Risk factors of psychosis: Identifying vulnerable populations premorbidly

Schizophrenia Bulletin

Volumn 22, Issue 2, 1996, Pages 223-240

  Olin, Su Chin Serene ^a   Mednick, Sarnoff A ^a,b  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b Institute for Preventative Medicine   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

AFFECTIVE NEUROSIS; AGGRESSION; FAMILY HISTORY; HUMAN; INSTITUTIONALIZATION; MORBIDITY; PRIORITY JOURNAL; PSYCHOSIS; PSYCHOSOCIAL WITHDRAWAL; REVIEW; RISK ASSESSMENT; RISK FACTOR; SOCIAL INTERACTION;

EID: 0029946144     PISSN: 05867614     EISSN: None     Source Type: Journal    
DOI: 10.1093/schbul/22.2.223     Document Type: Review

References (93)

1. Adams, W.; Kendell, R.E.; Hare, E.H.; and Munk, J.P. Epidemiological evidence that maternal influenza contributes to the aetiology of schizophrenia: An analysis of Scottish, English, and Danish data. British Journal of Psychiatry, 163:522-534, 1993.
2. American Psychiatric Association. DSM-III-R: Diagnostic and Statistical Manual of Mental Disorders. 3rd ed., revised. Washington, DC: The Association, 1987.
3. Asarnow, J.R. Children at risk for schizophrenia: Converging lines of evidence. Schizophrenia Bulletin, 14(4):613-631, 1988.
4. Barr, C.E.; Mednick, S.A.; and Ekstrom, M. "Very Early Parental Separation: A Risk Factor for Schizophrenia and Other Psychiatric Disorders." Submitted for publication a.
5. Barr, C.E.; Mednick, S.A.; Ekstrom, M.; Sorensen, H.; Schulsinger, F.; and Jorgensen, P.M. "Family History of Schizophrenia and Delivery Complications: Evidence From an Interactive Model." Submitted for publication b.
6. Barr, C.E.; Mednick, S.A.; and Munk-Jorgenson, J.P. Exposure to influenza epidemics during gestation and adult schizophrenia: A 40-year study. Archives of General Psychiatry, 47:869-874, 1990.
7. Bebbington, P., and Kuipers, L. The predictive utility of expressed emotion in schizophrenia: An aggregate analysis. Psychological Medicine, 24:707-718, 1994.
8. Burman, B.; Mednick, S.A.; Machon, R.; Parnas, J.; and Schulsinger, F. Perception of family relationships of children at high-risk for schizophrenia. Journal of Abnormal Psychology, 96:364-366, 1987.
9. Cannon, T.D.; Mednick, S.A.; and Pamas, J. Genetic and perinatal determinants of structural brain deficits in schizophrenia. Archives of General Psychiatry, 46:883-889, 1989.
10. Cannon, T.D.; Mednick, S.A.; and Parnas, J. Antecedents of predominantly negative and predominantly positive schizophrenia in a high risk population. Archives of General Psychiatry, 47:622-632, 1990.
11. Chapman, L.J., and Chapman, J.P. The search for symptoms predictive of schizophrenia. Schizophrenia Bulletin, 13(3):497-503, 1987.
12. Chapman, L.J.; Chapman, J.P.; Kwapil, T.R.; Eckblad, M.; and Zinser, M.C. Putatively psychosisprone subjects 10 years later. Journal of Abnormal Psychology, 103:171-183, 1994.
13. Chapman, L.J.; Chapman, J.P.; Numbers, J.S.; Edell, W.S.; Carpenter, B.N.; and Beckfield, D. Impulsive nonconformity as a trait contributing to the prediction of psychotic-like and schizotypal symptoms. Journal of Nervous and Mental Disease, 172:681-691, 1984.
14. Chapman, L.J.; Chapman, J.P.; and Raulin, M.L. Scales for physical and social anhedonia. Journal of Abnormal Psychology, 85:374-382, 1976.
15. Chapman, L.J.; Chapman, J.P.; and Raulin, M.L. Body-image aberration in schizophrenia. Journal of Abnormal Psychology, 87:399-407, 1978.
