Decreased growth hormone receptor expression in long bones from toothless (osteopetrotic) rats and restoration by treatment with colony-stimulating factor-1

Growth Factors

Volumn 13, Issue 1-2, 1996, Pages 1-10

  Symons, Anne L ^a   Mackay, Carole A ^b   Leong, Kim ^a   Hume, David A ^a   Waters, Michael J ^a   Marks Jr , Sandy C ^b  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

CSF 1; GH receptor; Long bones; Osteopetrotic

Indexed keywords

COLONY STIMULATING FACTOR 1; GROWTH HORMONE RECEPTOR;

ADIPOCYTE; ALBERS SCHOENBERG DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; BONE MARROW; BONE MARROW CELL; CARTILAGE; CELL MEMBRANE; CELL NUCLEUS; CELL SUBPOPULATION; CONTROLLED STUDY; EPIPHYSEAL CARTILAGE; ERYTHROID CELL; GRANULOCYTE; HOMOZYGOTE; IMMUNOCYTOCHEMISTRY; LONG BONE; LYMPHOCYTE; MACROPHAGE; MEGAKARYOCYTE; MONONUCLEAR CELL; NONHUMAN; OSSIFICATION; OSTEOCLAST; OSTEOLYSIS; PRIORITY JOURNAL; RAT; RECEPTOR DENSITY; TIBIA; TISSUE DISTRIBUTION;

ANIMALIA;

EID: 0029946781     PISSN: 08977194     EISSN: None     Source Type: Journal    
DOI: 10.3109/08977199609034562     Document Type: Article

References (45)

