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Volumn 74, Issue 5, 1996, Pages 269-274

Ursodeoxycholic acid treatment lowers the serum level of antibodies against pyruvate dehydrogenase and influences their inhibitory capacity for the enzyme complex in patients with primary biliary cirrhosis

Author keywords

Autoantibodies; Colchicine; Primary biliary cirrhosis; Pyruvate dehydrogenase; Ursodeoxycholic acid

Indexed keywords

AUTOANTIBODY; COLCHICINE; IMMUNOGLOBULIN G; PLACEBO; PYRUVATE DEHYDROGENASE; URSODEOXYCHOLIC ACID;

EID: 0029946273     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001090050028     Document Type: Article
Times cited : (13)

References (26)
  • 1
    • 0027510927 scopus 로고
    • New strategies needed for treatment of primary biliary cirrhosis
    • Kaplan MM (1993) New strategies needed for treatment of primary biliary cirrhosis. Gastroenterology 104:651-653
    • (1993) Gastroenterology , vol.104 , pp. 651-653
    • Kaplan, M.M.1
  • 4
    • 0025876404 scopus 로고
    • A multicenter, controlled trial of ursodiol for the treatment of primary biliary cirrhosis
    • Poupon RE, Balkau B, Eschwege E, Poupon R, UDCA-PBC Study Group (1991) A multicenter, controlled trial of ursodiol for the treatment of primary biliary cirrhosis. N Engl J Med 324:1548-1554
    • (1991) N Engl J Med , vol.324 , pp. 1548-1554
    • Poupon, R.E.1    Balkau, B.2    Eschwege, E.3    Poupon, R.4
  • 7
    • 0023875186 scopus 로고
    • Evaluation of colchicine therapy in primary biliary cirrhosis
    • Bodenheimer H, Schaffner F, Pezzullo J (1988) Evaluation of colchicine therapy in primary biliary cirrhosis. Gastroenterology 95:124-129
    • (1988) Gastroenterology , vol.95 , pp. 124-129
    • Bodenheimer, H.1    Schaffner, F.2    Pezzullo, J.3
  • 8
    • 0025098908 scopus 로고
    • Hepatic expression of class I and II major histocompatibility complex molecules in primary biliary cirrhosis: Effect of ursodeoxycholic acid
    • Calmus Y, Gane P, Rouger P, Poupon R (1990) Hepatic expression of class I and II major histocompatibility complex molecules in primary biliary cirrhosis: effect of ursodeoxycholic acid. Hepatology 11:12-15
    • (1990) Hepatology , vol.11 , pp. 12-15
    • Calmus, Y.1    Gane, P.2    Rouger, P.3    Poupon, R.4
  • 9
    • 0023267078 scopus 로고
    • Identification and specificity of a cDNA encoding the 70kd mitochondrial antigen recognized in primary biliary cirrhosis
    • Gershwin ME, Mackay IR, Sturgess A, Coppel RL (1987) Identification and specificity of a cDNA encoding the 70kd mitochondrial antigen recognized in primary biliary cirrhosis. J Immunol 138:3525-3531
    • (1987) J Immunol , vol.138 , pp. 3525-3531
    • Gershwin, M.E.1    Mackay, I.R.2    Sturgess, A.3    Coppel, R.L.4
  • 11
    • 0025376191 scopus 로고
    • Antibodies against mitochondrial dehydrogenase complexes in primary biliary cirrhosis
    • Yoshida T, Bonkovsky H, Ansari A, Danner D (1990) Antibodies against mitochondrial dehydrogenase complexes in primary biliary cirrhosis. Gastroenterology 99:187-194
    • (1990) Gastroenterology , vol.99 , pp. 187-194
    • Yoshida, T.1    Bonkovsky, H.2    Ansari, A.3    Danner, D.4
  • 12
    • 0025794185 scopus 로고
    • Inhibition of the activity of the 2-oxoacid dehydrogenase complexes by sera from patients with primary biliary cirrhosis
    • Begley JP, Barry RE, Denton RM, Stansbie D (1991) Inhibition of the activity of the 2-oxoacid dehydrogenase complexes by sera from patients with primary biliary cirrhosis. Eur J Gastroenterol Hepatol 3:365-369
    • (1991) Eur J Gastroenterol Hepatol , vol.3 , pp. 365-369
    • Begley, J.P.1    Barry, R.E.2    Denton, R.M.3    Stansbie, D.4
  • 13
    • 0028094097 scopus 로고
    • Enzyme-linked immunosorbent assays for the determination of IgG, IgA and IgM autoantibodies to pyruvate dehydrogenase in primary biliary cirrhosis
    • Kisand K, Kisand K, Salupere V, Uibo R (1994) Enzyme-linked immunosorbent assays for the determination of IgG, IgA and IgM autoantibodies to pyruvate dehydrogenase in primary biliary cirrhosis. Int J Clin Lab Res 24:98-101
