Selective brain cooling in infant piglets after cardiac arrest and resuscitation

Critical Care Medicine

Volumn 24, Issue 6, 1996, Pages 1009-1017

  Gelman, Barry ^a   Schleien, Charles L ^a   Lohe, Abhijit ^a   Kuluz, John W ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

blood flow, cerebral; cardiopulmonary resuscitation; cerebral ischemia; neurologic emergencies; pediatrics; reperfusion; temperature

Indexed keywords

OXYGEN;

ANIMAL MODEL; ARTICLE; BRAIN; BRAIN BLOOD FLOW; BRAIN METABOLISM; BRAIN OXYGEN CONSUMPTION; BRAIN TEMPERATURE; CONTROLLED STUDY; COOLING; CORE TEMPERATURE; HEART ARREST; HEMODYNAMICS; NONHUMAN; ORGAN BLOOD FLOW; PRIORITY JOURNAL; RESUSCITATION; SWINE;

ANIMALS; ANIMALS, NEWBORN; BODY TEMPERATURE; BRAIN; BRAIN ISCHEMIA; CARDIOPULMONARY RESUSCITATION; CEREBROVASCULAR CIRCULATION; HEART ARREST; HEMODYNAMIC PROCESSES; HYPOTHERMIA, INDUCED; OXYGEN CONSUMPTION; PROSPECTIVE STUDIES; REGIONAL BLOOD FLOW; REPERFUSION; SWINE;

EID: 0029941774     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-199606000-00022     Document Type: Article

References (60)

