The first synthesis of optically pure (+)-and (-)-isokotanin A and the assignment of their absolute configuration

Tetrahedron Letters

Volumn 37, Issue 17, 1996, Pages 3015-3018

  Lin, Guo Qiang ^a   Zhong, Min ^a  

^a SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

COUMARIN DERIVATIVE; ISOKOTANIN A; UNCLASSIFIED DRUG;

ARTICLE; CHIRALITY; DRUG STRUCTURE; DRUG SYNTHESIS;

EID: 0029944545     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)00457-1     Document Type: Article

References (14)

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2. Lin, G.-Q. ; Zhong, M. Huaxue Xuebao, in press.
3. a. Nelson, T. D. ; Meyers, A. I. J. Org. Chem., 1994, 59(9), 2577 .
4. b. Nelson, T. D. ; Meyers, A. I. J. Org. Chem., 1994, 59(9), 2655 and references cited therein..
5. Musso, H.; Steckelberg, W. Chem. Ber., 1968, 101, 1510.
6. (R)-2a and (S)-2b were prepared according to the following lit.: a. Ishii, H.; Ishikawa, T.; Deushi, T.; Harada, K.-I.; Watanabe, T.; Ueda, E.; Ishida, T.; Sakamoto, M.; Kawanabe, E.; Takahashi, T.; Ichikawa, Y.-I.; Takizawa, K.; Masuda, T.; Chen, I.-S. Chem. Pharm. Chem., 1983, 31(9), 3024.
7. b. Haseltine, J. N.; Cabal, M. P.; Mantl, N. B. ; Iwasawa, N.; Yamashita, D. S.; Coleman, R. S.; Danishefsky, S. T.; Schulte, G. K. J. Am. Chem. Soc., 1991, 113(10), 3850.
8. c. references and notes 3 of this paper.
9. +) 616.2997, found 616.2995.
10. 3).
11. Moorlag, H.; Meyers, A. I. Tetrahedron Lett., 1993, 34(44), 6993.
12. 6: C, 67.03; H, 6.18. Found: C, 66.72; H, 6.38.
13. Suzuki, E.; Katsuragawa, B.; Inoue, S. Synthesis, 1978, 2, 144.
14. +) 438.1314, found 438.1263.