메뉴 건너뛰기




Volumn 6, Issue 3, 1996, Pages 316-321

Early steps in mammalian sex determination

Author keywords

[No Author keywords available]

Indexed keywords

TESTIS DETERMINING FACTOR;

EID: 0029943390     PISSN: 0959437X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-437X(96)80008-6     Document Type: Article
Times cited : (38)

References (58)
  • 1
    • 0028241430 scopus 로고
    • Sex determination and dosage compensation: Lessons from flies and worms
    • Parkhurst SM, Meneely PM: Sex determination and dosage compensation: lessons from flies and worms. Science 1994, 264:924-932.
    • (1994) Science , vol.264 , pp. 924-932
    • Parkhurst, S.M.1    Meneely, P.M.2
  • 2
    • 0029176442 scopus 로고
    • Sex determination and its pathology in man
    • Edited by Hall JC, Dunlap JC. San Diego: Academic Press
    • Schafer AJ: Sex determination and its pathology in man. In Advances in Genetics, vol 33. Edited by Hall JC, Dunlap JC. San Diego: Academic Press; 1995:275-329.
    • (1995) Advances in Genetics , vol.33 , pp. 275-329
    • Schafer, A.J.1
  • 4
    • 0027306801 scopus 로고
    • Rapid sequence evolution of the mammalian sex-determining gene SRY
    • Whitfield LS, Lovell-Badge R, Goodfellow PN: Rapid sequence evolution of the mammalian sex-determining gene SRY. Nature 1993, 364:713-715.
    • (1993) Nature , vol.364 , pp. 713-715
    • Whitfield, L.S.1    Lovell-Badge, R.2    Goodfellow, P.N.3
  • 5
    • 0027180071 scopus 로고
    • Rapid evolution of the sex determining locus in Old World mice and rats
    • Tucker PK, Lundrigan BL: Rapid evolution of the sex determining locus in Old World mice and rats. Nature 1993, 364:715-717.
    • (1993) Nature , vol.364 , pp. 715-717
    • Tucker, P.K.1    Lundrigan, B.L.2
  • 7
    • 0027936497 scopus 로고
    • Sex determination
    • Hawkins JR: Sex determination. Hum Mol Genet 1994, 3:1463-1467.
    • (1994) Hum Mol Genet , vol.3 , pp. 1463-1467
    • Hawkins, J.R.1
  • 8
    • 0028240486 scopus 로고
    • A novel mutation localized in the 3′ non HMG box region of the SRY gene in 46,XY gonadal dysgenesis
    • Tajima T, Nakae J, Shinohara N, Fujieda K: A novel mutation localized in the 3′ non HMG box region of the SRY gene in 46,XY gonadal dysgenesis. Hum Mol Genet 1994, 3:1187-1189.
    • (1994) Hum Mol Genet , vol.3 , pp. 1187-1189
    • Tajima, T.1    Nakae, J.2    Shinohara, N.3    Fujieda, K.4
  • 10
    • 0026643104 scopus 로고
    • The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures
    • Giese K, Cox J, Grosschedl R: The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures. Cell 1992, 69:185-195.
    • (1992) Cell , vol.69 , pp. 185-195
    • Giese, K.1    Cox, J.2    Grosschedl, R.3
  • 12
    • 0028999513 scopus 로고
    • Differences in the DNA binding properties of the HMG box domains of HMG1 and the sex determining factor SRY
    • Teo SH, Grasser KD, Thomas JO: Differences in the DNA binding properties of the HMG box domains of HMG1 and the sex determining factor SRY. Eur J Biochem 1995, 230:943-950.
    • (1995) Eur J Biochem , vol.230 , pp. 943-950
    • Teo, S.H.1    Grasser, K.D.2    Thomas, J.O.3
  • 14
    • 0025243412 scopus 로고
    • Expression of a candidate sex-determining gene during mouse testis differentiation
    • Koopman P, Munsterberg A, Capel B, Vivian N, Lovell-Badge R: Expression of a candidate sex-determining gene during mouse testis differentiation. Nature 1990, 348:450-452.