16. Cornblatt, B.A.; Lenzenweger, M.F.; Dworkin, R.H.; and Erlenmeyer-Kimling, L. Childhood attentional dysfunctions predict social deficits in unaffected adults at risk for schizophrenia. Journal of Psychiatry, 161(Suppl. 18):59-64, 1992.
17. Eckblad, M., and Chapman, L.J. Magical ideation as an indicator of schizotypy. Journal of Consulting and Clinical Psychology, 51:215-225, 1983.
18. Eckblad, M.; Chapman, L.J.; Chapman, J.P.; and Mishlove, M. "The Revised Social Anhedonia Scale." Unpublished manuscript available from L.J. Chapman, Department of Psychology, 1202 West Johnson Street, University of Wisconsin, Madison, WI 53706, 1982.
19. Erlenmeyer-Kimling, L., and Cornblatt, B.A. The New York High-Risk Project: A followup report. Schizophrenia Bulletin, 13(3):451-461, 1987.
20. Erlenmeyer-Kimling, L.; Cornblatt, B.A.; and Golden, R. Early indicators of vulnerability to schizophrenia in children at high genetic risk. In: Guze, S.B.; Earls, F.J.; and Barrett, J.E., eds. Childhood Psychopathology and Development. New York, NY: Raven Press, 1983. pp. 247-263.
21. Erlenmeyer-Kimling, L.; Cornblatt, B.A.; Rock, D.; Roberts, S.; Bell, M.; and West, A. The New York High-Risk Project: Anhedonia, attentional deviance, and psychopathology. Schizophrenia Bulletin, 19(1):141-153, 1993.
22. Erlenmeyer-Kimling, L.; Squires-Wheeler, E.; Adamo, D.H.; Bassett, A.S.; Cornblatt, B.A.; Kestenbaum, C.J.; Rock, D.; Roberts, S.A.; and Gottesman, I.I. The New York High-Risk Project: Psychoses and cluster A personality disorders in offspring of schizophrenic parents at 23 years of follow-up. Archives of General Psychiatry, 52:857-865, 1995.
23. Fish, B. Infant predictors of the longitudinal course of schizophrenic development. Schizophrenia Bulletin, 13(3):395-409, 1987.
24. Fish, B.; Marcus, J.; Hans, S.L.; Auerbach, J.G.; and Perdue, S. Infants at risk for schizophrenia: Sequelae of a genetic neurointegrative defect. Archives of General Psychiatry, 49:221-235, 1992.
25. Fromm-Reichman, F. Psychoanalysis and Psychotherapy: Selected Papers. Chicago, IL: University of Chicago Press, 1959. pp. 161-164.
26. Golden, R.R. A taxometric model for detection of a conjectured latent taxon. Multivariate Behavioral Research, 17:389-416, 1982.
27. Golden, R.R., and Meehl, P.E. Detection of the schizoid taxon with MMPI indicators. Journal of Abnormal Psychology, 88:212-233, 1979.
28. Goldstein, J.M. Gender differences in the course of schizophrenia. American Journal of Psychiatry, 145:684-689, 1988.
29. Goldstein, M.J. The UCLA High-Risk Project. Schizophrenia Bulletin, 13(3):505-514, 1987.
30. Goodman, S.H. Emory University Project on Children of Disturbed Parents. Schizophrenia Bulletin, 13(3):411-423, 1987.
31. Gutkind, D., and Mednick, S.A. "Parental Absence and Schizophrenia in High-Risk Children." In preparation.
32. Hans, S.L.; Marcus, J.; Henson, L.; Auerbach, J.G.; and Mirsky, A.F. Interpersonal behavior of children at risk for schizophrenia. Psychiatry, 55:314-335, 1992.
33. Heston, L.L. Psychiatric disorders in foster home reared children of schizophrenic mothers. British Journal of Psychiatry, 112:819-825, 1966.
34. Hsiao, J.K.; Bartko, J.J.; and Potter, W.Z. Diagnosing diagnoses. Archives of General Psychiatry, 46:664-667, 1989.
35. Janes, C.L.; Weeks, D.G.; and Worland, J. School behavior in adolescent children of parents with mental disorder. Journal of Nervous and Mental Disease, 171:234-240, 1983.
36. John, R.S.; Mednick, S.A.; and Schulsinger, F. Teacher reports as a predictor of schizophrenia and borderline schizophrenia: A Bayesian decision analysis. Journal of Abnormal Psychology, 91:399-413, 1982.
