The ATP-binding site in the 2-kinase domain of liver 6-phosphofructo-2- kinase/fructose-2,6-bisphosphatase. Study of the role of Lys-54 and Thr-55 by site-directed mutagenesis

Journal of Biological Chemistry

Volumn 271, Issue 30, 1996, Pages 17875-17880

  Vertommen, Didier ^a   Bertrand, Luc ^a   Sontag, Bruno ^b   Di Pietro, Attilio ^b   Louckx, Marc P ^a   Vidal, Hubert ^c   Hue, Louis ^a   Rider, Mark H ^a,d  

^a International Institute of Cellular and Molecular Pathology   (Belgium)

^b INSTITUT DE BIOLOGIE ET CHIMIE DES PROTÉINES   (France)

^c INSERM   (France)

^d UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

6 PHOSPHOFRUCTO 2 KINASE; ADENOSINE TRIPHOSPHATE; FRUCTOSE 2,6 BISPHOSPHATASE;

ARTICLE; BINDING SITE; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME PHOSPHORYLATION; LIVER PARENCHYMA; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANIMALS; ANTHRANILIC ACIDS; BASE SEQUENCE; BINDING SITES; CIRCULAR DICHROISM; ISOENZYMES; KINETICS; LIVER; LYSINE; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; MUTAGENESIS, SITE-DIRECTED; PHOSPHOFRUCTOKINASE-2; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); RATS; RECOMBINANT PROTEINS; THREONINE;

EID: 0029941304     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.30.17875     Document Type: Article

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