    • (1990) Nature , vol.348 , pp. 450-452
    • Koopman, P.1    Munsterberg, A.2    Capel, B.3    Vivian, N.4    Lovell-Badge, R.5
  • 16
    • 0025346057 scopus 로고
    • XY female mice resulting from a heritable mutation in the primary testis determining gene, Tdy
    • Lovell-Badge R, Robertson E: XY female mice resulting from a heritable mutation in the primary testis determining gene, Tdy. Development 1990, 109:635-646.
    • (1990) Development , vol.109 , pp. 635-646
    • Lovell-Badge, R.1    Robertson, E.2
  • 18
    • 0029048140 scopus 로고
    • Expression of Sry, the mouse sex determining gene
    • Hacker A, Capel B, Goodtellow P, Lovell-Badge R: Expression of Sry, the mouse sex determining gene. Development 1995, 121:1603-1614. This paper describes the use of RNase protection to provide a detailed analysis of Sry expression in the mouse genital ridge. A comparison with Amh expression defines a window of 20 hours between 10.5 and 11.5 dρc during which Sry must act.
    • (1995) Development , vol.121 , pp. 1603-1614
    • Hacker A1    Capel B2    Goodtellow P3    Lovell-Badge R4
  • 19
    • 0028151561 scopus 로고
    • Normal onset but prolonged expression, of Sry gene in the B6.Y(DOM) sex reversed mouse gonad
    • Lee CH, Taketo T: Normal onset but prolonged expression, of Sry gene in the B6.Y(DOM) sex reversed mouse gonad. Dev Biol 1994, 165:442-452.
    • (1994) Dev Biol , vol.165 , pp. 442-452
    • Lee, C.H.1    Taketo, T.2
  • 20
    • 0029161999 scopus 로고
    • Expression of a linear Sry transcript in the mouse genital ridge
    • Jeske YWA, Bowles J, Greenfield A, Koopman P: Expression of a linear Sry transcript in the mouse genital ridge. Nat Genet 1995, 10:480-482.
    • (1995) Nat Genet , vol.10 , pp. 480-482
    • Jeske, Y.W.A.1    Bowles, J.2    Greenfield, A.3    Koopman, P.4
  • 21
    • 0028243024 scopus 로고
    • Detection of circular and linear transcripts of Sry in preimplantation mouse embryos -differences in requirement for reverse-transcriptase
    • Boyer TR, Erickson RP: Detection of circular and linear transcripts of Sry in preimplantation mouse embryos -differences in requirement for reverse-transcriptase. Biochem Biophys Res Commun 1994, 198:492-496.
    • (1994) Biochem Biophys Res Commun , vol.198 , pp. 492-496
    • Boyer, T.R.1    Erickson, R.P.2
  • 22
    • 0028900116 scopus 로고
    • Expression of the mouse testis determining gene Sry in male preimplantatlon embryos
    • Qiu Ping C, Gaudette MF, Robinson DH, Crain WR: Expression of the mouse testis determining gene Sry in male preimplantatlon embryos. Mol Reprod Dev 1995, 40:196-204.
    • (1995) Mol Reprod Dev , vol.40 , pp. 196-204
    • Qiu Ping, C.1    Gaudette, M.F.2    Robinson, D.H.3    Crain, W.R.4
  • 25
    • 0029096665 scopus 로고
    • NMR spectroscoplc analysis of the DNA conformation induced by the human testis determining factor SRY
    • Werner MH, Bianchi ME, Gronenborn AM, Clore GM: NMR spectroscoplc analysis of the DNA conformation induced by the human testis determining factor SRY. Biochemistry 1995, 34:11998-12004.
    • (1995) Biochemistry , vol.34 , pp. 11998-12004
    • Werner, M.H.1    Bianchi, M.E.2    Gronenborn, A.M.3    Clore, G.M.4
  • 26
    • 0029075461 scopus 로고
    • Molecular basis of human 46,XY sex reversal revealed from the three dimensional solution structure of the human SRY DNA complex
    • Werner MH, Huth JR, Gronenborn AM, Clore GM: Molecular basis of human 46,XY sex reversal revealed from the three dimensional solution structure of the human SRY DNA complex. Cell 1995, 81:705-714. The authors have used NMR to determine the solution structure of the HMG-box of human SRY in complex with DNA. This has been the first sequence-specific HMG box structure to be described and has provided an insight into how sex-reversing mutations of SRY affect its interaction with DNA.
