Role of CRH in the effects of 5-HT-receptor agonists on food intake and metabolic rate

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 271, Issue 5 40-5, 1996, Pages

  Bovetto, Sylvie ^a   Rouillard, Claude ^a   Richard, Denis ^a,b  

^a LAVAL UNIVERSITY   (Canada)

^b UNIVERSITÉ LAVAL   (Canada)

Author keywords

( ) 1 (2,5 dimethoxy 4 iodophenyl) 2 aminopropane hydrochloride; ( ) 8 hydroxy 2 (di n dipropylamino)tetralin hydrobromide; c Fos protein; corticosterone; RU 24969; serotonin

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 4 IODO 2,5 DIMETHOXYAMPHETAMINE; 5 METHOXY 3 (1,2,3,6 TETRAHYDRO 4 PYRIDYL) 1H INDOLE; CORTICOSTERONE; SEROTONIN 1A RECEPTOR; SEROTONIN 1B RECEPTOR; SEROTONIN 2A RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; BASAL METABOLIC RATE; CALORIC INTAKE; ENERGY EXPENDITURE; FOOD INTAKE; HORMONAL REGULATION; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; SATIETY;

EID: 0029944934     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.1996.271.5.r1231     Document Type: Article

References (46)

1. Antoni, F. A. Hypothalamic control of adrenocorticotropin secretion: advances since the discovery of 41-residue corticotropin-releasing factor. Endocrine Rev. 7: 351-378, 1986.
2. Aulakh, C. S., J. L. Hill, H. T. Yoney, and D. L. Murphy. Evidence for involvement of 5-HT1C and 5-HT2 receptors in the food intake suppressant effects of 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI). Psychopharmacology 109: 444-448, 1992.
3. Aulakh, C. S., P. Mazzola-Pomietto, B. Hullihan-Giblin, and D. L. Murphy. Lack of cross-tolerance for hypophagia induced by DOI versus m-CPP suggests separate mediation by 5-HT2 and 5-HT1C receptors, respectively. Soc. Neurosci. Abstr. 19: 1381, 1993.
4. Aulakh, C. S., P. Mazzola-Pomietto, K. M. Wozniak, J. L. Hill, and D. Murphy. Evidence that 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane-induced hypophagia and hyperthermia in rats is mediated by serotonin-2A receptors. J. Pharmacol. Exp. Ther. 270: 127-132, 1994.
5. Bendotti, C., and R. Samanin. The putative role of 5-HT1A and 5-HT1B receptors in the control of feeding in rats. Life Sci. 41: 635-642, 1987.
6. Bill, D. J., M. Knight, E. A. Forster, and A. Fletcher. Direct evidence for an important species difference in the mechanism of 8-OH-DPAT-induced hypothermia. Br. J. Pharmacol. 103: 1857-1864, 1991.
7. Blundell, J. E. Serotonin and the biology of feeding. Am. J. Clin. Nutr. 55: S155-S159, 1992.
8. Bonaz, B., R. Degiorgio, and Y. Tache. Peripheral bombesin induces c-fos protein in the rat brain. Brain Res. 600: 353-357, 1993.
9. Bovetto, S., and D. Richard. Functional assessment of the 5-HT 1A-, 1B-, 2A/2C-, and 3-receptor subtypes on food intake and metabolic rate in rats. Am. J. Physiol. 268 (Regulatory Integrative Comp. Physiol. 37): R14-R20, 1995.
10. Chan, R. K. W., E. R. Brown, A. Ericsson, K. J. Kovacs, and P. E. Sawchenko. A comparison of two immediate-early genes, c-fos and NGFI-B, as markers for functional activation in stress-related neuroendocrine circuitry. J. Neurosci. 13: 5126-3138, 1993.
11. Curran, T., and J. I. Morgan. Fos: an immediate-early transcription factor in neurons. J Neurobiol. 26: 403-412, 1995.
12. Curzon, G. Serotonin and appetite. Ann. NY Acad. Sci. 600: 521-531, 1990.
13. (9-41) prevents the anorectic effect of 17-b-estradiol. Brain Res. Bull. 32: 689-692, 1993.
14. Ding, J. M., W. C. Carver, L. Terracio, and J. Buggy. Proto-oncogene c-fos and the regulation of vasopressin gene expression during dehydration. Mol. Brain Res. 21: 247-255, 1994.
15. Fuller, R. W. Serotonin receptors and neuroendocrine responses. Neuropsychopharmacology 3: 495-502, 1990.
16. Hoffman, G. E., M. S. Smith, and J. G. Verbalis. c-Fos and related immediate early gene products as markers of activity in neuroendocrine systems. Front. Neuroendocrinol. 14: 173-213, 1993.
17. Hutson, P. H., C. T. Dourish, and G. Curzon. Evidence that hyperphagic response to 8-OH-DPAT is mediated by 5-HT1A receptors. Eur. J. Pharmacol. 150: 361-367, 1988.
18. Kennett, G. A., C. T. Dourish, and G. Curzon. 5-HT1B agonists induce anorexia at a postsynaptic site. Eur. J. Pharmacol. 141: 429-435, 1987.
19. 1A presynaptic, but not postsynaptic receptor-mediated responses: relationship to antidepressant-like action. Eur. J. Pharmacol. 138: 53-60, 1987.
20. Kononen, J., J. Honkaniemi, H. Alho, J. Koistinaho, M. Iadarola, and M. Peltohuikko. Fos-like immunoreactivity in the rat hypothalamic-pituitary axis after immobilization stress. Endocrinology 130: 3041-3047, 1992.
21. Krahn, D. D., B. A. Gosnell, A. S. Levine, and J. E. Morley. Behavioral effects of corticotropin-releasing factor: localization and characterization of central effects. Brain Res. 443: 63-69, 1988.
