Roles of the sequence encoding tobacco etch virus capsid protein in genome amplification: Requirements for the translation process and a cis-active element

Journal of Virology

Volumn 70, Issue 7, 1996, Pages 4370-4379

  Mahajan, Sunita ^a   Dolja, Valerian V ^b   Carrington, James C ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b OREGON STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CIS ACTING ELEMENT; VIRUS CAPSID ANTIGEN;

ARTICLE; DELETION MUTANT; FRAMESHIFT MUTATION; GENE AMPLIFICATION; NONHUMAN; PLANT VIRUS; PRIORITY JOURNAL; PROTOPLAST; RNA REPLICATION; RNA TRANSLATION; STOP CODON; TOBACCO VIRUS; VIRUS GENOME;

EID: 0029943535     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.7.4370-4379.1996     Document Type: Article

References (46)

1. Allison, R., R. E. Johnston, and W. G. Dougherty. 1986. The nucleotide sequence of the coding region of tobacco etch virus genomic RNA: evidence for the synthesis of a single polyprotein. Virology 154:9-20.
2. Allison, R. F., W. G. Dougherty, T. D. Parks, L. Willis, R. F. Johnston, M. Kelly, and F. B. Armstrong. 1985. Biochemical analysis of the capsid protein gene and capsid protein of tobacco etch virus: N-terminal amino acids are located on the virion's surface. Virology 147:309-316.
3. Atreya, C. D., P. L. Atreya, D. W. Thornbury, and T. P. Pirone. 1992. Site-directed mutations in the potyvirus HC-PRO gene affect helper component activity, virus accumulation, and symptom expression in infected tobacco plants. Virology 191:106-111.
4. Atreya, C. D., R. Raccah, and T. P. Pirone. 1990. A point mutation in the coat protein abolishes aphid transmissibility of a potyvirus. Virology 178:161-165.
5. Atreya, P. L., C. D. Atreya, and T. P. Pirone. 1991. Amino acid substitutions in the coat protein result in loss of insect transmissibility of a plant virus. Proc. Natl. Acad. Sci. USA 88:7887-7891.
6. Atreya, P. L., J. J. Lopez-Moya, M. Chu, C. D. Atreya, and T. P. Pirone. 1995. Mutational analysis of the coat protein N-terminal amino acids involved in potyvirus transmission by aphids. J. Gen. Virol. 76:265-270.
7. Ball, L. A., and Y. Li. 1993. cis-acting requirements for the replication of flock house virus RNA 2. J. Virol. 67:3544-3551.
8. Berkhout, B., and J. Van Duin. 1985. Mechanism of translational coupling between coat protein and replicase genes of RNA bacteriophage MS2. Nucleic Acids Res. 13:6955-6967.
9. Berkhout, B., A. Van Strien, J. H. Van Boom, J. Van Westrenen, and J. Van Duin. 1987. Lysis gene of bacteriophage MS2 is activated by translation termination at the overlapping coat gene. J. Mol. Biol. 195:517-524.
10. Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
11. Carrington, J. C., and W. G. Dougherty. 1987. Small nuclear inclusion protein encoded by a plant potyvirus genome is a protease. J. Virol. 61:2540-2548.
12. Carrington, J. C., R. Haldeman, V. V. Dolja, and M. A. Restrepo-Hartwig. 1993. Internal cleavage and trans-proteolytic activities of the VPg-proteinase (NIa) of tobacco etch potyvirus in vivo. J. Virol. 67:6995-7000.
13. Chang, Y. C., M. Borja, H. B. Scholthof, A. O. Jackson, and T. J. Morris. 1995. Host effects and sequences essential for accumulation of defective interfering RNAs of cucumber necrosis and tomato bushy stunt tombusviruses. Virology 210:41-53.
14. Dolja, V. V., R. Haldeman, N. L. Robertson, W. G. Dougherty, and J. C. Carrington. 1994. Distinct functions of capsid protein in assembly and movement of tobacco etch potyvirus in plants. EMBO J. 13:1482-1491.
15. Dolja, V. V., R. Haldeman-Cahill, A. E. Montgomery, K. A. VandenBosch, and J. C. Carrington. 1995. Capsid protein determinants involved in cell-to-cell and long distance movement of tobacco etch potyvirus. Virology 207:1007-1016.
16. Dolja, V. V., H. J. McBride, and J. C. Carrington. 1992. Tagging of plant potyvirus replication and movement by insertion of β-glucuronidase into the viral polyprotein. Proc. Natl. Acad. Sci. USA 89:10208-10212.
17. Dougherty, W. G., S. M. Cary, and T. D. Parks. 1989. Molecular genetic-analysis of a plant virus polyprotein cleavage site: a model. Virology 171:356-364.
18. Dougherty, W. G., and B. L. Semler. 1993. Expression of virus-encoded proteinases: functional and structural similarities with cellular enzymes. Microbiol. Rev. 57:781-822.
19. Dougherty, W. G., L. Willis, and R. E. Johnston. 1985. Topographical analysis of tobacco etch virus capsid protein epitopes. Virology 144:66-72.
20. French, R., and P. Ahlquist. 1987. Intercistronic as well as terminal sequences are required for efficient amplification of brome mosaic virus RNA3. J. Virol. 61:1457-1465.