    • (1995) Cell , vol.81 , pp. 705-714
    • Werner, M.H.1    Huth, J.R.2    Gronenborn, A.M.3    Clore, G.M.4
  • 27
    • 0028657623 scopus 로고
    • Molecular basis of mammalian sexual determination: Activation of Müllerian inhibiting substance gene expression by SRY
    • Haqq CM, King C-Y, Ukiyama E, Falsafi S, Haqq TN, Donahoe PK, Weiss MA: Molecular basis of mammalian sexual determination: activation of Müllerian inhibiting substance gene expression by SRY. Science 1994, 266:1494-1500.
    • (1994) Science , vol.266 , pp. 1494-1500
    • Haqq, C.M.1    King, C.-Y.2    Ukiyama, E.3    Falsafi, S.4    Haqq, T.N.5    Donahoe, P.K.6    Weiss, M.A.7
  • 28
    • 0028201316 scopus 로고
    • Distinct DNA-binding properties of the high mobility group domain of murine and human SRY sex-determining factors
    • Giese K, Pagel J, Grosschedl R: Distinct DNA-binding properties of the high mobility group domain of murine and human SRY sex-determining factors. Proc Natl Acad Sci USA 1994, 91:3368-3372.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3368-3372
    • Giese, K.1    Pagel, J.2    Grosschedl, R.3
  • 29
    • 0027930743 scopus 로고
    • Sry is a transcriptional activator
    • Dubin RA, Ostrer H: Sry is a transcriptional activator. Mol Endocrinol 1994, 8:1182-1192.
    • (1994) Mol Endocrinol , vol.8 , pp. 1182-1192
    • Dubin, R.A.1    Ostrer, H.2
  • 30
    • 0028346028 scopus 로고
    • Sry protein enhances transcription of fos-related antigen-1 promoter constructs
    • Cohen DR, Sinclair AH, McGovern JD: Sry protein enhances transcription of fos-related antigen-1 promoter constructs. Proc Natl Acad Sci USA 1994, 91:4372-4376.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4372-4376
    • Cohen, D.R.1    Sinclair, A.H.2    McGovern, J.D.3
  • 31
    • 0028308118 scopus 로고
    • Nuclear receptor steroidogenic factor 1 regulates the Müllerian inhibiting substance gene: A link to the sex determination cascade
    • Shen WH, Moore CCD, Ikeda Y, Parker KL, Ingraham HA: Nuclear receptor steroidogenic factor 1 regulates the Müllerian inhibiting substance gene: a link to the sex determination cascade. Cell 1994, 77:651-661. This paper provides evidence that Sf1 is a direct activator of MIS expression. In vitro experiments show that Sf1 binds upstream regulatory elements in the MIS gene and, in the presence of a Sertoli cell specific co-factor, can trans-activate expression.
    • (1994) Cell , vol.77 , pp. 651-661
    • Shen, W.H.1    Moore, C.C.D.2    Ikeda, Y.3    Parker, K.L.4    Ingraham, H.A.5
  • 32
    • 0020048860 scopus 로고
    • Musposchiavinus Y-chromosome in the C57BL/6J murine genome causes sex reversal
    • Eicher EM, Washburn LL, Whitney JB, Morrow KE: Musposchiavinus Y-chromosome in the C57BL/6J murine genome causes sex reversal. Science 1982, 217:535-537.
    • (1982) Science , vol.217 , pp. 535-537
    • Eicher, E.M.1    Washburn, L.L.2    Whitney, J.B.3    Morrow, K.E.4
  • 33
    • 0028289482 scopus 로고
    • Polymorphism of a CAG trinucleotide repeat within Sry correlates with B6.Y(Dom) sex reversal
    • Coward P, Nagai K, Chen D, Thomas HD, Nagamine CM, Lau YFC: Polymorphism of a CAG trinucleotide repeat within Sry correlates with B6.Y(Dom) sex reversal. Nat Genet 1994, 6:245-250.
