Calcitriol and the parathyroid hormone-ionized calcium curve: A comparison of methodologic approaches

Journal of the American Society of Nephrology

Volumn 7, Issue 3, 1996, Pages 497-505

  Ouseph, Rosemary ^a   Leiser, Jeffrey D ^a   Moe, Sharon M ^a,b  

^a INDIANA UNIVERSITY   (United States)

^b INDIANA UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Acidosis; Calcitriol; Hemodialysis; Parathyroid gland; Renal osteodystrophy; Set point

Indexed keywords

CALCITRIOL; CALCIUM ION; PARATHYROID HORMONE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; HEMODIALYSIS; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; METABOLIC ACIDOSIS; PARATHYROID GLAND; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RENAL OSTEODYSTROPHY;

EID: 0029942549     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Jara A, Bover J, Llach F: Treatment of secondary hyperparathyroidism in maintenance hemodialysis patients by intravenous calcitriol. Semin Dial 1994;7:117-123.
2. Lopez-Hilker S, Dusso AS, Rapp NS, Martin KJ, Slatopolsky E: Phosphorus restriction reverses hyperparathyroidism in uremia independent of changes in calcium and calcitriol. Am J Physiol 1990;259:F432-F437.
3. Coburn JW: Use of oral and parenteral calcitriol in the treatment of renal osteodystrophy. Kidney Int 1990;38: S54-S61.
4. Llach F, Massry SG, Singer FR, Kurokawa K, Kaye JM, Coburn JW: Skeletal resistance to endogenous parathyroid hormone in patients with early renal failure. A possible cause of secondary hyperparathyroidism. J Clin Endocrinol & Metab 1975;41:339-345.
5. Pitts TO, Piraino BH, Mitro R: Hyperparathyroidism and 1,25-dihydroxyvitamin D deficiency in mild, moderate, and severe renal failure. J Clin Endocrinol & Metab 1988;67:876-881.
6. Coe FL, Firpo JJ, Hollandsworth DL, Segil L, Canterbury JM, Reiss E: Effect of acute and chronic metabolic acidosis on serum immunoreactive parathyroid hormone in man. Kidney Int 1975;8:262-273.
7. Slatopolsky E, Weert SC, Thielan J, Horst R, Harter H, Martin KJ: Marked suppression of secondary hyperparathyroidism by intravenous administration of 1,25-dihydroxycholecalciferol in uremic patients. J Clin Invest 1984;74:2136-2143.
8. Silver J, Russel J, Sherwood LM: Regulation by vitamin D metabolites of messenger RNA for pre-parathyroid hormone in isolated bovine parathyroid cells. Proc Natl Acad Sci USA 1985;82:270-4273.
9. Dunlay R, Rodriguez M, Felsenfeld AJ, Llach F: Direct inhibitory effect of calcitriol on parathyroid function (sigmoidal curve) in dialysis. Kidney Int 1989;36:1093-1098.
10. Lefebvre A, De Vernejoul MC, Gueris J, Goldfarb B, Graulet AM, Morieux C: Optimal correction of acidosis changes progression of dialysis osteodystrophy. Kidney Int 1989;36:1112-1118.
11. Delmez JA, Tindira C, Grooms P, Dusso A, Windus DW, Slatopolsky E: Parathyroid hormone suppression by intravenous 1,25-Dihydroxyvitamin D. J Clin Invest 1989;83:1349-1355.
12. Brown EM, Wilson RE, Eastman RC, Pallotta J, Marynick SP: Abnormal regulation of parathyroid hormone release by calcium in secondary hyperparathyroidism due to chronic renal failure. J Clin Endocrinol & Metab 1982;54:172-179.
13. Brown EM: Four-parameter model of the sigmoidal relationship between parathyroid hormone release and extracellular calcium concentration in normal and abnormal parathyroid tissue. J Clin Endocrinol & Metab 1983; 56:572-581.
14. Delean A, Munson PJ, Rodbard D: Simultaneous analysis of sigmoidal curves: application to bioassay, radioligand assay and physiological dose-response curves. Am J Physiol 1978;235:E97-E102.
15. Ramirez JA, Goodman WG, Gornbein J, Menezes C, Moulton L, Segre GV, Salusky IB: Direct in vivo comparison of calcium-regulated parathyroid hormone secretion in normal volunteers and patients with secondary hyperparathyroidism. J Clin Endocrinol & Metab 1993; 76:1489-1494.
16. Ramirez JA, Goodman WG, Belin TR, Gales B, Segre GV, Salusky IB: Calcitriol therapy and calcium-regulated PTH secretion in patients with secondary hyperparathyroidism. Am J Physiol 1994;30:E961-E967.
17. Rodriguez M, Felsenfeld AJ, Williams C, Pederson JA, Llach F: The effect of long-term intravenous calcitriol administration on parathyroid function in hemodialysis patients. J Am Soc Nephrol 1991;2:1014-1020.
18. Malberti F, Surian M, Cosci P: Effect of chronic intravenous calcitriol on parathyroid function and set point of calcium in dialysis patients with refractory secondary hyperparathyroidism. Nephrol Dial Transplant 1992;7: 822-828.
19. Kwan JTC, Almond MK, Beer JC, Noonan K, Evans SJW, Cunningham J: 'Pulse' oral calcitriol in uremic patients: Rapid modification of parathyroid response to calcium. Nephrol Dial Transplant 1992;7:829-834.
20. Quarles LD, Yohay DA, Carroll BA, et al.: Prospective trial of pulse oral versus intravenous calcitriol treatment of hyperparathyroidism in ESRD. Kidney Int 1994;45: 1710-1721.
21. Caravaca F, Cubero JJ, Jimenez F, et al.: Effect of the mode of calcitriol administration on PTH-ionized calcium relationship in uraemic patients with secondary hyperparathyroidism. Nephrol Dial Transplant 1995;10:665-670.
22. Castleman B, Kibbee BU: Case records of the Massachusetts General Hospital: Case 1963;29. N Engl J Med 1963;268:943-953.
23. McCarron DA, Muther RS, Lenfesty B, Bennett WM: Parathyroid function in persistent hyperparathyroidism: Relationship to gland size. Kidney Int 1982;22:662-670.
24. Falchetti A, Bale AE, Amorosi A, et al.: Progression of uremic hyperparathyroidism involves allelic loss on chromosome 11. J Clin Endocrinol & Metab 1993;76-139-144.
25. Arnold A, Brown MF, Urena P, Gaz RD, Sarfati E, Drucke TB: Monoclonality of parathyroid tumors in chronic renal failure and in primary parathyroid hyperplasia. J Clin Invest 1995;95:2047-2053.
26. Messa P, Vallone C, Mioni G, et al.: Direct in vivo assessment of parathyroid hormone-calcium relationship curve in renal patients. Kidney Int 1994;46:1713-1720.
27. Combe C, Aparicio M: Phosphorus and protein restriction and parathyroid function in chronic renal failure Kidney Int 1994;46:1381-1386.
28. 3. Endocrinology 1995;136:499-504.