Non-adrenergic, non-cholinergic inhibitory junction potential in rat colonic circular muscle is partly sensitive to ω-conotoxin GVIA and resistant to L-, P-or Q-type calcium channel blockers

Neuroscience Letters

Volumn 210, Issue 2, 1996, Pages 91-94

  Borderies, J R ^a   Jimenez M ^b   Angel, F ^a  

^a INSERM   (France)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

Calcium; Gastrointestinal tract; Inhibitory junction potential; Non adrenergic non cholinergic transmission; Smooth muscle

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; NIFEDIPINE; OMEGA CONOTOXIN; VERAPAMIL;

ANIMAL TISSUE; ARTICLE; ELECTROSTIMULATION; INTESTINE MUSCLE; MALE; MICROELECTRODE; NEUROMUSCULAR SYNAPSE; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER MEMBRANE POTENTIAL; SYNAPTIC POTENTIAL; SYNAPTIC TRANSMISSION;

ADRENERGIC FIBERS; ANIMALS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CHOLINERGIC FIBERS; COLON; ELECTRIC STIMULATION; ELECTROPHYSIOLOGY; MALE; MEMBRANE POTENTIALS; MUSCLE, SMOOTH; NEUROMUSCULAR JUNCTION; NIFEDIPINE; OMEGA-AGATOXIN IVA; OMEGA-CONOTOXIN GVIA; PEPTIDES; RATS; RATS, WISTAR; SENSITIVITY AND SPECIFICITY; SPIDER VENOMS; TETRODOTOXIN; VERAPAMIL;

EID: 0029941686     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(96)12671-9     Document Type: Article

References (20)

1. Bridgewater, M., Cunnane, T.C. and Brading, A.F., Characteristic features of inhibitory junction potentials evoked by single stimuli in the guinea-pig isolated taenia caeci, J. Physiol., 485 (1995) 145-155.
2. De Luca, A., Rand, M.J., Reid, J.J., Thaina, P. and Wong-Dusting, H.K., Effects of ω-conotoxin GVIA on autonomic neuroeffector transmission in various tissues, Br. J. Pharmacol., 101 (1990) 437-447.
3. 2+ channels in mammalian central neurons, Trends Neurosci., 18 (1995) 89-98.
4. 2+ channels in neurotransmission in the rat urinary bladder, Br. J. Pharmacol., 116 (1995) 1595-1598.
5. Hess, P., Lansman, J.B. and Tsien, R.W., Different modes of Ca channel gating behaviour favoured by dihydropyridine Ca agonists and antagonists, Nature, 311 (1984) 538-544.
6. Holz, G.G., Dunlap, K. and Kream, R.M., Characterization of the electrically evoked release of substance P from dorsal root ganglion neurons: methods and dihydropyridine sensitivity, J. Neurosci., 8 (1988) 463-471.
7. Hong, S.J. and Chang, C.C., Inhibition of acetylcholine release from mouse motor nerve by a P-type calcium channel blocker, ω-agatoxin IVA, J. Physiol., 482 (1995) 283-290.
8. Jiménez, M. and Daniel, E.E., Effect of calcium channels blockers in the electrical activity of canine ileum, Gastroenterology, 104 (1993) A528.
9. Maggi, C.A., Patacchini, R., Santicioli, P., Lippe, I.Th., Giuliani, S., Geppetti, P., Del Bianco, E., Selleri, S. and Meli, A., The effect of omega conotoxin GVIA, a peptide modulator of the N-type voltage sensitive calcium channels, on motor responses produced by activation of efferent and sensory nerves in mammalian smooth muscle, Naunyn-Schmiedebergs Arch. Pharmacol., 338 (1988) 107-113.
10. Maggi, C.A., Patacchini, R., Santiciolo, P., Giuliani, S., Turini, D., Barbanti, G., Beneforti, P., Misuri, D. and Meli, A., Human isolated small intestine: motor responses of the longitudinal muscle to field stimulation and exogenous neuropeptides, Naunyn-Schmiedebergs Arch. Pharmacol., 339 (1989) 415-423.
11. Maggi, C.A., Holzer, P. and Giuliani, S., Effect of ω-conotoxin on cholinergic and tachykininergic excitatory neurotransmission to the circular muscle of the guinea-pig colon. Naunyn-Schmiedebergs Arch. Pharmacol., 350 (1994) 529-536.
12. Marino, F., Marcoli, M., De Ponti, F., Lecchini, S., Castelletti, C.M. and Frigo, G.M., Inhibition of endogenous acetylcholine release by blockade of voltage-dependent calcium channels in enteric neurons of the guinea-pig colon, J. Pharm. Pharmacol., 45 (1993) 449-452.
13. Mintz, I.M., Adams, M.E. and Bean, B.P., P-type calcium channels in rat central and peripheral neurons, Neuron, 9 (1992) 85-95.
14. Seabrook, G.R. and Adams, D.J., Inhibition of neurally-evoked transmitter release by calcium channel antagonists in rat parasympathetic ganglia, Br. J. Pharmacol., 97 (1989) 1125-1136.
15. Serio, R., Mulè, F. and Postorino, A., Non-adrenergic, non-cholinergic inhibitory responses to nerve stimulation in rat colonic circular muscle, Exp. Physiol., 77 (1992) 119-127.
16. Serio, R., Mulè, F. and Postorino, A., Nonadrenergic, noncholinergic inhibitory junction potentials in rat proximal colon: role of nitric oxide, Can. J. Physiol. Pharmacol., 73 (1995) 79-84.
17. 45Ca entry to ω-conotoxin, Biochem. Biophys. Res. Commun., 145 (1987) 1283-1286.
18. Suthamnatpong, N., Hosokawa, M., Takeuchi, T, Hata, F. and Takewaki, T., Nitric oxide-mediated inhibitory response of rat proximal colon: independence from changes in membrane potential, Br. J. Pharmacol., 112 (1994) 676-682.
19. 3H]acetylcholine from the myenteric plexus, phrenic nerve and neocortex of rats, Naunyn-Schmiedebergs Arch. Pharmacol., 341 (1990) 288-294.
20. 2+ channels in supporting hippocampal synaptic transmission, Science, 264 (1994) 107-111.