Rabbit lens and retina phosphorylate glucose through a glucokinase-like enzyme: Study in normal and spontaneously hyperglycemic animals

Journal of Diabetes and its Complications

Volumn 10, Issue 2, 1996, Pages 68-77

  Iannello, Silvia ^a   Campione, Rosa ^a   Volpicelli, Giovanni ^a   Belfiore, Francesco ^a,b  

^a UNIVERSITY OF CATANIA   (Italy)

^b GARIBALDI HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME; GLUCOKINASE; GLUCOSE; GLUCOSE 6 PHOSPHATE; HEXOKINASE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE UTILIZATION; HOMOGENATE; HYPERGLYCEMIA; LENS; NONHUMAN; OPTICAL DENSITY; PH; PHOSPHORYLATION; PRIORITY JOURNAL; RABBIT; RETINA; SUPERNATANT;

EID: 0029945972     PISSN: 10568727     EISSN: None     Source Type: Journal    
DOI: 10.1016/1056-8727(94)00080-8     Document Type: Article

References (45)

1. Engerman R, Bloodworth JMB Jr, Nelson S: Relationship of microvascular disease in diabetes and metabolic control. Diabetes 26:760-769, 1977.
2. Raskin P: Diabetic regulation and its relationship to microangiopathy. Metabolism 27:235-252, 1978.
3. Hanssen KF, Dahl-Jorgensen K, Lauritzen T, Feldt-Rasmussen B, Briuchmann-Hansen O, Deckert T: Diabetic control and microvascular complications: the near-nor-moglycaemia experience. Diabetologia 26:677-684, 1986.
4. Engerman, RL, Kern TS: Hyperglycemia as a cause of diabetic retinopathy. Metabolism 35(suppl 1):20-23, 1986.
5. Winegrad, AI: Does a common mechanism induce the diverse complications of diabetes? Banting Lecture 1986. Diabetes 36:396-406, 1987.
6. Marano CW, Matschinsky FM: Biochemical manifestations of diabetes mellitus in microscopic layers of the cornea and retina. Diabetes Metab Rev 5:1-15, 1989.
7. Belfiore F, Iannello S, Campione R, Volpicelli G: Capillaries phosphorylate glucose in a concentration-dependent manner through a glucokinase-like enzyme: A study in the eel. Biochem Med Metab Biol 43:226-233, 1990.
8. Belfiore F, Iannello S, Campione R, Volpicelli G: Glucose metabolism in capillaries, in Shafrir E (ed), Frontiers in Diabetes Research: Lessons from Animal Diabetes III, Smith-Gordon, London, 1990, pp. 435-438.
9. Belfiore F, Iannello S, Campione R, Bombaci M, Gulisano U: Selected aspects of capillary morphology and metabolism in diabetes. Front Diabetes 9:57-63, 1990.
10. Belfiore F, Iannello S, Campione R, Volpicelli G, Gulisano U: A glucokinase-like enzyme carries out glucose phosphorylation in capillaries of normal and spontaneously hyperglycemic rabbits. Biochem Med Metab Biol 49:326-337, 1993.
11. Iannello S, Belfiore F, Campione R, Volpicelli G, Gulisano U: Rabbit optic nerve phosphorylates glucose in a concentration-dependent manner through a glucokinase-like enzyme [Abstract] in "Controversies in Etiology and Treatment of Diabetic Neuropathy," 14th IDF Congress Satellite Symposium, New York, June 29-July 2, 1991.
12. Iannello S, Campione R, Volpicelli G, Belfiore F: Rabbit optic nerve phosphorylates glucose through a glucokinase-like enzyme. Studies in normal and spontaneously hyperglycemic animals. Biochem Med Metab Biol 53:122-129, 1994.
13. Belfiore R: Enzyme Regulation and Metabolic Diseases. Karger, Basel, 1980, pp. 194-198 and pp. 477-478.
14. Vinuela E, Salas M, Sols A: Glucokinase and hexokinase in liver in relation to glycogen synthesis. J Biol Chem 238:PC1175-1177, 1963.
15. Walker DG: On the presence of two soluble glucose phosphorylating enzymes in adult liver and the development of one of these after birth. Biochem Biophys Acta 77:209-226, 1963.
16. Grossbard L, Schimke RT: Multiple hexokinases of rat tissues. Purification and comparison of soluble forms. J Biol Chem 241:3546-3560, 1966.
17. Bedoya FJ, Wilson JM, Ghosh AK, Finegold D, Matschinsky FM: The glucokinase glucose sensor in human pancreatic islet tissue. Diabetes 35:61-67, 1986.
18. Moore RO, Chandler AM, Tetterhorst N: Glucose-ATP transferases in adipose tissue of fasted and refed rats. Biochem Biophys Res Commun 17:527-531, 1964.
19. Gonzalez AM, Sochor M, Hothersall JS, McLean P: Effect of experimental diabetes on the activity of hexokinase in rat lens; an example of glucose overutilization in diabetes. Biochem Biophys Res Commun 84:858-864, 1978.
