The Garrod lecture: Evasion of antibiotic action by bacteria

Journal of Antimicrobial Chemotherapy

Volumn 37, Issue 5, 1996, Pages 855-869

  Courvalin, P ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT;

ANTIBIOTIC RESISTANCE; ANTIMICROBIAL ACTIVITY; BACTERIAL GENE; BACTERIUM CONJUGATION; GENE EXPRESSION REGULATION; GENE MUTATION; GENE TRANSFER; GENETIC TRANSFORMATION; INFECTION; MORTALITY; NONHUMAN; PLASMID; REVIEW;

ANTI-BACTERIAL AGENTS; CHROMOSOMES; DRUG RESISTANCE, MICROBIAL; EVOLUTION; GENE TRANSFER TECHNIQUES; HUMANS; MODELS, GENETIC; MUTATION; SELECTION (GENETICS); TRANSCRIPTION, GENETIC; TRANSFORMATION, GENETIC;

EID: 0029941579     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/37.5.855     Document Type: Article

References (79)

1. Allignet J., Aubert, S., Morvan, A. & El Solh, N. (1996). Distribution of the genes encoding resistance to streptogramin A among staphylococci resistant to this antibiotic. Submitted for publication.
2. Andremont, A., Raibaud, P. & Tancrède, C. (1983). Effect of erythromycin on microbial antagonisms: a study in gnotobiotic mice associated with a human fecal flora. Journal of Infectious Diseases 148, 579-87.
3. Andremont, A., Sancho-Garnier, H. & Tancrède, C. (1986). Epidemiology of intestinal colonization by members of the family Enterobacteriaceae highly resistant to erythromycin in a hematology-oncology unit. Antimicrobial Agents and Chemotherapy 29, 1104-7.
4. Andremont, A. & Tancrède, C. (1981). Reduction of the aerobic Gram-negative bacterial flora of the gastro-intestinal tract and prevention of traveller's diarrhea using oral erythromycin. Annales de Microbiologie/Institut Pasteur (Paris) 132B, 419-27.
5. Arthur, M. & Courvalin, P. (1986). Contribution of two different mechanisms to erythromycin resistance in Escherichia coli. Antimicrobial Agents and Chemotherapy 30, 694-700.
6. Arthur, M. & Courvalin, P. (1993). Genetics and mechanisms of glycopeptide resistance in enterococci. Antimicrobial Agents and Chemotherapy 37, 1563-71.
7. Arthur, M., Molinas, C. & Courvalin, P. (1992) The VanS-VanR two-component regulatory system controls synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147. Journal of Bacteriology 174, 2582-91.
8. Arthur, M., Molinas, C., Depardieu, F. & Courvalin, P. (1993). Characterization of Tn1546, a Tn3-related transposon conferring glycopeptide resistance by synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147. Journal of Bacteriology 175, 117-27.
9. Bauernfeind, A., Chong, Y. & Schweighart, S. (1989). Extended broad spectrum β-lactamase in Klebsiella pneumoniae including resistance to cephamycins. Infection 17, 316-21.
10. Bauernfeind, A., Schweighart, S., Dornbusch, K. & Giamarellou, H. (1990). A transferable cephamycinase (CMY-ase) in Klebsiella pneumoniae (K. pn.). In Program and Abstracts of the Thirtieth Interscience Conference on Antimicrobial Agents and Chemotherapy, Atlanta, GA, 1990. Abstract 190. American Society for Microbiology, Washington, DC.
11. Berg, D. E. & Howe, M. M. (1989). Mobile DNA. American Society for Microbiology, Washington, DC.
12. Billot-Klein, D., Gutmann, L., Sable, S., Guittet, E. & van Heijenoort, J. (1994). Modification of peptidoglycan precursors is a common feature of the low-level vancomycin-resistant VanB-type Enterococcus D366 and of the naturally glycopeptide-resistant species Lactobacillus casei, Pediococcus pentosaceus, Leuconostoc mesenteroides, and Enterococcus gallinarum. Journal of Bacteriology 176, 2398-405.
13. Bismuth, R., Zilhao, R., Sakamoto, H., Guesdon, J. L. & Courvalin, P. (1990). Gene heterogeneity for tetracycline resistance in Staphylococcus spp. Antimicrobial Agents and Chemotherapy 34, 1611-4.
14. Brisson-Noël, A., Arthur, M. & Courvalin, P. (1988). Evidence for natural gene transfer from Gram-positive cocci to Escherichia coli. Journal of Bacteriology 170, 1739-45.
15. Bush, K. (1989). Characterization of β-lactamases. Antimicrobial Agents and Chemotherapy 33, 259-63.
16. Charpentier, E. & Courvalin, P. (1995). Resistance aux antibiotiques chez Listeria spp. Médecine et Maladies Infectieuses 255, 225-32.
