Characterization of iturin synthetase in the wild-type Bacillus subtilis strain producing iturin and in an iturin deficient mutant

FEMS Microbiology Letters

Volumn 136, Issue 2, 1996, Pages 117-122

  Feignier, Christine ^a   Besson, Françoise ^a   Michel, Georges ^a  

^a UNIVERSITÉ LYON 1   (France)

Author keywords

Affinity chromatography; Amino acid activating enzyme; Bacillus subtilis; Iturin synthetase multi enzyme complex

Indexed keywords

ANTIFUNGAL AGENT; ITURIN; ITURIN SYNTHETASE; UNCLASSIFIED DRUG;

ARTICLE; BACILLUS SUBTILIS; BACTERIUM MUTANT; BIOSYNTHESIS; CHROMATOGRAPHY; CONTROLLED STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PURIFICATION;

EID: 0029940789     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-1097(95)00485-8     Document Type: Article

References (14)

1. Peypoux, F., Guinand, M., Michel, G., Delcambe, L., Das, B.C. and Lederer, E. (1978) Structure of iturin A, an antibiotic from Bacillus subtilis. Biochemistry 17, 3992-3996.
2. Isogaï, A., Takayama, S., Murakoshi, S. and Suzuki, A. (1982) Structures of β-amino acids in antibiotics iturin A. Tetrahedron Lett. 23, 3065-3068.
3. Hosono, K. and Suzuki, H. (1983) Acylpeptides, the inhibitors of cyclic adenosine 3′, 5′-monophosphate phosphodiesterase. II. Amino acid sequence and location of lactone linkage. J. Antibiot. 36, 673-678.
4. Besson, F., Tenoux, I., Hourdou, M.L. and Michel, G. (1992) Synthesis of β-hydroxy fatty acids and β-amino fatty acids by the strains of Bacillus subtilis producing iturinic antibiotics. Biochim. Biophys. Acta 1123, 51-58.
5. + mutants. FEMS Microbiol. Lett. 127, 11-15.
6. Kleinkauf, H. and von Dohren, H. (1990) Non ribosomal biosynthesis of peptide antibiotics. Eur. J. Biochem., 192, 1-15.
7. Besson, F. and Michel, G. (1992) Biosynthesis of bacillomycin D by Bacillus subtilis: Evidence for amino acid activating enzymes by the use of affinity chromatography. FEBS Lett. 308, 18-21.
8. Besson, F. and Michel, G. (1992) Biosynthesis of iturin and surfactin by Bacillus subtilis: Evidence for amino acid activating enzymes. Biotechnol. Lett. 14, 1013-1018.
9. Froyhov, O. (1974) Bacitacin biosynthesis by three complementary fractions from Bacillus subtilis. FEBS Lett. 44, 75-78.
10. Pass, L., Zimmer, T.L. and Laland, S.G. (1973) The use of affinity chromatography in determining the sites of protein-protein interaction relative to the binding sites substrates in gramicidin S synthetase. Eur. J. Biochem. 40, 43-48.
11. Besson, F. (1994) Characterization of the surfactin synthetase isolated from the Bacillus subtilis producing iturin. Biotechnol. Lett. 12, 1269-1274.
12. Bradford, M.M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of proteins utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
13. Stulberg, M.P. and Novelli, G.D. (1960) Amino-acid-activating enzymes: methods of assay. Methods Enzymol. 5, 703-707.
14. Menkhaus, M., Ullrich, C, Kluge, B., Vater, J., Vollenbroich, D. and Kam, R.M. (1993) Structural and functional organization of the surfactin synthetase multienzyme system. J. Biol. Chem., 268, 7678-7684.