D-mannose dimer introduced human recombinant interleukin-1α, NEO IL-1α, exhibits altered tissue distribution in mice

Journal of Interferon and Cytokine Research

Volumn 16, Issue 4, 1996, Pages 333-336

  Onozaki, Kikuo ^a  

^a NAGOYA CITY UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DIMER; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1ALPHA; MANNOSE; RECOMBINANT INTERLEUKIN 1ALPHA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG LIVER LEVEL; DRUG RECEPTOR BINDING; DRUG TISSUE LEVEL; FEMALE; GLYCOSYLATION; HEART; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TISSUE DISTRIBUTION;

EID: 0029947247     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/jir.1996.16.333     Document Type: Article

References (4)

1. OPPENHEIM, J.J., KOVACS, E.J., MATSUSHIMA, K., and DURUM, S.K. (1986). There is more than interleukin 1. Immunol. Today 7, 45-56.
2. DINARELLO, C.A. (1991). Interleukin-1 and interleukin-1 antagonism. Blood 77, 1627-1652.
3. DINARELLO, C.A., and WOLFF, S.M. (1993). The role of interIeukin-l in disease. N. Engl. J. Med. 328, 106-113.
4. KLAPPROTH, J., CASTELL, J., GEIGER, T., ANDUS, T., and HEINRICH, P.C. (1989). Fate and biological action of human recombinant interleukin 1β in the rat m vivo. Eur. J. Immunol. 19, 1485-1490.