1. Aharinejad, S., Marks, S.C. Jr., Böck, P., Mason-Savas, A., MacKay, C.A., Larson, E.K., Jackson, M.E., Luftensteiner, M. and Wiesbauer, E. (1995) CSF-1 treatment promotes angiogenesis in the metaphysis of osteopetrotic (toothless, tl) rats. Bone 16, 315-324.
2. Badolato, R., Bond, H., Valerio, G., Petrella, A., Morrone, G., Waters, M.J., Venuta, S. and Tenore, A. (1994) Differential expression of surface membrane GH receptor on human peripheral blood lymphocytes detected by dual fluorochrome flow cytometry. J. Clin. Endocrinol. Metab. 79, 984-990.
3. Barnard, R., Bundesen, P.G., Rylatt, D.B. and Waters, M.J. (1984) Monoclonal antibodies to the growth hormone receptor: Production and characterisation. Endocrinology 115, 1805-1813.
4. Barnard, R., Bundesen, P.G., Rylatt, D.B. and Waters, M.J. (1985) Evidence from the use of monoclonal antibody probes for structural heterogeneity of the growth hormone receptor. Biochem. J. 231, 459-468.
5. Barnard, R., Haynes, K.M., Werther, G.A. and Waters, M.J. (1988) The ontogeny of growth hormone receptors in the rabbit tibia. Endocrinology 122, 2562-2569.
6. Barnard, R., Ng, K.W., Martin, T.J. and Waters, M.J. (1991) Growth hormone (GH) receptors in clonal osteoblast-like cells mediate a mitogenic response to GH. Endocrinology 128, 1459-1464.
7. Cotton, W.R. and Gaines, J.F. (1974) Unerupted dentition secondary to congenital osteopetrosis in the Osborne-Mendel rat. Proc. Soc. Exp. Biol. Med. 146, 554-561.
8. Garcia-Aragon, J., Lobie, P.E., Muscat, G.E.O., Gobius, K.S., Norstedt, G. and Waters, M.J. (1992) Prenatal expression of the growth hormone (GH) receptor/binding protein in the rat: A role of GH in embryonic and fetal development? Development 114, 869-876.
9. Gelato, M.C. (1993) Growth hormone-insulin-like growth factor 1 and immune function. Trends Endocrinol. Metals. 4, 106-110.
10. Halenbeck, R., Kawasaki, E., Wrin, J. and Koths, K. (1989) Renaturation and purification of biologically active recombinant human macrophage colony-stimulating factor expressed in E. coli. Biotechnology 7, 710-715.
11. Horowitz, M.C., Einhorn, T.A., Philbrick, W. and Jilka, R.L. (1989) Functional and molecular changes in colony stimulating factor secretion by osteoblasts. Connec. Tiss. Res. 20, 159-168.
12. Hume, D.A., Robinson A.P., Macpherson, G.C. and Gordon, S. (1983) The mononuclear phagocyte system of the mouse defined by immunohistochemical localisation of antigen F4/80. The relationship between Langerhans cells, reticular cells and dendritic cells in lymphoid and haematopoietic cells. J. Exp. Med. 158, 1522-1536.
13. Isaksson, O.G.P., Lindahl, A., Nilsson, A.L. and Isgaard, J. (1987) Mechanism of the stimulatory effect of growth hormone on longitudinal bone growth. Endocr. Rev. 8, 426-438.
14. Kelley, K.W. (1989) Growth hormone, lymphocytes and macrophages. Biochem Pharmacol. 38, 705-713.
15. Ladner, M.B., Martin, G.A., Noble, J.A., Nikolof, D.M., Tal, R., Kawasaki, E.S. and White, T.J. (1987) Human CSF-1: Gene structure and alternative splicing of mRNA precursors. EMBO J. 6, 2693-2698.
16. Lian, J.B. and Marks, S.C. Jr. (1990) Osteopetrosis in the rat: coexistence of reductions in osteocalcin and bone resorption. Endocrinology 126, 955-962.
17. Lobie, P.E., Garcia-Aragon, J., Wang, B.S., Baumbach, W.R. and Waters, M.J. (1992) Cellular localisation of the growth hormone binding protein in the rat. Endocrinology 130, 3057-3065.
18. Lobie, P.E., Barnard, R. and Waters, M.J. (1991) The nuclear GH receptor/binding protein. J. Biol Chem. 266, 22645-22652.
19. Lobie, P.E., Wood, T.J., Chen, C.-M. Waters, M.J. and Norstedt, G. (1994a) Nuclear translocation and anchorage of the GH receptor. J. Biol. Chem. 269, 31735-31746.
20. Lobie, P.E., Mertani, H., Morel, G., Morales-Bustos, O., Norstedt, G. and Waters, M.J. (1994b) Receptor mediated nuclear translocation of GH. J. Biol. Chem. 269, 21330-21339.
21. Lobie, P.E., Wood, T.J., Sliva, D., Billestrup, N., Waters, M.J., Enberg, B. and Norstedt, G. (1994c) The cellular mechanism of GH signal translocation. Acta Paediatrics. Suppl. 406, 39-46.
22. Madsen, K., Friberg, U., Roos, P., Edén, S. and Isaksson, O. (1983) Growth hormone stimulates the proliferation of cultured chondrocytes from rabbit ear and rat rib growth cartilage. Nature 304, 545-549.
23. Marks, S.C. Jr. (1977) Osteopetrosis in the toothless (tl) rat: Presence of osteoclasts but failure to respond to parathyroid extract or to be cured by infusion of spleen or bone marrow cells from normal littermates. Am. J. Anat. 149, 289-297.