1. Busto R, Dietrich WD, Globus MYT, et al: Small differences in intraischemic brain temperature critically determine the extent of ischemic neuronal injury. J Cereb Blood Flow Metab 1987; 7: 729-738
2. Minamisawa H, Smith M-L, Siesjö BK: The effect of mild hyperthermia and hypothermia on brain damage following 5, 10, and 15 minutes of forebrain ischemia. Ann Neurol 1990; 28:26-33
3. Minamisawa H, Nordstrom CH, Smith ML, et al: The influence of mild body and brain hypothermia on ischemic brain damage. J Cereb Blood Flow Metab 1990; 10:365-374
4. Safar P: Resuscitation from clinical death: Pathophysiologic limits and therapeutic potentials. Crit Care Med 1988; 16:923-941
5. Hossmann KA: Resuscitation potentials after prolonged global cerebral ischemia in cats. Crit Care Med 1988; 16:964-971
6. Leonov Y, Sterz F, Safar P, et al: Mild cerebral hypothermia during and after cardiac arrest improves neurologic outcome in dogs. J Cereb Blood Flow Metab 1990; 10:57-70
7. Sterz F, Safar P, Tisherman S, et al: Mild hypothermic cardiopulmonary resuscitation improves outcome after prolonged cardiac arrest in dogs. Crit Care Med 1991; 19:379-389
8. Weinrauch V, Safar P, Tisherman S, et al: Beneficial effect of mild hypothermia and detrimental effect of deep hypothermia after cardiac arrest in dogs. Stroke 1992; 23:1454-1462
9. Busto R, Dietrich WD, Globus MYT, et al: Postischemic moderate hypothermia inhibits CA1 hippocampal ischemic neuronal injury. Neurosci Lett 1989; 101:299-304
10. Kuboyama K, Safar P, Radovsky, et al: Delay in cooling negates the beneficial effect of mild resuscitative cerebral hypothermia after cardiac arrest in dogs. Crit Care Med 1993; 21:1348-1358
11. Chopp M, Chen H, Dereski MO, et al: Mild hypothermic intervention after graded ischemic stress in rats. Stroke 1991; 22:37-43
12. Kuluz JW, Gregory GA, Yu ACH, et al: Selective brain cooling during and after prolonged global ischemia reduces cortical damage in rats. Stroke 1992; 23: 1792-1797
13. Kuluz JW, Prado R, Cheng J, et al: Selective brain cooling increases cortical cerebral blood flow in rats. Am J Physiol 1993; 265:H824-H827
14. Koehler RC, Chandra N, Guerci AD, et al: Augmentation of cerebral perfusion by simultaneous chest compression and lung inflation with abdominal binding after cardiac arrest in dogs. Circulation 1983; 67:266-275
15. Schleien CL, Dean JM, Koehler RC, et al: Effect of epinephrine on cerebral and myocardial perfusion in an infant animal preparation of cardiopulmonary resuscitation. Circulation 1986; 73: 809-817
16. Heymann MA, Payne BD, Hoffman JIE, et al: Blood flow measurements with radionuclide-labeled particles. Prog Cardiovas Dis 1977; 20:55-79
17. Dean JM, Koehler RC, Schleien CL, et al: Improved blood flow during prolonged cardiopulmonary resuscitation with 30% duty cycle in infant pigs. Circulation 1991; 84:896-904
18. Schleien CL, Koehler RC, Gervais H, et al: Organ blood flow and somatosensory-evoked potentials during and after cardiopulmonary resuscitation with epinephrine or phenylephrine. Circulation 1989; 79:1332-1342
19. Berkowitz ID, Gervais H, Schleien CL, et al: Epinephrine dosage effects on cerebral and myocardial blood flow in an infant swine model of cardiopulmonary resuscitation. Anesthesiology 1991; 75:1041-1050
20. Almond CH, Jones JC, Snyder HM, et al: Cooling gradients and brain damage with deep hypothermia. J Thorac Cardiovasc Surg 1964; 48:890-897
21. Busto R, Dietrich WD, Globus MYT, et al: The importance of brain temperature in cerebral ischemic injury. Stroke 1989; 20:1113-1114
22. Natale JE, D'Alecy LG: Protection from cerebral ischemia by brain cooling without reduced lactate accumulation in dogs. Stroke 1989; 20:770-777
23. Chater NA, Adams JE, Leake TB, et al: Cardiovascular effects of local brain stem cooling. Surg Forum 1960; 11:408-410
24. Senning A, Olsson PI: Changes in the vascular tonus during cerebral and regional hypothermia. Acta Chir Scand 1957; 112:209-220
25. Mellergard P: Changes in human intracerebral temperature in response to different methods of brain cooling. Neurosurgery 1992; 31:671-677
26. Horn M, Schlote W, Henrich HA: Global cerebral ischemia and subsequent selective hypothermia: A neuropathological and morphometrical study on ischemic neuronal damage in cat. Acta Neuropathol 1991; 81:443-449
27. Crowell N, Smith LR, Quill T, et al: The effect of temperature on cerebral metabolism and blood flow in adults during cardiopulmonary bypass. J Thorac Cardiovasc Surg 1992; 103:549-554
28. Dempsey RJ, Combs DJ, Maley ME, et al: Moderated hypothermia reduces post-ischemic edema development and leukotriene production. Neurosurgery 1987; 21:177-181
29. Busto R, Globus MYT, Dietrich WD, et al: Effect of mild hypothermia on ischemia-induced release of neurotransmitters and free fatty acids in rat brain. Stroke 1989; 20:904-910
