Development and characterization of a novel monoclonal antibody (mNI-11) that induces cell adhesion of the lps-stimulated human monocyte-like cell line U937

Journal of Leukocyte Biology

Volumn 59, Issue 5, 1996, Pages 697-708

  Ikewaki, Nobunao ^a   Inoko, Hidetoshi ^b  

^a KITASATO UNIVERSITY   (Japan)

^b TOKAI UNIVERSITY   (Japan)

Author keywords

CD14+ cells; human umbilical vein endothelial cells; ICAM 1; LFA 1

Indexed keywords

CD14 ANTIGEN; GENISTEIN; INTERCELLULAR ADHESION MOLECULE 1; LIPOPOLYSACCHARIDE; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY MNI 11; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ANTIGEN RECOGNITION; ARTICLE; CELL ADHESION; CELL AGGREGATION; CELL STIMULATION; CROSS LINKING; ENDOTHELIUM CELL; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; MONOCYTE; PRIORITY JOURNAL; UMBILICAL VEIN;

EID: 0029941197     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlb.59.5.697     Document Type: Article

References (58)

1. Patarroyo, M., Prieto, J., Rincon, J., Timonen, T., Lundberg, C., Lindbom, L., Asjo, B., Gahmberg, C. G. (1990) Leukocyte-cell adhesion: A molecular process fundamental in leukocyte physiology. Immunol. Rev. 114, 67-107.
2. Arnaout, M. A. (1990) Leukocyte adhesion molecule deficiency: Its structural basis, pathophysiology and implications for modulating the inflammatory response. Immunol. Rev. 114, 145-180.
3. Keizer, G. D., Visser, W., Vliem, M., Figdor, C. G. (1988) A monoclonal antibody (NKI-L16) directed against a unique epitope on the α-chain of human leukocyte function-associated antigen 1 induces homotypic cell-cell interactions. J. Immunol. 140, 1393-1400.
4. Lauener, R. P., Geha, R. S., Vercelli, D. (1990) Engagement of the monocyte surface antigen CD14 induces lymphocyte function-associated antigen-1/intercellular adhesion molecule-1-dependent homotypic adhesion. J. Immunol. 145, 1390-1394.
5. Robinson, M. K., Andrew, D., Rosen, H., Brown, D., Ortlepp, S., Stephens, P., Butcher, E. C. (1992) Antibody against the Leu-CAM β chain (CD18) promotes both LFA-1-and CR3-dependent adhesion events. J. Immunol. 148, 1080-1085.
6. Traore, Y., Hirn, J. (1994) Certain anti-CD34 monoclonal antibodies induce homotypic adhesion of leukemic cell line in a CD18-dependent and a CD18-independent way. Eur. J. Immunol. 24, 2304-2311.
7. Barrett, T. B., Shu, G., Clark, E. A. (1991) CD40 signaling activates CD11a/CD18 (LFA-1)-mediated adhesion in B cells. J. Immunol. 146, 1722-1729.
8. Nong, Y-H., O'Donnell, R., Lebien, T. W., Remold, H. G. (1989) A monoclonal antibody to sialophorin (CD43) induces homotypic adhesion and activation of human monocytes. J. Exp. Med. 170, 259-267.
9. Wayner, E. A., Carter, W. G. (1987) Identification of multiple cell-adhesion receptors for collagen and fibronectin in human fibrosarcoma cells possessing unique α-and common β-subunits. J. Cell Biol. 105, 1873-1884.
10. Lorenz, H. M., Harter, T., Lagoo, A. S., Baur, A., Eger, G., Kalden, J. R. (1993) CD45 mAb induces cell adhesion in peripheral blood mononuclear cells via lymphocyte function-associated antigen-1 (LFA-1) and intercellular cell adhesion molecule 1 (ICAM-1). Cell. Immunol. 147, 110-128.
11. Spertini, F., Wang, A. V. T., Chatila, T., Geha, R. S. (1994) Engagement of the common leukocyte antigen CD45 induces homotypic adhesion of activated human T cells. J. Immunol. 153, 1593-1602.