37. Kallmann, F.J. The Genetics of Schizophrenia. New York, NY: Augustin Publisher, 1938.
38. Kety, S.S. Schizophrenic illness in the families of schizophrenic adoptees: Findings from the Danish national sample. Schizophrenia Bulletin, 14(2):217-222, 1988.
39. Kety, S.S., and Ingraham, L.J. Genetic transmission and improved diagnosis of schizophrenia in pedigrees of adoptees. Journal of Psychiatry Research, 26:247-255, 1992.
40. Kety, S.S.; Rosenthal, D.; Wender, P.H.; and Schulsinger, F. Mental illness in the biological and adoptive families of adoptive individuals who have become schizophrenic: A preliminary report based on psychiatric interviews. In: Fieve, R.R.; Rosenthal, D.; and Brill, H., eds. Genetic Research in Psychiatry. Baltimore, MD: Johns Hopkins University Press, 1975. pp. 147-165.
41. Klorman, R.; Strauss, J.S.; and Kokes, R.F. Premorbid adjustment in schizophrenia: Concepts, measures, and implications: III. The relationship of demographic and diagnostic factors to measures of premorbid adjustment in schizophrenia. Schizophrenia Bulletin, 3(2):214-225, 1977.
42. Kohlberg, L.; Ricks, D.; and Snarey, J. Childhood development as a predictor of adaptation in adulthood. Genetic Psychological Monographs, 110:91-172, 1984.
43. Kokes, R.F.; Strauss, J.S.; and Klorman, R. Premorbid adjustment in schizophrenia: Concepts, measures, and implications: II. Measuring premorbid adjustment: The instruments and their development. Schizophrenia Bulletin, 3(2):186-213, 1977.
44. Kunugi, H.; Nanko, S.; Takei, N.; Saito, K.; Hayashi, N.; and Kazamatsuri, H. Schizophrenia following in utero exposure to the 1957 influenza epidemic in Japan. American Journal of Psychiatry, 1152:450-452, 1995.
45. Lafosse, J.M. "Motor Coordination in Adolescence and Its Relationship to Adult Schizophrenia." Unpublished dissertation, University of Southern California, Los Angeles, 1994.
46. Mahler, M.S.; Pine, F.; and Bergman, A. The Psychological Birth of the Child. New York, NY: Basic Books, 1975.
47. Marcus, J.; Hans, S.L.; Auerbach, J.G.; and Auerbach, A.G. Children at risk for schizophrenia: The Jerusalem Infant Development Study: II. Neurobehavioral deficits at school age. Archives of General Psychiatry, 50:797-809, 1993.
48. Marcus, J.; Hans, S.L.; Nagler, S.; Auerbach, J.G.; Mirsky, A.F.; and Aubrey, A. Review of the NIMH Israeli Kibbutz-City Study and the Jerusalem Infant Development Study. Schizophrenia Bulletin, 13(3):425-438, 1987.
49. McGrath, J.J.; Pemberton, M.R.; Welham, J.L.; and Murray, R.M. Schizophrenia and the influenza epidemics of 1954, 1957, and 1959: A Southern hemisphere study. Schizophrenia Research, 14:1-8, 1994.
50. McNeil, T.F. Obstetric complications in schizophrenic parents. Schizophrenia Research, 5:89-101, 1991.
51. McNeil, T.F., and Kaij, L. Swedish High-Risk Study: Sample characteristics at age 6. Schizophrenia Bul-letin, 13(3):373-381, 1987.
52. Mednick, S.A. "Fetal Neural Development and Adult Schizophrenia." Presented at the American College of Neuropsychopharmacology in San Juan, Puerto Rico, December 1994.
53. Mednick, S.A.; Huttunen, M.O.; and Machón, R.A. Prenatal influenza infections and adult schizophrenia. Schizophrenia Bulletin, 20(2):263-267, 1994.
54. Mednick, S.A.; Machón, R.A.; Huttunen, M.O.; and Bonnet, D. Adult schizophrenia following prenatal exposure to an influenza epidemic. Archives of General Psychiatry, 45:189-192, 1988.
