Structural flexibility and functional versatility of mammalian P450 enzymes

FASEB Journal

Volumn 10, Issue 7, 1996, Pages 683-689

  Negishi, Masahiko ^a,b   Uno, Tomohide ^a   Darden, Thomas A ^a   Sueyoshi, Tatsuya ^a   Pedersen, Lee G ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

DHEA specificity; polarity; side chains; substrate recognition sites

Indexed keywords

ALANINE; AMINO ACID; CYTOCHROME P450; ENVIRONMENTAL CHEMICAL; OXYGENASE; PRASTERONE; TESTOSTERONE; VALINE;

AMINO ACID SUBSTITUTION; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; HUMAN; HYDROXYLATION; NONHUMAN; PRIORITY JOURNAL; REVIEW; SITE DIRECTED MUTAGENESIS; STEREOSPECIFICITY;

BACTERIA (MICROORGANISMS); MAMMALIA;

EID: 0029944181     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fasebj.10.7.8635685     Document Type: Review

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