12. Cid, M. C., Esparza, J., Juan, M., Miralles, A., Ordi, J., Vilella, R., Urbano-Marquez, A., Gaya, A., Vives, J., Yague, J. (1994) Signaling through CD50 (ICAM-3) stimulates T lymphocyte binding to human umbilical vein endothelial cells and extracellular matrix proteins via an increase in β1 and β2 integrin function. Eur. J. Immunol. 24, 1377-1382.
13. Spertini, F., Chatila, T., Geha, R. S. (1992) Engagement of MHC class I molecules induces cell adhesion via both LFA-1-dependent and LFA-1-independent pathways. J. Immunol. 148, 2045-2049.
14. Mourad, W., Geha, R. S., Chatila, T. (1990) Engagement of major histocompatibility complex class II molecules induces sustained lymphocyte function-associated molecule-1 dependent cell adhesion. J. Exp. Med. 172, 1513-1516.
15. Odum, N., Yoshizumi, H., Okamoto, Y., Kamikawaji, N., Kimura, A., Nishimura, Y., Sasazuki, T. (1992) Signal transduction by HLA class II molecule in human T cells: Induction of LFA-1-dependent and independent. Human Immunol. 35, 71-84.
16. DiCorleto, P. E., de la Motte, C. A. (1985) Characterization of the adhesion of the human monocytic cell line U937 to cultured endothelial cells. J. Clin. Invest. 75, 1153-1161.
17. Cavender, D. E., Edelbaum, D., Welkovich, L. (1991) Effects of inflammatory cytokines and phorbol esters on the adhesion of U937 cells, a human monocyte-like cell line, to endothelial cell monolayers and extracellular matrix proteins. J. Leukoc. Biol. 49, 566-578.
18. Ikewaki, N., Inoko, H. (1991) Induction of CD14 antigen on the surface of U937 cells by an interleukin-6 autocrine mechanism after cultures with formalin-killed Gram-negative bacteria. Tissue Antigens 38, 117-123.
19. Ikewaki, N., Tamauchi, H., Inoko, H. (1993) Modulation of cell surface antigens and regulation of phagocytic activity mediated by CD11b in the monocyte-like cell line U937 in response to lipopolysaccharide. Tissue Antigens 42, 125-132.
20. Inghirami, G., Wieczorek, R., Zhu, B-Y., Silber, R., Dalla-Favera, R., Knowles, D. M. (1988) Differential expression of LFA-1 molecules in non-Hodgkin's lymphoma and lymphoid leukemia. Blood 72, 1431-1434.
21. + cells that suppresses T cell proliferative response. J. Immunol. 131, 2757-2761.
22. Lanierr, L. L., Arnaout, M. A., Schwarting, R., Warner, N. L., Ross, G. D. (1985) p150/95, third membrane of the LFA-1/CR3 polypeptide family identified by anti-Leu-M5 monoclonal antibody. Eur. J. Immunol. 15, 713-718.
23. Mentzer, S. J., Faller, D. V., Burakoff, S. J. (1986) Interferon-γ induction of LFA-1 mediated homotypic adhesion of human monocytes. J. Immunol. 137, 108-113.
24. Selvaraj, P., Plunkett, M. L., Dustin, M., Sanders, M. E., Show, S., Springer, T. A. (1987) The T-lymphocyte glycoprotein CD2 binds the cell-surface ligand LFA-3. Nature 326, 400-403.
25. Patarroyo, M., Clark, E. A., Prieto, J., Kantor, C., Gahmberg, C. G. (1987) Identification of a novel adhesion molecule in human leukocytes by monoclonal antibody LB-2. FEBS Lett. 210, 127-131.
26. Shimizu, Y., Van Seventer, G. A., Siraganian, R., Wahl, L., Show, S. (1989) Dual role of the CD44 molecule in T cell adhesion and activation. J. Immunol. 143, 2457-2463.
27. Perussia, B., Trinchieri, G., Jackson, A., Warner, N. L., Faist, J., Rumpold, H., Kraft, P., Lanier, L. L. (1984) The Fc receptor for IgG on human natural killer cells: Phenotypic, functional, and comparative studies with monoclonal antibodies. J. Immunol. 33, 180-189.