21. Goodwin, J., K. Chapman, S. Swaney, T. D. Parks, E. Wernsman, and W. G. Dougherty. 1996. Genetic and biochemical dissection of transgenic RNA-mediated virus resistance. Plant Cell 8:95-105.
22. Jaeger, J. A., D. H. Turner, and M. Zucker. 1989. Improved predictions of secondary structure for RNA. Proc. Natl. Acad. Sci. USA 86:7706-7710.
23. Jefferson, R. A. 1987. Assaying chimeric genes in plants: the GUS gene fusion system. Plant Mol. Biol. Rep. 5:387-405.
24. Kasschau, K. D., and J. C. Carrington. 1995. Requirement for HC-Pro processing during genome amplification of tobacco etch potyvirus. Virology 209:268-273.
25. Kim, Y. N., Y. S. Jeong, and S. Makino. 1993. Analysis of cis-acting sequences essential for coronavirus defective interfering RNA replication. Virology 197:53-63.
26. Klein, P. G., R. R. Klein, E. Rodríguez-Cerezo, A. G. Hunt, and J. G. Shaw. 1994. Mutational analysis of the tobacco vein mottling virus genome. Virology 204:759-769.
27. Kunkel, T. A., J. D. Roberts, and R. Zakour. 1987. Rapid and efficient site-specific mutagenesis without phenotypic selection. Methods Enzymol. 154:367-382.
28. Li, X. H., and J. C. Carrington. 1995. Complementation of tobacco etch potyvirus mutants by active RNA polymerase expressed in transgenic cells. Proc. Natl. Acad. Sci. USA 92:457-461.
29. Lindbo, J. A., and W. G. Dougherly. 1992. Pathogen-derived resistance to a potyvirus: immune and resistant phenotypes in transgenic tobacco expressing altered forms of a potyvirus coat protein nucleotide sequence. Mol. Plant-Microbe Interact. 5:144-153.
30. Lindbo, J. A., and W. G. Dougherty. 1992. Untranslatable transcripts of the tobacco etch virus coat protein gene can interfere with tobacco etch virus replication in transgenic plants and protoplasts. Virology 189:725-733.
31. Lindbo, J. A., L. Silva-Rosales, W. M. Proebsting, and W. G. Dougherty. 1993. Induction of a highly specific antiviral state in transgenic plants: implications for regulation of gene expression and virus resistance. Plant Cell 5:1749-1759.
32. Negrutiu, I., R. Shillito, I. Potrykus, G. Biasini, and F. Sala. 1987. Hybrid genes in the analysis of transformation conditions. 1. Setting up a simple method for direct gene transfer in plant protoplasts. Plant Mol. Biol. 8:363-373.
33. Novak, J. E., and K. Kirkegaard. 1994. Coupling between genome translation and replication in an RNA virus. Genes Dev. 8:1726-1737.
34. Oh, C.-S., and J. C. Carrington. 1989. Identification of essential residues in potyvirus proteinase HC-Pro by site-directed mutagenesis. Virology 173:692-699.
35. Parks, T. D., K. K. Leuther, E. D. Howard, S. A. Johnston, and W. G. Dougherty. 1994. Release of proteins and peptides from fusion proteins using a recombinant plant virus proteinase. Anal. Biochem. 216:413-417.
36. Restrepo-Hartwig, M. A., and J. C. Carrington. 1994. The tobacco etch potyvirus 6-kilodalton protein is membrane associated and involved in viral replication. J. Virol. 68:2388-2397.
37. Riechmann, J. L., S. Lain, and J. A. Garcia. 1992. Highlights and prospects of potyvirus molecular biology. J. Gen. Virol. 73:1-16.
38. Shukla, D. D., P. M. Strike, S. L. Tracy, K. H. Gough, and C. W. Ward. 1988. The N and C termini of the coat proteins of potyviruses are surface-located and the N terminus contains the major virus-specific epitopes. J. Gen. Virol. 69:1497-1508.
39. Shukla, D. D., and C. W. Ward. 1989. Structure of potyvirus coat proteins and its application in the taxonomy of the potyvirus group. Adv. Virus Res. 36:273-314.
40. Slade, D. E., R. E. Johnston, and W. G. Dougherty. 1989. Generation and characterization of monoclonal antibodies reactive with the 49-kDa proteinase of tobacco etch virus. Virology 173:499-508.
41. Smith, H. A., S. L. Swaney, T. D. Parks, E. A. Wernsman, and W. G. Dougherty. 1994. Transgenic plant virus resistance mediated by untranslatable sense RNAs: expression, regulation, and fate of nonessential RNAs. Plant Cell 6:1441-1453.
42. van Bokhoven, H., O. Le Gall, D. Kasteel, J. Verver, J. Wellink, and A. van Kammen. 1993. Cis- and trans-acting elements in cowpea mosaic virus RNA replication. Virology 195:377-386.
43. Verchot, J., and J. C. Carrington. 1995. Debilitation of plant potyvirus infectivity by P1 proteinase-inactivating mutations and restoration by second-site modifications. J. Virol. 69:1582-1590.
44. Verchot, J., and J. C. Carrington. 1995. Evidence that the potyvirus P1 protein functions as an accessory factor for genome amplification. J. Virol. 69:3668-3674.
45. Weiland, J. J., and T. W. Dreher. 1993. Cis-preferential replication of the turnip yellow mosaic virus RNA genome. Proc. Natl. Acad. Sci. USA 90:6095-6099.
46. Zucker, M. 1989. On finding all suboptimal foldings of an RNA molecule. Science 244:48-52.