22. Lafarga, M., F. J. Martinezguijarro, M. T. Berciano, J. M. Blascoibanez, M. A. Andres, B. Mellstrom, C. Lopezgarcia, and J. R. Naranjo. Nuclear fos domains in transcriptionally activated supraoptic nucleus neurons. Neuroscience 57: 353-364, 1993.
23. LeFeuvre, R. A., L. Aisenthal, and N. J. Rothwell. Involvement of corticotrophin-releasing factor (CRF) in the thermogenic and anorexic actions of serotonin (5-HT) and related compounds. Brain Res. 555: 245-250, 1991.
24. LeFeuvre, R. A., N. J. Rothwell, and M. J. Stock. Activation of brown fat thermogenesis in response to central injection of corticotropin releasing hormone in the rat. Neuropharmacology 26: 1217-1221, 1987.
25. Mezey, E., and M. Palkovits. CRF-containing neurons in the hypothalamic paraventricular nucleus - regulation, especially by catecholamines. Front. Neuroendocrinol. 12: 23-37, 1991.
26. Morgan, J. I., and T. Curran. Stimulus-transcription coupling in the nervous system: involvement of the inducible protooncogenes fos and jun. Annu. Rev. Neurosci. 14: 421-451, 1991.
27. Murphy, B. E. P. Some studies of the protein-binding of steroids and their application to the routine micro and ultramicro measurement of various steroids in body fluids by competitive protein-binding radioassays. J. Clin. Endocrinol. Metab. 27: 973-980, 1967.
28. Murphy, D. L., P. Mazzola-Pomietto, K. M. Wozniak, N. A. Garrick, J. L. Hill, and C. S. Aulakh. Evidence that DOI-induced hyperthermia in rats is mediated by 5-HT2 receptors. Soc. Neurosci. Abstr. 19: 1380, 1993.
29. Olson, B. R., M. Freilino, G. E. Hoffman, E. M. Stricker, A. F. Sved, and J. G. Verbalis. c-fos Expression in rat brain and brainstem nuclei in response to treatments that alter food intake and gastric motility. Mol. Cell. Neurosci. 4: 93-106, 1993.
30. Olson, B. R., G. E. Hoffman, A. F. Sved, E. M. Stricker, and J. G. Verbalis. Cholecystokinin induces c-fos expression in hypothalamic oxytocinergic neurons projecting to the dorsal vagal complex. Brain Res. 569: 238-248, 1992.
31. Pan, L. H., and F. Gilbert. Identification of different mechanisms of action for increases of food intake and plasma ACTH concentration following 5-HT(1a) receptor subtype activation in rat brain. Psychoneuroendocrinology 18: 123-130, 1993.
32. Paxinos, G. and C. Watson. The Rat Brain in Stereotaxic Coordinates. San Diego, CA: Academic, 1986.
33. Racotta, I. S., J. LeBlanc, and D. Richard. The effect of caffeine on food intake in rats: involvement of corticotropin-releasing factor and the sympatho-adrenal system. Pharmacol. Biochem. Behav. 48: 887-892, 1994.
34. Richard, D. Involvement of corticotropin-releasing factor in the control of food intake and energy expenditure. Ann. NY Acad. Sci. 697: 155-172, 1993.
35. Richard, D., P. Boily, M. C. Dufresne, and M. Lecompte. Energy balance and facultative diet-induced thermogenesis in mice fed a high-fat diet. Can. J. Physiol. Pharmacol. 66: 1297-1302, 1988.
36. Richard, D., S. Rivest, and C. Rivier. The 5-hydroxytryptamine agonist fenfluramine increases Fos-like immunoreactivity in the brain. Brain Res. 594: 131-137, 1992.
37. Ritter, S., and T. T. Dinh. 2-Mercaptoacetate and 2-deoxy-D-glucose induce Fos-like immunoreactivity in rat brain. Brain Res. 641: 111-120, 1994.
38. Rivest, S., and C. Rivier. The role of corticotropin-releasing factor and interleukin-1 in the regulation of neurons controlling reproductive functions. Endocrine Rev. 16: 177-199, 1995.
39. Rivest, S., G. Torres, and C. Rivier. Differential effects of central and peripheral injection of interleukin-1b on brain c-fos expression and neuroendocrine functions. Brain Res. 587: 13-23, 1992.
40. Roberts, M. M., A. G. Robinson, M. D. Fitzsimmons, F. Grant, W. S. Lee, and G. E. Hoffman. c-fos Expression in vasopressin and oxytocin neurons reveals functional heterogeneity within magnocellular neurons. Neuroendocrinology 57: 388-400, 1993.
41. Rothwell, N. J. Central effects of CRF on metabolism and energy balance. Neurosci. Biobehav. Rev. 14: 263-271, 1990.
42. Rothwell, N. J., A. Hardwick, R. A. LeFeuvre, S. R. Crosby, and A. White. Central actions of CRF on thermogenesis are mediated by pro-opiomelanocortin products. Brain Res. 541: 89-92, 1991.
43. Rothwell, N. J., and R. A. LeFeuvre. Thermogenesis, brown adipose tissue and dexfenfluramine in animal studies. Int. J. Obes. 16: S67-S71, 1992.
44. Sawchenko, P. E., and L. W. Swanson. Localization, colocalization, and plasticity of corticotropin-releasing factor immunoreactivity in rat brain. Federation Proc. 44: 221-227, 1985.
45. 2c. serotonin receptors. Nature Lond. 374: 542-546, 1995.
46. Van de Kar, L. D., and M. S. Brownfield. Serotonergic neurons and neuroendocrine function. News Physiol. Sci. 8: 202-207, 1993.