28. Strickerler, J. G., Wiess, L. M., Copenhaver, C. M., Bindl, J. M., McDaid, R., Buck, D., Warnke, R. (1987) Monoclonal antibodies reactive in routinely processed tissue sections of malignant lymphoma, with emphasis on T cell lymphomas. Human Pathol. 18, 808-814.
29. Albelda, S. M., Muller, W. A., Buck, C. A., Newman, P. J. (1991) Molecular and cellular properties of PECAM-1 (endo CAM/CD31): A novel vasucular cell-cell adhesion molecule. J. Cell Biol. 114, 1059-1068.
30. McIntyre, B. W., Evans, E. L., Bednarczyk, J. L. (1989) Lymphocyte surface antigen L25 is a member of the integrin receptor superfamily. J. Biol. Chem. 264, 13745-13750.
31. Ennis, E., Isberg, R. R., Shimizu, Y. (1993) Very late antigen 4-dependent adhesion and costimulation of resting human T cells by the bacterial β1 integrin ligand invasion. J. Exp. Med. 177, 207-212.
32. Kan, E. A. R., Wang, C. Y., Wang, L. C., Evans, R. L. (1983) Non-covalently bonded subunits of 22 and 28 kd are rapidly internalized by T cells reacted with anti- Leu-4 antibody. J. Immunol. 131, 536-539.
33. Loken, M. R., Shah, V. O., Dattilio, K. L., Civin, C. I. (1987) Flow cytometric analysis of human bone marrow. II. Normal B lymphocyte development. Blood 70, 1316-1324.
34. Dimitriu-Bona, A., Burmester, G. R., Waters, S. J., Winchester, R. J. (1983) Human mononuclear phagocyte differentiation antigens. I. Pattern of antigenic expression on the surface of human monocytes and macrophages defined by monoclonal antibodies. J. Immunol. 130, 145-152.
35. Hercend, T., Griffin, J. D., Benussan, A., Schmidt, R. E., Edson, M. A., Brennan, A., Murray, C., Daley, J. F., Schlossman, S. F., Ritz, J. (1985) Generation of monoclonal antibodies to a human natural killer clone. Characterization of two natural killer-associated antigens, NKH1A and NKH2, expressed on subsets of large granular lymphocytes. J. Clin. Invest. 75, 932-943.
36. Morimoto, C., Letvin, N. L., Boyd, A. W., Hagan, M., Brown, H. M., Kornacki, M. M., Schlossman, S. F. (1985) The isolation and characterization of the human helper inducer T cell subset. J. Immunol. 134, 3762-3769.
37. Morimoto, C., Letvin, K. L., Distaso, J. A., Aldrich, W. R., Schlossman, S. F. (1985) The isolation and characterization of the human suppressor inducer T cell subset. J. Immunol. 134, 1508-1515.
38. Noro, N., Yoshioka, A., Adachi, M., Yasuda, K., Masuda, T., Yodoi, J. (1986) Monoclonal antibody (H107) inhibiting IgE binding to FcεR(+) human lymphocytes. J. Immunol. 137, 1258-1263.
39. Koopman, C., De Graaff, M., Huysmans, A. C. L. M., Meiijer, C. J. L. M., Pals, S. T. (1992) Induction of homotypic T cell adhesion by triggering of leukocyte function-associated antigen-1 (CD11a): differential effects on resting and activated T cells. Eur. J. Immunol. 22, 1851-1856.
40. Miedema, F., Tetteroo, P. A. T., Terpstra, F. G., Keizer, G., Roos, M., Weening, R. S., Weemaes, C. M. R., Roos, D., Melief, C. J. M. (1985) Immunologic studies with LFA-1- and Mo-1-deficient lymphocytes from a patient with recurrent bacterial infections. J. Immunol. 134, 3075-3081.
41. Ikewaki, N., Takabe, S., Tsuji, K. (1992) Development and characterization of a human monoclonal antibody probably detecting the leukocyte differentiation antigen CD39. Tissue Antigens 39, 174-181.
42. Ikewaki, N., Sasahara, T., Tamauchi, H., Inoko, H. (1993) Establishment of monoclonal antibody NI-58 which inhibits homotypic cell adhesion of LPS-stimulated U937 cells. Jpn. J. Bacteriol. 48, 429-433.