24. Marks, S.C. Jr. (1992) Congenital Osteopetrosis in Mammals - new windows on osteoclast biology. In: H. Slavkin and P. Price, eds, Chemistry and Biology of Mineralized Tissues. Elsevier Science, Amsterdam, pp. 475-482.
25. Marks, S.C. Jr. (1994) Osteopetrosis. Curr. Opin. Orthoped. 5, 39-42.
26. Marks, S.C. Jr., Wojtowicz, A., Szperl, M., Urbanowska, E., MacKay, C.A., Wiktor-Jedrzejczak, W., Stanley, E.R. and Aukerman, S.L. (1992) Administration of colony stimulating factor-1 corrects some macrophage, dental, and skeletal defects in an osteopetrotic mutation (toothless, tl) in the rat. Bone 13, 89-93.
27. Marks, S.C. Jr., MacKay, C.A., Jackson, M.E., Larson, E.K., Cielinski, M.J., Stanley, E.R. and Aukerman, S.L. (1993) The skeletal effects of colony-stimulating factor-1 in toothless (osteopetrotic) rats: persistent metaphyseal sclerosis and the failure to restore the subepiphyseal osteoclasts. Bone 14, 675-680.
28. Merchav, S., Tatarsky, I. and Hochberg, Z. (1988) Enhancement of human granulopoiesis in vitro by biosynthetic insulin-like growth factor 1/somatomedin C and human growth hormone. J. Clin. Invest. 18, 791-797.
29. Mertani, H. and Morel, G. (1995) In situ gene expression of GH receptor and GHBP in adult male rat tissues. Mol. Cell. Endo. (in press).
30. Mertani, H.C., Delahage-Zervas M.C., Martini, J.R, Postel-Vinay, M.C., Morel, G. (1995) Localisation of GH receptor mRNA in human tissues. Endocrine 3, 135-142.
31. Milhaud, G., Labat, M.L., Litwin, I., Moricard, Y., Moutier, R., Rimbaut, C., Buffe, D. and Juster, M. (1981) Osteopetrorickets: A new congenital bone disorder. Metab. Bone Dis. 3, 91-97.
32. Ralph, P., Warren, M.K., Lee, M.T., Csejtey, J., Weaver, J.F., Broxmeyer, H.E., Williams, D.E., Stanley, E.R. and Kawasaki, E.S. (1986) Inducible production of human macrophage growth factor, CSF-1. Blood 68, 633-639.
33. Seifert, M.F. (1994) Lack of evidence for rickets in the osteopetrotic rat mutation, toothless. J. Bone Miner. Res. 9, 1813-1821.
34. Seifert, M.F. and Pedigo, L.M. (1992) Decreased osteoblast number and function in the osteopetrotic toothless rat mutation. Bone 13, A30.
35. Seifert, M.F., Popoff, S.N. and Marks, S.C. Jr. (1988) Skeletal biology in the toothless (osteopetrotic) rat. Am. J. Anal. 183, 158-165.
36. Seifert, M.F., Popoff, S.N., Jackson, M.E., Mackay, C.A., Cielinski, M. and Marks, S.C. Jr. (1993) Experimental studies of osteopetrosis in laboratory animals. Clin. Orthop. 294, 23-33.
37. Shalhoub, V., Jackson, M., Lian, J.B., Stein, G.S. and Marks, S.C. Jr. (1991) Gene expression during skeletal development in three osteopetrotic rat mutations: Evidence for osteoblast abnormalities. J. Biol. Chem. 266, 9847-9856.
38. Shalhoub, V., Bettencourt. B., Jackson, M.E., Mackay, C.A., Glincher, M.J., Marks, S.C. Jr, Stein, G.S. and Lian, J.B. (1994) Abnormalities of phosphoprotein gene expression in three osteopetrotic rat mutations: elevated mRNA transcripts, protein synthesis and accumulation in bone of mutant animals. J. Cell Physiol. 158, 110-120.
39. Strobl, J.S. and Thomas, M.J. (1994) Human growth hormone. Pharmacol. Rev. 46, 1-34.
40. Symons, A.L., Leong, K., Zhang, C.Z., Young, W.G., Waters, M.J. and Seymour, G.J. (1994) The distribution of growth hormone receptor associated with tooth development in the rat. In: The Biological Mechanisms of Tooth Eruption, Resorption and Replacement by Implants. Edited by Z. Davidovitch, Harvard Society for The Advancement of Orthodontics, Boston, pp. 305-326.
41. Underwood, L.E. and Van Wyk, J.J. (1992) Normal and aberrant growth. In: Willimas Textbook of Endocrinology, J.D. Wilson and D.W. Foster, eds, Saunders Co., Philadephia, 8th edition, pp. 1079-1138.
42. Werther, G.A., Haynes, K., Barnard, R. and Waters, M.J. (1990) Visual demonstration of growth hormone receptors on human growth plate chondrocytes. J. Clin. Endocrinol. Metab. 70, 1725-1731.
43. Zerwekh, J.E., Marks, S.C. Jr. and McGuire, J.L. (1987) Elevated serum 1,25 dihydroxyvitamin D in osteopetrotic mutations in three species. Bone and Mineral 2, 193-201.
44. Zhang, C.Z., Young, W.G. and Waters, M.J. (1992a) Immunocytochemical localisation of growth hormone receptor in rat maxillary teeth. Arch. Oral. Biol. 37, 77-84.
45. Zhang, C.Z., Young, W.G., Li, H., Clayden, A.M., Garcia-Aragon, J. and Waters, M.J. (1992b) Expression of growth hormone receptor by immunocytochemistry in rat molar root formation and alveolar bone remodelling. Calcif. Tissue Int. 50, 541-546.