Frequency of Ki-ras mutations and DNA alkylation in colorectal tissue from individuals living in Manchester

Molecular Carcinogenesis

Volumn 16, Issue 1, 1996, Pages 12-19

  Jackson, Peta E ^a   Hall, C Nick ^b   Badawi, Alaa F ^a,c   O'Connor, Peter J ^a   Cooper, Donald P ^a   Povey, Andrew C ^a,d  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b WYTHENSHAWE HOSPITAL   (United Kingdom)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

colorectal cancer; Ki ras; O6 methyldeoxyguanosine

Indexed keywords

6 O METHYLDEOXYGUANOSINE; UNCLASSIFIED DRUG;

ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; DNA ALKYLATION; GENE MUTATION; HUMAN; HUMAN TISSUE; ONCOGENE K RAS; PRIORITY JOURNAL;

BASE SEQUENCE; COLON; COLORECTAL NEOPLASMS; DNA DAMAGE; DNA PRIMERS; ENGLAND; GENES, RAS; GUANINE; HUMANS; METHYLATION; MOLECULAR SEQUENCE DATA; POINT MUTATION; PROTO-ONCOGENE PROTEINS P21(RAS);

SIGMOIDEA;

EID: 0029943556     PISSN: 08991987     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2744(199605)16:1<12::AID-MC3>3.0.CO;2-Q     Document Type: Article

References (45)

