Evidence for an increased rate of bacterial infections in liver transplant patients with cytomegalovirus infection

Clinical Transplantation

Volumn 10, Issue 2, 1996, Pages 224-231

  Van Den Berg, A P ^a   Klompmaker, I J ^a   Haagsma, E B ^a   Peeters, P M J G ^a   Meerman, L ^a   Verwer, R ^a   The, T H ^a   Slooff, M J H ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Cytomegalovirus; Liver transplantation; Opportunistic infections

Indexed keywords

AMPHOTERICIN B; AZATHIOPRINE; CEFOTAXIME; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; GANCICLOVIR; METHYLPREDNISOLONE; POLYMYXIN B; PREDNISOLONE; THYMOCYTE ANTIBODY; TOBRAMYCIN; VIRUS ANTIGEN;

ADULT; AGED; ARTICLE; BACTERIAL INFECTION; CYTOMEGALOVIRUS INFECTION; DISEASE COURSE; FEMALE; GRAFT VERSUS HOST REACTION; GRAM POSITIVE COCCI; HUMAN; HUMAN CELL; INCIDENCE; INTRAVENOUS DRUG ADMINISTRATION; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MORBIDITY; OPPORTUNISTIC INFECTION; ORAL DRUG ADMINISTRATION; PATIENT MONITORING; PRIORITY JOURNAL; RISK; SEROLOGY; SYMPTOM;

ADOLESCENT; ADULT; AGED; ANTIBIOTIC PROPHYLAXIS; ANTIGENS, VIRAL; BACTERIAL INFECTIONS; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; DISEASE SUSCEPTIBILITY; ENTEROCOCCUS; FEMALE; GRAFT REJECTION; GRAM-POSITIVE BACTERIAL INFECTIONS; HUMANS; LIVER TRANSPLANTATION; MALE; MIDDLE AGED; OPPORTUNISTIC INFECTIONS; RETROSPECTIVE STUDIES; RISK FACTORS; STAPHYLOCOCCAL INFECTIONS; STREPTOCOCCAL INFECTIONS; SURVIVAL RATE; TIME FACTORS; VIREMIA;