    • (1994) Nat Genet , vol.6 , pp. 245-250
    • Coward, P.1    Nagai, K.2    Chen, D.3    Thomas, H.D.4    Nagamine, C.M.5    Lau, Y.F.C.6
  • 34
    • 0028945899 scopus 로고
    • Sequence variation in the 5′, putative promoter of Sry and its possible relevance to the C57BL/6J Y(DOM) sex reversal
    • Graves PE, Erickson RP: Sequence variation in the 5′, putative promoter of Sry and its possible relevance to the C57BL/6J Y(DOM) sex reversal. Biochem Biophys Res Commun 1995, 208:624-628.
    • (1995) Biochem Biophys Res Commun , vol.208 , pp. 624-628
    • Graves, P.E.1    Erickson, R.P.2
  • 39
  • 41
    • 0028589588 scopus 로고
    • Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9
    • Wagner T, Wirth J, Meyer J, Zabel B, Held M, Zimmer J, Pasantes J, Dagna-Bricarelli F, Keutel J, Hustert E et al.: Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9. Cell 1994, 79:1111-1120. This study and [40••] describe translocation breakpoint mapping of sex-reversed CD patients. Mutation screening identified several heterozygous mutations of the SRY-related gene, SOX9, in both sex-reversed and non-sex-reversed CD individuals. This is evidence that CD s an autosomal dominant haplo-insufficiency syndrome and underlines the importance of gene dosage in sex-determining mechanisms.
    • (1994) Cell , vol.79 , pp. 1111-1120
    • Wagner, T.1    Wirth, J.2    Meyer, J.3    Zabel, B.4    Held, M.5    Zimmer, J.6    Pasantes, J.7    Dagna-Bricarelli, F.8    Keutel, J.9    Et Al, H.E.10
  • 42
    • 0028830855 scopus 로고
    • The Sry-related gene Sox-9 is expressed during chondrogenesis in mouse embryos
    • Wright E, Hargrave MR, Christiansen J, Cooper L, Kun J, Evans T, Gangadharan U, Greenfield A, Koopman P: The Sry-related gene Sox-9 is expressed during chondrogenesis in mouse embryos. Nat Genet 1995, 9:15-20. This paper describes the expression pattern of mouse Sox9 during embryogenesis, emphasizing its rote in skeletal development. Strong expression of Sox9 at sites of chondrogenesis mirror the sites of skeletal malformation seen in the human syndrome campomelic dysplasia.
    • (1995) Nat Genet , vol.9 , pp. 15-20
    • Wright, E.1    Hargrave, M.R.2    Christiansen, J.3    Cooper, L.4    Kun, J.5    Evans, T.6    Gangadharan, U.7    Greenfield, A.8    Koopman, P.9
  • 43
    • 0027295482 scopus 로고
    • Characterization of the mouse FTZ-F1 gene, which encodes a key regulator of steroid hydroxylases
    • Ikeda Y, Lala DS, Luo X, Kim E, Moisan M-P. Parker KL: Characterization of the mouse FTZ-F1 gene, which encodes a key regulator of steroid hydroxylases. Mol Endocrinol 1993, 7:852-860.
    • (1993) Mol Endocrinol , vol.7 , pp. 852-860
    • Ikeda, Y.1    Lala, D.S.2    Luo, X.3    Kim, E.4    Parker Kl, M.M.-P.5
  • 44
    • 0028276035 scopus 로고
    • Developmental expression of mouse steroidogenic factor 1, an essential regulator of the steroid hydroxylases
    • Ikeda Y, Shen W-H, Ingraham HA, Parker KL: Developmental expression of mouse steroidogenic factor 1, an essential regulator of the steroid hydroxylases. Mol Endocrinol 1994, 8:654-662.