17. Clewell, D. B. & Flannagan, S. E. (1993). The conjugative transposons of Gram-positive bacteria. In Bacterial conjugation (Clewell, D. B., Ed.), pp. 369-93. Plenum Press, New York.
18. Courvalin, P. (1994). Transfer of antibiotic resistance genes between Gram-positive and Gram-negative bacteria. Antimicrobial Agents and Chemotherapy 38, 1447-51.
19. Courvalin, P. & Carlier, C. (1986). Transposable multiple antibiotic resistance in Streptococcus pneumoniae. Molecular and General Genetics 205, 291-7.
20. Davies, J. (1994). Inactivation of antibiotics and the dissemination of resistance genes. Science 264, 375-82.
21. Doucet-Populaire, F., Trieu-Cuot, P., Andremont, A. & Courvalin, P. (1992). Conjugal transfer of plasmid DNA from Enterococcus faecalis to Escherichia coli in digestive tracts of gnotobiotic mice. Antimicrobial Agents and Chemotherapy 36, 502-4.
22. Dutka-Malen, S., Evers, S. & Courvalin, P. (1995). Detection of glycopeptide resistance genotypes and identification to the species level of clinically relevant enterococci by PCR. Journal of Clinical Microbiology 33, 24-7.
23. B two-component regulatory system in Enterococcus faecalis V583. Journal of Bacteriology 178, 1302-9.
24. Ferretti, J. J., Gilmore, K. S. & Courvalin, P. (1986). Nucleotide sequence analysis of the bifunctional 6′-aminoglycoside acetyltransferase, 2″-aminoglycoside phosphotransferase determinant from Streptococcus faecalis: identification and cloning of gene regions specifying the two activities. Journal of Bacteriology 167, 631-8.
25. Gormley, E. P. & Davies, J. (1991). Transfer of plasmid RSF1010 by conjugation from Escherichia coli to Streptomyces lividans and Mycobacterium smegmatis. Journal of Bacteriology 173, 6705-8.
26. Goussard, S., Sougakoff, W., Mabilat, C., Bauernfeind, A. & Courvalin, P. (1991). An IS1-like element is responsible for high-level synthesis of extended-spectrum β-lactamase TEM-6 in Enterobacteriaceae. Journal of General Microbiology 137, 2681-7.
27. Goze, A. & Ehrlich, S. D. (1980). Replication of plasmids from Staphylococcus aureus in Escherichia coli. Proceedings of the National Academy of Sciences, USA 77, 7333-7.
28. Green, M., Shlaes, J. H., Barbadora, K. & Shlaes, D. M. (1995). Bacteremia due to vancomycin-dependent Enterococcus faecium. Clinical Infectious Diseases 20, 712-4.
29. Gutmann, L., Billot-Klein, D., Al-Obeid, S., Klare, I., Francoual, S., Collatz, E. & Van Heijenoort, J. (1992). Inducible carboxypeptidase activity in vancomycin-resistant enterococci. Antimicrobial Agents and Chemotherapy 36, 77-80.
30. Hall, R. M. & Collis, C. M. (1995). Mobile gene cassettes and integrons: capture and spread of genes by site-specific recombination. Molecular Microbiology 15, 593-600.
31. Hall, R. M. & Stokes, H. W. (1993). Integrons: novel DNA elements which capture genes by site-specific recombination. Genetica 90, 115-32.
32. Hayden, M. K., Trenholme, G. M., Schultz, J. E. & Sahm, D. F. (1993). In vivo development of teicoplanin resistance in a VanB Enterococcus faecium. Journal of Infectious Diseases 167, 1224-7.
33. Higgins, C. F. (1995). The ABC of channel regulation. Cell 82, 693-6.
34. Hoch, J. A. & Silhavy, T. J. (1995). Two-component signal transduction. American Society for Microbiology, Washington DC.
35. Labigne-Roussel, A., Briaux-Gerbaud, S. & Couvalin, P. (1983). Tn1525, a kanamycin R determinant flanked by two direct copies of IS15. Molecular and General Genetics 189, 90-101.
36. Lambert, T., Gerbaud, G., Trieu-Cuot, P. & Courvalin, P. (1985). Structural relationship between the genes encoding 3′-aminoglycoside phosphotransferases in Campylobacter and in Gram-positive cocci. Annales de Microbiologie/Institut Pasteur (Paris). 136B, 135-50.
37. Le Bouguénec, C., de Cespédès, G. & Horaud, T. (1988). Molecular analysis of a composite chromosomal conjugative element (Tn3701) of Streptococcus pyogenes. Journal of Bacteriology 170, 3930-6.
