Prospective neuropsychological assessment of nondemented patients with biopsy proven senile plaques

Neurology

Volumn 46, Issue 2, 1996, Pages 425-429

  Mackenzie, Ian R A ^a,b   McLachlan, Richard S ^a   Kubu, Cynthia S ^a   Miller, Laurie A ^a  

^a LONDON HEALTH SCIENCES CENTRE   (Canada)

^b TORONTO WESTERN HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; BRAIN BIOPSY; CHROMOSOME 21; COGNITIVE DEFECT; DEMENTIA; FEMALE; GENE MUTATION; HUMAN; INTRACTABLE EPILEPSY; MAJOR CLINICAL STUDY; MALE; NEUROPSYCHOLOGICAL TEST; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK ASSESSMENT; SENILE PLAQUE;

EID: 0029947270     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.46.2.425     Document Type: Article

References (53)

1. Glenner GG, Wong CW. Alzheimer disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem Biophys Res Commun 1984;120: 885-890.
2. Masters CL, Simms G, Weinman NA, Multhaup G, McDonald BL, Beyreuther K. Amyloid plaque core protein in Alzheimer disease and Down syndrome. Proc Natl Acad Sci USA 1985;82: 4245-4249.
3. Yamaguchi H, Haga C, Hirai S, Nakazato Y, Kosaka K. Distinctive, rapid and easy labelling of diffuse plaques in the Alzheimer brains by a new methenamine silver stain. Acta Neuropathol 1990;798:569-572.
4. Yamaguchi H, Hirai S, Morimatsu M, Shoji M, Harigaya Y. Diffuse type of senile plaques in the brains of Alzheimer-type dementia. Acta Neuropathol 1988;77:113-119.
5. Goldgaber D, Lerman MI, McBride OW, Saffiotti U, Gajusek DC. Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease. Science 1987; 235:877-880.
6. Kang J, Lemaire HG, Unterbeck A, et al. The precursor of Alzheimer's disease amyloid A4 protein resembles a cell surface receptor. Nature 1987;325:733-736.
7. Kitaguchi N, Takahashi Y, Tokushima Y, Shiojiri S, Ito H. Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity. Nature 1988;311:530-532.
8. Robakis NK, Ramakrishna N, Wolfe G, Wisniewski HM. Molecular cloning and characterization of a cDNA encoding the cerebrovascular and neuritic plaque amyloid peptides. Proc Natl Acad Sci USA 1987;84:4190-4194.
9. Tanzi RE, Gusella JF, Watkins PC, et al. Amyloid β protein gene: cDNA, mRNA distribution and genetic linkage near the Alzheimer's locus. Science 1987;235:880-884.
10. Card JP, Meade RP, Davis LG. Immunocytochemical localization of the precursor protein for β-amyloid in the rat central nervous system. Neuron 1988;1:835-846.
11. Goedert M. Neuronal localization of amyloid beta protein precursor mRNA in normal human brain and in Alzheimer's disease. EMBO J 1987;6:3627-3632.
12. Mita S, Schon EA, Herbert J. Widespread expression of amyloid beta-protein precursor gene in rat brain. Am J Pathol 1989;134:1253-1261.
13. Shivers BD, Hilbich C, Multhaup G, Salbaum M, Beyreuther K, Seeburg PH. Alzheimer's disease amyloidogenic glycoprotein: expression pattern in rat brain suggests role in cell contact. EMBO J 1988;7:1365-1370.
14. Kowall NW, Beal MF, Busciglio J, Duffy LK, Yankner BA. An in vivo model for the neurodegenerative effects of β amyloid and protection by substance P. Proc Natl Acad Sci USA 1991; 88:7247-7251.
15. Yankner BA, Duffy LK, Kirschner DA. Neurotrophic and neurotoxic effects of amyloid β protein: reversal by tachykinin neuropeptides. Science 1990;250:279-282.
16. Joachim CL, Selkoe DJ. The seminal role of β-amyloid in the pathogenesis of Alzheimer disease. Alzheimer Dis Assoc Disord 1992;6:7-34.
17. Selkoe DJ. The molecular pathology of Alzheimer's disease. Neuron 1991;6:487-498.
18. Goate A, Chartier-Harlin M-C, Mullan M, et al. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 1991;349:704-706.
19. Naruse S, Igarashi S, Kobagashi H, et al. Mis-sense mutation Val→Ile in exon 17 of amyloid precursor protein gene in Japanese familial Alzheimer's disease. Lancet 1991;337:978-979.
20. Van Duijn CM, Hendricks L, Cruts M, Hardy JA, Hofman A, Van Broechkoven C. Amyloid precursor protein gene mutation in early onset Alzheimer's disease. Lancet 1991;377:978.
21. Cai XD, Golde TE, Younkin SG. Release of excess amyloid β protein from a mutant amyloid β protein precursor. Science 1991;259:514-516.
22. Mann DMA. The pathological association between Down syndrome and Alzheimer disease. Mech Ageing Dev 1988;43:99-136.
23. Oliver C, Holland AJ. Down's syndrome and Alzheimer's disease - a review. Psychol Med 1986;16:307-322.
24. Whalley LJ. The dementia of Down's syndrome and its relevance to aetiological studies of Alzheimer's disease. Ann NY Acad Sci 1982;396:39-53.