    • (1994) Mol Endocrinol , vol.8 , pp. 654-662
    • Ikeda, Y.1    Shen, W.-H.2    Ingraham, H.A.3    Parker, K.L.4
  • 45
    • 0028303959 scopus 로고
    • A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation
    • Luo X, Ikeda Y, Parker KL: A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation. Cell 1994, 77:481-490. This mouse knockout experiment of Sf1, known to be required for steroid hormone biosynthesis, demonstrates that the gene is also required for the development and maintenance of both the adrenal glands and the indifferent gonad. Mice deficient for Sf1 lack adrenal glands and gonads. The dual role of Sf1 in early gonadal formation and later in hormone production was unexpected.
    • (1994) Cell , vol.77 , pp. 481-490
    • Luo, X.1    Ikeda, Y.2    Parker, K.L.3
  • 50
    • 0028181317 scopus 로고
    • WT1 mutations associated with incomplete Denys-Drash syndrome define a domain predicted to behave in a dominant-negative fashion
    • Bardeesy N, Zabel B, Schmitt K, Pelletier J: WT1 mutations associated with incomplete Denys-Drash syndrome define a domain predicted to behave in a dominant-negative fashion. Genomics 1994, 21:663-665.
    • (1994) Genomics , vol.21 , pp. 663-665
    • Bardeesy, N.1    Zabel, B.2    Schmitt, K.3    Pelletier, J.4
  • 54
    • 0018889219 scopus 로고
    • Abnormality of the X chromosome in human 46,XY female with dysgenetic ovaries
    • Bernstein R, Koo GC, Wachtel SS: Abnormality of the X chromosome in human 46,XY female with dysgenetic ovaries. Science 1980, 207:768-769.
    • (1980) Science , vol.207 , pp. 768-769
    • Bernstein, R.1    Koo, G.C.2    Wachtel, S.S.3
  • 55
    • 0028221672 scopus 로고
    • Testis determining gene(s) on the X chromosome short arm: Chromosomal localisation and possible role in testis determination
    • Ogata T, Matsuo N: Testis determining gene(s) on the X chromosome short arm: chromosomal localisation and possible role in testis determination. J Med Genet 1994, 31:349.
    • (1994) J Med Genet , vol.31 , pp. 349
    • Ogata, T.1    Matsuo, N.2
  • 57
    • 0028558750 scopus 로고
    • An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasla congenlta
    • Zanaria E, Muscatelli F, Bardoni B, Strom TM, Guioli S, Guo W, Lalli E, Moser C, Walker AP, McCabe ERB et al.: An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasla congenlta. Nature 1994, 372:635-641. This paper describes the cloning of DAX1 from the DSS-AHC critical region on the X. Mutations of DAX1 in AHC patients prove its identity as the adrenal hypoplasia congenita gene. DAXI is also a candidate for the X-linked dosage-sensitive sex-reversal gene and would encode a second nuclear hormone receptor (SF1 being the other) to be implicated in sex determination.
    • (1994) Nature , vol.372 , pp. 635-641
    • Zanaria, E.1    Muscatelli, F.2    Bardoni, B.3    Strom, T.M.4    Guioli, S.5    Guo, W.6    Lalli, E.7    Moser, C.8    Walker, A.P.9    Erb, M.10
  • 58
    • 0029912474 scopus 로고    scopus 로고
    • Mouse Dax1 expression is consistent with a role in sex determination as well as in adrenal and hypothalamus function
    • Swain A, Zanaria E, Hacker A, Lovell-Badge R, Camerino G: Mouse Dax1 expression is consistent with a role in sex determination as well as in adrenal and hypothalamus function. Nat Genet 1996, 12:404-409. This paper describes the cloning and expression anajysis of mouse Dax1 In addition to transcription in the developing adrenal glands and hypothalamus, sexually dimorphic expression is seen in the gonad. Dax1 is down-regulated with overt differentiation of the testis in males, but persists in the developing ovary, providing circumstantial evidence for Dax1 being equivalent to DSS.
    • (1996) Nat Genet , vol.12 , pp. 404-409
    • Swain, A.1    Zanaria, E.2    Hacker, A.3    Lovell-Badge, R.4    Camerino, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.