38. Leclercq, R. & Courvalin, P. (1991a). Bacterial resistance to macrolide, lincosamide and streptogramin antibiotics by target modification. Antimicrobial Agents and Chemotherapy 35, 1267-72.
39. Leclercq, R. & Courvalin, P. (1991b). Intrinsic and unusual resistance to macrolide, lincosamide, and streptogramin antibiotics in bacteria. Antimicrobial Agents and Chemotherapy 35, 1273-6.
40. Leclercq, R., Derlot, E., Duval, J. & Courvalin, P. (1988). Plasmid-mediated resistance to vancomycin and teicoplanin in Enterococcus faecium. New England Journal of Medicine 319, 157-61.
41. Leclercq, R., Dutka-Malen, S., Brisson-Noël, A., Molinas, C., Derlot, E., Arthur, M., Duval, J. & Courvalin, P. (1992). Resistance of enterococci to aminoglycosides and glycopeptides. Clinical Infectious Diseases 15, 495-501.
42. Lovett, P. S. (1994). Nascent peptide regulation of translation. Journal of Bacteriology 21, 6415-7.
43. Mabilat, C. & Courvalin, P. (1990). Development of "Oligotyping" for characterization and molecular epidemiology of TEM β-lactamases in members of the family Enterobacteriaceae. Antimicrobial Agents and Chemotherapy 34, 2210-6.
44. Mabilat, C., Lourençao-Vital, J., Goussard, S. & Courvalin, P. (1992). A new example of physical linkage between Tn1 and Tn21: the antibiotic multiple-resistance region of plasmid pCFF04 encoding extended-spectrum β-lactamase TEM-3. Molecular and General Genetics 235, 113-21.
45. Mazodier, P. & Davies, J. (1991). Gene transfer between distantly related bacteria. Annual Review of Genetics 25, 147-71.
46. Mazodier, P., Giraud, E. & Gasser, F. (1983). Genetic analysis of the streptomycin resistance encoded by Tn5. Molecular and General Genetics 192, 155-62.
47. Muto, A. & Osawa, S. (1987). The guanine plus cytosine content of genomic DNA and bacterial evolution. Proceedings of the National Academy of Sciences, USA 84, 166-9.
48. Neu, H. C. (1992). The crisis in antibiotic resistance. Science 257, 1064-72.
49. Nikaïdo, H. (1994). Prevention of drug access to bacterial targets: role of permeability barriers and active efflux. Science 264, 382-8.
50. Noble, W. C. Virani, Z. & Cree, R. G. A. (1992), Co-transfer of vancomycin and other resistance genes from Enterococcus faecalis NCTC 12201 to Staphylococcus aureus. FEMS Microbiology Letters 93, 195-8.
51. Ounissi, H., Derlot, E., Carlier, C. & Courvalin, P. (1990). Gene homogeneity for aminoglycoside-modifying enzymes in gram-positive cocci. Antimicrobial Agents and Chemotherapy 34, 2164-8.
52. Papanicolaou, G. A., Medeiros, A. A. & Jacoby, G. A. (1990). Novel plasmid-mediated β-lactamase (MIR-1) conferring resistance to oxyimino- and a-methoxy β-lactams in clinical isolates of Klebsiella pneumoniae. Antimicrobial Agents and Chemotherapy 34, 2200-9.
53. Pernodet, J.-L., Simonet, J.-M. & Guérineau, M. (1984). Plasmids in different strains of Streptomyces ambofaciens: free and integrated form of plasmid pSAM2. Molecular and General Genetics 198, 35-41.
54. Ploy, M. C., Giamarellou, H., Bourlioux, P., Courvalin, P. & Lambert, T. (1994). Detection of aac(6′)-I genes in amikacin resistant Acinetobacter spp. by PCR. Antimicrobial Agents and Chemotherapy 38, 2925-8.
55. Podglajen, I., Breuil, J. & Collatz, E. (1994). Insertion of a novel DNA sequence, IS1186, upstream of the silent carbapenemase gene cfiA, promotes expression of carbapenem resistance in clinical isolates of Bacteroides fragilis. Molecular Microbiology 12, 105-14.
56. Poole, K. (1994). Bacterial multidrug resistance-emphasis on efflux mechanisms and Pseudomonas aeruginosa. Journal of Antimicrobial Chemotherapy 34, 453-6.
57. Poyart, C., Celli, J. & Trieu-Cuot, P. (1995). Conjugative transposition of Tn916-related elements from Enterococcus faecalis to Escherichia coli and Pseudomonas fluorescens. Antimicrobial Agents and Chemotherapy 39, 500-6.
58. Poyart-Salmeron, C., Carlier, C., Trieu-Cuot, P., Courtieu, A. & Courvalin, P. (1990). Transferable plasmid-mediated antibiotic resistance in Listeria monocytogenes. Lancet 335, 1422-6.
59. Poyart-Salmeron, C., Trieu-Cuot, P., Carlier, C. & Courvalin, P. (1989). Molecular characterization of two proteins involved in the excision of the conjugative transposon Tn1545: Homologies with other site-specific recombinases. EMBO Journal 8, 2425-33.
