Relationship of cellular energy parameters to cytotoxicity for AG-17, lonidamine and cyclocreatine in four human tumor cell lines

International Journal of Oncology

Volumn 8, Issue 5, 1996, Pages 865-873

  Ara, Gulshan ^a   Teicher, Beverly A ^a  

^a DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

AG 17; Cyclocreatine; Lonidamine; Mitochondrial toxins; Tyrphostin

Indexed keywords

3,5 DI TERT BUTYL 4 HYDROXYBENZYLIDENEMALONONITRILE; ADENOSINE TRIPHOSPHATE; CREATINE KINASE; CYCLOCREATINE; CYTOCHROME C OXIDASE; LONIDAMINE;

ARTICLE; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENERGY METABOLISM; HUMAN; HUMAN CELL; PRIORITY JOURNAL; TUMOR CELL LINE;

EID: 0029943801     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijo.8.5.865     Document Type: Article

References (2)

1. Warburg O: On respiratory impairment in cancer cells. Science 124: 269, 1956.
2. Walliman T, Wyss M, Brdiczka D, Nicolay K and Eppenberger HM: Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the 'phosphocreatine circuit' for cellular energy homeostasis. Biochem J 281: 21-40, 1992.