Reducing the oral quinine-quinidine-cinchonin (Quinimax®) treatment of uncomplicated malaria to three days does not increase the recurrence of attacks among children living in a highly endemic area of Senegal

Transactions of the Royal Society of Tropical Medicine and Hygiene

Volumn 90, Issue 2, 1996, Pages 175-178

  Regier, Christophe ^a   Brau, Regis ^a   Tall, Adama ^a   Cisse, Badara ^a   Trape, Jean François ^b  

^a INSTITUT PASTEUR DE DAKAR   (Senegal)

^b INSTITUT DE RECHERCHE POUR LE DÉVELOPPEMENT   (Senegal)

Author keywords

Chemotherapy; Children; Malaria; Plasmodium falciparum; Quinimax ; Senegal

Indexed keywords

ANTIMALARIAL AGENT; CHLOROQUINE; FANSIDAR; QUINIMAX;

ADOLESCENT; ARTICLE; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; HUMAN; IMMUNITY; INFANT; MAJOR CLINICAL STUDY; MALARIA; MALE; ORAL DRUG ADMINISTRATION; PLASMODIUM FALCIPARUM; RANDOMIZED CONTROLLED TRIAL; RECURRENCE RISK; SENEGAL;

EID: 0029944847     PISSN: 00359203     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0035-9203(96)90128-5     Document Type: Article

References (28)