25. Rumble B, Retallack R, Hilbich C, et al. Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease. N Engl J Med 1989;320:1446-1451.
26. Mann DMA, Esiri MM. The pattern of acquisition of plaques and tangles in the brains of patients under 50 years of age with Down's syndrome. J Neurol Sci 1989;89:169-179.
27. Motte J, Williams RS. Age-related changes in the density and morphology of plaques and neurofibrillary tangles in Down syndrome brain. Acta Neuropathol 1989;77:535-546.
28. Spargo E, Luthert PJ, Jonata I, Lantos PL. βA4 deposition in the temporal cortex of adults with Down's syndrome. J Neurol Sei 1992;111:26-32.
29. Mann DM, Jones D, South PW, Snowden JS, Neary D. Deposition of amyloid β protein in non-Alzheimer dementias: evidence for a neuronal origin of parenchymal deposits of β protein in neurodegenerative disease. Acta Neuropathol 1992;83: 415-419.
30. Mastaglia F, Masters CL, Beyreuther K, Kakulas BA. Deposition of amyloid (A4) protein in the cerebral cortex in Parkinson's disease. Alzheimer Dis Assoc Disord 1988;2:254.
31. Tan N, Mastaglia F, Masters CL, Beyreuther K, Kakulas BA. Amyloid (A4) deposition in brain in progressive supranuclear palsy (PSP). Alzheimer Dis Assoc Disord 1988;2:264.
32. Arriagada PV, Marzloff BA, Bradley TH. Distribution of Alzheimer-type pathologic changes in non-demented elderly individuals matches the pattern in Alzheimer's disease. Neurology 1992;42:1681-1688.
33. Davies L, Wolska B, Hilbich C, et al. A4 amyloid protein deposition and the diagnosis of Alzheimer's disease: prevalence in aged brains determined by immunohistochemistry compared with conventional neuropathologic techniques. Neurology 1988;38:1688-1693.
34. Mackenzie IRA. Senile plaques do not progressively accumulate with normal aging. Acta Neuropathol 1994;87:520-525.
35. Mann DMA, Tucker CM, Yates PO. The topographic distribution of senile plaques and neurofibrillary tangles in the brains of non-demented persons of different ages. Neuropathol Appl Neurobiol 1987;13:123-139.
36. Price JL, Davis PB, Morris JC, White DL. The distribution of tangles, plaques and related immunohistochemical markers in healthy aging and Alzheimer's disease. Neurobiol Aging 1991; 12:295-312.
37. Tomlinson BE, Blessed G, Roth M. Observations on the brains of non-demented old people. J Neurol Sci 1968;7:331-356.
38. Ulrich J. Alzheimer changes in nondemented patients younger than sixty-five: possible early stages of Alzheimer's disease and senile dementia of Alzheimer type. Ann Neurol 1985;17:273-277.
39. Mackenzie IRA, Miller LA. Senile plaques in temporal lobe epilepsy. Acta Neuropathol 1994;87:504-510.
40. Corkin S. Some relationships between global amnesias and the memory impairments in Alzheimer's disease. In: Corkin S, Davis KL, Growdon JH, Usdin E, eds. Alzheimer's disease: a report of progress in research. New York: Raven Press, 1982: 149-164.
41. Hier B, Hagenlocker K, Shindler AG. Language disintegration in dementia: effects of etiology and severity. Brain Lang 1985; 25:117-133.
42. Hill RD, Storandt M, LaBarge E. Psychometric discrimination of moderate senile dementia of the Alzheimer type. Arch Neurol 1992;49:377-380.
43. Lezak MD. Neuropsychological assessment. New York: Oxford University Press, 1983:180-184.
44. Mendez MF, Mendez MA, Martin R, Smyth KA, Whitehouse PJ. Complex visual disturbances in Alzheimer's disease. Neurology 1990;40:439-443.
45. Whitehouse PJ, Lerner A, Hedera P. Dementia. In: Heilman KM, Valenstein E, eds. Clinical neuropsychology. New York: Oxford University Press, 1993:603-645.
46. Wechsler D. WAIS-R manual. New York: Psychological Corporation, 1981.
47. Wechsler DA. A standardized memory scale for clinical use. J Psychol 1945;19:87-95.
48. Rey A. L'examen psychologique dans les cas d'encephalopathie traumatique. Arch Psychol 1941;28:286-290.
49. Kaplan EF, Goodglass H, Weintraub S. The Boston naming test (2nd ed). Philadelphia: Lea & Febiger, 1983.
50. Thurstone LL. Primary mental abilities. Chicago: University of Chicago Press, 1938.
51. Folstein MF, Folstein SE, McHugh PR. Mini-Mental State. J Psych Res 1975;12:189-198.
52. Mattis S. Dementia rating scale. Odessa, Florida: Psychological Assessment Resources, 1988.
53. Delaere P, Duyckaerts C, Masters C, Beyreuther K, Piette F, Hauw JJ. Large amounts of neocortical βA4 deposits without neuritic plaques nor tangles in a psychometrically assessed, non-demented person. Neurosci Lett 1990;116:87-93.