Design, synthesis and topoisomerase II inhibition activity of 4'-demethylepipodophyllotoxin-lexitropsin conjugates

Anti-Cancer Drug Design

Volumn 11, Issue 4, 1996, Pages 325-338

  Gupta, Rajan ^a   Al Said, Naim H ^a   Oreski, Bernadette ^b   Lown, J William ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b NAEJA Pharmaceutical Inc   (Canada)

Author keywords

4' demethylepipodophyllotoxin; Conjugates; Inhibition; Lexitropsin; Topoisomerase II

Indexed keywords

DNA FRAGMENT; DNA TOPOISOMERASE (ATP HYDROLYSING); EPIPODOPHYLLOTOXIN DERIVATIVE; LEXITROPSIN;

ARTICLE; CELL STRAIN KB; CONTROLLED STUDY; CYTOSTASIS; DNA SEQUENCE; DRUG CONJUGATION; DRUG DESIGN; DRUG DNA INTERACTION; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS; BASE SEQUENCE; CATALYSIS; CELL SURVIVAL; DNA TOPOISOMERASES, TYPE II; DNA, RECOMBINANT; DRUG DESIGN; ENZYME INHIBITORS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; NETROPSIN; PODOPHYLLOTOXIN; TUMOR CELLS, CULTURED;

EID: 0029944095     PISSN: 02669536     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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