1. Björkman, A. & Phillips-Howard, P. A. (1990). The epidemiology of drug-resistant malaria. Transactions of the Royal Society of Tropical Medicine and Hygiene, 84, 177-180.
2. Björkman, A., Willcox, M., Marbiah, N. & Payne, D. (1991). Susceptibility of Plasmodium falciparum to different doses of quinine in vivo and to quinine and quinidine in vitro in relation to chloroquine in Liberia. Bulletin of the World Health Organization, 69, 459-465.
3. Bloland, P. B., Lackritz, E. M., Kazembe, P. N., Were, J. B. O., Steketee, R. & Campbell, C. C. (1993). Beyond chloroquine: implications of drug resistance for evaluating malaria therapy efficacy and treatment policy in Africa. Journal of Infectious Diseases, 167, 932-937.
4. Brandicourt, O., Druilhe, P., Diouf, F., Brasseur, P., Turk, P. & Danis, M. (1986). Decreased sensitivity to chloroquine and quinine of some Plasmodium falciparum strains from Senegal in September 1984. American Journal of Tropical Medicine and Hygiene, 35, 717-721.
5. Brasseur, P., Kouamouo, J., Brandicourt, O., Moyou-Somo, R. & Druilhe, P. (1992). Multidrug resistant falciparum malaria in Cameroon. I. Stable figures of prevalence of chloroquine and quinine resistant isolates in the original foci. American Journal of Tropical Medicine and Hygiene, 46, 1-7.
6. Bruce-Chwatt, L. J. (1987). Quinine and the mystery of black-water fever. Acta Leidensia, 55, 181-196.
7. Carme, B., Yombi, B., Bouquety, J. C., Plassard, H., Nzingnula, S., Senga, J. & Akani, I. (1992). Child morbidity and mortality due to cerebral malaria in Brazzaville, Congo. A retrospective and prospective hospital-based study 1983-1989. Tropical Medicine and Parasitology, 43, 173-176.
8. Contamin, H., Fandeur, T., Rogier, C., Bonnefoy, S., Konaté, L., Trape, J. F. & Mercereau-Ouijalon, O. (in press). Molecular typing of Plasmodium falciparum isolates collected during successive clinical malaria episodes in Senegalese children. American Journal of Tropical Medicine and Hygiene.
9. Deloron, P., Lepers, J. P., Verdier, F., Chougnet, C., Remananmirija, J. A., Andriamangatiana-Rason, M. D., Coulanges, P. & Jaureguiberry, G. (1989). Efficacy of a 3-day oral regimen of a quinine-quinidine-cinchonin association (Quinimax®) for treatment of falciparum malaria in Madagascar. Transactions of the Royal Society of Tropical Medicine and Hygiene, 83, 751-754.
10. Druilhe, P., Brandicourt, O., Chongsuphajaisiddhi, T. & Berthe, J. (1988). Activity of a combination of three cinchona bark alkaloids against Plasmodium falciparum in vitro. Antimicrobial Agents and Chemotherapy, 32, 250-254.
11. Feller-Dansokho, E., Ki-Zerbo, G. & Badiane, S. (1994). Prise en charge diagnostique et thérapeutique de l'accès palustre simple dans la région de Dakar, Sénégal. Annales de la Société Belge de Médecine Tropicale, 74, 291-300.
12. Foster, S. D. (1991). Pricing, distribution and use of antimalarial drugs. Bulletin of the World Health Organization, 69, 349-363.
13. Greenberg, A. E., Ntumbanzondo, M., Ntula, N., Mawa, L., Howell, J. & Davachi, F. (1989). Hospital-based surveillance of malaria related paediatric morbidity and mortality in Kinshasa, Zaire. Bulletin of the World Health Organization, 67, 189-196.
14. Hosmer, D. W. & Lemeshow, S. (1989). Applied Logistic Regression. New York: Wiley-Interscience.
15. Jambou, R., Abissegue, B., Gelas, H., Ghipponi, P. M., Farinotti, R., Le Bras, J. & Hengy, C. (1990). L'accès palustre simple en zone de haut niveau de résistance à la chloroquine. I. Evaluation d'un traitement court par la quinine. Bulletin de la Société de Pathologie Exotique, 83, 46-52.
16. Kremsner, P. G., Winkler, S., Brandts, C., Neifer, S., Bienzle, U. & Graninger, W. (1994). Clindamycin in combination with chloroquine or quinine is an effective therapy for uncomplicated Plasmodium falciparum malaria in children from Gabon. Journal of Infectious Diseases, 169, 467-470.
17. Manson-Bahr, P. E. C. (1946). Blackwater fever. Manson's Tropical Diseases, 12th edition. London: Cassell, pp. 72-80.
18. Mount, D. L., Nahlen, B. L., Patchen, L. C. & Churchill, F. C. (1989). Adaptations of the Saker-Solomons test: simple, reliable colorimetric field assays for chloroquine and metabolites in urine. Bulletin of the World Health Organization, 67, 295-300.
19. Rogier, C. & Trape, J.-F. (1993). Malaria attacks in children exposed to high transmission: who is protected? Transactions of the Royal Society of Tropical Medicine and Hygiene, 87, 245-246.
20. Rogier, C., Commenges, D. & Trape, J. F. (in press). Evidence for an age-dependent pyrogenic threshold of Plasmodium falciparum parasitemia in highly endemic populations. American Journal of Tropical Medicine and Hygiene.
21. Salako, L. A. (1984). Toxicity and side-effects of antimalarials in Africa: a critical review. Bulletin of the World Health Organization, 62, supplement, 63-68.
22. Stiratelli, R., Laird, N. M. & Ware, J. H. (1984). Random-effects models for serial observations with binary response. Biometrics, 40, 961-971.
23. Trape, J. F. (1985). Rapid evaluation of malaria parasite density and standardization of thick smear examination for epidemiological investigations. Transactions of the Royal Society of Tropical Medicine and Hygiene, 79, 181-184.
24. Trape, J. F., Peelman, P. & Morault-Peelman, B. (1985). Criteria for diagnosing clinical malaria among a semi-immune population exposed to intense and perennial transmission. Transactions of the Royal Society of Tropical Medicine and Hygiene, 79, 435-442.
25. Trape, J. F., Rogier, C., Konate, L., Diagne, N., Bouganali, H., Canque, B., Legros, F., Badji, A., Ndiaye, G., Ndiaye, P., Brahimi, K., Faye, O., Druilhe, P. & Pereira da Silva, L. (1994). The Dielmo project: a longitudinal study of natural malaria infection and the mechanisms of protective immunity in a community living in a holoendemic area of Senegal. American Journal of Tropical Medicine and Hygiene, 51, 123-137.
26. WHO (1990). Practical Chemotherapy of Malaria. Geneva: World Health Organization, Technical Report Series, no. 805.
27. Wilson, D. B. (1939). Implications of malarial endemicity in East Africa. Transactions of the Royal Society of Tropical Medicine and Hygiene, 32, 435-465.
28. Zeger, S. L., Liang, K. Y. & Albert, P. S. (1988). Models for longitudinal data: a generalized estimating equation approach. Biometrics, 44. 1049-1060.