Strained cyclic cumulene intermediates in Diels-Alder cycloadditions of enynes and diynes

Journal of the American Chemical Society

Volumn 118, Issue 17, 1996, Pages 4218-4219

  Burrell, Richard C ^a   Daoust, Kimberly J ^a   Bradley, Alexander Z ^a   DiRico, Kenneth J ^a   Johnson, Richard P ^a  

^a University of New Hampshire   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INDENE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0029945893     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9601144     Document Type: Article

References (28)

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4. For early studies on enyne cycloadditions, see: (a) Norton. J. A. Chem. Rev. 1942, 31, 319. (b) Kloetzel. M. C. Org. React. 1948, 4, 1. (c) Butz. L. W.; Gaddis, A. M.; Butz, E. W. J.; Davis, R. E. J. Org. Chem. 1940, 5, 379
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16. f = 37.5 kcal/mol.
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21. (a) Characterization data for new compounds are included in the supporting information.
22. (b) Percentages shown in Scheme 1 are from GLC analysis, corrected for unreacted starting material. Conversions were typically 50-80%.
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