1. Fearon ER. Genetic alterations underlying colorectal tumorigenesis. Cancer Surv 12:119-136, 1992.
2. Vogelstein B, Fearon ER, Hamilton SR, et al. Genetic alterations during colo-rectal tumour development. N Engl J Med 319:525-532, 1988.
3. Harris CC, Hollstein M. Clinical implications of the p53 tumorsuppressor gene. N Engl J Med 329:1313-1327, 1993.
4. Nakamura Y. The role of the adenomatous polyposis coll (APC) gene in human cancers. Adv Cancer Res 62:65-87, 1993.
5. Burmer GC, Loeb LA. Mutations in the KRAS 2 oncogene during progressive stages of human colon carcinoma. Proc Natl Acad Sci USA 86:2403-2407, 1989.
6. Bos JL. Ras oncogenes in human cancer: A review. Cancer Res 49:4682-4689, 1989.
7. Zaridze DG. Environmental etiology of large bowel cancer. J Natl Cancer Inst 70:389-400, 1983.
8. Kune GA. The causes of colorectal cancer. Gastrointestinal Cancer 1:25-31, 1995.
9. Sugimura T. Multistep carcinogenesis. Science 258:603-607, 1992.
10. Bingham SA, Pignatelli B, Thullier P, Cummings JH, O'Neill IK. Effect of meat and bran on intestinal N-nitrosation. Abstract. Gastroenterology 104:A389, 1993.
11. Povey AC, Schiffman MH, Taffe BG, Harris CC. Laboratory and epidemiologic studies of fecapentaenes. Mutat Res 259:387-397, 1991.
12. Suzuki K, Bruce WR, Baptista J, Furrer R, Vaughan DJ, Krepinsky JJ. Characterization of cytotoxic steroids in human faeces and their putative role in the etiology of human colonic cancer. Cancer Lett 33:307-316, 1986.
13. Hall CN, Badawi AF, O'Connor PJ, Saffhill R. The detection of alkylation damage in the DNA of human gastrointestinal tissues. Br J Cancer 64:59-63, 1991.
14. Saffhill R, Margison GP, O'Connor PJ. Mechanisms of carcinogenesis induced by alkylating agents. Biochim Biophys Acta 823:111-146, 1985.
15. 6-methylguanine built into a unique site in a viral genome. Proc Natl Acad Sci USA 81:6271-6275, 1984.
16. Narisawa T, Weisburger JH. Colon cancer induction in mice by intra-rectal instillation of N-methyl-N-nitrosourea. Proc Soc Exp Biol Med 148:166-169, 1975.
17. Jacoby RF, Lior X, Teng B-B, Davidson NO, Brasitus TA. Mutations in the K-ras oncogene induced by 1,2-dimethylhydrazine in preneoplastic and neoplastic rat colonic mucosa. J Clin Invest 87:624-630, 1991.
18. Hultman T, Stahl S, Homes E, Uhlen M. Direct solid phase sequencing of genomic and plasmid DNA using magnetic beads as solid support. Nucleic Acids Res 17:4937-4946, 1989.
19. Sanger F, Niklen S, Coulson AR. DNA sequencing with chainterminating inhibitors. Proc Natl Acad Sci USA 74:5463-5467, 1977.
20. Badawi AF, Mostafa MH, Aboul-Azm T, Haboubi NY, O'Connor PJ, Cooper DP. Promutagenic methylation damage in bladder DNA from patients with bladder cancer associated with schistosomiasis and from normal individuals. Carcinogenesis 13:877-881, 1992.
21. 6-methyldeoxyguanosine in oesophageal DNA among individuals at high risk of oesophageal cancer. Int J Cancer 36:661-665, 1985.
22. Massey RC, Key PE, Mallett AK, Rowland IR. An investigation of the endogenous formation of apparent total N-nitroso compounds in conventional microflora and germ-free rats. Food Chem Toxicol 26:595-600, 1988.
23. Rowland IR, Granli T, Bockman OC, Key PE, Massey RC. Endogenous N-nitrosation in man assessed by measurement of apparent total N-nitroso compounds in faeces. Carcinogenesis 12:1395-1401, 1991.
24. Marletta MA. Mammalian synthesis of nitrite, nitrate, nitric oxide and N-nitrosating agents. Chem Res Toxicol 1:249-257, 1988.
25. Puju S, Shuker DEG, Bishop WW, Falchuk KR, Tannenbaum SR, Thilly WG. Mutagenicity of N-nitroso bile acid conjugates in Salmonella typhimurium and diploid human lymphoblasts. Cancer Res 42:2601-2604, 1982.
26. Mostafa MH, Helmi S, Badawi AF, Tricker AR, Spiegelhalder B, Preussmann R. Nitrate, nitrite and volatile nitrosocompounds in the urine of Schistosoma haematobium and Schistosoma mansoni infected patients. Carcinogenesis 15:619-625, 1994,
27. Hussain SP, Aguilar F, Cerutti P. Mutagenesis of codon 248 of the human p53 tumor suppressor gene by N-ethyl-N-nitrosourea. Oncogene 9:13-18, 1994.
28. Ohgaki H, Hard GC, Hirota N, Maekawa A, Takahashi M, Kleihues P. Selective mutation of codons 204 and 213 of the p53 gene in rat tumors induced by alkylating N-nitroso compounds. Cancer Res 52:2995-2998, 1992.
29. Karran P, Bignami M. DNA damage tolerance, mismatch repair and genome instability. Bioessays 16:833-839, 1994.
30. Shibata D, Peinado MA, Ionov Y, Malkhosyan S, Perucho M. Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation. Nat Genet 6:273-281, 1994.
31. Salhab N, Jones DJ, Bos JL, Kinsella A, Schofield PF. Detection of ras gene alterations and ras proteins in colorectal cancer. Dis Colon Rectum 32:659-664, 1989.
32. Boughdady IS, Schofield PF, Kinsella AR. Incidence of Ki-ras mutations at codon 12 in colorectal adenomas and carcinomas. In: Paterson Institute Annual Report, Paterson Institute, Manchester, 1990, pp. 25-26.
33. Takeshima Y, Seyama T, Bennett WP, et al. p53 mutations in lung cancers from non-smoking atomic-bomb survivors. Lancet 342:1520-1521, 1993.
34. Suzuki H, Takakashi T, Kuroishi T, et al. p53 mutations in non-small cell lung cancer in Japan: Association between mutations and smoking. Cancer Res 52:734-736, 1992.
35. Cooper DP, O'Connor PJ, Povey AC, Rafferty JR. Cell and molecular mechanisms in chemical carcinogenesis. In: Peckham M, Pinedo B and Veronesi U (eds), Oxford Textbook of Oncology, Vol 1. Oxford University Press, Oxford, 1995, pp. 135-147.
36. 6-alkylguanine-DNA alkyltransferase. Science 259:219-222, 1993.
37. Karran P, Bignami M. DNA damage tolerance, mismatch repair and genome instability. Bioessays 16:833-839, 1994.
38. Endo H, Schut HAJ, Snyderwine EG. Mutagenic specificity of 2-amino-3-methylimidazo[4,5-F]quinoline and 2-amino-1-methyl-6-phenylimidazo[4,5-B] pyridine in the SUPF shuttle vector system. Cancer Res 54:3745-3751, 1994.
39. Wink DA, Kasprzak KS, Maragos CM, et al. DNA deaminating ability and genotoxicity of nitric oxide and its progenitors. Science 254:1001-1003, 1991.
40. Breimer LH. Molecular mechanisms of oxygen radical carcinogenesis and mutagenesis: The role of DNA base damage. Mol Carcinog 3:188-197, 1990.
41. Rideout III WM, Coetzee GA, Oluni AF, Jones PA. 5-methylcytosine as an endogenous mutagen in the human LDL receptor and p53 genes. Science 249:1288-1290, 1990.
42. Shen J-G, Rideout III WM, Jones PA. The rate of hydrolytic deamination of 5-methylcytosine in double-stranded DNA. Nucleic Acids Res 22:972-976, 1994.
43. Lundberg JON, Hellstrom PM, Lundberg JM, Alving K. Greatly increased luminal nitric oxide in ulcerative colitis. Lancet 344:1673-1674, 1994.
44. Ohshima H, Bartsch H. Chronic infections and inflammatory processes as cancer risk factors: Possible role of nitric oxide in carcinogenesis. Mutat Res 305:253-264, 1994.
45. Frenkel K. Carcinogen-mediated oxidant formation and oxidative DNA damage. Pharmacol Ther 53:127-166, 1992.