(ADP-ribose) polymerase and its reaction product poly(ADP-ribose) by immunocytochemistry

Histochemical Journal

Volumn 28, Issue 5, 1996, Pages 391-395

  Küpper, Jan Heiner ^a   Van Gool, Léon ^a   Müller, Marcus ^a   Bürkle, Alexander ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; POLY(ADENOSINE DIPHOSPHATE RIBOSE);

ANIMAL CELL; ARTICLE; CELL CULTURE; DNA BINDING; IMMUNOHISTOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENE EXPRESSION; IMMUNOENZYME TECHNIQUES; MICE; POLY ADENOSINE DIPHOSPHATE RIBOSE; POLY(ADP-RIBOSE) POLYMERASES; RABBITS; RECOMBINANT FUSION PROTEINS;

ANIMALIA;

EID: 0029947874     PISSN: 00182214     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02331402     Document Type: Article

References (11)

1. ALTHAUS, F. R. & RICHTER, C. (1987) ADP-ribosylation of proteins. Enzymology and biological significance. Mol. Biol. Biochem. Biophys. 37, 1-237.
2. BOULIKAS, T. (1991) Relation between carcinogenesis, chromatin structure and poly(ADP-ribosylation). Anticancer Res. 11, 489-527.
3. BÜRKLE, A., CHEN, G., KÜPPER, J.-H., GRUBE, K. & ZELLER, W. J. (1993) Increased poly(ADP-ribosyl)ation in intact cells by cisplatin treatment. Carcinogenesis 14, 559-61.
4. DE MURCIA, G. & MÉNISSIER-DE MURCIA, J. (1994) Poly(ADP-ribose) polymerase: a molecular nick-sensor. Trends Biochem. Sci. 19, 172-6.
5. DING, R., POMMIER, Y., KANG, V. H. & SMULSON, M. (1992) Depletion of poly(ADP-ribose) polymerase by antisense RNA expression results in a delay in DNA strand break rejoining. J. Biol. Chem. 267, 12804-12.
6. KAWAMITSU, H., HOSHINO, H., OKADA, H., MIWA, M., MOMOI, H. & SUGIMURA, T. (1984) Monoclonal antibodies to poly(adenosine diphosphate ribose) recognize different structures. Biochemistry 23, 3771-7.
7. KÜPPER, J.-H., DE MURCIA, G. & BÜRKLE, A. (1990) Inhibition of poly(ADP-ribosyl)ation by overexpressing the poly(ADP-ribose) polymerase DNA-binding domain in mammalian cells. J. Biol. Chem. 265, 18721-4.
8. KÜPPER, J.-H., MÜLLER, M., JACOBSON, M. K., TATSUMI-MIYAJIMA, J., COYLE, D. L., JACOBSON, E. L. & BÜRKLE, A. (1995) Trans-dominant inhibition of poly(ADP-ribosyl)ation sensitizes cells against γ-irradiation and N-methyl-N′-nitro-N-nitrosoguanidine but does not limit DNA replication of a polyoma virus replicon. Mol. Cell. Biol. 15, 3154-63.
9. NICHOLSON, D. W., ALI, A., THORNBERRY, N. A., VAILLANCOURT, J. P., DING, C. K., GALLANT, M., GAREAU, Y., GRIFFIN, P. R., LABELLE, M., LAZEBNIK, Y. A., MUNDAY, N. A., RAJU, S. M., SMULSON, M. E., YAMIN, T.-T., YU, V. L. & MILLER, D. K. (1995) Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 376, 37-43.
10. SIMONIN, F., BRIAND, J.-P., MULLER, S. & DE MURCIA, G. (1991) Detection of poly(ADP ribose) polymerase in crude extracts by activity-blot. Anal. Biochem. 195, 226-31.
11. TEWARI, M., QUAN, L. T., O'ROURKE, K., DESNOYERS, S., ZENG, Z., BEIDLER, D. R., POIRIER, G. G., SALVESEN, G. S. & DIXIT, V. M. (1995) Yama/CPP32β, a mammalian homolog of CED-3, is a CRMA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell 81, 801-9.