Molecular structure, conformational analysis, and structure-activity studies of dendrotoxin and its homologues using molecular mechanics and molecular dynamics techniques

Journal of Medicinal Chemistry

Volumn 39, Issue 11, 1996, Pages 2141-2155

  Swaminathan, Panchanadam ^a,e   Hariharan, Meena ^b,f   Murali, Ramachandran ^c   Singh, Chandra U ^d  

^a PFIZER INC   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d A M Technologies Inc   (United States)

^e University of Minnesota ^*  (United States)

^f UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APROTININ; DENDROTOXIN; POTASSIUM CHANNEL;

AMINO ACID SEQUENCE; ARTICLE; CRYSTAL STRUCTURE; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NONHUMAN; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; SEQUENCE HOMOLOGY; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; APROTININ; BUNGAROTOXINS; CATTLE; CYSTEINE; ELAPID VENOMS; HYDROGEN BONDING; MODELS, MOLECULAR; MODELS, STRUCTURAL; MOLECULAR SEQUENCE DATA; NEUROTOXINS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPSIN;

EID: 0029945158     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm950579p     Document Type: Article

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