20. Okuda J, Miwa I, Ueda M, Taketa K: D-Glucose anomeric preference of hexokinases in higher animals. J Biochem (Tokyo) 84:993-995, 1978.
21. Sochor M, Baquer NZ, Hothersall JS, McLean P: Effect of experimental diabetes on the activity of hexokinase isoenzymes in tissues of the rat. Biochem Int 22:467-474, 1990.
22. Murphy ED, Anderson JW: Tissue glycolytic and gluconeogenic enzyme activities in mildly and moderately diabetic rats: Influence of tolbutamide administration. Endocrinology 94:27-34, 1974.
23. Parry MJ, Walker DG: Purification and properties of adenosine 5′-triphosphate-D-glucose 6 phosphotransferase from rat liver. Biochem J 99:266-274, 1966.
24. Davidson AL, Arion WJ: Factors underlying significant underestimation of glucokinase activity in crude liver extracts: physiological implications of higher cellular activity. Arch Biochem Biophys 253:156-167, 1987.
25. Vandercammen A, Van Schaftingen E: Species and tissue distribution of the regulatory protein of glucokinase. Biochem J 294:551-556, 1993.
26. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ: Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-275, 1951.
27. Allen MB, Walker DG: Kinetic characterization of N-acetyl-D-glucosamine kinase from rat liver and kidney. Biochem J 185:577-582, 1980.
28. Allen MB, Brockelbank JL, Walker DG: Apparent "glucokinase" activity in non-hepatic tissues due to N-acetyl-D-glucosamine kinase. Biochim Biophys Acta 614: 357-366, 1980.
29. Vera ML, Cardenas ML, Niemeyer H: Kinetic, chromatographic and electrophoretic studies on glucose phosphorylating enzymes of rat intestinal mucosa. Archiv Biochem Biophys. 229:237-245, 1984.
30. King GL, Hachiya HL, Ching Fai K, Tian-Shing L: Characterization of the effects of insulin, IGF and hyperglycemia on the metabolism and functions of vascular endothelial cells. Front Diabetes 9:86-96, 1990.
31. Giroix MH, Sener A, Pipeleers DG, Malaisse WJ: Hexose metabolism in pancreatic islets. Inhibition of hexokinase, Biochem J 223:447-453, 1984.
32. MacGregor LC, Matschinsky FM: Experimental diabetes mellitus impairs the function of the retinal pigmented epithelium. Metabolism 35 (suppl 1):28-34, 1986.
33. Vionnet N, Stoffel M, Takeda J, Yasuda K, Bell GI, Zouali H, Lesage S, Velho G, Iris F, Passa P: Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitus. Nature 356: 721-722, 1992.
34. Gabbay KH: Hyperglycemia, polyol metabolism and complications of diabetes mellitus. Annu Rev Med 26: 521-536, 1975.
35. Kador PF, Akag R, Kinoshita JH: The effect of aldose reductase and its inhibition on sugar cataract formation. Metabolism 35(suppl 1): 15-19, 1986.
36. Yeh-L-A, Rafford CE, Beyer TA, Hutson NJ: Effects of the aldose reductase inhibitor Sorbinil on the isolated cultured rat lenses. Metabolism 35 (suppl 1):4-9, 1986.
37. Chiou SH, Chylack LT Jr, Bunn FH, Kinoshita JH: Role of nonenzymatic glycosylation in experimental cataract formation. Biochem Biophy Res Commun 95:895-901, 1980.
38. Brownlee M, Vlassara H, Cerami A: Nonenzymatic glycosylation and the pathogenesis of diabetic complications. Ann Int Med 101:527-537, 1984.
39. Belfiore F, Iannello S, Rabuazzo AM, Campione R: Increased hexokinase/glucose-6-phosphatase ratio (HK/ G6Pase) in the diabetic kidney as index of glucose overutilization. Clin Physiol Biochem 7:223-228, 1989.
40. Belfiore F, Rabuazzo AM, Iannello S, Campione R, Vasta D: Anabolic response of some tissues to diabetes. Biochem Med Metab Biol 35:149-155, 1986.
41. Belfiore F, Iannello S, Campione R, Volpicelli G, Caraffa F: Metabolic effects of hyperglycemia in various tissues. Front Diabetes 10:124-133, 1990.
42. Lowry OH, Roberts NK, Schulz DW: Quantitative histochemistry of retina. II. Enzymes of glucose metabolism. J Biol Chem 236:2813-2820, 1961.
43. Matschinsky FM: Quantitative histochemistry of nicotinamide adenine nucleotides in retina of monkey and rabbit. J Neurochem 15:643-657, 1968.
44. Varma SD, Schocket SS, Richards RD: Implications of aldose reductase in cataracts in human diabetes. Invest Ophthalmol Vis Sci 18:237-241, 1979.
45. Cheng HM, Gonzalez RG: The effect of high glucose and oxidative stress on lens metabolism, aldose reductase, and senile cataractogenesis. Metabolism 35 (suppl 1):10-14, 1986.