55. Mednick, S.A.; Mura, E.; Schulsinger, F.; and Mednick, B. Perinatal conditions and infant development in children with schizophrenic parents. Social Biology, 18(Suppl.):102-113, 1971.
56. Mednick, S.A.; Parnas, J.; and Schulsinger, F. The Copenhagen High-Risk Project, 1962-86. Schizophrenia Bulletin, 13(3):485-495, 1987.
57. Mednick, S.A., and Silverton, L. High-risk studies of the etiology of schizophrenia. In: Tsuang, M.T., and Simpson, J.C., eds. Handbook of Schizophrenia, Nosology, Epidemiology, and Genetics of Schizophrenia. Vol. 3. New York, NY: Elsevier Science Publishers, 1988. pp. 543-562.
58. Meehl, P.E. Schizotaxia, schizotypy, schizophrenia. American Psychologists, 17:827-837, 1962.
59. Meehl, P.E. MAXCOV-HITMAX: A taxonomic search method for loose genetic syndromes. In: Meehl, P.E., ed. Psychodiagnosis: Selected Papers. Minneapolis, MN: University of Minnesota Press, 1973. pp. 200-224.
60. Meehl, P.E. Schizotaxia revisited. Archives of General Psychiatry, 46:935-944, 1989.
61. Meehl, P.E. Toward an integrated theory of schizotaxia, schizotypy, and schizophrenia. Journal of Personality Disorders, 4:1-99, 1990.
62. Mossman, D., and Somoza, E. Maximizing diagnostic information using the dexamethasone suppression test: An approach to criterion selection using receiver operating characteristic analysis. Archives of General Psychiatry, 46:653-660, 1989.
63. Murray, R.M.; Jones, P.B.; O'Callaghan, E.; Takei, N.; and Sham, P. Genes, viruses, and neurodevelopmental schizophrenia. Journal of Psychiatric Research, 26:225-235, 1992.
64. Offord, D.R., and Cross, L.A. Behavioral antecedents of adult schizophrenia. Archives of General Psychiatry, 21:267-283, 1969.
65. Olin, S.S.; John, R.S.; and Mednick, S.A. Assessing the predictive value of teacher reports in a high risk sample for schizophrenia: An ROC analysis. Schizophrenia Research, 16:53-66, 1995.
66. O'Neal, P., and Robins, L.N. Childhood patterns predictive of adult schizophrenia: A 30-year follow-up study. American Journal of Psychiatry, 115:385-391, 1958.
67. Parnas, J.; Cannon, T.D.; Jacobsen, B.; Schulsinger, H.; Schulsinger, F.; and Mednick, S. Lifetime DSM-III-R diagnostic outcomes in the offsprings of schizophrenic mothers. Archives of General Psychiatry, 50:707-714, 1993.
68. Ragin, N.; Schachter, J.; Elmer, E.; Preisma, R.; Bowes, A.E.; and Harway, V. Infants and children at risk for schizophrenia. Journal of the American Academy of Child Psychiatry, 14:150-177, 1975.
69. Ricks, D.F., and Nameche, G. Symbiosis, sacrifice, and schizophrenia. Mental Hygiene, 50:541-551, 1966.
70. Robbins, M. Psychoanalytic and biological approaches to mental illness: Schizophrenia. Journal of the American Psychoanalytic Association, 40:425-454, 1992.
71. Rosenthal, D.; Wender, P.H.; Kety, S.S.; Weiner, J.; and Schulsinger, F. The adopted away offspring of schizophrenics. American Journal of Psychiatry, 128:307-311, 1971.
72. Rosvold, H.E.; Mirsky, A.F.; Sarason, I.; Bransome, E.D., Jr.; and Beck, L.H. A continuous performance test of brain damage. Journal of Consulting Psychology, 20:343-350, 1956.
73. Rund, B.R. Communication deviances in parental schizophrenics. Family Process, 25:133-147, 1986.
74. Rund, B.R. The relationship between psychosocial and cognitive functioning in schizophrenic patients and expressed emotion and communication deviance in their parents. Acta Psychiatrica Scandinavica, 90:133-140, 1994.
75. Rutter, M. Protective factors in children's responses to stress and disadvantage. In: Kent, M.W., and Rolf, J.E., eds. Primary Prevention of Psychopathology: Social Competence in Children. Hanover, NH: University Press of New England, 1979. pp. 49-74.