60. Poyart-Salmeron, C., Trieu-Cuot, P., Carlier, C., McGowan, A., McLauchlin, J. & Courvalin, P. (1992). Genetic basis of tetracycline resistance in clinical isolates of Listeria monocytogenes. Antimicrobial Agents and Chemotherapy 36, 463-6.
61. Privitera, G., Sebald, M. & Fayolle, F. (1979). A common regulatory mechanism for expression and conjugative ability of a tetracycline plasmid in Bacteroides fragilis. Nature 278, 657-9.
62. Quentin, C., Thibaut, M. C., Horovitz, J. & Bebear, C. (1990). Multiresistant strain of Listeria monocytogenes in septic abortion. Lancet 336, 375.
63. Rather, P. N., Orosz, E., Shaw, K. J., Hare, R. & Miller, G. (1993). Characterization and transcriptional regulation of the 2′-N-acetyltransferase gene from Providencia stuartii. Journal of Bacteriology 175, 6492-8.
64. Reynolds, P. E., Snaith, H. A., Maguire, A. J., Dutka-Malen, S. & Courvalin, P. (1994). Analysis of peptidoglycan precursors in vancomycin resistant Enterococcus gallinarum BM4174. Biochemistry Journal 301, 5-8.
65. Rogers, E. J., Ambulos, N. P. & Lovett, P. S. (1990). Complementarity of Bacillus subtilis 16S rRNA with sites of antibiotic-dependent ribosome stalling in cat and erm leaders. Journal of Bacteriology 172, 6282-90,
66. Rosato, A., Pierre, J., Billot-Klein, D., Buu-Hoi, A., & Gutmann, L. (1995). Inducible and constitutive expression of resistance to glycopeptides and vancomycin dependence in glycopeptide-resistant Enterococcus avium. Antimicrobial Agents and Chemotherapy 39, 830-3.
67. Ross, J. I., Eady, E. A., Cove J. H. & Baumberg, S. (1995). Identification of a chromosomally encoded ABC-transport system with which the staphylococcal erythromycin exporter MsrA may interact. Gene 153, 93-8.
68. Ross, J. I., Eady, E. A., Cove, J. H., Cunliffe, W. J., Baumberg, S. & Wootton, J. C. (1990). Inducible erythromycin resistance in staphylococci is encoded by a member of the ATP-binding transport super-gene family. Molecular Microbiology 4, 1207-14.
69. Rowland, S. J. & Dyke, K. G. H. (1990). Tn552, a novel transposable element from Staphylococcus aureus. Molecular Microbiology 4, 961-75.
70. Rudant, E., Bourlioux, P., Courvalin, P. & Lambert, T. (1994). Characterization of the aac(6′)-Ik gene of Acinetobacter sp. 6 FEMS Microbiology Letters 124, 49-54.
71. Sougakoff, W., Goussard, S., Gerbaud, G. & Courvalin, P. (1988). Plasmid-mediated resistance to third-generation cephalosporins caused by point-mutations in TEM-type penicillinase genes. Reviews of Infectious Diseases 10, 879-84.
72. Speer, B. S. & Salyers, A. A. (1989). Novel aerobic tetracycline resistance gene that chemically modifies tetracycline. Journal of Bacteriology 171, 148-53.
73. Spratt, B. G., Bowler, L. D., Zhang, Q.-Y., Zhou, J. & Smith, J. M. (1992). Role of interspecies transfer of chromosomal genes in the evolution of penicillin resistance in pathogenic and commensal Neisseria species. Journal of Molecular Evolution 34, 115-25.
74. Syvanen, M. (1994). Horizontal gene transfer: evidence and possible consequences. Annual Review of Genetics 28, 237-61.
75. Tietze, E. & Brevet, J. (1991). The trimethoprim resistance transposon Tn7 contains a cryptic streptothricin resistance gene. Plasmid 25, 217-20.
76. Tomich, P. K., An F. Y. & Clewell, D. B. (1980). Properties of erythromycin-inducible transposon Tn917 in Streptococcus faecalis. Journal of Bacteriology 141, 1366-74.
77. Trieu-Cuot, P., Derlot, E. & Courvalin, P. (1993). Enhanced conjugative transfer of plasmid DNA from Escherichia coli to Staphylococcus aureus and Listeria monocytogenes. FEMS Microbiology Letters 109, 19-24.
78. Webb, V. & Davies, J. (1993). Antibiotic preparations contain DNA: a source of drug resistance genes? Antimicrobial Agents and Chemotherapy 11, 2379-84.
79. Zilhao, R., Papadopoulou, B. & Courvalin, P. (1988). Occurence of the Campylobacter resistance gene tetO in Enterococcus and Streptococcus spp. Antimicrobial Agents and Chemotherapy 32, 1793-6.