    • (1994) Int J Clin Lab Res , vol.24 , pp. 98-101
    • Kisand, K.1    Kisand, K.2    Salupere, V.3    Uibo, R.4
  • 14
    • 0000022703 scopus 로고
    • The mammalian 2-oxoacid dehydrogenases: A complex family
    • Yeaman SJ (1986) The mammalian 2-oxoacid dehydrogenases: a complex family. Trends Biochem Sci 11:293-296
    • (1986) Trends Biochem Sci , vol.11 , pp. 293-296
    • Yeaman, S.J.1
  • 16
    • 0015853344 scopus 로고
    • Maturation of the head of bacteriophage T4
    • Laemlli UK, Favre M. Maturation of the head of bacteriophage T4 (1973) J Mol Biol 80:575-599
    • (1973) J Mol Biol , vol.80 , pp. 575-599
    • Laemlli, U.K.1    Favre, M.2
  • 17
    • 0028051744 scopus 로고
    • Enzyme inhibitory autoantibodies to pyruvate dehydrogenase complex in primary biliary cirrhosis: Applications of a semiautomated assay
    • Teoh KL, Rowley MJ, Zafirakis H, Dickson ER, Wiesner RH, Gershwin ME, Mackay IR (1994) Enzyme inhibitory autoantibodies to pyruvate dehydrogenase complex in primary biliary cirrhosis: applications of a semiautomated assay. Hepatology 20:1220-1224
    • (1994) Hepatology , vol.20 , pp. 1220-1224
    • Teoh, K.L.1    Rowley, M.J.2    Zafirakis, H.3    Dickson, E.R.4    Wiesner, R.H.5    Gershwin, M.E.6    Mackay, I.R.7
  • 18
    • 0028213843 scopus 로고
    • Enzyme inhibitory autoantibodies to pyruvate dehydrogenase complex in primary biliary cirrhosis differ for mammalian, yeast and bacterial enzymes: Implications for molecular mimicry
    • Teoh K-L, Mackay IR, Rowley MJ, Fussey SPM (1994) Enzyme inhibitory autoantibodies to pyruvate dehydrogenase complex in primary biliary cirrhosis differ for mammalian, yeast and bacterial enzymes: implications for molecular mimicry. Hepatology 19:1029-1033
    • (1994) Hepatology , vol.19 , pp. 1029-1033
    • Teoh, K.-L.1    Mackay, I.R.2    Rowley, M.J.3    Fussey, S.P.M.4
  • 20
    • 0027241605 scopus 로고
    • Sera from patients with tuberculosis recognize the M2a-epitope (E2-subunit of pyruvate dehydrogenase) specific for primary biliary cirrhosis
    • Klein R, Wiebel M, Engelhart S, Berg PA (1993) Sera from patients with tuberculosis recognize the M2a-epitope (E2-subunit of pyruvate dehydrogenase) specific for primary biliary cirrhosis. Clin Exp Immunol 92:308-316
    • (1993) Clin Exp Immunol , vol.92 , pp. 308-316
    • Klein, R.1    Wiebel, M.2    Engelhart, S.3    Berg, P.A.4
  • 23
    • 0027319044 scopus 로고
    • Molecular mimicry in primary biliary cirrhosis. Evidence for biliary epithelial expression of a molecule cross-reactive with pyruvate dehydrogenase complex-E2
    • Van de Water J, Turchany J, Leung PS, Lake J, Munoz S, Surh CD, Coppel R, Ansari A, Nakanuma Y, Gershwin ME (1993) Molecular mimicry in primary biliary cirrhosis. Evidence for biliary epithelial expression of a molecule cross-reactive with pyruvate dehydrogenase complex-E2. J Clin Invest 91:2653-2664
    • (1993) J Clin Invest , vol.91 , pp. 2653-2664
    • Van De Water, J.1    Turchany, J.2    Leung, P.S.3    Lake, J.4    Munoz, S.5    Surh, C.D.6    Coppel, R.7    Ansari, A.8    Nakanuma, Y.9    Gershwin, M.E.10
  • 24
    • 0026034491 scopus 로고
    • Primary biliary cirrhosis: Paradigma or paradox for autoimmunity
    • Gershwin ME, Mackay IR (1991) Primary biliary cirrhosis: paradigma or paradox for autoimmunity. Gastroenterology 100:822-833
    • (1991) Gastroenterology , vol.100 , pp. 822-833
    • Gershwin, M.E.1    Mackay, I.R.2
  • 26
    • 0026663426 scopus 로고
    • Immunosuppressive properties of chenodeoxycholic and ursodeoxycholic acids in the mouse
    • Calmus Y, Weill B, Ozier Y, Chereau C, Houssin D, Poupon R. (1992) Immunosuppressive properties of chenodeoxycholic and ursodeoxycholic acids in the mouse. Gastroenterology 103:617-621
    • (1992) Gastroenterology , vol.103 , pp. 617-621
    • Calmus, Y.1    Weill, B.2    Ozier, Y.3    Chereau, C.4    Houssin, D.5    Poupon, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.