30. Baiping L, Xiujuan T, Hongwei C, et al: Effect of moderate hypothermia on lipid peroxidation in canine brain tissue after cardiac arrest and resuscitation. Stroke 1994; 25:147-152
31. Clifton GL, Jiang JY, Lyeth BG, et al: Marked protection by moderate hypothermia after experimental traumatic brain injury. J Cereb Blood Flow Metab 1991; 11:114-121
32. Zhang RL, Chopp M, Chen H, et al: Postischemic (1 hour) hypothermia significantly reduces ischemic cell damage in rats subjected to 2 hours of middle cerebral artery occlusion. Stroke 1993; 24: 1235-1240
33. Coimbra C, Wieloch T: Hypothermia ameliorates neuronal survival when induced 2 hours after ischemia in the rat. Acta Physiol Scand 1992; 146:543-544
34. Maher J, Hachinski V: Hypothermia as a potential treatment for cerebral ischemia. Cerebrovasc Brain Metab Rev 1993; 5:277-300
35. Lee SK, Vaagenes P, Safar P, et al: Effect of cardiac arrest time on cortical cerebral blood flow during subsequent standard external cardiopulmonary resuscitation in rabbits. Resuscitation 1989; 17:105-117
36. Gervais HW, Schleien CL, Koehler RC, et al: Effect of adrenergic drugs on cerebral blood flow, metabolism, and evoked potentials after delayed cardiopulmonary resuscitation in dogs. Stroke 1991; 22:1554-1561
37. Snyder JV, Nemoto EM, Carroll RG, et al: Global ischemia in dogs: Intracranial pressures, brain blood flow and metabolism. Stroke 1975; 6:21-27
38. Lind B, Snyder J, Safar P: Total brain ischemia in dogs: Cerebral physiological and metabolic changes after 15 minutes of circulatory arrest. Resuscitation 1975; 4:97-113
39. Sterz R, Leonov Y, Safar P, et al: Multifocal cerebral blood flow by Xe-CT and global cerebral metabolism after prolonged cardiac arrest in dogs. Reperfusion with open-chest CPR or cardiopulmonary bypass. Resuscitation 1992; 24:27-47
40. Kirsch JR, Helfaer MA, Blizzard K, et al: Age-related cerebrovascular response to global ischemia in pigs. Am J Physiol 1990; 259:H1551-1558
41. Baldwin WA, Kirsch JR, Hurn PD, et al: Hypothermic cerebral reperfusion and recovery from ischemia. Am J Physiol 1991; 261:H774-H781
42. Ogura K, Takayasu M, Dacey RG Jr: Effects of hypothermia and hyperthermia on the reactivity of rat intracerebral arterioles in vitro. J Neurosurg 1991; 75:433-439
43. 2 and trimethophan camphorsulphonate (Arfonad). Acta Anaesthesiol Scand 1958; 2:149-163
44. Rosomoff HL, Holaday DA: Cerebral blood flow and cerebral oxygen consumption during hypothermia. Am J Physiol 1954; 179:85-88
45. Chopp M, Knight R, Tidwell CD, et al: The metabolic effects of mild hypothermia on global cerebral ischemia in the cat: Comparison to normothermia and hyperthermia. J Cereb Blood Flow Metab 1989; 9:141-148
46. Xue D, Huang ZG, Smith KE, et al: Immediate or delayed mild hypothermia prevents focal cerebral infarction. Brain Res 1992; 587:66-72
47. Todd MM, Warner DS: A comfortable hypothesis reevaluated: Cerebral metabolic depression and brain protection during ischemia. Anesthesiology 1992; 76:161-164
48. Sutton LN, Clark BJ, Norwood CR, et al: Global cerebral ischemia in piglets under conditions of mild and deep hypothermia. Stroke 1991; 22:1567-1573
49. Sano T, Drummond J, Patel P, et al: A comparison of the cerebral protective effects of isoflurane and mild hypothermia in a model of incomplete forebrain ischemia in the rat. Anesthesiology 1992; 76:221-228
50. Oku K, Sterz F, Safar P, et al: Mild hypothermia after cardiac arrest in dogs does not affect postarrest multifocal cerebral hypoperfusion. Stroke 1993; 24: 1590-1598
51. Kuboyama K, Safar P, Oku K, et al: Mild hypothermia after cardiac arrest in dogs does not affect postarrest cerebral oxygen uptake/delivery mismatching. Resuscitation 1994; 27:231-244
52. Mouritzen CV, Andersen MN: Myocardial temperature gradients and ventricular fibrillation during hypothermia. J Thorac Cardiovasc Surg 1965; 49: 937-944
53. Zarins CK, Skinner DB: Circulation in profound hypothermia. J Surg Res 1973; 14:97-104
54. Keykhah MM, Welsh FA, Hagerdal M, et al: Reduction of the cerebral protective effect of hypothermia by oligemic hypotension during hypoxia in the rat. Stroke 1982; 13:171-174
55. Hessel EA, Schmer G, Dillard DH: Platelet kinetics during deep hypothermia. J Surg Res 1980; 28:23-34
56. Mahajan SL, Myers TJ, Baldini MG: Disseminated intravascular coagulation during rewarming following hypothermia. JAMA 1981; 245:2517-2518
57. Biggar WD, Bohn D, Kent G: Neutrophil circulation and release from bone marrow during hypothermia. Infect Immun 1983; 40:708-712
58. Bohn DJ, Biggar WD, Smith CR, et al: Influence of hypothermia, barbiturate therapy, and intracranial pressure monitoring on morbidity and mortality after near-drowning. Crit Care Med 1986; 14:529-534
59. Juhasz-Nagy A, Kudasz J: The effect of selective cooling of the brain on cardiovascular dynamics. J Cardiovasc Surg 1971; 12:163-171
60. Anzia T, Turner MD, Gibson WH, et al: Blood flow distribution in dogs during hypothermia and posthypothermia. Am J Physiol 1978; 234:H706-H710