Antiemetic efficacy of prophylactic ondansetron in laparoscopic cholecystectomy: A randomised, double-blind, placebo-controlled trial

Anaesthesia

Volumn 51, Issue 1, 1996, Pages 52-55

  Koivuranta, M K ^a   Laara E ^b   Ryhanen P T ^a  

^a OULU UNIVERSITY HOSPITAL   (Finland)

^b UNIVERSITY OF OULU   (Finland)

Author keywords

Complications, postoperative; nausea, vomiting; Pharmacology; ondansetron; Surgery; cholecystectomy, laparoscopic

Indexed keywords

ANTIEMETIC AGENT; ONDANSETRON;

ADULT; AGED; ARTICLE; CHOLECYSTECTOMY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; GENERAL ANESTHESIA; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; LAPAROSCOPIC SURGERY; MAJOR CLINICAL STUDY; MALE; NAUSEA; PREMEDICATION; PROPHYLAXIS; RANDOMIZED CONTROLLED TRIAL; VOMITING;

ADULT; AGED; ANALGESICS, OPIOID; ANTIEMETICS; CHOLECYSTECTOMY, LAPAROSCOPIC; DOUBLE-BLIND METHOD; DROPERIDOL; FEMALE; HUMANS; MALE; MIDDLE AGED; NAUSEA; ONDANSETRON; OXYCODONE; PREMEDICATION; VOMITING;

EID: 0029947295     PISSN: 00032409     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2044.1996.tb07654.x     Document Type: Article

References (14)

1. WATCHA MF, WHITE PF. Postoperative nausea and vomiting. Its etiology, treatment and prevention. Anesthesiology 1992; 77: 162-84.
2. 3 receptor antagonists in the prophylaxis of acute vomiting induced by moderately emetogenic chemotherapy - a randomised study. European Journal of Cancer 1993. 29A: 1669-72.
3. DICATO MA, FREEMAN AJ. Experience with ondansetron in chemotherapy- and radiotherapy-induced emesis. European Journal of Anaesthesiology 1992; 9(Suppl. 6): 19-24.
4. 3 receptor antagonist. Anesthesia and Analgesia 1991; 72: 751-5.
5. SUEN TKL, GIN TA, CHEN PP, ROWBOTTOM YM, CRITCHLEY LAH, RAY AK. Ondansetron 4 mg for the prevention of nausea and vomiting after minor laparoscopic gynaecological surgery. Anaesthesia and Intensive Care 1994; 22: 142-6.
6. JOSLYN AF. Ondansetron, clinical development for postoperative nausea and vomiting: current studies and future directions. Anaesthesia 1994, 49(Suppl.): 34-7.
7. CUNNINGHAM AJ, BRULL SJ. Laparoscopic cholecystectomy: anesthetic implications. Anesthesia and Analgesia 1993; 76: 1120-33.
8. GARDNER MJ, ALTMAN DG. Statistics wiith confidence: Confidence Intervals and Statistical Guidelines. London: British Medical Journal, 1989: 29-30.
9. CAMU F, LAUWERS MH, VERBESSEM D. Incidence and aetiology of postoperative nausea and vomiting. European Journal of Anaesthesiology 1992; 9(Suppl. 6): 25-31.
10. MADSEN MR, JENSEN KEJ. Postoperative pain and nausea after laparoscopic cholecystectomy. Surgical Laparoscopy and Endoscopy 1992; 2: 303-5.
11. KORTTILA K. The study of postoperative nausea and vomiting. British Journal of Anaesthesia 1992; 69(Suppl 1): 20-3
12. ROWBOTHAM DJ. Current management of postoperative nausea and vomiting. British Journal of Anaesthesia 1992; 69(Suppl. 1): 46-59.
13. KOVAC A, McKENZIE R, O'CONNOR T, DUNCALF D, ANGEL J, GRATZ I, FAGRAEUS I, McLESKEY C, JOSLYN AF. Prophylactic intravenous ondansetron in female outpatients undergoing gynaecological surgery, a multicentre dose-comparison study. European Journal of Anaesthesiology 1992; 9(Suppl. 6): 37-47.
14. PEARMAN MH. Single dose intravenous ondansetron in the prevention of postoperative nausea and vomiting. Anaesthesia 1994; 49(Suppl.): 11-5.