EID: 0029947327     PISSN: 09020063     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. KUSNE S, DUMMER JS, SING N, et al. Infections after liver transplantation: an analysis of 101 consecutive cases. Medicine (Baltimore) 1988: 67: 132.
2. STRATTA RJ, SHEAFFER MS, MARKIN RS, et al. Cytomegalovirus infection and disease after liver transplantation: an overview. Dig Dis Sci 1992: 37: 673.
3. CHATTERJEE SN, FIALA M, WEINER J, STEWART JA, STACEY B, WARNER N. Primary cytomegalovirus and opportunistic infections. JAMA 1978: 240: 2446.
4. RAND KH, POLLARD RP, MERIOAN TC. Increased pulmonary superinfections in cardiac transplant recipients undergoing primary cytomegalovirus infection. N Engl J Med 1978: 298: 951.
5. RUBIN RH, WOLFSON JS, COSIMI AB, TOLKOFF-RUBIN NE. Infection in the renal transplant recipient. Am J Med 1981: 70: 405.
6. SIMMONS RL, MATAS AJ, RATTAZZI LC, BALFOUR HH, JR, HOWARD RJ, NAJARIAN JS. Clinical characteristics of the lethal cytomegalovirus infection following renal transplantation. Surgery 1977: 82: 537.
7. VAN DEN BERG AP, KLOMPMAKER IJ, HAAGSMA EB, et al. Antigenemia in the diagnosis and monitoring of active CMV infection after liver transplantation. J Infect Dis 1991: 164: 265.
8. THE TH, VAN DER PLOEG M, VAN DEN BERG AP, VLIEGER AM, VAN DER GIESSEN M, VAN SON WJ. Direct detection of cytomegalovirus in peripheral blood leukocytes: a review of the antigenemia assay and polymerase chain reaction. Transplantation 1992: 54: 193.
9. CHOUS S. Molecular diagnostic techniques for CMV infection: p183. In: MICHELSON S, PLOTKIN SA (eds.): Multidisciplinary approach in understanding cytomegalovirus disease. Elsevier, Amsterdam, 1993.
10. BITCH A, KIRCHNER H, DUPKE R, BEIN G. Cytomegalovirus transcripts in peripheral blood leukocytes of actively infected transplant detected by reverse transcription-polymerase chain reaction. J Infect Dis 1993: 167: 740.
11. MAZZULI T, RUBIN RH, FERRARO MJ, et al. Cytomegalovirus antigenemia - clinical correlations in transplant recipients and in persons with AIDS. J Clin Microbiol 1993: 31: 2824.
12. ENRICE A, JORDAN MC, CHACE BA, FLETCHER C, CHINNOCK BJ, BALFOUR JR., HH. Ganciclovir treatment of cytomegalovirus disease in transplant recipients and other immunocompromised hosts. JAMA 1987: 257: 3082.
13. PAYA CV, HERMANS PE, SMITH TF, et al. Efficacy of ganciclovir in liver and kidney transplant recipients with severe cytomegalovirus infection. Transplantation 1988: 46: 82.
14. HIBBERT PL, TOLKOFF-RUBIN NE, COSIMI AB, et al. Symptomatic cytomegalovirus disease in the cytomegalovirus antibody positive renal transplant recipient treated with OKT3. Transplantation 1992: 53: 68.
15. KLOMPMAKER IJ, HAAGSMA EB, Gouw ASH, VERWER R, SLOOFF MJH. Azathioprine and prednisolone immunosuppression versus maintenance triple therapy including cyclosporine for orthotopic liver transplantation. Transplantation 1989: 48: 814.
16. ROSMAN C, KLOMPMAKER IJ, BONSEL G, BLEICHRODT RP, ARENDS JWA, SLOOFF MJH. The efficacy of selective bowel decontamination as infection prevention after transplantation. Transplant Proc 1993: 22: 1554.
17. VAN DER Bu W, SCHIRM J, TORENSMA R, VAN SON WJ. TEGZEES AM, THE TH. Comparison of viremia and antigenemia for detection of cytomegalovinis in blood. J Clin Microbiol 1988: 26: 2531.
18. SCHIRM J, TIMMERIJE W, VAN DER BIJ W, et al. Rapid detection of infectious cytomegalovinis in blood with the aid of monoclonal antibodies. J Med Virol 1987: 23: 31.
19. VAN DER BERG AP, VAN SON WJ, HAAGSMA EB, et al. Prediction of recurrent cytomegalovirus disease after treatment with ganciclovir in solid organ transplant recipients. Transplantation 1993: 55: 847.
20. VAN DER GEESSEN M, VAN DER BERG AP, VAN DER Bu W, POSTMA S, VAN SON WJ, THE TH. Quantitative measurement of CMV-specific IgG and IgM antibodies in relation to CMV antigenemia and disease activity in kidney transplantation with active CMV infection. Clin Exp Immunol 1990: 80: 56.
21. PAYA CV, MARIN E, KEATING M, et al. Solid organ transplantation: results and implications of acyclovir use in liver transplants. J Med Virol 1993: Suppl 1: 123.
22. PAYA CV, WIESNER RH, HERMANS PE, et al. Risk factors for cytomegalovirus and severe bacterial infections following liver transplantation: a progressive multivariate time-dependent analysis. J Hepatol 1993: 18: 185.
23. PRENTICE HG, GLUCKMAN E, POWLES RL, et al. Impact of long-term acyclovir on cytomegalovirus infection and survival after allogeneic bone marrow transplantation. Lancet 1994: 343: 749.
24. KAPASI K, RICE GPA. Role of the monocyte in cytomegalovirus-mediated immunosuppression in vitro. J Infect Dis 1986: 154: 881.
25. BALE JF, O'NEIL ME, GRETNER T. The interaction of murine cytomegalovirus with murine neutrophils: effect on migratory and phagocytic activities. J Leukocyte Biol 1985: 38: 723.