76. Sameroff, A.; Seifer, R.; Zax, M.; and Barocas, R. Early indicators of developmental risk: Rochester Longitudinal Study. Schizophrenia Bulletin, 13(3):383-394, 1987.
77. Schum, D.A., and Pfeiffer, P.E. A likelihood ratio approach to classification problems using discrete data. Organization of Behavior and Human Performance, 19:207-225, 1977.
78. Schwartzman, A.E.; Ledingham, J.E.; and Serbin, L.A. Identification of children at risk for adult schizophrenia: A longitudinal study. International Review of Applied Psychology, 34:363-380, 1985.
79. Stott, D.H. A general test for motor impairment for children. Developmental Medicine and Child Neurology, 8:523-531, 1966.
80. Swets, J.A., and Pickett, R.M. Evaluation of Diagnostic Systems: Methods From Signal Detection Theory. New York, NY: Academic Press, 1982.
81. Talovic, S.A. "High-Risk for Schizophrenia: Father's Contribution to Child Outcome." Unpublished doctoral dissertation, University of Southern California, Los Angeles, 1984.
82. Tienari, P.; Sorri, A.; Lahti, I.; Naarala, M.; Wahlberg K.-E.; Moring, J.; Pohjola, J.; and Wynne, L.C. Genetic and psychosocial factors in schizophrenia: The Finnish Adoptive Family Study. Schizophrenia Bulletin, 13(3):477-484, 1987.
83. Tienari, P.; Wynne, L.C.; Moring, J.; Lahti, I.; Naarala, M.; Sorri, A.; Wahlberg, K.E.; Saarento, O.; Seitamaa, M.; Kaleva, M.; and Laksy, K. The Finnish Adoptive Family Study of Schizophrenia: Implications for family research. British Journal of Psychiatry, 23(Suppl.):20-26, 1994.
84. Tyrka, A.R.; Cannon, T.D.; Haslam, N.; Mednick, S.A.; Schulsinger, F.; Schulsinger, H.; and Parnas, J. The latent structure of schizotypy: I. Premorbid indicators of a taxon of individuals at risk for schizophrenia-spectrum disorders. Journal of Abnormal Psychology, 104:173-183, 1995.
85. Walker, E.F.; Cudeck, R.; Mednick, S.A.; and Schulsinger, F. Effects of parental absence and institutionalization on the development of clinical symptoms in high-risk children. Acta Psychiatrica Scandinavica, 63:95-109, 1981.
86. Walker, E.F., and Lewine, R.J. Prediction of adult-onset schizophrenia from childhood home movies of patients. American Journal of Psychiatry, 147:1052-1056, 1990.
87. Watt, N.F. Longitudinal changes in the social behavior of children hospitalized for schizophrenia as adults. Journal of Nervous and Mental Disorders. 155:42-54, 1972.
88. Watt, N.F. Patterns of childhood social development in adult schizophrenics. Archives of General Psychiatry, 35:160-165, 1978.
89. Watt, N.F.; Grubb, T.W.; and Erlenmeyer-Kimling, L. Social, emotional, and intellectual behavior at school among children at high risk for schizophrenia. Journal of Consulting and Clinical Psychology, 50:171-181, 1982.
90. Watt, N.F., and Lubensky, A.W. Childhood roots of schizophrenia. Journal of Consulting and Clinical Psychology, 44:363-375, 1976.
91. Wechsler, D. The Wechsler Intelligence Scale for Children. New York, NY: The Psychological Corporation, 1949.
92. Wrede, G.; Mednick, S.A.; Huttunen, M.O.; and Nilsson, G.G. Pregnancy and delivery complications in the births of an unselected series of Finnish children with schizophrenic mothers. In: Watt, N.F.; Anthony, J.E.; Wynne, L.C; and Rolf, J.E., eds. Children at High Risk for Schizophrenia: A Longitudinal Perspective. New York, NY: Cambridge University Press, 1984. pp. 515-525.
93. Ziegler, E.; Levine, J.; and Ziegler, B. Premorbid social competence and paranoid-nonparanoid status in female schizophrenic patients. Journal of Nervous and Mental Disease, 164:333-339, 1977.