The enhanced effect of parenteral nutrition on hepatotoxicity

Nutrition

Volumn 12, Issue 1, 1996, Pages 30-35

  Denno, Ryusuke ^a   Rounds, Jan D ^a   Faris, Ramona ^a   Holejko, Lourdes B ^a   Wilmore, Douglas W ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

acetaminophen; cytochrome P 450; drug induced hepatotoxicity; glutamine; glutathione; polymyxin B; total parenteral nutrition

Indexed keywords

CYTOCHROME P450; GLUCOSE; GLUTAMINE; GLUTATHIONE; LIVER ENZYME; PARACETAMOL; POLYMYXIN B;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL COLONIZATION; CONTROLLED STUDY; ENTERIC FEEDING; FOOD COMPOSITION; GASTROSTOMY; LIVER TOXICITY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SURVIVAL RATE; TOTAL PARENTERAL NUTRITION;

ANIMALIA; BACTERIA (MICROORGANISMS); RATTUS NORVEGICUS;

EID: 0029943737     PISSN: 08999007     EISSN: None     Source Type: Journal    
DOI: 10.1016/0899-9007(95)00014-3     Document Type: Article

References (26)

1. Kudsk KA, Croce MA, Fabian TC, et al. Enteral versus parenteral feeding: Effects on septic morbidity after blunt and penetrating abdominal trauma. Ann Surg 1992;215:503
2. Levine GM, Deren JJ, Steiger E, et al. Role of oral intake in maintenance of gut mass and disaccharide activity. Gastroenterology 1974;67:975
3. Kudsk KA, Carpenter G, Petersen S, et al. Effect of enteral and parenteral feeding in malnourished rats with E. coli-hemoglobin adjuvant peritonitis. J Surg Res 1981;31:105
4. Saito H, Trocki O, Alexander JW, et al. The effect of route of nutrient administration on the nutritional state, catabolic hormone secretion, and gut mucosal integrity after burn injury. JPEN 1987;11:1
5. Delany HM, John J, Teh EL, et al. Contrasting effects of identical nutrients given parenterally or enterally after 70% hepatectomy. Am J Surg 1994;167:135
6. Moore FA, Moore EE, Jones TN, et al. TEN versus TPN following major abdominal trauma: Reduced septic morbidity. J Trauma 1989;29:916
7. Wilmore DW, Smith RJ, O'Dwyer ST, et al. The gut: A central organ after surgical stress. Surgery 1988;104:917
8. Keim NL. Nutritional effectors of hepatic steatosis induced by parenteral nutrition in the rat. JPEN 1987;11:18
9. Culebras JM, Garcia-Vielba J, Garcia-Diez F, et al. The effects of total parenteral nutrition on the hepatic handling of bilirubin in the rats. JPEN 1993;17:125
10. Nelson SD. Molecular mechanisms of the hepatotoxicity caused by acetaminophen. Sem Liv Dis 1990;10:267
11. Haskel YH, Xu D, Lu Q, et al. The modulatory role of gut hormones in elementary diet and intravenous total parenteral nutrition-induced bacterial translocation in rats. JPEN 1994;18:159
12. Robinson MK, Hong RW, Rounds JD, et al. Glutathione depletion enhances bacterial translocation and alters immunologic status. Surg Forum 1991;42:65
13. Souba WW, Klimberg VS, Hautamaki RD, et al. Oral glutamine reduces bacterial translocation following abdominal radiation. J Surg Res 1990;48:1
14. Pappo I, Bercovier H, Berry EM, et al. Polymyxin B reduces total parenteral nutrition-associated hepatic steatosis by its antibacterial activity and by blocking deleterious effects of lipopolysaccharide. JPEN 1992;16:529
15. O'Dwyer ST, Smith RJ, Hwang TL, et al. Maintenance of small bowel mucosa with glutamine-enriched parenteral nutrition. JPEN 1989;13:579-585
16. Helton WS, Smith RJ, Rounds J, et al. Glutamine prevents pancreatic atrophy and fatty liver during elemental feeding. J Surg Res 1990;48:297
17. Hong RW, Rounds JD, Helton WS, et al. Glutamine preserves liver glutathione after lethal hepatic injury. Ann Surg 1992;215:114
18. Brown E, Hong R, Wilmore W. Adaptation of a coupled enzymatic recycling assay for glutathione (GSH) to the Abbott VP. Clin Chem 1992;38:1032
19. Griffith OW. Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine. Anal Biochem 1980;106:207
20. Kaplowitz N. Drug-induced hepatotoxicity. In: Gitnick G, eds. Current hepatology. Chicago:Year Book Medical Publisher, 1987:69
21. Leaseburge LA, Winn NJ, Schloerb PR. Liver test alterations with total parenteral nutrition and nutritional status. JPEN 1992;16:348
22. Knodell RG, Spector MH, Brooks DA, et al. Alterations in pentobarbital pharmacokinetics in response to parenteral and enteral alimentation in the rat. Gastroenterology 1980;79:1211
23. Knodell RG, Steele MM, Cerra FB, et al. Effects of parenteral and enteral hyperalimentation on hepatic drug metabolism in the rat. J Pharmacol Exp Ther 1984; 229:589
24. Knodell RG, Whitmer DI, Holman RT. Influence of hyperalimentation on rat hepatic microsomal fluidity and function. Gastroenterology 1990;98:1320
25. Stramentinoli G, Pezzoli C, Galli-Kienle M. Protective role of S-adenosyl-L-methionine against acetaminophen induced mortality and hepatotoxicity in mice. Biochem Pharm 1979; 28:3567
26. Mitchell MC, Schenker S, Avant GR, et al. Cimetidine protects against acetaminophen in rats. Gastroenterology 1981;81:1052