Carbon-carbon bond synthesis: The impact of rDNA technology on the production and use of E. coli transketolase

Annals of the New York Academy of Sciences

Volumn 782, Issue , 1996, Pages 513-525

  Lilly, M D ^a   Chauhan, R ^a   French, C ^a   Gyamerah, M ^b   Hobbs, G R ^a   Humphrey, A ^b   Isupov, M ^b   Littlechild, J A ^b   Mitra, R K ^a   Morris, K G ^b   Rupprecht, M ^b   Turner, N J ^b   Ward, J M ^a   Willetts, A J ^b   Woodley, J M ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF EXETER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE; CARBON; CARBON DIOXIDE; GLYCEROL; RECOMBINANT DNA; TRANSKETOLASE;

BACTERIAL GROWTH; BIOTRANSFORMATION; CHEMICAL BOND; CONFERENCE PAPER; ENZYME IMMOBILIZATION; ENZYME ISOLATION; ENZYME PURIFICATION; ENZYME SYNTHESIS; ESCHERICHIA COLI; EXPRESSION VECTOR; MOLECULAR CLONING; NONHUMAN; ORGANIC CHEMISTRY; PROMOTER REGION; PROTEIN MODIFICATION; PROTEIN STRUCTURE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0029945836     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1996.tb40589.x     Document Type: Conference Paper

References (19)

1. VAN DER WERF, M. J., W. J. J. VAN DEN TWEEL, J. KAMPHUIS, S. HARTMANS & J. A. M. DE BONT. 1994. The potential of lyases for the industrial production of optically active compounds. TibTech. 12: 95-103.
2. KRAGL, U., P. APPEL, D. GYGAX, O. GHISALBA & C. WANDREY. 1992. Aldolases for use in carbohydrate synthesis: Enzymatic reaction engineering as a tool for process optimization. In Biochemical Engineering for 2001. Proceedings of Asia-Pacific Biochemical Engineering Conference 1992. S. Furusaki, I. Endo & R. Matsuno, Eds.: 84-87. Springer-Verlag. Tokyo.
3. HOBBS, G. R., M. D. LILLY, N. J. TURNER, J. M. WARD, A. J. WILLETTS & J. M. WOODLEY. 1993. Enzyme catalysed carbon-carbon bond formation: Use of transketolase from Escherichia coli. J. Chem. Soc. Perkin Trans, 1: 165-166.
4. HOBBS, G. R., M. D. LILLY, N. J. TURNER, J. M. WARD & J. M. WOODLEY. 1994. Development of transketolase as a catalyst for carbon-carbon bond formation. In Proc. 6th Europ. Congr. Biotechnol. L. Alberghina, L. Frontali & P. Sensi, Eds.: 463-466. Elsevier. Amsterdam.
5. MYLES, D. C., P. J. ANDRULIS & G. M. WHITESIDES. 1991. A transketolase-based synthesis of (+)-exo-brevicomin. Tetrahedron Lett. 32: 4835-4838.
6. REISENBERG, D., V. SCHULZ, W. A. KNORRE, H. D. POHL, D. KORZ, E. A. SANDERS, A. ROSS & W. D. DECKWER. 1991. High cell density cultivation of Escherichia coli at controlled specific growth rate. J. Biotechnol. 20: 17-28.
7. DRATHS, K. M. & J. W. FROST. 1990. Synthesis using plasmid-based biocatalysis: Plasmid assembly and 3-deoxy-D-arabino-heptulosonate production. J. Am. Chem. Soc. 112: 1657-1659.
8. FRENCH, C. & J. M. WARD. 1995. Improved production and stability of E. coli recombinants expressing transketolase for large-scale biotransformations. Biotechnol. Lett. 17: 247-252.
9. HOBBS, G. R. 1994. Ph.D. thesis, University of London, London, United Kingdom.
10. HOBBS, G. R., R. K. MITRA, R. SHAUHAN, J. M. WOODLEY & M. D. LILLY. Enzyme-catalysed carbon-carbon bond formation: Large-scale production of Escherichia coli transketolase. J. Biotechnol. In press.
11. HELLMUTH, K., D. J. KORZ, E. A. SANDERS & W.-D. DECKWER. 1994. Effect of growth rate on stability and gene expression of recombinant plasmids during continuous and high cell density cultivation of Escherichia coli TG1. J. Biotechnol. 32: 289-298.
12. FREEMAN, A., J. M. WOODLEY & M. D. LILLY. 1993. In situ product removal as a tool for bioprocessing. Bio/technology 11: 1007-1012.
13. FRENCH, C. & J. M. WARD. 1994. Enzyme immobilization by genetically attached poly-lysine affinity tails. In Proceedings of 3rd International Symposium. Perspectives on Protein Engineering and Complementary Technologies.
14. WOODLEY, J. M. & M. D. LILLY. 1994. Biotransformation reactor selection and operation. In Applied Biocatalysis. J. M. S. Cabrai, D. Best, L. Boross & J. Tramper, Eds.: 371-394.
15. SPRENGER, G. A. 1993. Nucleotide sequence of the Escherichia coli K-12 transketolase. Biochim. Biophys. Acta 1216: 307-310.
16. LINDQVIST, Y., G. SCHNEIDER, U. ERMLER & M. SUNDSTROM. 1992. Three-dimensional structure of transketolase, a thiamine diphosphate dependent enzyme, at 2.5-Å resolution. EMBO J. 11: 2373-2379.
17. NIKKOLA, M., Y. LINDQVIST & G. SCHNEIDER. 1994. Refined structure of transketolase from Saccharomyces cerevisiae at 2.0-Å resolution. J. Mol. Biol. 238: 387-404.
18. LITTLECHILD, J. A., N. J. TURNER, G. R. HOBBS, M. D. LILLY, A. RAWAS & H. C. WATSON. Crystallisation and preliminary X-ray crystallographic data with Escherichia coli transketolase. J. Mol. Biol. Submitted for publication.
19. KRAULIS, P. J. 1991. The MOLSCRIPT - a program to produce both detailed and schematic plots of protein structures. J. Appl. Crystallogr. 24: 946-950.