43. De Fougerolles, A. R., Stacker, S. A., Schwating, R., Springer, T. A. (1991) Characterization of ICAM-2 and evidence for a third counter-receptor for LFA-1. J. Exp. Med. 174, 253-267.
44. De Fougerolles, A. R., Springer, T. A. (1992) Intercellular adhesion molecule 3, third adhesion counter-receptor for lymphocyte function-associated molecule 1 on resting lymphocytes. J. Exp. Med. 175, 185-190.
45. Parham, P., Androlewitz, M. J., Brodsky, F. M., Holmes, N. J., Ways, J. P. (1982) Monoclonal antibodies: purification, fragmentation and application to structural and functional sites of MHC class I antigens. J. Immunol. Meth. 53, 133-138.
46. Jaffe, E. A., Nachman, R. L., Becker, C. G., Minick, C. R. (1973) Culture of human endothelial cells derived from umbilical veins: Identification by morphologic and immunologic criteria. J. Clin. Invest. 52, 2745-2756.
47. Rothlein, R., Springer, A. (1986) The requirement for lymphocyte function-associated antigen 1 in homotypic leukocyte adhesion stimulated by phorbol ester. J. Exp. Med. 163, 1132-1149.
48. Gitlin, G., Bayer, E. A., Wilchek, M. (1987) Studies of biotin-binding site of avidin. Biochem. J. 242, 923-926.
49. Springer, T. A. (1990) Structure and function of leukocyte integrins. Immunol. Rev. 114, 181-217.
50. Gronberg, A., Halapi, E., Ferm, M., Petersson, M., Patarroyo, M. (1993) Regulation of lymphocyte aggregation and proliferation through adhesion molecule CD54 (ICAM-1). Cell. Immunol. 147, 12-24.
51. Koopman, G., De Graaff, M., Huysmans, A. C. L. M., Meiijer, C. J. L. M., Pals, S. T. (1992) Induction of homotypic T cell adhesion by triggering of leukocyte function-associated antigen-1 (CD11a): differential effects on resting and activated T cells. Eur. J. Immunol. 22, 1851-1856.
52. Koopman, G., Van Kooyk, Y., De Graaff, M., Meyer, C. J. L. M., Figdor, C. G., Palas, S. T. (1990) Triggering of the CD44 antigen on the T lymphocyte promotes T-cell adhesion through the LFA-1 pathway. J. Immunol. 145, 3589-3593.
53. Melero, I., Balboa, M. A., Alonso, J. L., Yagu, E., Pivel, J. P., Sanchez-Madrid, F., Lopez-Botet, M. (1993) Signaling through the LFA-1 leukocyte integrin actively regulates intercellular adhesion and tumor necrosis factor-α production in natural killer cells. Eur. J. Immunol. 23, 1859-1865.
54. Haskard, D., Cavender, D., Ziff, M. (1986) Phorbol ester-stimulated T lymphocytes show enhanced adhesion to human endothelial cell monolayers. J. Immunol. 137, 1429-1434.
55. Dustin, M. L., Springer, T. A. (1989) T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1. Nature 341, 619-624.
56. Vennegoor, C. J. C. M., Kemenade, E. W., Huijbens, R. J. F., Sanchez-Madrid, F., Melief, C. J. M., Figdor, C. G. (1992) Role of LFA-1 and VLA-4 in the adhesion of cloned normal and LFA-1(CD11a/CD18)-deficient T cells to cultured endothelial cells: Identification for a new adhesion pathway. J. Immunol. 148, 1093-1101.
57. Hemler, M. E., Huang, C., Takada, Y., Schwarz, L., Strominger, J. L., Clabby, M. L. (1987) Characterization of the cell surface heterodimer VLA-4 and related peptides. J. Biol. Chem. 262, 11478-11485.
58. Wayner, E. A., Garcia-Pardo, A., Humphries, M. J., McDonald, J. A., Carter, W. G. (1989) Identification and characterization of the T lymphocyte adhesion receptor for an alternative cell attachment domain (CS-1) in plasma fibronectin. J. Cell Biol. 109, 1321-1330.